GOS:embryo development

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This page displays the top molecular interactions and top single events that were mentioned in the literature for embryo development. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryo development. They are ordered first by their pain relevance and then by number of times they were reported for embryo development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to embryo development Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 1 0.49 0.67 2.69
2 INT251147 Binding of Grin2b and Dlg2 1 1 0.33 2.75 2.43
3 INT107578 Kitl Negative_regulation of Grin2b 1 1 0.12 2.05 2.36
4 INT302646 ARSA Positive_regulation of TGFB1 1 1 0.10 0.52 1.76
5 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 1 3 0.38 4.29 1.71
6 INT93470 Notch1 Positive_regulation of Localization of Prkcg 1 2 0.09 0.31 1.65
7 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 1 4 0.47 1.01 1.63
8 INT111076 Psen1 Regulation of Psenen 2 1 0.17 0.76 1.58
9 INT168608 Binding of Grin2b and Mmp9 1 1 0.22 0.41 1.57
10 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 1 0.22 1.11 1.54
11 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 1 0.02 0.07 1.49
12 INT93782 Racgap1 Positive_regulation of Rgs9 1 1 0.55 0.07 1.49
13 INT93783 Racgap1 Positive_regulation of Gnptab 1 1 0.02 0.07 1.49
14 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 1 0.02 0 1.46
15 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 1 0.25 0.08 1.42
16 INT299311 Binding of RPTOR and RICTOR 1 1 0.38 0.21 1.4
17 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 1 0.24 0.4 1.39
18 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 1 2 0.49 0.73 1.36
19 INT192080 Foxm1 Positive_regulation of Cnr1 1 2 0.14 0.72 1.3
20 INT154518 Binding of Ephb6 and Grin2b 1 1 0.21 0.24 1.28
21 INT52955 Binding of Slc6a3 and Pdpn 1 1 0.17 1.11 1.22
22 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 1 2 0.40 0.89 1.2
23 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 1 0.02 0.3 1.19
24 INT75483 Binding of SGCG and TGFB1 1 1 0.52 2.27 1.19
25 INT142077 TGFB1 Negative_regulation of Binding of IDO1 and 1 1 0.15 2.07 1.19
26 INT256295 Binding of Creb1 and Grin2b 1 1 0.11 1.21 1.19
27 INT65373 Notch1 Regulation of Oprd1 1 1 0.09 0 1.16
28 INT70289 Atxn2l Positive_regulation of Racgap1 1 1 0.04 0.29 1.15
29 INT122267 Prkcg Positive_regulation of Grin2b 1 1 0.26 0.61 1.14
30 INT69504 Binding of Nos1 and Gatm 1 1 0.05 0 1.13
31 INT122268 Binding of Grin2b and Grm5 1 1 0.40 0.52 1.1
32 INT256294 Binding of Grin2b and Ephb1 1 1 0.28 1.11 1.08
33 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 1 0.13 0.81 1.07
34 INT73311 Binding of Oprm1 and Pdpn 1 1 0.08 0.71 1.06
35 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 1 0.19 1.91 1.06
36 INT256293 Binding of Grin2b and Insrr 1 1 0.01 1.06 1.05
37 INT291964 Phex Regulation of Gene_expression of Grin2b 1 1 0.08 1.39 1.04
38 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 1 0.27 1.07 1.03
39 INT307047 Foxm1 Positive_regulation of Casp3 1 1 0.11 0.06 1.03
40 INT352295 Binding of P2RY2 and Agtr1a 1 1 0.01 0.08 1.02
41 INT75486 Binding of Tgfbr1 and Tgfbr2 1 1 0.10 1.94 1.02
42 INT353690 Binding of Grin2b and Ca2 1 1 0.14 1.17 1.01
43 INT221747 Gtf3a Positive_regulation of Positive_regulation of Racgap1 1 1 0.00 0.33 1
44 INT61637 Binding of P2ry2 and Gtpbp4 1 1 0.02 0.1 0.99
45 INT195668 Binding of F2 and THBD 1 7 0.08 5.67 0.98
46 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 1 0.16 1.46 0.98
47 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 1 0.00 1.04 0.95
48 INT210783 Bmp2 Positive_regulation of Tnip1 1 1 0.40 0.53 0.94
49 INT149390 Foxm1 Positive_regulation of Trpa1 1 1 0.28 0.31 0.94
50 INT116930 OPRK1 Positive_regulation of Binding of PTK2 and 1 1 0.28 0.35 0.93
51 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 1 0.01 1.17 0.93
52 INT210791 Bmp2 Positive_regulation of Net1 1 1 0.38 0.52 0.93
53 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 1 0.01 1.17 0.93
54 INT65462 Bri3 Negative_regulation of Racgap1 1 1 0.02 0.39 0.93
55 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 1 0.40 1.45 0.92
56 INT210799 Bmp2 Positive_regulation of B2m 1 1 0.35 0.52 0.92
57 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 1 0.27 0.44 0.92
58 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 1 0.43 0.6 0.92
59 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 1 0.17 1.56 0.92
60 INT13282 Fgf2 Regulation of Ngf 1 1 0.66 0.21 0.91
61 INT122266 Src Negative_regulation of Grin2b 1 1 0.27 0.43 0.91
62 INT66334 Fgf2 Regulation of Fgf1 1 1 0.37 0.17 0.9
63 INT13280 Ngf Regulation of Fgf2 1 1 0.48 0.2 0.9
64 INT108438 Grin2b Regulation of Pdyn 1 1 0.16 0.25 0.9
65 INT169477 TGFB3 Positive_regulation of Spink3 1 1 0.02 1.83 0.89
66 INT59497 Adh1 Regulation of POMC 1 1 0.03 0 0.86
67 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 1 0.20 0.17 0.85
68 INT140985 Gli3 Regulation of Ihh 1 1 0.29 0.85 0.85
69 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 1 0.00 1.57 0.85
70 INT116109 VEGFA Positive_regulation of PTK2 1 1 0.13 0.3 0.83
71 INT212290 Binding of Grin2a and Grin2b 1 2 0.20 1.36 0.82
72 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 1 0.47 1.21 0.77
73 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 1 0.14 1.21 0.77
74 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 1 0.27 0.99 0.76
75 INT161945 TGFB2 Positive_regulation of TGFBR1 2 1 0.08 0.99 0.76
76 INT144547 Binding of Mecp2 and Sin3a 1 1 0.40 0.87 0.76
77 INT161952 TGFB2 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 2 1 0.08 0.99 0.76
78 INT161482 Il1b Negative_regulation of TGFB1 1 1 0.45 1.17 0.76
79 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 1 0.21 0.97 0.74
80 INT161484 Binding of TGFB1 and Il1b 1 1 0.37 1.16 0.73
81 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 1 0.23 1.01 0.72
82 INT296285 Binding of Car1 and Grin2b 1 1 0.14 0.32 0.72
83 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 1 0.37 0.5 0.72
84 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 1 0.30 0.3 0.72
85 INT250086 Grin2b Positive_regulation of Coq7 Positive_regulation of Ltp 1 1 0.00 0.36 0.72
86 INT216654 Binding of P2ry2 and DRGX 1 1 0.01 1.59 0.71
87 INT249537 Binding of Ephb1 and Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 1 0.01 0.68 0.71
88 INT296295 Binding of Grin1 and Grin2b 1 1 0.16 0.31 0.71
89 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 1 0.03 0.29 0.71
90 INT134476 Cdk5 Regulation of Map2k1 1 1 0.69 0.88 0.71
91 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 1 0.00 0 0.7
92 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 1 0.00 0 0.7
93 INT98957 Binding of NR5A2 and SP3 1 1 0.00 0 0.7
94 INT98958 Binding of NR5A2 and SP1 1 1 0.00 0 0.7
95 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 1 0.12 0.19 0.69
96 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 1 0.02 0.64 0.68
97 INT302642 Binding of ARSA and TGFB1 1 1 0.05 0.28 0.68
98 INT354913 VDR Positive_regulation of TGFB1 1 1 0.05 1.33 0.67
99 INT152925 Aanat Positive_regulation of Nanog 1 1 0.02 0.42 0.67
100 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 1 0.18 0.07 0.66
101 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 1 0.20 0.63 0.66
102 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 1 0.18 0.07 0.66
103 INT111936 Binding of PIK3CA and PTK2 1 1 0.19 0.67 0.65
104 INT149899 Ihh Positive_regulation of Mmp7 1 1 0.04 1.69 0.65
105 INT111937 Binding of PIK3CG and PTK2 1 1 0.08 0.67 0.64
106 INT135361 Prr14 Positive_regulation of Mecp2 1 1 0.24 0.15 0.64
107 INT216644 Binding of P2ry1 and P2ry2 1 1 0.24 0.55 0.64
108 INT135363 Mecp2 Positive_regulation of Mbd1 1 1 0.50 0.15 0.64
109 INT302441 Binding of GRIN1 and Grin2b 1 1 0.10 1.27 0.63
110 INT186159 Grin2d Negative_regulation of Grin2b 1 1 0.21 0.82 0.62
111 INT224726 Negative_regulation of Binding of Fgf2 and Cia1 1 1 0.01 0.92 0.62
112 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 1 0.01 0.57 0.61
113 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 1 0.00 0.84 0.61
114 INT224727 Binding of Fgf2 and Cia1 1 1 0.01 0.91 0.61
115 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 1 0.46 0.83 0.57
116 INT195666 Binding of PROC and THBD 1 2 0.40 2.42 0.56
117 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 1 0.08 0.28 0.55
118 INT251141 Binding of Dlg4 and Grin2b 1 1 0.14 0.32 0.55
119 INT251143 Binding of Grin2b and Dlg3 1 1 0.22 0.32 0.55
120 INT164973 Binding of RASA1 and Rgs7 1 1 0.00 0 0.54
121 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 1 0.02 0.51 0.54
122 INT249479 Binding of Ephb1 and Grin2b 1 1 0.29 0.37 0.54
123 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 1 0.00 0.53 0.53
124 INT164972 Binding of RASA1 and Rgs8 1 1 0.00 0 0.53
125 INT247265 Mecp2 Regulation of Fos 1 1 0.25 0.38 0.52
126 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 1 0.01 0.83 0.52
127 INT208121 Binding of Grin2a and Grin2b 1 3 0.35 0.06 0.51
128 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 1 0.04 0.29 0.51
129 INT138353 Foxm1 Positive_regulation of Phosphorylation of Trpv1 1 1 0.10 0.31 0.51
130 INT138352 Foxm1 Positive_regulation of Trpa1 1 1 0.05 0.33 0.51
131 INT302647 ARSA Positive_regulation of TGFBR1 1 1 0.03 0.29 0.51
132 INT135360 Binding of Mecp2 and Aadac 1 1 0.03 0.19 0.51
133 INT66336 Fgf2 Regulation of Gene_expression of Npy 1 1 0.12 0.09 0.5
134 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 1 0.03 0.72 0.5
135 INT330107 Racgap1 Regulation of Positive_regulation of Nox3 1 1 0.01 0.87 0.49
136 INT86088 Foxm1 Positive_regulation of Binding of Crygs and 1 1 0.04 0 0.49
137 INT89145 TGFB1 Positive_regulation of Tcstv1 1 1 0.00 0.49 0.49
138 INT228449 PMAIP1 Negative_regulation of Fgf2 1 1 0.00 0.07 0.49
139 INT86089 Foxm1 Regulation of Binding of Crygs and 1 1 0.02 0 0.49
140 INT250080 Grin2b Positive_regulation of Ltp 1 1 0.22 0.19 0.49
141 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 1 0.16 0.21 0.49
142 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 1 0.08 0.12 0.49
143 INT165078 Binding of CTSB and Notch1 1 1 0.00 1.08 0.48
144 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 1 0.35 0.17 0.48
145 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 1 0.39 0.17 0.47
146 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 1 0.04 2.06 0.47
147 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 1 2 0.00 0.95 0.46
148 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 1 0.32 0.26 0.46
149 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 1 0.39 0.17 0.46
150 INT330108 Racgap1 Positive_regulation of Cybb 1 1 0.03 0.86 0.46
151 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 1 0.33 0.4 0.46
152 INT273235 Binding of Cdk5 and Cdk5r1 2 1 0.24 6.06 0.46
153 INT116928 PTK2 Positive_regulation of JUN 1 1 0.20 0.15 0.46
154 INT72089 TGFB2 Positive_regulation of POMC 1 1 0.11 0 0.46
155 INT66335 Fgf1 Regulation of Fgf2 1 1 0.10 0.08 0.45
156 INT191489 Positive_regulation of P2ry2 Negative_regulation of Positive_regulation of Trpv1 1 1 0.03 0.08 0.44
157 INT148377 PDP1 Positive_regulation of NOTCH1 1 1 0.44 0.64 0.44
158 INT169478 TGFB3 Positive_regulation of Tgfa 1 1 0.01 0.9 0.44
159 INT148378 CP Positive_regulation of NOTCH1 1 1 0.11 0.64 0.44
160 INT215564 Hmmr Negative_regulation of P2ry2 1 1 0.00 0 0.44
161 INT169466 TGFB3 Positive_regulation of HRAS 1 1 0.03 0.89 0.43
162 INT169465 TGFB3 Positive_regulation of MTG1 1 1 0.03 0.89 0.43
163 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 1 0.10 0.42 0.43
164 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 1 0.01 1.28 0.42
165 INT75488 Binding of TGFB1 and Tgfbr1 2 1 0.23 0.78 0.41
166 INT261652 Binding of MAPK1 and PSEN1 1 1 0.22 1.25 0.41
167 INT13283 Egf Regulation of Fgf2 1 1 0.49 0.11 0.41
168 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 1 0.00 1.12 0.41
169 INT13284 Fgf2 Regulation of Egf 1 1 0.49 0.11 0.41
170 INT52954 Binding of Pdpn and Flvcr2 1 1 0.05 0.42 0.41
171 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 1 0.22 0.09 0.41
172 INT75487 Binding of TGFB1 and Tgfbr2 1 1 0.31 0.83 0.41
173 INT296296 Binding of Grin2b and Kcnip3 1 1 0.24 0 0.4
174 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 1 0.18 0.99 0.4
175 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 1 0.32 1.8 0.4
176 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 1 0.14 0.67 0.39
177 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 1 3 0.06 0.57 0.38
178 INT334533 Binding of Foxq1 and Ngf 1 1 0.05 0.8 0.38
179 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 1 0.12 1.03 0.37
180 INT150196 Grm5 Regulation of Grin2b 1 1 0.45 0 0.36
181 INT97790 Foxm1 Negative_regulation of Gene_expression of Nos2 1 1 0.03 0.16 0.36
182 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 1 0.10 0 0.35
183 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 1 0.01 0.23 0.35
184 INT280479 Binding of Mecp2 and Sin3a 1 1 0.00 1.54 0.35
185 INT71924 Ptprs Positive_regulation of Racgap1 1 1 0.10 0 0.35
186 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 1 0.01 1.32 0.35
187 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 1 0.14 1.26 0.34
188 INT137018 Tgfb1 Positive_regulation of Pscs 1 1 0.01 0.43 0.34
189 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 1 0.01 0.43 0.34
190 INT225119 Foxm1 Regulation of Localization of TGFB1 2 1 0.01 0.63 0.34
191 INT333457 Binding of PPARA and TGFB1 1 1 0.04 0 0.34
192 INT149897 Ihh Positive_regulation of Mmp14 1 1 0.03 0.93 0.33
193 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 1 0.06 0.89 0.33
194 INT236006 HTR1A Regulation of Grin2b 1 1 0.00 0 0.33
195 INT56089 TGFB1 Regulation of SERPINE1 1 1 0.41 0.41 0.33
196 INT149895 Ihh Regulation of Localization of Mmp7 1 1 0.03 0.98 0.33
197 INT295755 Fgf2 Regulation of MMP9 1 1 0.07 0.99 0.33
198 INT149902 Ihh Positive_regulation of SGCG 1 1 0.45 0.76 0.32
199 INT330109 Binding of Racgap1 and Rac1 1 1 0.03 1.22 0.32
200 INT165580 Binding of Akt1 and Grin2b 1 1 0.02 0.2 0.32

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryo development. They are ordered first by their pain relevance and then by number of times they were reported in embryo development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
3 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
4 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
5 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
6 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
7 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
8 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
9 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
10 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
11 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
12 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
13 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
14 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
15 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
16 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
17 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
18 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
19 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
20 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
21 INT1261 Localization of Adh1 63 0.81 19.36 16.09
22 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
23 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
24 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68
25 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
26 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
27 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
28 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
29 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
30 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65
31 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
32 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67
33 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
34 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
35 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
36 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
37 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
38 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
39 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
40 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
41 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
42 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36
43 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
44 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
45 INT60285 Negative_regulation of Racgap1 27 0.56 21.71 8.14
46 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12
47 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
48 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
49 INT182750 Gene_expression of Hmgcr 61 0.58 17.23 7.4
50 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33
51 INT4438 Negative_regulation of Localization of Adh1 18 0.59 6.23 6.95
52 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
53 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86
54 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
55 INT64689 Positive_regulation of Gene_expression of Fgf2 30 0.70 12.05 6.2
56 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
57 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
58 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14
59 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
60 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
61 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
62 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
63 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
64 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
65 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
66 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
67 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
68 INT4598 Negative_regulation of Adh1 15 0.54 4.69 5.33
69 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
70 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
71 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
72 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18
73 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
74 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
75 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07
76 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
77 INT38087 Regulation of Adh1 15 0.61 4.56 4.83
78 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
79 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
80 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
81 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
82 INT119212 Positive_regulation of Nrg2 4 0.22 0.24 4.29
83 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
84 INT57642 Gene_expression of PCSK1 26 0.76 5.09 4.28
85 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
86 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
87 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
88 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
89 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
90 INT70801 Gene_expression of Hmgcr 12 0.42 3.08 4.1
91 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
92 INT57157 Gene_expression of TDGF1 5 0.75 3.97 4.02
93 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
94 INT156894 Regulation of Localization of Foxp3 1 0.45 5.1 3.85
95 INT156895 Localization of Foxp3 5 0.81 5.07 3.83
96 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
97 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
98 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
99 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
100 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
101 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
102 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54
103 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
104 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
105 INT112144 Negative_regulation of Nrg2 5 0.53 1.27 3.52
106 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
107 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49
108 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
109 INT118270 Regulation of P2RY2 16 0.45 7.02 3.45
110 INT126560 Binding of P2RY2 12 0.44 6.43 3.4
111 INT52839 Regulation of Racgap1 14 0.25 9.46 3.37
112 INT168003 Localization of Fgf2 24 0.80 12.52 3.31
113 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
114 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
115 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
116 INT143604 Regulation of Nrg1 5 0.62 1.78 3.25
117 INT61547 Regulation of Fgf2 21 0.47 7.23 3.24
118 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
119 INT164087 Gene_expression of TPI1 42 0.78 5.39 3.21
120 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
121 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
122 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
123 INT101083 Binding of Fgf2 14 0.42 4.12 3.14
124 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
125 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
126 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
127 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
128 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
129 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
130 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
131 INT65033 Negative_regulation of Fgf2 21 0.59 12.36 2.94
132 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
133 INT156896 Gene_expression of Foxp3 11 0.76 7.62 2.92
134 INT33717 Regulation of Localization of Adh1 15 0.54 3.3 2.91
135 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
136 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81
137 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
138 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
139 INT85142 Gene_expression of Gtf2i 5 0.26 2.3 2.76
140 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
141 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
142 INT156892 Positive_regulation of Foxp3 3 0.50 3.49 2.74
143 INT91284 Negative_regulation of P2ry2 8 0.25 2.66 2.71
144 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
145 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
146 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
147 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
148 INT27412 Regulation of Nanog 7 0.58 0.81 2.59
149 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
150 INT64688 Negative_regulation of Gene_expression of Fgf2 5 0.59 5.07 2.56
151 INT210058 Regulation of ELF3 11 0.29 7.93 2.51
152 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
153 INT56907 Gene_expression of Pcsk1 26 0.75 7.91 2.49
154 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45
155 INT163544 Binding of Psen1 40 0.36 15.28 2.42
156 INT70286 Negative_regulation of Positive_regulation of Racgap1 2 0.43 3.78 2.42
157 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39
158 INT113203 Regulation of Foxm1 8 0.34 7.5 2.36
159 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
160 INT54515 Positive_regulation of Positive_regulation of Racgap1 6 0.12 2.33 2.34
161 INT70283 Gene_expression of Racgap1 19 0.44 9.64 2.33
162 INT150465 Positive_regulation of Gene_expression of P2ry2 3 0.56 3.48 2.33
163 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
164 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
165 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
166 INT143597 Gene_expression of Nrg1 5 0.78 1.6 2.3
167 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
168 INT65459 Binding of Racgap1 9 0.07 4.57 2.28
169 INT130961 Gene_expression of MADCAM1 4 0.33 5.03 2.28
170 INT137977 Localization of P2RY2 5 0.80 3.07 2.27
171 INT121543 Positive_regulation of Gene_expression of PCSK1 4 0.29 1.63 2.21
172 INT3938 Localization of Rbp4 5 0.79 0.39 2.15
173 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
174 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
175 INT164085 Positive_regulation of Gene_expression of TPI1 4 0.60 0.06 2.09
176 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
177 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08
178 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
179 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
180 INT87436 Regulation of Fgf2 6 0.45 3.95 2.03
181 INT60723 Localization of Psen2 5 0.68 2.11 2.02
182 INT68829 Binding of ELF3 14 0.47 7.96 2
183 INT12965 Negative_regulation of RICTOR 3 0.37 0.32 2
184 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
185 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
186 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97
187 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
188 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
189 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
190 INT275860 Negative_regulation of Localization of TNFAIP1 1 0.03 4.41 1.91
191 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
192 INT64687 Regulation of Gene_expression of Fgf2 7 0.62 2.29 1.89
193 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
194 INT95467 Transcription of P2ry2 7 0.49 1.43 1.87
195 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
196 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
197 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85
198 INT62692 Localization of Nanog 3 0.73 0.82 1.85
199 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
200 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
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