GOS:extracellular matrix organization

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This page displays the top molecular interactions and top single events that were mentioned in the literature for extracellular matrix organization. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for extracellular matrix organization. They are ordered first by their pain relevance and then by number of times they were reported for extracellular matrix organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to extracellular matrix organization Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 2 1 0.03 2.61 4.63
2 INT61359 TNF Positive_regulation of NFKB1 1 11 0.63 6.66 3.89
3 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 1 2 0.66 5.22 3.22
4 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 1 2 0.49 2.75 2.61
5 INT152501 Binding of Tnf and Tnfrsf1a 2 4 0.31 3 2.58
6 INT151826 Tnf Positive_regulation of TNF 2 1 0.04 3.38 2.51
7 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 1 0.54 0.85 2.44
8 INT122163 Binding of TNF and TNFRSF1B 1 6 0.44 6.06 2.41
9 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 1 3 0.26 1.99 2.36
10 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 2 1 0.03 1.19 2.3
11 INT279361 Binding of TNF and KLF1 1 4 0.00 3.72 2.19
12 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 2 1 0.25 3.81 2.19
13 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 2 1 0.30 3.8 2.19
14 INT86179 TNF Positive_regulation of Localization of IL6 1 5 0.35 1.66 2.17
15 INT148704 Binding of TNF and TNFRSF1A 1 5 0.44 3.3 2.09
16 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 1 2 0.04 2.02 2.08
17 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 1 2 0.43 2.23 2
18 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 1 2 0.49 2.23 2
19 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 2 1 0.06 1.13 1.98
20 INT87891 Agt Regulation of Cck 2 1 0.28 0 1.97
21 INT217042 IRF6 Positive_regulation of TNF 1 4 0.27 3.03 1.95
22 INT129212 RYBP Positive_regulation of Tnf 1 2 0.03 1.9 1.95
23 INT113550 Binding of FN1 and VTN 1 6 0.30 5.24 1.91
24 INT279359 Binding of ADA and TNF 1 1 0.20 2.61 1.91
25 INT134686 FSCN1 Positive_regulation of Gfap 2 1 0.00 0.71 1.89
26 INT243043 Binding of Mmp9 and Timp1 2 1 0.05 0.25 1.86
27 INT205152 Binding of CD44 and MMP9 1 23 0.35 17.13 1.85
28 INT199287 TNF Positive_regulation of Transcription of Oprm1 1 2 0.02 1.86 1.8
29 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 1 0.13 5.83 1.8
30 INT66504 Binding of Agt and Agtr1a 2 8 0.39 3.78 1.78
31 INT102160 Binding of Mmp2 and Mmp9 1 3 0.28 2.87 1.75
32 INT24817 Binding of POMC and VTN 1 8 0.42 0.39 1.71
33 INT137207 Tnf Positive_regulation of Nfkb1 2 3 0.23 2.69 1.71
34 INT167427 Mapk8 Regulation of Regulation of Tnf 1 1 0.26 2.83 1.7
35 INT89379 TNF Positive_regulation of Gene_expression of IL6 1 5 0.50 4.37 1.69
36 INT10202 Agt Positive_regulation of Avp 2 3 0.70 0 1.69
37 INT191618 Binding of App and Nf1 2 1 0.35 3.77 1.65
38 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 2 1 0.23 0.45 1.62
39 INT79778 Tlr4 Positive_regulation of Localization of TNF 1 4 0.08 4.21 1.61
40 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 2 1 0.23 0.45 1.61
41 INT167202 TNF Regulation of Gene_expression of Ngf 1 1 0.10 1.47 1.6
42 INT209853 TNF Regulation of Gene_expression of CD36 1 1 0.61 3.41 1.59
43 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 1 0.01 1.69 1.59
44 INT168609 Binding of Itgb1 and Mmp9 2 1 0.02 0.41 1.58
45 INT266406 Binding of APP and Ager 1 1 0.00 2.34 1.57
46 INT168611 Binding of Mmp9 and Ndor1 2 1 0.29 0.41 1.57
47 INT168608 Binding of Grin2b and Mmp9 2 1 0.22 0.41 1.57
48 INT130839 Gfap Positive_regulation of S100B 2 1 0.51 1.9 1.56
49 INT130838 Gfap Positive_regulation of Aqp4 2 1 0.51 1.9 1.56
50 INT198653 TNF Positive_regulation of MIF 1 1 0.15 3.81 1.55
51 INT252633 Binding of TNF and Tnfrsf1b 1 4 0.05 3.66 1.54
52 INT167201 Gtf3a Regulation of TNF 1 1 0.01 1.39 1.52
53 INT158775 Regulation of Tnf Regulation of Ephb1 2 1 0.18 0.09 1.52
54 INT158777 Tnf Regulation of Ephb1 2 1 0.18 0.09 1.51
55 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 1 0.43 1.69 1.5
56 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 1 0.03 2.83 1.46
57 INT72755 Tap1 Negative_regulation of TNF 1 1 0.43 2.45 1.46
58 INT131156 Binding of RUNX1 and TNF 1 2 0.03 3.44 1.42
59 INT261831 Mapk1 Negative_regulation of Hspg2 1 1 0.00 1.26 1.42
60 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 1 0.33 0.27 1.35
61 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 1 0.20 0.54 1.35
62 INT178986 Binding of MMP9 and TIMP1 1 4 0.47 2.58 1.33
63 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 1 0.43 1.67 1.33
64 INT186393 Binding of TNF and Tnfrsf1a 1 9 0.37 8.55 1.29
65 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 1 0.01 0.36 1.29
66 INT162482 Binding of Agt and Vta1 2 1 0.23 0 1.27
67 INT70037 TNF Regulation of IL10 1 2 0.09 2.11 1.26
68 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 1 0.00 1.58 1.26
69 INT202042 CAMK2N2 Negative_regulation of MMP9 1 1 0.01 0.73 1.25
70 INT66205 TNF Positive_regulation of TNF Positive_regulation of NFKB1 1 4 0.41 2.74 1.24
71 INT197092 TNF Regulation of VEGFA 1 4 0.21 2.78 1.22
72 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 1 0.32 2.09 1.22
73 INT70035 TNF Regulation of Negative_regulation of PRF1 1 1 0.05 1.42 1.21
74 INT70032 TNF Regulation of PRF1 1 1 0.05 1.42 1.21
75 INT70040 TNF Regulation of Negative_regulation of IL10 1 1 0.09 1.42 1.21
76 INT328743 TNF Positive_regulation of Mapk14 1 1 0.04 1.4 1.21
77 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 1 0.24 2.23 1.2
78 INT187172 RPS3AP9 Negative_regulation of MMP9 1 1 0.00 0.89 1.2
79 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 1 5 0.54 3.23 1.19
80 INT113242 TNF Regulation of Transcription of OPRM1 1 2 0.45 1.53 1.19
81 INT314196 Ngf Positive_regulation of Tnf 2 1 0.50 1.98 1.18
82 INT120205 Binding of App and Ern1 1 1 0.05 2.55 1.18
83 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 1 0.26 4.75 1.15
84 INT72754 Adamts7 Negative_regulation of TNF 1 1 0.28 1.64 1.13
85 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 1 6 0.25 1.3 1.12
86 INT108409 AGT Positive_regulation of AGTR2 1 2 0.31 1.49 1.11
87 INT134487 Positive_regulation of TGFBI Positive_regulation of Ltp 1 1 0.03 1.19 1.11
88 INT107264 Binding of TNF and NCR3 1 1 0.30 1.42 1.1
89 INT139704 Tnf Positive_regulation of Mapk14 2 1 0.22 0.73 1.1
90 INT107266 Binding of HLA-DRB1 and TNF 1 1 0.29 1.41 1.1
91 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 1 0.03 2.24 1.1
92 INT107267 Binding of HLA-A and TNF 1 1 0.34 1.41 1.1
93 INT2457 Agt Positive_regulation of Localization of Avp 2 5 0.59 0.2 1.09
94 INT94495 Tnf Positive_regulation of Gene_expression of Il6 2 1 0.30 1.9 1.09
95 INT151825 Tnf Positive_regulation of Mapk14 1 1 0.22 1.72 1.09
96 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 2 1 0.25 1.9 1.09
97 INT139703 Tnf Positive_regulation of Mapk8 2 1 0.32 0.73 1.08
98 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a and 2 1 0.37 0.6 1.08
99 INT168529 APP Regulation of FSIP1 1 2 0.65 2.26 1.07
100 INT119108 Binding of LTBR and TNF 1 2 0.15 1.47 1.07
101 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 1 2 0.05 1.85 1.06
102 INT116777 Psma5 Positive_regulation of Binding of Fn1 and 1 1 0.01 1.24 1.06
103 INT120312 Ghrh Regulation of Tnf 2 1 0.26 0.95 1.05
104 INT120314 Ghrh Regulation of Positive_regulation of Tnf 2 1 0.43 0.95 1.05
105 INT152504 Binding of CR1 and Tnf 2 1 0.00 0.49 1.04
106 INT133650 Epo Negative_regulation of TNF 1 1 0.35 2.7 1.04
107 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 1 0.45 0.76 1.03
108 INT81545 Tnf Positive_regulation of Gtf3a 2 2 0.03 1.41 1.02
109 INT106810 ZNF398 Positive_regulation of RECK 1 1 0.02 0.5 1.01
110 INT106809 ZNF398 Positive_regulation of Transcription of RECK 1 1 0.02 0.5 1.01
111 INT308804 Pld1 Positive_regulation of TNF 1 1 0.05 2.42 0.99
112 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 1 0.06 1.21 0.99
113 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 1 0.01 1.24 0.98
114 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 2 1 0.06 1.56 0.98
115 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 1 0.43 0.61 0.98
116 INT154255 Tnf Positive_regulation of IL1B 2 1 0.54 0.94 0.97
117 INT154254 Tnf Positive_regulation of Il6 2 1 0.36 0.94 0.97
118 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 1 0.07 1.73 0.97
119 INT187111 TIMP2 Regulation of MMP9 1 1 0.23 1.47 0.97
120 INT103133 TNF Positive_regulation of Gene_expression of IL8 1 2 0.48 1.26 0.96
121 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 1 0.35 2.64 0.96
122 INT171264 TNF Positive_regulation of MMP1 1 2 0.10 2.05 0.95
123 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 1 0.15 2.96 0.95
124 INT100018 TNF Positive_regulation of MAPK1 1 3 0.24 1.56 0.94
125 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 1 3 0.67 1.91 0.94
126 INT266659 Binding of MMP9 and MOCS1 1 1 0.01 1.71 0.94
127 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 1 0.05 1.58 0.94
128 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 1 0.01 1.04 0.94
129 INT116930 OPRK1 Positive_regulation of Binding of PTK2 and 1 1 0.28 0.35 0.93
130 INT155259 RUNX1 Negative_regulation of Tnf 2 1 0.00 1.48 0.93
131 INT159996 Prkcg Regulation of Gene_expression of App 2 1 0.42 0.32 0.92
132 INT159993 App Regulation of Gene_expression of Bace1 2 1 0.46 0.32 0.92
133 INT159994 App Regulation of Gene_expression of Prkcg 2 1 0.42 0.32 0.92
134 INT243044 Mmp8 Regulation of Mmp9 2 1 0.05 1.45 0.91
135 INT12050 Agt Positive_regulation of Localization of Oxt 2 1 0.29 0 0.91
136 INT34457 AGT Positive_regulation of POMC 1 1 0.01 0 0.91
137 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 1 0.24 1.02 0.91
138 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 1 0.14 1.24 0.91
139 INT61587 Agt Negative_regulation of REN 2 1 0.00 0.42 0.91
140 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 2 1 0.22 1.83 0.9
141 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 1 0.01 1.66 0.9
142 INT211128 Binding of P4HB and TNF 1 1 0.09 0.97 0.9
143 INT211129 Negative_regulation of Binding of P4HB and TNF 1 1 0.10 0.97 0.9
144 INT120147 Tlr4 Positive_regulation of Tnf 1 3 0.39 2.14 0.89
145 INT80132 Binding of HLA-B and TNF 1 1 0.04 1.15 0.89
146 INT142278 Slc8a1 Regulation of Tnf 2 1 0.14 0.07 0.89
147 INT166983 Binding of HLA-B and HSPG2 1 4 0.08 4.66 0.88
148 INT167466 Ccdc80 Negative_regulation of Tnf 2 1 0.01 0.76 0.88
149 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 1 0.18 0.57 0.88
150 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 2 1 0.01 1.52 0.87
151 INT209881 Binding of TNFRSF11B and TNFSF11 1 8 0.36 8.92 0.86
152 INT97795 IRF6 Positive_regulation of Localization of TNF 1 3 0.09 1.57 0.86
153 INT152868 Tnf Regulation of Gene_expression of Trpv1 2 1 0.27 0.25 0.86
154 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 1 0.47 0.74 0.85
155 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 1 0.22 1.44 0.85
156 INT196638 TNF Positive_regulation of F2RL1 1 2 0.09 1.52 0.84
157 INT69424 Binding of Agt and Oprd1 2 1 0.14 0 0.84
158 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 2 1 0.16 1.44 0.84
159 INT238641 Binding of TNF and Ifx 1 1 0.07 0.86 0.84
160 INT238642 Binding of TNF and Ada 1 1 0.03 0.86 0.84
161 INT105435 TNF Positive_regulation of IL6 1 5 0.25 4.45 0.83
162 INT167431 Binding of APP and MYO1C 1 1 0.23 1.38 0.83
163 INT192158 Binding of Mmp2 and Mmp9 2 1 0.21 0.94 0.83
164 INT149626 Il1b Regulation of Gene_expression of Tnf 1 1 0.41 0.83 0.83
165 INT106808 RECK Negative_regulation of MMP2 1 1 0.40 0.5 0.83
166 INT116109 VEGFA Positive_regulation of PTK2 1 1 0.13 0.3 0.83
167 INT309001 Ins1 Positive_regulation of Mmp9 2 1 0.20 1.96 0.83
168 INT102201 Tnf Regulation of Il1b 1 3 0.39 2.57 0.82
169 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 1 0.41 0.34 0.82
170 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 1 2 0.53 1.71 0.81
171 INT119772 Binding of Cd53 and Gfap 2 1 0.04 1.01 0.81
172 INT34458 AGT Negative_regulation of PENK 1 1 0.00 0 0.81
173 INT126555 Binding of Ighg1 and Tnf 1 1 0.35 2.2 0.8
174 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 1 0.01 1.2 0.79
175 INT147755 Binding of GNRH1 and TNF 1 1 0.32 2.37 0.79
176 INT47143 Negative_regulation of Agt Positive_regulation of Avp 2 1 0.22 0 0.79
177 INT209043 Binding of Fn1 and Slc11a1 1 3 0.03 1.91 0.78
178 INT196525 Binding of MMP2 and MMP9 1 2 0.32 2.49 0.78
179 INT110518 Tnf Positive_regulation of Prkce 2 1 0.26 1.43 0.78
180 INT188531 Binding of TNF and PDXK 1 1 0.03 1.99 0.78
181 INT102163 Binding of TNF and Mmp9 2 1 0.12 0.88 0.78
182 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 1 0.21 0.89 0.78
183 INT102161 Binding of TNF and Mmp2 1 1 0.10 0.88 0.78
184 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 1 0.09 0.89 0.78
185 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 1 0.06 1.32 0.78
186 INT102162 Binding of TNF and Adam17 1 1 0.14 0.88 0.78
187 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 1 0.03 1.37 0.77
188 INT296798 Gopc Regulation of Positive_regulation of TNF 1 1 0.01 1.37 0.77
189 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 2 1 0.46 0.48 0.77
190 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 1 0.20 1.83 0.77
191 INT164227 Binding of PAEP and Tnfrsf11b 1 1 0.00 1.18 0.77
192 INT194644 Tlr4 Positive_regulation of TNF 1 6 0.58 2.42 0.76
193 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 1 3 0.57 1.4 0.76
194 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 1 0.09 2.05 0.76
195 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 1 0.44 1.5 0.75
196 INT113472 TNF Positive_regulation of Localization of MMP14 1 1 0.47 0.45 0.75
197 INT308176 TNF Regulation of Tnfrsf1a 1 1 0.05 1.19 0.75
198 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 1 0.31 1.21 0.74
199 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 1 0.06 0.29 0.74
200 INT301141 Nsa2 Positive_regulation of TNF 1 1 0.01 0.6 0.74

Single Events

The table below shows the top 100 pain related interactions that have been reported for extracellular matrix organization. They are ordered first by their pain relevance and then by number of times they were reported in extracellular matrix organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
10 INT9660 Regulation of TNF 363 0.62 312.94 139.99
11 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71
12 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
13 INT65500 Gene_expression of App 605 0.78 429.94 98.31
14 INT10166 Localization of Tnf 237 0.81 153.95 88.64
15 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
16 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
17 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
18 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21
19 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
20 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
21 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
22 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
23 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
24 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
25 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
26 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07
27 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
28 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
29 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
30 INT13354 Transcription of TNF 108 0.72 85.81 42.32
31 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
32 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
33 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
34 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
35 INT99610 Localization of MMP9 126 0.79 48.46 32.67
36 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
37 INT35406 Localization of Tnf 94 0.81 64.63 31.65
38 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
39 INT1158 Regulation of Agt 106 0.61 29.4 30.29
40 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
41 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
42 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25
43 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
44 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
45 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
46 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
47 INT49553 Regulation of Gene_expression of Gfap 42 0.62 17.04 23.65
48 INT6866 Regulation of Gfap 51 0.61 19.6 23.56
49 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
50 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7
51 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
52 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
53 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
54 INT11625 Localization of App 98 0.78 55.46 20.86
55 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
56 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84
57 INT16794 Binding of App 103 0.48 64.87 19.79
58 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
59 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67
60 INT65502 Regulation of App 77 0.62 52.05 19.44
61 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
62 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
63 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
64 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
65 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
66 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
67 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
68 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65
69 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
70 INT2066 Localization of Agt 56 0.80 9.95 16.25
71 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
72 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78
73 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
74 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
75 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07
76 INT54052 Gene_expression of App 33 0.78 25.08 14.7
77 INT10173 Binding of Tnf 45 0.48 35.6 14.32
78 INT105156 Phosphorylation of Gfap 23 0.79 11.85 13.76
79 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
80 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
81 INT3962 Regulation of AGT 50 0.62 20.96 13.01
82 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
83 INT4199 Binding of Agt 76 0.48 21.06 12.66
84 INT137614 Gene_expression of Lgals3 70 0.77 66.13 12.53
85 INT29745 Binding of APP 47 0.48 26.49 12.4
86 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
87 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32
88 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
89 INT398 Localization of AGT 45 0.78 16.97 11.54
90 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
91 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46
92 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
93 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
94 INT8065 Binding of AGT 54 0.48 20.54 10.85
95 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
96 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
97 INT5840 Transcription of Gfap 26 0.71 18.18 10.41
98 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38
99 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35
100 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
101 INT49555 Positive_regulation of Positive_regulation of Gfap 18 0.69 11.51 10.29
102 INT113605 Negative_regulation of Gene_expression of Mmp9 25 0.41 22.92 9.98
103 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
104 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
105 INT6867 Positive_regulation of Gene_expression of GFAP 22 0.67 13.46 9.75
106 INT41569 Regulation of APP 32 0.62 17.15 9.4
107 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
108 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
109 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06
110 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
111 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
112 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
113 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
114 INT2225 Binding of Gfap 31 0.47 11.78 8.53
115 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51
116 INT8694 Binding of Lgals3 38 0.48 14.82 8.05
117 INT15725 Positive_regulation of Fn1 17 0.67 14.93 8.03
118 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
119 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
120 INT68299 Binding of Tnf 17 0.39 12.55 7.49
121 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
122 INT123459 Gene_expression of Tnfrsf11b 35 0.58 24.16 7.26
123 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
124 INT6861 Negative_regulation of Gfap 32 0.58 13.71 7.22
125 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
126 INT152030 Gene_expression of Postn 10 0.55 8.09 7.08
127 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03
128 INT168600 Binding of Mmp9 14 0.44 12.79 6.92
129 INT5839 Positive_regulation of Transcription of Gfap 10 0.49 11.61 6.74
130 INT105157 Positive_regulation of Phosphorylation of Gfap 8 0.67 6.48 6.38
131 INT123885 Positive_regulation of Lgals3 23 0.57 24.38 6.32
132 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
133 INT269144 Gene_expression of Mia1 8 0.59 11.84 6.16
134 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
135 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
136 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02
137 INT152293 Regulation of Mmp9 9 0.49 6.57 6.01
138 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
139 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
140 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
141 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
142 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
143 INT13170 Gene_expression of Comp 25 0.74 8.68 5.62
144 INT15284 Positive_regulation of Lgals3 21 0.47 8.88 5.52
145 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
146 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
147 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
148 INT106813 Positive_regulation of RECK 1 0.69 2.39 5.38
149 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
150 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
151 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
152 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
153 INT19187 Gene_expression of Lgals3 24 0.73 19.72 5.03
154 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95
155 INT17312 Binding of HSPG2 30 0.41 33.01 4.88
156 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
157 INT209893 Positive_regulation of Gene_expression of TNFRSF11B 31 0.68 11.77 4.8
158 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
159 INT53784 Positive_regulation of Regulation of Gfap 7 0.50 3.31 4.68
160 INT91463 Positive_regulation of NFKB2 19 0.40 17.7 4.6
161 INT68216 Binding of NF1 40 0.48 51.24 4.59
162 INT115927 Negative_regulation of Hspg2 27 0.57 4.16 4.53
163 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
164 INT160914 Positive_regulation of Positive_regulation of Mmp9 7 0.57 4.69 4.52
165 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46
166 INT149197 Negative_regulation of NFKB2 14 0.25 10.55 4.46
167 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
168 INT5838 Negative_regulation of Positive_regulation of Gfap 10 0.58 6.52 4.39
169 INT107771 Localization of HSPG2 10 0.78 8.47 4.3
170 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
171 INT58003 Localization of APP 32 0.80 13.75 4.2
172 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18
173 INT113282 Negative_regulation of TNFRSF11B 17 0.57 13.71 4.17
174 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12
175 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
176 INT15001 Localization of Gfap 29 0.75 6.71 4.1
177 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07
178 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
179 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
180 INT15724 Negative_regulation of Fn1 15 0.53 5.61 3.87
181 INT133312 Binding of MMP9 25 0.42 16.79 3.83
182 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
183 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
184 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75
185 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
186 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
187 INT93120 Localization of Gfap 21 0.78 8.42 3.7
188 INT134914 Binding of Gfap 21 0.37 8.25 3.67
189 INT81231 Gene_expression of LGALS3 26 0.74 9.38 3.66
190 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
191 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
192 INT106817 Gene_expression of RECK 8 0.77 2.78 3.62
193 INT15002 Regulation of Gfap 17 0.37 5.34 3.61
194 INT161206 Negative_regulation of Localization of Mmp9 10 0.59 9.68 3.59
195 INT47678 Positive_regulation of Positive_regulation of HSPG2 7 0.49 3.94 3.56
196 INT86902 Gene_expression of Mia 9 0.68 4.34 3.54
197 INT15827 Regulation of Fn1 8 0.54 4.67 3.47
198 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
199 INT66198 Negative_regulation of Gene_expression of Gfap 13 0.59 10.33 3.41
200 INT4545 Negative_regulation of Nox1 15 0.53 10.08 3.4
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