GOS:extracellular region

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This page displays the top molecular interactions and top single events that were mentioned in the literature for extracellular region. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for extracellular region. They are ordered first by their pain relevance and then by number of times they were reported for extracellular region. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to extracellular region Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 1 43 0.54 5.93 32.4
2 INT69872 Binding of MC1R and POMC 1 52 0.54 8.87 18.3
3 INT6078 Pomc Positive_regulation of Localization of Penk 3 13 0.51 0 15.49
4 INT2161 Gnrh1 Positive_regulation of Localization of LH 1 33 0.73 0.87 14.34
5 INT16531 Ghrh Positive_regulation of Localization of Gh1 2 31 0.64 2.12 14.2
6 INT69886 Ngf Positive_regulation of Calca 3 8 0.76 2.98 12.77
7 INT166591 Binding of CALCA and DCLK3 1 4 0.30 0.69 12.18
8 INT145775 Ngf Positive_regulation of Trpv1 1 11 0.72 7.71 11.25
9 INT10161 Binding of Cck and Penk 3 6 0.53 0.97 11.15
10 INT10268 Binding of PDYN and POMC 2 11 0.39 0.08 10.36
11 INT68514 Pnoc Positive_regulation of Oprl1 1 10 0.59 3.56 9.57
12 INT6079 Pomc Positive_regulation of Penk 3 9 0.43 0 9.46
13 INT77646 Binding of Ngf and Ntrk1 1 23 0.40 7.85 9.26
14 INT26468 Ghrh Positive_regulation of Localization of Gh 2 21 0.37 3.26 9.21
15 INT65724 Binding of Pnoc and Oprl1 1 8 0.33 2.94 8.82
16 INT21276 Binding of Oprd1 and Penk 1 9 0.54 1.14 8.28
17 INT2714 Pomc Positive_regulation of Localization of Prl 4 17 0.79 0.5 8.18
18 INT180785 Gdnf Positive_regulation of Calca 4 1 0.23 1.96 8.04
19 INT51205 Binding of OPRK1 and PDYN 1 7 0.00 2.01 7.8
20 INT106559 Binding of Bdnf and Ntrk2 1 23 0.43 11.09 7.33
21 INT11250 Cck Positive_regulation of Gene_expression of Fos 2 14 0.78 0.08 7.29
22 INT254001 Binding of Cxcr4 and Mif 2 1 0.52 14.17 7.18
23 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 2 6 0.76 8.19 6.66
24 INT140015 Avp Positive_regulation of Localization of Penk 2 3 0.63 3.48 6.63
25 INT188692 Binding of Cd40 and Cd40lg 2 32 0.34 22.95 6.62
26 INT26824 Crh Positive_regulation of Localization of Penk 2 7 0.54 0.42 6.49
27 INT251170 Clu Positive_regulation of Trpv1 1 1 0.28 2.61 6.49
28 INT131249 Binding of Bdnf and Ntrk2 1 11 0.41 4 6.25
29 INT31439 Penk Positive_regulation of Localization of Prl 3 8 0.55 0.23 6.24
30 INT91538 Pomc Positive_regulation of P9Ehs1 2 6 0.11 1.47 6.23
31 INT84921 Binding of NGF and NTRK1 1 13 0.50 6.39 6.1
32 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 1 8 0.74 4.31 6.1
33 INT176477 Binding of CXCR3 and CXCL10 1 14 0.25 10.61 5.87
34 INT169218 Binding of EGFR and Coc 1 1 0.06 2.8 5.85
35 INT269444 Binding of RAB5A and HHIP 1 1 0.04 0 5.79
36 INT142177 Calca Positive_regulation of Gene_expression of Igf1 3 8 0.78 3.57 5.71
37 INT79759 Ngf Regulation of Il6 2 1 0.60 4.62 5.62
38 INT140935 Binding of Cd40lg and Cd40 2 1 0.30 6.34 5.61
39 INT95068 Tlr4 Positive_regulation of IL1B 2 1 0.03 4.54 5.6
40 INT92466 Pomc Positive_regulation of Binding of Crygs and 2 8 0.06 0 5.56
41 INT20133 Trh Positive_regulation of Localization of Prl 3 23 0.78 2.04 5.44
42 INT126335 Binding of Pax3 and Tac1 1 6 0.07 6.22 5.27
43 INT88279 Ngf Positive_regulation of Ntrk1 1 5 0.76 3.06 5.23
44 INT9546 Binding of Adarb1 and Penk 1 5 0.03 0 5.1
45 INT15842 Crh Positive_regulation of Localization of Pomc 3 15 0.73 5 5.05
46 INT1310 Pomc Regulation of Localization of Prl 4 9 0.40 0.61 4.96
47 INT69888 Ngf Positive_regulation of Localization of Calca 3 4 0.52 0.51 4.95
48 INT102122 Binding of Calca and RT1-M4 2 7 0.29 5.83 4.94
49 INT11599 Calca Positive_regulation of Npr1 2 5 0.19 0.3 4.8
50 INT211710 Binding of Mc1r and a 1 7 0.44 0.37 4.78
51 INT44716 Binding of ABL2 and PDYN 1 2 0.40 0.66 4.77
52 INT10844 Ghrh Regulation of Gh 2 13 0.13 4.77 4.71
53 INT29206 Crh Regulation of Localization of POMC 2 4 0.64 0.96 4.68
54 INT24742 Binding of Calca and Vip 3 1 0.37 0.18 4.68
55 INT139706 Tnf Positive_regulation of Ltp 1 1 0.03 2.61 4.63
56 INT51497 Cck Negative_regulation of Localization of Trim13 1 1 0.34 0 4.53
57 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 2 1 0.10 1.36 4.52
58 INT128295 IL1B Positive_regulation of Insr 2 1 0.11 1.36 4.5
59 INT64718 IL1B Positive_regulation of Gene_expression of IL6 3 15 0.59 9.37 4.48
60 INT32444 Binding of Cpe and Pomc 3 2 0.22 0 4.47
61 INT38217 Penk Regulation of Localization of Avp 2 2 0.38 0.56 4.45
62 INT30423 Penk Regulation of Localization of Ins1 2 4 0.26 0.77 4.42
63 INT1390 Trh Positive_regulation of Prl 3 14 0.67 4.42 4.39
64 INT36536 PRSS1 Positive_regulation of PENK 2 1 0.24 0.86 4.39
65 INT64480 Binding of OPRL1 and PNOC 1 2 0.33 0.23 4.38
66 INT180774 Gdnf Positive_regulation of Trpv1 2 1 0.33 2.43 4.37
67 INT1392 Trh Regulation of Prl 3 15 0.29 2.47 4.29
68 INT113223 POMC Regulation of MC1R 1 6 0.68 0.39 4.24
69 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 2 1 0.55 2.97 4.23
70 INT1313 Pomc Positive_regulation of Prl 4 7 0.35 0 4.19
71 INT161109 Avp Positive_regulation of Chkb 1 1 0.12 0.18 4.19
72 INT11613 Cck Positive_regulation of Localization of Oxt 4 3 0.53 0 4.17
73 INT182194 Binding of IL8 and CXCR2 1 10 0.56 7.14 4.16
74 INT128998 Cxcl1 Positive_regulation of Localization of Calca 3 1 0.66 2.96 4.15
75 INT31440 Penk Positive_regulation of Prl 3 7 0.76 0 4.1
76 INT64756 oh Negative_regulation of Gpi1 1 1 0.03 0 4.09
77 INT16221 Ghrh Positive_regulation of Gh 2 8 0.21 1.89 4.08
78 INT29240 Binding of POMC and YY1 1 5 0.40 0.17 4.06
79 INT34220 Binding of POMC and Oprl1 1 4 0.01 0.25 4.05
80 INT11248 Gh Positive_regulation of Ghrh 2 2 0.26 0.09 4.04
81 INT2169 Penk Regulation of Localization of Prl 3 6 0.48 0 4.03
82 INT13969 Binding of Calca and Sst 3 3 0.32 0.6 4.02
83 INT95730 Binding of CP and SPINK1 3 2 0.19 5.65 4.02
84 INT101942 Binding of CD40 and CD40LG 2 16 0.23 15.24 4.01
85 INT73539 Binding of Ngf and Ngfr 1 5 0.45 3.99 4
86 INT138959 Dbi Positive_regulation of Penk 1 1 0.01 3.05 3.99
87 INT20456 Binding of Pomc and Penk 3 9 0.41 0.26 3.93
88 INT82023 Binding of Ntrk1 and Ngf 1 5 0.53 3.48 3.92
89 INT13966 Calca Positive_regulation of Localization of Sst 3 5 0.49 0.75 3.91
90 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 2 3 0.76 1 3.9
91 INT61359 TNF Positive_regulation of NFKB1 1 11 0.63 6.66 3.89
92 INT69032 IL18 Positive_regulation of IFNA1 1 12 0.23 7.87 3.83
93 INT11252 Cck Positive_regulation of Fos 2 6 0.78 0 3.79
94 INT122349 Ngf Regulation of Trpv1 1 3 0.64 1.55 3.79
95 INT180813 Ngf Positive_regulation of Sorbs1 1 1 0.04 2.09 3.79
96 INT69938 Cck Positive_regulation of Localization of Abat 2 2 0.29 0 3.78
97 INT141254 Ngf Regulation of Transcription of Trpv1 1 1 0.53 1.37 3.74
98 INT85541 Ngf Positive_regulation of Gene_expression of Calca 3 2 0.55 1.84 3.71
99 INT107331 Binding of PPBP and Adarb1 1 1 0.01 0 3.67
100 INT181455 Binding of Ccr5 and Ccl5 1 11 0.39 12.13 3.66
101 INT132862 Ngf Positive_regulation of Bdnf 2 4 0.46 4.05 3.65
102 INT15984 Binding of Avp and Oxt 3 11 0.32 1.33 3.64
103 INT34534 Binding of Penk and Oprl1 1 4 0.37 0 3.64
104 INT71069 Oprl1 Regulation of Gene_expression of Tac4 1 1 0.03 0.13 3.64
105 INT140011 Avp Positive_regulation of Dbi 1 2 0.07 0.93 3.61
106 INT29837 Gnrh1 Positive_regulation of LH 1 6 0.67 0 3.53
107 INT57985 Il1b Positive_regulation of Il6 2 5 0.59 1.66 3.53
108 INT121651 Binding of CXCL12 and CXCR4 1 13 0.48 17.61 3.52
109 INT87491 CALCA Positive_regulation of Gene_expression of IL8 2 1 0.72 0.92 3.52
110 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 1 0.27 0.17 3.48
111 INT24710 Binding of Calca and SUB1P1 2 1 0.01 2.09 3.48
112 INT180984 IRF6 Positive_regulation of Localization of IL8 1 7 0.11 2.13 3.47
113 INT108473 Binding of ADCYAP1 and PNOC 2 1 0.32 0.64 3.41
114 INT69770 Penk Negative_regulation of Pscs 1 1 0.11 0.22 3.39
115 INT73071 Binding of Cpe and Insrr 1 3 0.01 0.33 3.38
116 INT212658 KCNA1 Positive_regulation of Cort 1 1 0.00 2.58 3.36
117 INT24388 CRH Positive_regulation of Localization of POMC 2 8 0.51 5.67 3.35
118 INT7436 CFP Positive_regulation of Binding of POMC and 2 1 0.02 0.18 3.35
119 INT128292 Nts Positive_regulation of Insr 1 1 0.03 0.99 3.34
120 INT56458 Binding of GPM6A and IGHG3 1 4 0.02 0 3.31
121 INT182704 Binding of NPFF and TP53INP2 1 1 0.01 0.73 3.28
122 INT189488 Binding of Ccr1 and Ccl5 1 8 0.40 9.26 3.27
123 INT108472 Binding of NOS1 and PNOC 1 1 0.32 0.64 3.27
124 INT108471 Binding of CALCA and PNOC 2 1 0.29 0.64 3.25
125 INT354207 Igfbp7 Positive_regulation of Accn3 1 1 0.52 6.55 3.24
126 INT69823 Binding of GHR and RYBP 1 1 0.01 0 3.23
127 INT7190 Syt17 Positive_regulation of Ctsb 1 1 0.16 0 3.23
128 INT74159 Ngf Regulation of Gene_expression of Calca 3 2 0.60 1.66 3.22
129 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 1 2 0.66 5.22 3.22
130 INT3434 Vip Positive_regulation of Localization of Prl 3 6 0.76 0.16 3.21
131 INT7193 Abl2 Positive_regulation of Ctsb 1 1 0.21 0 3.21
132 INT13729 GHRH Positive_regulation of Localization of GH1 3 13 0.62 0.59 3.2
133 INT18793 Crh Regulation of Localization of Penk 2 1 0.59 0 3.2
134 INT34294 Penk Positive_regulation of Localization of Crh 2 1 0.16 0.43 3.19
135 INT91271 Mtr Regulation of Gene_expression of Il6 1 1 0.20 0 3.17
136 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 2 1 0.15 0.68 3.17
137 INT29657 Binding of Calca and Calcb 3 1 0.26 0 3.16
138 INT275850 Binding of NDUFAB1 and SNCA 1 1 0.00 3.78 3.16
139 INT17456 Binding of CSF2 and POMC 2 3 0.32 4.06 3.15
140 INT64719 IL1B Positive_regulation of IL6 3 7 0.41 6.84 3.14
141 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 3 0.31 0 3.14
142 INT128513 Pnoc Regulation of Adarb1 1 1 0.01 0.92 3.14
143 INT91539 Pomc Positive_regulation of Pomc Positive_regulation of P9Ehs1 2 1 0.03 0.84 3.13
144 INT171974 Binding of Tnfrsf11a and Tnfsf11 1 14 0.35 13.11 3.11
145 INT122780 Ngf Regulation of Gene_expression of Trpv1 1 4 0.65 3.74 3.11
146 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 1 3 0.00 0.63 3.1
147 INT30424 Penk Regulation of Localization of Sst 2 1 0.20 0 3.1
148 INT81708 POMC Regulation of Gene_expression of ITGAM 1 1 0.53 0.72 3.1
149 INT1151 Binding of CCK and GAST 2 7 0.49 0.73 3.08
150 INT208572 Binding of IL8 and CXCR1 1 6 0.33 5.2 3.08
151 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 2 0.67 2.13 3.06
152 INT36535 PRSS1 Positive_regulation of Regulation of PENK 2 1 0.23 0.54 3.06
153 INT26677 Penk Regulation of Localization of Trh 2 5 0.50 0 3.05
154 INT40660 Pdyn Positive_regulation of Localization of Prl 3 1 0.27 0 3.01
155 INT37162 Binding of Calca and Cckar 2 1 0.04 0.55 3.01
156 INT182635 Binding of CCR5 and CCL5 1 2 0.09 4.19 3
157 INT28235 Binding of Cck and Gast 3 5 0.38 0.73 2.96
158 INT202965 Binding of STC2 and BAG3 1 1 0.02 7.86 2.96
159 INT152699 Bdnf Positive_regulation of Ltp 1 5 0.05 1.22 2.95
160 INT150889 Il1a Regulation of Il10 2 1 0.22 3.49 2.95
161 INT312686 CP Positive_regulation of CP Positive_regulation of CCL20 3 1 0.03 10.97 2.94
162 INT150886 Il1a Regulation of Il1b 2 1 0.02 3.46 2.93
163 INT150888 Il1a Regulation of Il6 2 1 0.10 3.47 2.93
164 INT100835 Binding of Calca and Akap12 2 1 0.07 0.41 2.92
165 INT41152 Binding of Penk and Slc3a1 1 3 0.12 0.11 2.91
166 INT166592 Binding of CALCA and RAMP1 1 2 0.35 0.33 2.91
167 INT73821 CALCA Positive_regulation of Localization of IL8 2 1 0.25 2.37 2.91
168 INT42728 Binding of PRLR and Cpe 2 1 0.00 0 2.91
169 INT134212 CRH Regulation of Localization of POMC 2 1 0.47 2.89 2.9
170 INT318996 Binding of CCR3 and CCL5 1 1 0.07 3.39 2.9
171 INT319003 Binding of CCR1 and CCL5 1 1 0.08 3.38 2.89
172 INT69937 Cck Positive_regulation of Abat 2 2 0.31 0 2.88
173 INT221746 Ngf Positive_regulation of Ntrk1 1 1 0.02 0.92 2.88
174 INT140014 Avp Negative_regulation of Chkb 1 1 0.04 1.58 2.86
175 INT130721 Binding of IL1B and IL1RN 3 6 0.05 5.29 2.85
176 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 2 0.06 2.01 2.85
177 INT106560 Binding of Ntf3 and Ntrk2 1 3 0.14 2.47 2.84
178 INT194409 Binding of CALCA and IGKV1D-8 1 1 0.15 0 2.84
179 INT32656 Pomc Positive_regulation of Rbm39 2 1 0.08 0.42 2.84
180 INT107723 POMC Positive_regulation of MC1R 1 7 0.68 0.71 2.82
181 INT220062 Binding of NGF and TNFRSF1B 2 1 0.10 2.21 2.81
182 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 2 0.06 1.79 2.79
183 INT169134 Binding of Calca and Trpa1 2 1 0.37 3.37 2.79
184 INT83169 Binding of Cck and Lep 3 7 0.42 1.58 2.78
185 INT31513 Crh Regulation of POMC 2 3 0.29 5.06 2.78
186 INT91649 Binding of Lbp and SPECC1 1 1 0.12 2.88 2.78
187 INT186128 Binding of CD2 and CD58 1 8 0.10 7.59 2.76
188 INT190167 Binding of JUN and MMP12 1 1 0.26 0.82 2.76
189 INT137230 Trh Regulation of Gene_expression of Oprd1 1 1 0.01 1.62 2.75
190 INT23280 PRSS1 Positive_regulation of Penk 2 1 0.05 1.53 2.74
191 INT69030 IL18 Positive_regulation of IL12A 2 3 0.31 5.57 2.72
192 INT226118 Ghrl Regulation of Prkag1 2 1 0.08 0.72 2.72
193 INT69059 Klkb1 Regulation of H2-M3 Regulation of Klkb1 1 1 0.00 0.42 2.71
194 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 2 1 0.08 3.07 2.71
195 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 1 0.76 3.07 2.71
196 INT180779 Bdnf Regulation of Calca 3 1 0.09 0.23 2.71
197 INT30133 Binding of Cck and Penk 2 1 0.27 2.49 2.71
198 INT69057 H2-M3 Regulation of Klkb1 1 1 0.00 0.42 2.71
199 INT151381 St8sia1 Positive_regulation of Cck 1 1 0.19 0.45 2.7
200 INT134294 Binding of Pdyn and Penk 2 1 0.23 0 2.69

Single Events

The table below shows the top 100 pain related interactions that have been reported for extracellular region. They are ordered first by their pain relevance and then by number of times they were reported in extracellular region. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59
3 INT158 Localization of Prl 2431 0.81 378.96 952.2
4 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
5 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
6 INT292 Localization of Penk 876 0.81 88.44 669.14
7 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87
8 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
9 INT797 Regulation of Penk 812 0.62 111.13 542.24
10 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82
11 INT443 Localization of POMC 1020 0.81 284.52 443.17
12 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
13 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
14 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16
15 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81
16 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
17 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78
18 INT287 Localization of Cck 518 0.81 86.84 364.04
19 INT439 Localization of Gnrh1 976 0.81 100.96 363.25
20 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83
21 INT876 Localization of Gh1 843 0.80 67.75 340.82
22 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
23 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
24 INT2649 Regulation of Calca 433 0.62 146.05 330.95
25 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
26 INT162 Regulation of Prl 794 0.62 165.01 322.24
27 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
28 INT477 Localization of Avp 813 0.81 131.58 300.4
29 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66
30 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
31 INT3579 Localization of Oxt 555 0.81 43.35 292.44
32 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
33 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41
34 INT6852 Localization of TNF 883 0.81 705.95 270.84
35 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
36 INT1396 Binding of Penk 355 0.48 22.79 269.65
37 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
38 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
39 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
40 INT1893 Localization of Gh 1041 0.79 340.23 256.58
41 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
42 INT3948 Regulation of Cck 291 0.62 58.07 255.88
43 INT1005 Localization of Sst 385 0.81 26.31 244.56
44 INT738 Regulation of POMC 459 0.62 111.19 243.74
45 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92
46 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
47 INT1562 Localization of Crh 499 0.81 126.74 236.68
48 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47
49 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
50 INT626 Localization of CALCA 289 0.81 125.39 221.15
51 INT1308 Localization of Pomc 457 0.81 66.83 217.5
52 INT6481 Binding of TNF 624 0.48 510.2 214.82
53 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
54 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
55 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
56 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07
57 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
58 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24
59 INT528 Gene_expression of Prl 693 0.78 217.18 192.2
60 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
61 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
62 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71
63 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
64 INT4803 Transcription of Penk 435 0.72 59.09 182.4
65 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65
66 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78
67 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8
68 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
69 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77
70 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
71 INT1114 Localization of Ins1 748 0.80 192.95 165.48
72 INT2366 Binding of Cck 192 0.48 30.64 163.46
73 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
74 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
75 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37
76 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
77 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
78 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21
79 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
80 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
81 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
82 INT812 Localization of INS 1026 0.81 515.6 145.31
83 INT425 Localization of PRL 455 0.81 189.64 144.8
84 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
85 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88
86 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
87 INT9660 Regulation of TNF 363 0.62 312.94 139.99
88 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
89 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
90 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
91 INT2541 Binding of Calca 200 0.48 67.14 134.62
92 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
93 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14
94 INT695 Binding of POMC 304 0.48 56.66 126.85
95 INT5008 Localization of Calca 204 0.81 80.35 125.16
96 INT252 Localization of GH1 529 0.80 227.4 122.05
97 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64
98 INT2555 Positive_regulation of Localization of Penk 116 0.70 24.35 119.73
99 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
100 INT1026 Binding of Lbp 207 0.48 150.96 119.16
101 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03
102 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
103 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
104 INT7395 Localization of GNRH1 399 0.81 62.88 117.68
105 INT12339 Localization of IL8 437 0.81 251.87 117.39
106 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
107 INT1438 Localization of Pomc 360 0.81 101.26 116.47
108 INT4207 Regulation of Avp 267 0.62 63.72 115.33
109 INT1793 Localization of CGA 379 0.81 67.38 114.69
110 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
111 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
112 INT90 Localization of Gast 400 0.81 137.67 113
113 INT1530 Regulation of Gh 382 0.61 115.96 112.47
114 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06
115 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37
116 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
117 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2
118 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
119 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
120 INT9012 Localization of Vip 283 0.81 31.71 106.16
121 INT12082 Localization of IL6 365 0.81 241.78 105.78
122 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31
123 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74
124 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
125 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
126 INT1898 Regulation of Crh 220 0.62 61.33 102.64
127 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
128 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
129 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
130 INT397 Localization of SST 232 0.81 58.05 101.19
131 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
132 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07
133 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45
134 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
135 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
136 INT1004 Regulation of Sst 140 0.62 18.52 94.84
137 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25
138 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89
139 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
140 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84
141 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04
142 INT214 Localization of AVP 370 0.81 208.51 91.09
143 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
144 INT10166 Localization of Tnf 237 0.81 153.95 88.64
145 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13
146 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
147 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63
148 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36
149 INT4798 Gene_expression of Nts 169 0.77 29.56 86.04
150 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
151 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27
152 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
153 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
154 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
155 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02
156 INT4289 Positive_regulation of Localization of Gnrh1 202 0.70 12.3 84.01
157 INT5617 Localization of Nppa 266 0.81 83.51 83.89
158 INT339 Regulation of Trh 156 0.62 39.27 83.55
159 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29
160 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12
161 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
162 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72
163 INT6107 Localization of Npy 180 0.81 26.76 81.67
164 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
165 INT403 Localization of Trh 241 0.81 28.55 81.45
166 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
167 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49
168 INT2893 Localization of Oxt 219 0.80 28.96 79.43
169 INT3214 Localization of Ins1 527 0.80 196.9 79.26
170 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74
171 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
172 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
173 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
174 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
175 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
176 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76
177 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
178 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
179 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
180 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
181 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
182 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46
183 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
184 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
185 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
186 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
187 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
188 INT3034 Localization of Ngf 126 0.81 50.81 72.84
189 INT442 Localization of PDYN 99 0.81 11.87 72.75
190 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
191 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
192 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
193 INT8962 Gene_expression of Cpe 110 0.71 39.67 71.67
194 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
195 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26
196 INT5852 Gene_expression of Penk 167 0.78 44.44 71.13
197 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
198 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
199 INT5993 Positive_regulation of Nts 122 0.70 26.82 70.45
200 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
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