GOS:generation of precursor metabolites and energy

From wiki-pain
Jump to: navigation, search

This page displays the top molecular interactions and top single events that were mentioned in the literature for generation of precursor metabolites and energy. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for generation of precursor metabolites and energy. They are ordered first by their pain relevance and then by number of times they were reported for generation of precursor metabolites and energy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to generation of precursor metabolites and energy Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 1 52 0.54 8.87 18.3
2 INT6078 Pomc Positive_regulation of Localization of Penk 2 13 0.51 0 15.49
3 INT10268 Binding of PDYN and POMC 1 11 0.39 0.08 10.36
4 INT6079 Pomc Positive_regulation of Penk 2 9 0.43 0 9.46
5 INT2714 Pomc Positive_regulation of Localization of Prl 2 17 0.79 0.5 8.18
6 INT91538 Pomc Positive_regulation of P9Ehs1 1 6 0.11 1.47 6.23
7 INT92466 Pomc Positive_regulation of Binding of Crygs and 1 8 0.06 0 5.56
8 INT15842 Crh Positive_regulation of Localization of Pomc 2 15 0.73 5 5.05
9 INT1310 Pomc Regulation of Localization of Prl 2 9 0.40 0.61 4.96
10 INT211710 Binding of Mc1r and a 1 7 0.44 0.37 4.78
11 INT29206 Crh Regulation of Localization of POMC 1 4 0.64 0.96 4.68
12 INT32444 Binding of Cpe and Pomc 1 2 0.22 0 4.47
13 INT113223 POMC Regulation of MC1R 1 6 0.68 0.39 4.24
14 INT1313 Pomc Positive_regulation of Prl 2 7 0.35 0 4.19
15 INT29240 Binding of POMC and YY1 1 5 0.40 0.17 4.06
16 INT34220 Binding of POMC and Oprl1 1 4 0.01 0.25 4.05
17 INT20456 Binding of Pomc and Penk 2 9 0.41 0.26 3.93
18 INT24388 CRH Positive_regulation of Localization of POMC 1 8 0.51 5.67 3.35
19 INT7436 CFP Positive_regulation of Binding of POMC and 1 1 0.02 0.18 3.35
20 INT17456 Binding of CSF2 and POMC 1 3 0.32 4.06 3.15
21 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 2 3 0.31 0 3.14
22 INT91539 Pomc Positive_regulation of Pomc Positive_regulation of P9Ehs1 1 1 0.03 0.84 3.13
23 INT81708 POMC Regulation of Gene_expression of ITGAM 1 1 0.53 0.72 3.1
24 INT134212 CRH Regulation of Localization of POMC 1 1 0.47 2.89 2.9
25 INT32656 Pomc Positive_regulation of Rbm39 1 1 0.08 0.42 2.84
26 INT107723 POMC Positive_regulation of MC1R 1 7 0.68 0.71 2.82
27 INT31513 Crh Regulation of POMC 1 3 0.29 5.06 2.78
28 INT30345 Pomc Regulation of Localization of Penk 2 3 0.31 0 2.61
29 INT29446 Crh Positive_regulation of Localization of POMC 1 8 0.38 1.87 2.58
30 INT21520 Crh Regulation of Pomc 1 3 0.22 0.4 2.45
31 INT56726 Cpe Negative_regulation of Pomc 1 1 0.07 0 2.41
32 INT214144 Cck Positive_regulation of Pomc 1 1 0.15 0.94 2.39
33 INT51317 Binding of POMC and OR5D2P 1 1 0.00 0.6 2.23
34 INT34310 CRH Positive_regulation of POMC 1 3 0.42 0.62 2.21
35 INT32586 H2-Ab1 Regulation of Pomc 1 1 0.03 0.14 2.19
36 INT1315 Pomc Positive_regulation of Localization of Gnrhr 2 3 0.38 0.16 2.16
37 INT49242 Binding of Mc1r and Pomc 1 10 0.38 3.79 2.15
38 INT135868 Zfp821 Positive_regulation of Binding of ACAA1 and 1 1 0.00 0 2.11
39 INT28387 Pomc Positive_regulation of Localization of LH 2 2 0.40 0.28 2.07
40 INT138962 Dbi Positive_regulation of Pomc 2 1 0.00 1.53 2
41 INT32585 H2-Ab1 Negative_regulation of Pomc 1 1 0.03 0.13 2
42 INT60626 Crh Positive_regulation of Localization of Pomc 1 7 0.54 2.3 1.99
43 INT26948 Pomc Positive_regulation of Localization of Gh1 2 2 0.22 0.15 1.99
44 INT264953 Binding of POMC and TLR4 1 1 0.03 0.89 1.96
45 INT264947 Binding of POMC and TLR2 1 1 0.03 0.89 1.95
46 INT91607 Binding of EDN1 and POMC 1 1 0.12 0 1.9
47 INT31438 Penk Positive_regulation of Localization of Pomc 2 1 0.18 0 1.9
48 INT19496 Pomc Regulation of Localization of Ins1 1 1 0.55 0.33 1.82
49 INT26676 Pomc Regulation of Localization of Trh 2 3 0.14 0 1.73
50 INT24817 Binding of POMC and VTN 1 8 0.42 0.39 1.71
51 INT56134 CALCA Positive_regulation of POMC 1 2 0.71 0.72 1.68
52 INT45306 Pomc Positive_regulation of ENG 2 2 0.07 1.11 1.68
53 INT32442 POMC Positive_regulation of POMC Positive_regulation of ELANE 1 1 0.15 0.18 1.66
54 INT119918 Zfp821 Positive_regulation of Binding of ACAA1 and 1 1 0.00 0 1.64
55 INT32412 Penk Regulation of Pomc 2 3 0.21 0.36 1.62
56 INT86637 POMC Regulation of Gene_expression of KRT16 1 2 0.47 1.22 1.61
57 INT94270 Pomc Regulation of Transcription of Crh 2 1 0.17 0.67 1.6
58 INT66408 Pomc Positive_regulation of Regulation of HRH1 1 1 0.01 0 1.58
59 INT41652 Binding of Pomc and Oprl1 2 3 0.16 0 1.57
60 INT94271 Pomc Regulation of Avp 2 1 0.20 0.67 1.57
61 INT81710 POMC Regulation of Gene_expression of FCGR3B 1 1 0.50 0.34 1.57
62 INT81709 POMC Regulation of Gene_expression of ITGB2 1 1 0.40 0.34 1.57
63 INT81719 POMC Regulation of Gene_expression of ITGAL 1 1 0.35 0.34 1.57
64 INT81712 POMC Regulation of FCGR3B 1 1 0.16 0.34 1.56
65 INT81715 POMC Regulation of ITGB2 1 1 0.40 0.34 1.55
66 INT81721 POMC Regulation of ITGAM 1 1 0.39 0.34 1.55
67 INT81714 POMC Regulation of ITGAL 1 1 0.15 0.34 1.54
68 INT32152 POMC Positive_regulation of Gene_expression of IFNA1 1 2 0.67 0 1.53
69 INT145072 ASIP Negative_regulation of MC1R 1 1 0.29 0 1.52
70 INT23546 Negative_regulation of CNDP2 Negative_regulation of POMC Positive_regulation of POMC 1 1 0.04 0 1.52
71 INT23548 Negative_regulation of CNDP2 Negative_regulation of Localization of POMC 1 1 0.03 0 1.52
72 INT140017 Avp Positive_regulation of Gene_expression of Pomc 2 1 0.38 0.85 1.52
73 INT69709 NPL Positive_regulation of Localization of POMC 1 2 0.36 1.22 1.51
74 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 1 0.08 0.22 1.51
75 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 1 0.03 0 1.51
76 INT140008 Avp Positive_regulation of Pomc 2 1 0.38 0.84 1.51
77 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 2 1 0.02 0.36 1.5
78 INT40209 TNS3 Regulation of POMC 1 1 0.16 0.27 1.47
79 INT12691 SST Negative_regulation of Localization of POMC 1 3 0.24 1.24 1.45
80 INT1314 Pomc Regulation of Localization of Gnrhr 2 2 0.16 0.14 1.45
81 INT21425 Binding of Pomc and Gtpbp4 2 1 0.01 0.1 1.45
82 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 1 0.37 0.17 1.44
83 INT154111 POMC Positive_regulation of Localization of PENK 1 1 0.34 0.05 1.41
84 INT28992 Tmpo Positive_regulation of Pomc 2 1 0.36 3.18 1.41
85 INT154110 PENK Positive_regulation of Localization of POMC 1 1 0.34 0.05 1.41
86 INT154113 POMC Positive_regulation of YY1 1 1 0.70 0.06 1.41
87 INT27123 Binding of Pomc and Cck 2 2 0.31 0 1.38
88 INT66569 Pomc Positive_regulation of Atxn2l 1 1 0.03 0 1.36
89 INT38453 Binding of Pomc and Penk 1 1 0.17 0 1.33
90 INT2641 Binding of Pomc and Lct 1 2 0.31 0.57 1.32
91 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 1 0.03 0.19 1.32
92 INT31008 Crh Positive_regulation of Pomc 2 3 0.49 2.31 1.28
93 INT86636 POMC Positive_regulation of Gene_expression of KRT16 1 2 0.39 0.83 1.28
94 INT42579 SOD1 Negative_regulation of POMC 1 1 0.16 0.43 1.27
95 INT34052 POMC Regulation of Gene_expression of IFNG 1 1 0.11 0 1.27
96 INT5518 Pomc Negative_regulation of Crh 2 2 0.36 0.42 1.26
97 INT42580 CAT Negative_regulation of POMC 1 1 0.20 0.42 1.26
98 INT84886 APC Regulation of PPARD 1 1 0.51 1.57 1.26
99 INT46853 POMC Regulation of GAST 1 1 0.11 0.07 1.26
100 INT45269 POMC Negative_regulation of Penk 1 1 0.01 0 1.24
101 INT34471 Negative_regulation of Pomc Regulation of Slc3a1 2 1 0.05 0.12 1.24
102 INT123453 Binding of POMC and Penk 1 1 0.01 0.31 1.23
103 INT50385 Bdnf Positive_regulation of Pomc 2 1 0.22 0.47 1.23
104 INT34473 Pomc Regulation of Slc3a1 2 1 0.03 0.07 1.23
105 INT40900 PDYN Regulation of Localization of POMC 1 2 0.07 0.56 1.22
106 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 2 1 0.39 0.3 1.21
107 INT17601 Binding of POMC and Oprl1 1 1 0.01 0 1.2
108 INT83428 Binding of ADIPOQ and FRTS 1 3 0.18 2.02 1.19
109 INT35459 POMC Negative_regulation of Gene_expression of IL16 1 1 0.45 0 1.19
110 INT34661 Abat Positive_regulation of Localization of Pomc 2 1 0.04 0 1.18
111 INT43509 Avp Positive_regulation of Localization of POMC 1 2 0.13 1.26 1.16
112 INT105240 POMC Positive_regulation of Gene_expression of CXCL10 1 1 0.07 1.18 1.16
113 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 1 0.36 1.96 1.15
114 INT88778 Binding of Oprm1 and Pomc 1 3 0.21 0.56 1.14
115 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 1 0.42 1.96 1.14
116 INT13098 POMC Regulation of Localization of CGA 1 1 0.58 0 1.14
117 INT30359 Pomc Regulation of Localization of Oxt 2 1 0.03 0 1.13
118 INT59035 Binding of CPB1 and POMC 1 1 0.00 0 1.12
119 INT102421 POMC Regulation of Gene_expression of Fos 1 1 0.12 0.34 1.11
120 INT61053 Adarb1 Positive_regulation of Pomc Negative_regulation of Odc1 2 1 0.01 0 1.1
121 INT29874 OXTR Negative_regulation of POMC 1 1 0.22 0 1.1
122 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 1 0.42 1.09 1.07
123 INT69874 POMC Negative_regulation of TYRP1 1 1 0.13 0 1.07
124 INT69871 ASIP Negative_regulation of TYRP1 1 1 0.36 0 1.07
125 INT30575 SST Negative_regulation of Localization of Pomc 1 1 0.00 0.71 1.06
126 INT57508 Pomc Negative_regulation of Adarb1 2 1 0.01 0.22 1.05
127 INT58807 Pomc Negative_regulation of Localization of LH 2 2 0.06 0 1.02
128 INT19494 Pomc Positive_regulation of Localization of Ins1 1 2 0.62 0.38 1.02
129 INT101381 POMC Regulation of Localization of IL8 1 1 0.28 1.49 1.02
130 INT63103 AVP Regulation of OXT 1 1 0.28 0.68 1.02
131 INT160879 POMC Positive_regulation of DECR1 1 1 0.04 0.08 1.02
132 INT106706 POMC Negative_regulation of Binding of FN1 and 1 1 0.19 0.79 1.02
133 INT6930 Binding of Oprk1 and Pomc 1 1 0.08 0.16 1.01
134 INT21415 POMC Positive_regulation of Gene_expression of IL2 1 1 0.00 0.27 1
135 INT32327 POMC Positive_regulation of Localization of PRL 1 4 0.45 0 0.99
136 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 1 0.12 1.07 0.99
137 INT22109 Positive_regulation of Pomc Positive_regulation of Penk 2 1 0.35 0 0.99
138 INT38579 Binding of POMC and Hps4 1 1 0.00 0.32 0.99
139 INT1415 Binding of OPRM1 and POMC 1 3 0.16 0.3 0.98
140 INT31494 Pomc Regulation of Crh 2 2 0.12 0.13 0.97
141 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 1 0.29 0.43 0.95
142 INT165940 Bmp7 Positive_regulation of Pomc 1 1 0.29 0.43 0.95
143 INT43454 Pomc Regulation of Localization of Avp 2 2 0.24 0.89 0.94
144 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 1 0.06 0 0.94
145 INT106707 POMC Regulation of Binding of LAMB2 and 1 1 0.03 0.7 0.94
146 INT1654 Pomc Regulation of DSP 2 1 0.03 0 0.94
147 INT20888 POMC Positive_regulation of Localization of PDYN 1 1 0.40 0 0.92
148 INT34457 AGT Positive_regulation of POMC 1 1 0.01 0 0.91
149 INT291011 Pomc Regulation of Gene_expression of ENG 2 1 0.08 0.86 0.91
150 INT64717 Pomc Positive_regulation of Il6 2 1 0.13 0.19 0.9
151 INT62111 SLC25A4 Negative_regulation of Regulation of Ghrh 1 1 0.41 0 0.9
152 INT40636 Mif Negative_regulation of Pomc 2 1 0.25 0.07 0.9
153 INT86589 Oprd1 Regulation of Localization of Pomc 2 1 0.18 0 0.9
154 INT69870 ASIP Negative_regulation of Binding of MC1R and POMC 2 1 0.37 0 0.9
155 INT56779 Pomc Negative_regulation of Gene_expression of Odc1 2 2 0.31 0 0.89
156 INT161916 Binding of POMC and Oprd1 1 1 0.01 0 0.89
157 INT161917 Negative_regulation of Binding of POMC and Oprd1 1 1 0.01 0 0.89
158 INT264944 Binding of POMC and BOC 1 1 0.07 0.44 0.89
159 INT26991 Pomc Negative_regulation of Localization of Ins1 1 1 0.38 0 0.89
160 INT97184 Oprm1 Regulation of Gene_expression of Pomc 2 1 0.31 0 0.89
161 INT66371 Pomc Regulation of Gene_expression of Crh 2 2 0.49 0 0.88
162 INT161915 Negative_regulation of Binding of POMC and YY1 1 1 0.33 0 0.88
163 INT26987 Pomc Regulation of Ins1 1 1 0.40 0 0.87
164 INT31495 Pomc Regulation of Localization of Gnrh1 2 2 0.04 0 0.86
165 INT40742 Pomc Regulation of Localization of Gh1 2 1 0.37 0 0.86
166 INT59497 Adh1 Regulation of POMC 1 1 0.03 0 0.86
167 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 1 0.12 0.27 0.86
168 INT5451 CRH Regulation of POMC 1 2 0.28 0.39 0.85
169 INT161306 POMC Negative_regulation of Transcription of IL2 1 1 0.24 0.27 0.85
170 INT100283 TXN Negative_regulation of Gene_expression of POMC 1 1 0.54 0.5 0.85
171 INT32441 POMC Positive_regulation of ELANE 1 1 0.13 0.09 0.83
172 INT1583 PENK Negative_regulation of Binding of PENK and POMC 1 1 0.08 0 0.83
173 INT1582 Binding of PENK and POMC 1 1 0.16 0 0.83
174 INT79617 Htr1a Positive_regulation of Localization of POMC 1 1 0.38 0 0.83
175 INT19299 ANG Regulation of AVP 1 1 0.25 0 0.82
176 INT120149 Positive_regulation of Pomc Positive_regulation of Localization of Ins1 1 1 0.03 0.09 0.82
177 INT128943 Pomc Regulation of Npy 2 1 0.23 0.61 0.81
178 INT12883 Binding of IL2 and POMC 1 1 0.01 0 0.81
179 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 1 0.28 0.82 0.81
180 INT150681 Pomc Positive_regulation of Camk2a 1 1 0.47 0.07 0.8
181 INT40743 Binding of Gh1 and Pomc 2 1 0.22 0 0.8
182 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 1 0.35 0.07 0.8
183 INT276283 Atrn Positive_regulation of Binding of Mc1r and a 1 1 0.38 0.26 0.8
184 INT150679 Pomc Regulation of Gene_expression of Camk2a 1 1 0.30 0.07 0.79
185 INT240619 Binding of CRP and ADIPOQ 1 8 0.18 10.74 0.78
186 INT9527 Avp Positive_regulation of Localization of Pomc 2 7 0.58 0.29 0.77
187 INT18099 POMC Positive_regulation of Binding of Prl and 1 1 0.00 0 0.76
188 INT42929 Pomc Negative_regulation of Localization of Oxt 1 1 0.11 0 0.76
189 INT107602 Binding of OPLL and Enpp1 1 1 0.15 1.12 0.76
190 INT29913 Binding of FANCB and Pomc 2 1 0.01 0 0.76
191 INT113222 POMC Regulation of Gene_expression of MC1R 1 1 0.06 0 0.76
192 INT32163 Binding of CALM1 and POMC 1 4 0.46 0 0.75
193 INT164055 POMC Regulation of Agrp 1 1 0.29 0.3 0.75
194 INT164057 POMC Regulation of Pomc 3 1 0.09 0.3 0.75
195 INT26982 Cpe Regulation of Localization of Pomc 1 1 0.01 0 0.75
196 INT41455 Binding of Pomc and Pdyn 2 1 0.04 0 0.75
197 INT113224 Binding of ASIP and MC1R 1 1 0.00 0 0.75
198 INT124404 Binding of POMC and Oprm1 1 1 0.00 0.25 0.75
199 INT164056 Agrp Regulation of POMC 1 1 0.29 0.3 0.75
200 INT131468 Positive_regulation of POMC Positive_regulation of MC1R 1 1 0.00 0 0.74

Single Events

The table below shows the top 100 pain related interactions that have been reported for generation of precursor metabolites and energy. They are ordered first by their pain relevance and then by number of times they were reported in generation of precursor metabolites and energy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT443 Localization of POMC 1020 0.81 284.52 443.17
2 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16
3 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83
4 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
5 INT738 Regulation of POMC 459 0.62 111.19 243.74
6 INT1308 Localization of Pomc 457 0.81 66.83 217.5
7 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
8 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
9 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77
10 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
11 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37
12 INT695 Binding of POMC 304 0.48 56.66 126.85
13 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64
14 INT1438 Localization of Pomc 360 0.81 101.26 116.47
15 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84
16 INT214 Localization of AVP 370 0.81 208.51 91.09
17 INT462 Regulation of Pomc 157 0.62 41.67 67.27
18 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97
19 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48
20 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34
21 INT1463 Binding of Pomc 129 0.48 15.89 56.27
22 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3
23 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02
24 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
25 INT1295 Binding of Pomc 85 0.48 12.92 42.8
26 INT685 Regulation of AVP 124 0.62 34.9 39.91
27 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97
28 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67
29 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
30 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09
31 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01
32 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77
33 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58
34 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69
35 INT7565 Transcription of Pomc 69 0.72 14.46 27.41
36 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
37 INT2290 Protein_catabolism of POMC 41 0.99 4.86 23.36
38 INT9526 Negative_regulation of Localization of Pomc 41 0.58 6.93 23.3
39 INT55251 Gene_expression of a 142 0.67 81.21 23.03
40 INT5511 Negative_regulation of Gene_expression of Pomc 47 0.59 12.08 23.02
41 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84
42 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66
43 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07
44 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
45 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79
46 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64
47 INT1416 Transcription of POMC 40 0.72 10.71 15.38
48 INT15643 Positive_regulation of Positive_regulation of Pomc 30 0.65 4.59 15.34
49 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8
50 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59
51 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14
52 INT5515 Negative_regulation of Positive_regulation of Pomc 25 0.58 8.73 11.88
53 INT1436 Negative_regulation of Localization of Pomc 41 0.58 10.85 11.26
54 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
55 INT149138 Binding of PDX1 27 0.37 32.62 9.33
56 INT3755 Positive_regulation of GBE1 29 0.40 8.99 8.91
57 INT684 Binding of AVP 38 0.48 13.9 8.85
58 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62
59 INT16131 Negative_regulation of GBE1 37 0.30 10.32 8.15
60 INT1591 Negative_regulation of Binding of POMC 18 0.59 1.74 7.91
61 INT298 Negative_regulation of ADRB3 23 0.59 6.82 7.56
62 INT93507 Gene_expression of ASIP 14 0.60 3.98 7.55
63 INT11839 Protein_catabolism of Pomc 15 0.98 0.77 6.99
64 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37
65 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
66 INT26181 Positive_regulation of Negative_regulation of POMC 12 0.70 1.03 6.14
67 INT32532 Regulation of Positive_regulation of Pomc 11 0.61 3.2 5.93
68 INT27408 Phosphorylation of POMC 9 0.80 2.18 5.88
69 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
70 INT6276 Negative_regulation of Positive_regulation of Pomc 12 0.57 3.65 5.49
71 INT94652 Binding of a 15 0.48 4.18 5.4
72 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18
73 INT86475 Binding of ACAA1 7 0.28 1.83 5.11
74 INT14442 Localization of GBE1 19 0.31 9.09 5.03
75 INT80486 Gene_expression of FECH 13 0.54 10.42 4.8
76 INT21254 Regulation of Positive_regulation of POMC 12 0.61 3.64 4.67
77 INT14580 Regulation of Regulation of POMC 8 0.44 1.49 4.63
78 INT24820 Positive_regulation of Binding of POMC 9 0.67 2.98 4.6
79 INT7575 Regulation of Transcription of Pomc 8 0.60 1.57 4.59
80 INT10806 Positive_regulation of Transcription of Pomc 13 0.50 1.74 4.58
81 INT24420 Transcription of Pomc 13 0.69 3.32 4.54
82 INT30444 Negative_regulation of Protein_catabolism of POMC 4 0.51 2.11 4.53
83 INT22337 Negative_regulation of Transcription of Pomc 12 0.59 2.17 4.32
84 INT4104 Gene_expression of ADRB3 19 0.78 2.68 4.12
85 INT19301 Regulation of Regulation of AVP 9 0.45 3.15 4.09
86 INT178261 Positive_regulation of Gene_expression of a 23 0.55 14.67 4.07
87 INT14499 Regulation of Regulation of Pomc 7 0.61 0.15 4.06
88 INT109 Binding of ADRB3 17 0.47 3.02 3.84
89 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
90 INT16723 Regulation of GBE1 16 0.11 4.3 3.7
91 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
92 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
93 INT42523 Binding of GBE1 10 0.16 1.03 3.64
94 INT30074 Positive_regulation of Negative_regulation of Pomc 7 0.50 0.99 3.58
95 INT257727 Transcription of Vgf 1 0.72 7.38 3.52
96 INT20408 Regulation of Negative_regulation of Pomc 3 0.45 0.38 3.51
97 INT34678 Regulation of Negative_regulation of Pomc 8 0.62 1.24 3.47
98 INT133214 Regulation of PDX1 9 0.34 10.26 3.36
99 INT68445 Gene_expression of ENPP1 10 0.70 10.8 3.3
100 INT27740 Positive_regulation of COX8A 16 0.67 9.66 3.23
101 INT5508 Negative_regulation of Negative_regulation of Pomc 10 0.53 1.57 3.22
102 INT50326 Gene_expression of Vgf 11 0.78 4.41 3.2
103 INT211708 Regulation of a 4 0.42 1.92 3.15
104 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
105 INT32852 Negative_regulation of FECH 18 0.57 10.59 3.08
106 INT313753 Negative_regulation of ACOX1 10 0.45 3.76 3.04
107 INT207851 Regulation of Enpp1 5 0.45 4.42 2.96
108 INT25611 Negative_regulation of Binding of Pomc 6 0.56 1.05 2.74
109 INT171058 Negative_regulation of PDX1 5 0.32 9.31 2.72
110 INT10848 Negative_regulation of Gene_expression of AVP 13 0.59 6.76 2.71
111 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
112 INT25962 Gene_expression of COX8A 25 0.75 20.04 2.62
113 INT1586 Regulation of Binding of POMC 7 0.45 1.14 2.61
114 INT50325 Regulation of Vgf 2 0.62 4.4 2.58
115 INT33697 Regulation of Positive_regulation of Pomc 5 0.45 0.83 2.5
116 INT13748 Negative_regulation of Regulation of Pomc 4 0.41 0.63 2.5
117 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
118 INT112974 Gene_expression of Ucp1 12 0.78 7.72 2.45
119 INT46159 Positive_regulation of Positive_regulation of AVP 4 0.50 1.24 2.45
120 INT30545 Regulation of COX8A 8 0.44 7.74 2.42
121 INT208898 Gene_expression of FDX1 8 0.10 5.58 2.39
122 INT50367 Negative_regulation of COX8A 10 0.57 5.13 2.38
123 INT25438 Positive_regulation of Positive_regulation of Pomc 6 0.48 4 2.37
124 INT243496 Positive_regulation of Gene_expression of FECH 4 0.40 4.02 2.34
125 INT30372 Regulation of ADRB3 8 0.60 0.57 2.24
126 INT107597 Binding of Enpp1 5 0.37 3.35 2.23
127 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
128 INT178246 Negative_regulation of Gene_expression of a 8 0.43 4.27 2.19
129 INT34500 Positive_regulation of ADRB3 12 0.58 2.59 2.16
130 INT46160 Regulation of Positive_regulation of AVP 4 0.53 0.99 2.14
131 INT68865 Gene_expression of ACOX1 13 0.52 5.49 2.09
132 INT178260 Positive_regulation of a 6 0.50 3.09 2.08
133 INT28356 Positive_regulation of NRF1 2 0.06 1.17 2.08
134 INT123588 Localization of Vgf 3 0.81 2.35 2.07
135 INT91608 Negative_regulation of ASIP 3 0.40 0.51 2.04
136 INT13294 Negative_regulation of Regulation of Pomc 5 0.38 2.83 2.01
137 INT42497 Regulation of Negative_regulation of POMC 4 0.44 0.63 1.99
138 INT7375 Negative_regulation of Positive_regulation of AVP 6 0.43 0.37 1.97
139 INT316778 Positive_regulation of Gene_expression of ENPP1 1 0.62 7.2 1.97
140 INT25952 Negative_regulation of Regulation of POMC 4 0.36 0.76 1.96
141 INT133269 Positive_regulation of PDX1 10 0.54 9.77 1.9
142 INT171059 Localization of PDX1 8 0.56 6.7 1.9
143 INT188269 Gene_expression of COX4I2 1 0.57 2.24 1.87
144 INT53567 Positive_regulation of FECH 14 0.45 11.03 1.82
145 INT88269 Binding of ASIP 4 0.19 0.41 1.82
146 INT224529 Positive_regulation of Gene_expression of Enpp1 15 0.70 12.75 1.81
147 INT41580 Negative_regulation of Negative_regulation of POMC 5 0.50 0.46 1.79
148 INT6246 Negative_regulation of Negative_regulation of Pomc 3 0.43 1.34 1.78
149 INT6722 Regulation of Binding of Pomc 4 0.45 0.17 1.75
150 INT87401 Negative_regulation of COX4I2 2 0.31 1.7 1.71
151 INT6130 Positive_regulation of Regulation of POMC 6 0.69 3.57 1.7
152 INT89008 Gene_expression of Lepr 2 0.65 5.39 1.66
153 INT119896 Negative_regulation of Gene_expression of Ucp1 4 0.58 2.36 1.57
154 INT43482 Regulation of Binding of ADRB3 4 0.60 1.06 1.54
155 INT33245 Negative_regulation of Binding of Pomc 6 0.52 0 1.52
156 INT17094 Negative_regulation of SLC25A4 3 0.41 3.82 1.52
157 INT332460 Regulation of Binding of Enpp1 1 0.05 0.78 1.5
158 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
159 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
160 INT84888 Binding of PPARD 5 0.48 2.82 1.45
161 INT32575 Negative_regulation of Protein_catabolism of Pomc 1 0.41 0.18 1.42
162 INT44683 Positive_regulation of Cyb5r4 12 0.30 6.54 1.41
163 INT10852 Transcription of AVP 3 0.69 1.75 1.41
164 INT188268 Positive_regulation of Gene_expression of COX4I2 1 0.42 1.63 1.41
165 INT178249 Regulation of Gene_expression of a 4 0.35 2.3 1.39
166 INT5466 Positive_regulation of Negative_regulation of ADRB3 2 0.44 0.17 1.39
167 INT32805 Regulation of Regulation of Pomc 2 0.42 0.1 1.35
168 INT23693 Positive_regulation of Protein_catabolism of Pomc 1 0.38 0 1.35
169 INT39580 Positive_regulation of Regulation of Pomc 3 0.49 0 1.33
170 INT73265 Regulation of NRF1 3 0.10 0.33 1.32
171 INT352585 Negative_regulation of MCHR1 1 0.23 1.71 1.32
172 INT40102 Positive_regulation of Phosphorylation of POMC 3 0.44 0.57 1.3
173 INT183065 Positive_regulation of Gene_expression of PDX1 7 0.54 6.58 1.29
174 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24
175 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16
176 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
177 INT158469 Regulation of FECH 3 0.36 1.76 1.13
178 INT115264 Binding of FECH 9 0.41 7.93 1.1
179 INT178255 Localization of a 4 0.65 0.72 1.1
180 INT54794 Binding of Lepr 1 0.01 0 1.07
181 INT34490 Negative_regulation of Localization of GBE1 3 0.01 2.08 1.02
182 INT33048 Positive_regulation of Protein_catabolism of POMC 1 0.04 0 1.02
183 INT208896 Regulation of FDX1 1 0.09 1.2 0.99
184 INT260776 Localization of Dio1 2 0.01 1.75 0.93
185 INT178252 Transcription of a 3 0.67 0.73 0.9
186 INT25539 Regulation of Gene_expression of AVP 9 0.45 2.74 0.89
187 INT123589 Positive_regulation of Positive_regulation of Vgf 7 0.50 2.92 0.88
188 INT162073 Negative_regulation of Transcription of POMC 1 0.34 0.34 0.88
189 INT111733 Binding of Asip 1 0.21 0.68 0.88
190 INT68866 Positive_regulation of ACOX1 4 0.31 4.98 0.87
191 INT131007 Positive_regulation of Transcription of Pomc 2 0.49 1.68 0.86
192 INT51704 Phosphorylation of AVP 2 0.79 0.33 0.86
193 INT51703 Positive_regulation of Phosphorylation of AVP 1 0.49 0.09 0.86
194 INT84892 Negative_regulation of Gene_expression of PPARD 2 0.43 1.85 0.83
195 INT145073 Regulation of Gene_expression of ASIP 1 0.27 0 0.83
196 INT142016 Negative_regulation of Gene_expression of CEBPA 1 0.41 0.67 0.8
197 INT142018 Gene_expression of CEBPA 1 0.75 0.66 0.8
198 INT118986 Positive_regulation of Gene_expression of ASIP 1 0.39 0.97 0.8
199 INT55560 Binding of SLC25A4 8 0.36 1.94 0.79
200 INT1852 Localization of ADRB3 3 0.75 1.02 0.79
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox