GOS:mitochondrion organization

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This page displays the top molecular interactions and top single events that were mentioned in the literature for mitochondrion organization. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitochondrion organization. They are ordered first by their pain relevance and then by number of times they were reported for mitochondrion organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to mitochondrion organization Documents TM Confidence Disease Relevance Pain Relevance
1 INT278223 Binding of NOS3 and ACSM3 1 1 0.41 6.32 1.65
2 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 1 0.02 2.66 1.4
3 INT117504 OPA1 Positive_regulation of CPP 1 1 0.09 1.09 1.13
4 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 1 0.02 0.3 1.02
5 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 1 0.02 0.54 0.87
6 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 2 1 0.22 1.44 0.85
7 INT322266 Binding of LIG4 and NOS3 1 1 0.02 2.35 0.82
8 INT332538 Binding of AD5 and Cxadr 1 1 0.08 0.98 0.76
9 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 1 0.21 1.35 0.7
10 INT246335 Fig4 Regulation of Localization of P2rx7 2 1 0.01 0 0.67
11 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 1 0.04 1.38 0.67
12 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 1 2 0.03 0.24 0.65
13 INT340298 Ea1 Positive_regulation of Ppargc1a 1 1 0.05 1.03 0.64
14 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 1 0.07 1.42 0.58
15 INT177269 Binding of CXADR and NR1H4 1 1 0.04 0 0.58
16 INT308174 Binding of TNF and P2rx7 2 1 0.02 0.84 0.56
17 INT278228 Binding of MBNL1 and NOS3 1 1 0.05 2.06 0.54
18 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 2 1 0.01 0.87 0.53
19 INT216941 P2rx7 Regulation of Ryr1 1 1 0.01 0.55 0.52
20 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 and 2 1 0.03 0 0.51
21 INT96282 Cav2 Regulation of Positive_regulation of Gabrg1 1 1 0.25 0 0.48
22 INT254360 Binding of EPAS1 and HIF1A 1 3 0.39 3.36 0.46
23 INT171123 TNF Positive_regulation of Localization of Spg7 1 1 0.01 1.35 0.46
24 INT332539 Regulation of Binding of AD5 and Cxadr 1 1 0.09 0.65 0.44
25 INT183139 Negative_regulation of Dctn6 Positive_regulation of Trpm8 1 1 0.01 0 0.43
26 INT169859 P2rx7 Regulation of Gene_expression of Grin1 2 1 0.17 0 0.43
27 INT278226 Binding of FOSB and NOS3 1 1 0.03 1.22 0.36
28 INT205704 P2rx7 Regulation of Localization of Il18 1 1 0.09 0.67 0.35
29 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 1 0.03 0.22 0.34
30 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 1 0.03 0.77 0.33
31 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 1 0.00 0.25 0.33
32 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 1 0.00 0.25 0.33
33 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 1 0.11 0.66 0.33
34 INT205711 P2rx7 Regulation of Localization of IL8 1 1 0.02 0.92 0.33
35 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 1 0.02 0.21 0.32
36 INT145682 Binding of P2rx4 and P2rx7 1 2 0.25 0.36 0.31
37 INT215789 Fig4 Positive_regulation of Localization of P2rx7 2 1 0.03 0.53 0.29
38 INT351391 Binding of Sod2 and Gtf3a 1 1 0.00 0.18 0.27
39 INT205701 P2rx7 Positive_regulation of Il1 1 1 0.04 0.8 0.25
40 INT340295 Nrf1 Regulation of Ppargc1a 2 1 0.25 0 0.24
41 INT185489 Atp5o Negative_regulation of P2rx7 2 1 0.01 0.29 0.24
42 INT171124 Spg7 Positive_regulation of NOSTRIN 1 1 0.01 0.76 0.24
43 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 1 0.02 0.13 0.23
44 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 1 0.00 0.92 0.23
45 INT281896 KNG1 Regulation of Binding of KNG1 and NOS3 1 1 0.02 0.17 0.22
46 INT281901 Binding of KNG1 and NOS3 1 1 0.05 0.17 0.22
47 INT107219 Binding of P2rx7 and Atp5o 2 1 0.03 0.07 0.21
48 INT216946 P2rx7 Regulation of Il10 1 1 0.28 0.17 0.21
49 INT309513 Binding of Xrcc6 and Htt 1 1 0.30 3.69 0.21
50 INT107223 APEH Negative_regulation of P2rx7 2 1 0.00 0.13 0.21
51 INT131963 Binding of CAV2 and ATXN2 1 1 0.04 1.39 0.21
52 INT121807 CACNA1A Regulation of CAV2 1 1 0.01 0.25 0.2
53 INT121806 PHF21A Regulation of CAV2 1 1 0.00 0.24 0.2
54 INT175908 Binding of NOS3 and ROS1 1 1 0.10 1.84 0.19
55 INT199191 Negative_regulation of Sod2 Positive_regulation of Ros1 1 1 0.08 0 0.19
56 INT301083 Binding of BCS1L and MYH7 1 1 0.36 1.53 0.19
57 INT205710 CAMP Positive_regulation of P2rx7 1 1 0.02 0.47 0.19
58 INT137417 MAPK7 Regulation of Gene_expression of NOS3 1 1 0.00 0.5 0.19
59 INT343644 Grm5 Positive_regulation of Cav2 1 1 0.05 0 0.19
60 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 1 0.23 0.1 0.18
61 INT157557 Binding of Gria2 and Nrf1 2 1 0.11 0 0.17
62 INT269333 Binding of BDKRB2 and NOS3 1 1 0.02 0 0.17
63 INT340299 Ea1 Regulation of Ppargc1a 1 1 0.03 0.41 0.16
64 INT204791 Binding of Spg7 and Nod2 1 1 0.03 0.5 0.16
65 INT157559 Nrf1 Regulation of COX5A 2 1 0.18 0 0.15
66 INT234801 RAB3GAP1 Regulation of RAB3A 1 1 0.08 1.64 0.15
67 INT208264 Park7 Negative_regulation of Pten 3 1 0.16 1.16 0.15
68 INT302676 Binding of OPA1 and MFN2 1 1 0.46 1.12 0.14
69 INT240872 Ins1 Negative_regulation of Gene_expression of Ppargc1a 1 1 0.13 0.47 0.14
70 INT332540 Cxadr Regulation of Gene_expression of AD5 1 1 0.09 0.25 0.14
71 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 1 0.29 0.38 0.13
72 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 1 0.41 0.18 0.13
73 INT269332 Binding of NOS3 and TMPO 1 1 0.01 0 0.12
74 INT317162 Binding of Bdnf and Htt 1 1 0.51 0.2 0.12
75 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 1 0.14 0.18 0.12
76 INT204996 Binding of Park7 and Pink1 1 2 0.34 1.09 0.11
77 INT74504 Binding of P2rx7 and Rp2 2 1 0.02 0.19 0.11
78 INT266900 Gene_expression of Sod2 Negative_regulation of Gene_expression of Sod1 1 1 0.11 0.41 0.11
79 INT319315 Binding of Ap2a2 and Htt 1 1 0.28 0.64 0.11
80 INT281905 Binding of AGTR2 and NOS3 1 1 0.08 0.37 0.1
81 INT302511 Binding of OPA1 and Nos3 1 1 0.02 1.57 0.1
82 INT184814 NOS3 Positive_regulation of Gene_expression of NOS1 1 1 0.09 0.54 0.1
83 INT281899 Binding of ANG and NOS3 1 1 0.12 0.37 0.1
84 INT252790 Binding of NOS1 and NOS3 1 1 0.03 0.37 0.1
85 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 1 0.01 0.46 0.09
86 INT205708 Binding of Icam1 and P2rx7 1 1 0.08 1.03 0.09
87 INT252803 Binding of NOS3 and ISYNA1 1 1 0.02 0.32 0.09
88 INT192248 Angpt1 Positive_regulation of NOS3 1 1 0.01 0.46 0.09
89 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 1 0.02 0 0.09
90 INT270824 Binding of P2rx7 and Panx1 1 1 0.34 0.15 0.09
91 INT177296 Binding of CXADR and CYP3A4 1 1 0.30 0 0.09
92 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 1 0.01 0.46 0.09
93 INT304464 Binding of P2rx7 and P2rx6 1 1 0.05 0 0.09
94 INT220237 IL1B Regulation of Gene_expression of LONP1 1 1 0.03 0 0.08
95 INT220248 IL1RN Regulation of Gene_expression of LONP1 1 1 0.04 0 0.08
96 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 1 0.00 0.08 0.08
97 INT50286 OPA1 Positive_regulation of cod 1 1 0.01 0.16 0.08
98 INT270829 P2rx7 Positive_regulation of Panx1 1 1 0.66 0.08 0.08
99 INT309390 Gene_expression of Sod2 Negative_regulation of Nos3 1 1 0.31 0.2 0.08
100 INT340420 Hmmr Regulation of P2rx7 2 1 0.01 1.12 0.08
101 INT201736 Nfkb1 Positive_regulation of Transcription of Sod2 1 1 0.01 0.93 0.08
102 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 1 0.09 1.22 0.07
103 INT302128 SOD2 Regulation of BAK1 1 1 0.09 1.22 0.07
104 INT312645 Binding of DNAJA3 and Musk 1 1 0.08 0.96 0.07
105 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 1 0.04 0.08 0.07
106 INT241400 Epas1 Positive_regulation of Gene_expression of VEGFA 1 1 0.03 1.09 0.07
107 INT297735 Cbr1 Positive_regulation of Sod2 1 1 0.11 1.28 0.07
108 INT181645 Edn1 Positive_regulation of NOS3 1 1 0.02 0.21 0.07
109 INT41172 OPA1 Positive_regulation of RTCA 1 1 0.18 0.16 0.07
110 INT243119 Binding of amd and Sod2 1 1 0.29 3.25 0.06
111 INT200212 Binding of EPAS1 and VHL 1 3 0.06 4.1 0.05
112 INT177236 Binding of NR1H4 and FAUP1 Positive_regulation of CXADR 1 1 0.00 0 0.05
113 INT178984 Gmeb1 Positive_regulation of CXADR 1 1 0.00 0 0.05
114 INT177260 CXADR Positive_regulation of SLCO1B1 1 1 0.34 0 0.05
115 INT177276 Positive_regulation of Binding of CXADR and NR1H4 1 1 0.04 0 0.05
116 INT178985 Positive_regulation of Gmeb1 Positive_regulation of CXADR 1 1 0.00 0 0.05
117 INT177282 Regulation of Binding of CXADR and NR1H4 1 1 0.02 0 0.05
118 INT177291 CXADR Positive_regulation of ABCC2 1 1 0.22 0 0.05
119 INT177295 Binding of CXADR and ABCB1 1 1 0.30 0 0.05
120 INT224310 EPAS1 Positive_regulation of CXCL12 1 1 0.02 0.63 0.05
121 INT317181 Binding of Htt and Uts2r 1 1 0.04 0 0.05
122 INT341375 Sod2 Regulation of Bcl2 1 1 0.08 1.96 0.05
123 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 2 1 0.01 1 0.05
124 INT177288 Binding of CXADR and SV2A 1 1 0.32 0 0.04
125 INT177279 Binding of CXADR and TNFRSF25 1 1 0.18 0 0.04
126 INT177268 Binding of CXADR and HLA-DRB4 1 1 0.20 0 0.04
127 INT274095 Binding of EDNRA and OPA1 1 1 0.12 0.65 0.04
128 INT177281 Binding of CA2 and CXADR 1 1 0.31 0 0.04
129 INT266902 Nfe2l2 Positive_regulation of Sod2 1 1 0.16 0.19 0.04
130 INT270825 P2rx7 Positive_regulation of Slc37a4 1 1 0.01 0 0.04
131 INT239438 Binding of OPA1 and LIPG 1 1 0.03 1.21 0.04
132 INT266898 Gtf3a Positive_regulation of Sod2 1 1 0.00 0 0.04
133 INT306527 Binding of Htt and Aifm1 1 1 0.20 0.82 0.04
134 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 1 0.06 1.04 0.04
135 INT177253 Binding of CXADR and FAUP1 1 1 0.02 0 0.04
136 INT231438 LEP Positive_regulation of Negative_regulation of NOS3 1 1 0.09 0.32 0.03
137 INT317161 Htt Regulation of Transcription of Bdnf 1 1 0.48 0.41 0.03
138 INT266903 Binding of Sod2 and Trp53 1 1 0.05 0 0.03
139 INT217858 AD5 Positive_regulation of Gene_expression of CXADR 1 1 0.17 0.65 0.03
140 INT177258 SV2A Regulation of CXADR 1 1 0.63 0 0.03
141 INT199665 Binding of Fxn and Lamtor3 1 1 0.00 0.16 0.03
142 INT181618 NOS3 Positive_regulation of INS 1 1 0.02 0.59 0.03
143 INT200311 Htt Positive_regulation of Rest 1 1 0.05 0.75 0.03
144 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 1 0.51 0.36 0.03
145 INT330484 Binding of Cxadr and Hspg2 1 1 0.18 0.52 0.03
146 INT240883 Foxo1 Positive_regulation of Ppargc1a 1 1 0.43 0.06 0.03
147 INT341376 Sod2 Regulation of Bax 1 1 0.09 0.99 0.03
148 INT260600 Binding of Ppargc1a and Siglec1 1 1 0.14 1.25 0
149 INT317301 Binding of Park2 and Park7 1 1 0.36 0.62 0
150 INT281908 VEGFA Positive_regulation of NOS3 1 1 0.14 0.14 0
151 INT183248 LPA Positive_regulation of NOS3 1 1 0.02 0 0
152 INT351099 EPAS1 Regulation of Gene_expression of CRTC1 1 1 0.00 0.8 0
153 INT177277 CXADR Positive_regulation of CYP2B6 1 1 0.47 0 0
154 INT177254 Binding of CXADR and NCOA2 1 1 0.19 0 0
155 INT286730 Creb1 Regulation of Ppargc1a 1 1 0.17 0 0
156 INT342737 Pink1 Positive_regulation of HTRA2 1 1 0.29 0.58 0
157 INT217857 Binding of CXADR and AD5 1 1 0.18 3.55 0
158 INT286728 Creb1 Regulation of Ppargc1a 1 1 0.29 0 0
159 INT204318 NOS3 Regulation of NOS3 Regulation of SIRT1 1 1 0.20 0.1 0
160 INT155996 OPA1 Positive_regulation of Transcription of Calcb 1 1 0.02 0 0
161 INT240878 Creb1 Positive_regulation of Ppargc1a 1 1 0.19 0.11 0
162 INT204325 Binding of PPARGC1A and SIRT1 1 1 0.39 0.19 0
163 INT121179 Binding of Htt and Rest 1 1 0.07 0.45 0
164 INT281897 VEGFA Regulation of VEGFA Positive_regulation of NOS3 1 1 0.04 0.09 0
165 INT312642 DNAJA3 Positive_regulation of Musk 1 1 0.08 0.37 0
166 INT339107 Binding of BCS1L and PAK1 1 1 0.01 0.08 0
167 INT276887 MTOR Regulation of Ppargc1a 1 1 0.23 0.33 0
168 INT298688 Binding of OPA1 and MFN1 1 1 0.52 2.09 0
169 INT133825 TNF Negative_regulation of NOS3 1 1 0.28 0.06 0
170 INT314133 Lep Positive_regulation of Gene_expression of Ppargc1a 1 1 0.51 0.79 0
171 INT177283 Binding of CXADR and GOPC 1 1 0.16 0 0
172 INT36328 Binding of AMPD1 and Hmgcl 2 1 0.01 1.02 0
173 INT339260 EPAS1 Positive_regulation of VEGFA 1 1 0.19 3.67 0
174 INT193014 VHL Regulation of EPAS1 1 1 0.20 0.92 0
175 INT177267 Binding of CXADR and NCOA3 1 1 0.17 0 0
176 INT317316 Park7 Positive_regulation of Protein_catabolism of Hmbs 1 1 0.11 0.68 0
177 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 1 0.32 0.08 0
178 INT215243 Binding of Rab3a and Noc2l 1 1 0.00 0.26 0
179 INT290439 Negative_regulation of Mef2c Positive_regulation of Gene_expression of Ppargc1a 1 1 0.21 0 0
180 INT302507 Binding of GLC1F and OPA1 1 1 0.01 3.76 0
181 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 1 0.02 0 0
182 INT177284 FAUP1 Positive_regulation of CXADR 1 1 0.03 0 0
183 INT249749 Nrf1 Regulation of Gene_expression of TFAM 2 1 0.01 0.06 0
184 INT240879 Ros1 Positive_regulation of Phosphorylation of Ppargc1a 1 1 0.22 0.08 0
185 INT298687 Binding of OPA1 and PARL 1 1 0.50 2.09 0
186 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 1 0.30 0.07 0
187 INT247823 Binding of Cxadr and Tjp1 1 1 0.08 0.4 0
188 INT121177 Binding of Bdnf and Htt 1 1 0.23 0.44 0
189 INT342736 Pink1 Positive_regulation of Phosphorylation of HTRA2 1 1 0.29 0.58 0
190 INT260601 Binding of ESR1 and Ppargc1a 1 1 0.01 0.48 0
191 INT155997 OPA1 Positive_regulation of Gene_expression of Calca 1 1 0.12 0 0
192 INT309521 PRKDC Regulation of Gene_expression of Htt 1 1 0.41 0.08 0
193 INT301082 Binding of BCS1L and TARM1 1 1 0.17 1.21 0
194 INT193013 VHL Regulation of Regulation of EPAS1 1 1 0.14 1.74 0
195 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 1 0.02 0 0
196 INT121180 Htt Negative_regulation of Bdnf 1 1 0.43 0.47 0
197 INT317324 Park7 Positive_regulation of Protein_catabolism of SNCAIP 1 1 0.38 0.69 0
198 INT287652 Binding of Ceacam1 and Opa1 1 1 0.26 0.7 0
199 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 1 0.18 0.08 0
200 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 1 0.51 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitochondrion organization. They are ordered first by their pain relevance and then by number of times they were reported in mitochondrion organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
2 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
3 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
4 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
5 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
6 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
7 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
8 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
9 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
10 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
11 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
12 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77
13 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
14 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
15 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
16 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
17 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
18 INT33854 Localization of OPA1 19 0.65 10.55 5.04
19 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
20 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
21 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
22 INT163358 Positive_regulation of Ppargc1a 24 0.67 12.47 4.05
23 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
24 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
25 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
26 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
27 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
28 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
29 INT70958 Binding of NOS3 19 0.37 11.84 3.29
30 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
31 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
32 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
33 INT5913 Binding of OPA1 12 0.41 9.33 2.92
34 INT292058 Positive_regulation of Cav2 7 0.67 3.43 2.89
35 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
36 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
37 INT169323 Positive_regulation of Gene_expression of Cxadr 4 0.67 4.09 2.77
38 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76
39 INT282270 Gene_expression of Cav2 11 0.57 3.53 2.72
40 INT181818 Gene_expression of Ppargc1a 50 0.78 24.33 2.71
41 INT196377 Gene_expression of Nrf1 4 0.68 5.97 2.63
42 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
43 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27
44 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17
45 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
46 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
47 INT82166 Regulation of NOS3 14 0.54 7.57 2.08
48 INT28356 Positive_regulation of NRF1 2 0.06 1.17 2.08
49 INT91594 Localization of NOS3 12 0.78 5.39 2.02
50 INT287525 Localization of CAV2 5 0.47 5.32 2
51 INT292051 Negative_regulation of Cav2 6 0.41 2.52 1.9
52 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
53 INT164254 Gene_expression of Dnaja3 1 0.57 1.1 1.83
54 INT145657 Transcription of Sod2 3 0.72 0.7 1.82
55 INT247811 Regulation of Gene_expression of Cxadr 2 0.34 2.61 1.77
56 INT107923 Regulation of Gene_expression of NOS3 11 0.61 2.73 1.73
57 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7
58 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
59 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
60 INT120227 Binding of Cxadr 17 0.45 8.02 1.51
61 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51
62 INT178615 Binding of SOD2 12 0.48 6.93 1.51
63 INT177305 Positive_regulation of Gene_expression of CXADR 7 0.48 1.1 1.51
64 INT100462 Gene_expression of Sod2 5 0.68 3.41 1.48
65 INT80784 Regulation of BCS1L 9 0.39 7.63 1.47
66 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
67 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
68 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41
69 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34
70 INT181823 Positive_regulation of Gene_expression of Ppargc1a 20 0.67 6.45 1.33
71 INT145654 Negative_regulation of Sod2 4 0.59 2.81 1.33
72 INT161903 Regulation of Cxadr 4 0.43 1.9 1.32
73 INT73265 Regulation of NRF1 3 0.10 0.33 1.32
74 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
75 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28
76 INT134061 Transcription of Sod2 5 0.68 3.46 1.19
77 INT157852 Positive_regulation of Sod2 4 0.50 2.1 1.17
78 INT121788 Localization of BCS1L 11 0.73 10.16 1.14
79 INT113865 Binding of CXADR 35 0.46 3.18 1.12
80 INT159477 Phosphorylation of NOS3 14 0.72 1.54 1.08
81 INT108997 Localization of Htt 28 0.77 3.76 1.07
82 INT107922 Positive_regulation of Gene_expression of NOS3 17 0.60 9.32 1.04
83 INT44662 Regulation of Atp7a 2 0.30 1.78 1.04
84 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
85 INT145656 Negative_regulation of Transcription of Sod2 2 0.59 0.63 0.97
86 INT95513 Transcription of Cebpa 1 0.07 0 0.97
87 INT95509 Regulation of Cebpa 1 0.06 0 0.97
88 INT95515 Regulation of Transcription of Cebpa 1 0.04 0 0.97
89 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
90 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
91 INT171118 Localization of Spg7 1 0.26 2.59 0.95
92 INT292059 Positive_regulation of Gene_expression of Cav2 3 0.42 0.88 0.92
93 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9
94 INT152876 Negative_regulation of Cav2 1 0.34 0.28 0.87
95 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
96 INT157846 Gene_expression of BCS1L 13 0.50 15.89 0.83
97 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
98 INT51855 Binding of Cebpa 2 0.23 0 0.82
99 INT142016 Negative_regulation of Gene_expression of CEBPA 1 0.41 0.67 0.8
100 INT142018 Gene_expression of CEBPA 1 0.75 0.66 0.8
101 INT103823 Positive_regulation of Gene_expression of SOD2 10 0.68 4.69 0.79
102 INT269035 Positive_regulation of Gene_expression of Nrf1 3 0.61 3.61 0.79
103 INT171112 Negative_regulation of Spg7 2 0.15 1.37 0.79
104 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
105 INT199649 Gene_expression of Fxn 12 0.72 20.9 0.74
106 INT286715 Regulation of Ppargc1a 3 0.56 2.19 0.74
107 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74
108 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72
109 INT174158 Negative_regulation of Cxadr 23 0.55 13.74 0.72
110 INT151877 Positive_regulation of Gene_expression of CAV2 2 0.40 0.39 0.72
111 INT152562 Regulation of Transcription of NOS3 1 0.23 0.34 0.71
112 INT100461 Positive_regulation of Gene_expression of Sod2 1 0.28 1 0.71
113 INT46293 Negative_regulation of Atp7a 2 0.35 1.18 0.7
114 INT55196 Positive_regulation of Nrf1 5 0.57 4.82 0.69
115 INT105052 Transcription of Atp7a 1 0.44 1.91 0.69
116 INT113866 Regulation of CXADR 7 0.59 1.67 0.67
117 INT266894 Positive_regulation of Positive_regulation of Sod2 5 0.41 3.26 0.67
118 INT112173 Regulation of Transcription of SOD2 3 0.60 2.25 0.67
119 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
120 INT108857 Transcription of SOD2 5 0.70 3.51 0.66
121 INT75719 Regulation of Cxadr 2 0.21 0.06 0.66
122 INT177316 Localization of CXADR 9 0.77 1.05 0.64
123 INT270033 Regulation of Gene_expression of Sod2 5 0.45 2.34 0.63
124 INT75718 Positive_regulation of Cxadr 2 0.32 0.31 0.62
125 INT75720 Positive_regulation of Binding of Cxadr 1 0.23 0 0.62
126 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
127 INT75717 Binding of Cxadr 1 0.17 0 0.61
128 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
129 INT60241 Negative_regulation of HMGCL 2 0.06 0.33 0.6
130 INT111960 Binding of Sod2 4 0.37 2.03 0.59
131 INT159476 Positive_regulation of Phosphorylation of NOS3 6 0.44 1.43 0.58
132 INT108856 Regulation of Gene_expression of SOD2 3 0.44 0.79 0.58
133 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
134 INT121810 Positive_regulation of CAV2 2 0.28 0.55 0.57
135 INT215340 Localization of Htt 10 0.61 5.12 0.55
136 INT79725 Regulation of Sod2 8 0.61 4.95 0.54
137 INT315028 Regulation of Cav2 2 0.43 0.86 0.54
138 INT232453 Negative_regulation of DNAJA3 1 0.41 0 0.54
139 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
140 INT181833 Negative_regulation of Ppargc1a 14 0.57 6.01 0.52
141 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
142 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
143 INT276874 Localization of Ppargc1a 3 0.73 2.28 0.49
144 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
145 INT91864 Negative_regulation of Transcription of NOS3 4 0.54 1.41 0.48
146 INT120226 Positive_regulation of Cxadr 4 0.44 2.54 0.48
147 INT73264 Gene_expression of NRF1 2 0.70 0.52 0.48
148 INT298539 Binding of CAV2 2 0.39 0.95 0.48
149 INT162009 Negative_regulation of Gene_expression of Sod2 1 0.43 1.11 0.46
150 INT247794 Localization of Cxadr 4 0.76 3.17 0.45
151 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
152 INT243418 Binding of Htt 14 0.30 5.94 0.44
153 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
154 INT144969 Binding of EPAS1 3 0.06 4.12 0.44
155 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
156 INT183138 Negative_regulation of Dctn6 1 0.01 0 0.43
157 INT158456 Positive_regulation of Localization of OPA1 1 0.43 0.34 0.43
158 INT159479 Positive_regulation of Binding of NOS3 2 0.50 0.63 0.41
159 INT70761 Localization of Atp7a 2 0.06 0.06 0.41
160 INT34976 Positive_regulation of Gene_expression of OPA1 4 0.43 4.21 0.4
161 INT171110 Gene_expression of Spg7 1 0.21 1.05 0.4
162 INT188687 Negative_regulation of Negative_regulation of Spg7 1 0.05 0.31 0.4
163 INT343628 Regulation of Positive_regulation of Cav2 1 0.19 0 0.4
164 INT171116 Negative_regulation of Gene_expression of Spg7 1 0.15 1.06 0.4
165 INT171111 Regulation of Spg7 1 0.09 0.94 0.4
166 INT119271 Positive_regulation of BCS1L 13 0.50 7.56 0.39
167 INT132864 Binding of Htt 15 0.46 2.34 0.38
168 INT340285 Positive_regulation of Localization of Ppargc1a 1 0.40 0.79 0.38
169 INT124298 Localization of Sod2 8 0.74 3.5 0.37
170 INT234828 Gene_expression of RAB3A 2 0.30 2.05 0.37
171 INT159542 Localization of SOD2 5 0.80 1.91 0.36
172 INT105051 Negative_regulation of Transcription of Atp7a 1 0.35 1.02 0.36
173 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
174 INT181829 Binding of Ppargc1a 16 0.48 9.61 0.34
175 INT38712 Gene_expression of Atp7a 3 0.39 0.77 0.34
176 INT151529 Regulation of Cav2 1 0.44 0.29 0.33
177 INT144475 Protein_catabolism of Sod2 1 0.17 0.58 0.33
178 INT134079 Phosphorylation of OPA1 1 0.16 0.22 0.33
179 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
180 INT161434 Regulation of Negative_regulation of OPA1 1 0.03 0.2 0.32
181 INT51856 Phosphorylation of Cebpa 1 0.10 0 0.31
182 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
183 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
184 INT292064 Positive_regulation of Positive_regulation of Cav2 1 0.49 0.5 0.28
185 INT240832 Regulation of Positive_regulation of Ppargc1a 3 0.44 0.49 0.27
186 INT319179 Positive_regulation of Positive_regulation of SOD2 1 0.68 0.51 0.27
187 INT232628 Gene_expression of Opa1 10 0.78 17.01 0.26
188 INT349301 Negative_regulation of PARK7 1 0.41 3.44 0.26
189 INT162010 Localization of Sod2 2 0.81 0.47 0.25
190 INT308149 Gene_expression of Slc22a5 1 0.63 2.77 0.25
191 INT109333 Negative_regulation of Gene_expression of SOD2 2 0.42 0.71 0.24
192 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
193 INT352629 Binding of MAN2A1 1 0.05 4.16 0.23
194 INT340284 Negative_regulation of Gene_expression of Nrf1 1 0.38 0 0.23
195 INT287205 Regulation of Htt 5 0.45 3.56 0.22
196 INT107450 Localization of Rab3a 1 0.22 0.62 0.22
197 INT162011 Positive_regulation of Negative_regulation of Sod2 1 0.47 0.55 0.22
198 INT193015 Positive_regulation of Gene_expression of EPAS1 6 0.32 8.77 0.21
199 INT188686 Positive_regulation of Spg7 2 0.06 0.81 0.21
200 INT157553 Gene_expression of Nrf1 2 0.28 0.47 0.21
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