GOS:nuclear envelope

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This page displays the top molecular interactions and top single events that were mentioned in the literature for nuclear envelope. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear envelope. They are ordered first by their pain relevance and then by number of times they were reported for nuclear envelope. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to nuclear envelope Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 1 0.10 2.91 6.54
2 INT73539 Binding of Ngf and Ngfr 1 5 0.45 3.99 4
3 INT48162 RIMS3 Regulation of Localization of LTC4S 2 1 0.10 2.14 3.25
4 INT118158 Binding of Prkca and Prkcz 1 1 0.07 1.14 2.98
5 INT229497 Binding of Vim and Ndel1 1 1 0.33 3.5 2.81
6 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 1 0.38 0.86 2.63
7 INT37873 Pag1 Regulation of Nrm 2 2 0.04 1.1 2.41
8 INT81657 Binding of CPOX and PTGS1 1 5 0.15 1.9 2.37
9 INT89733 Binding of Calca and Nrm 2 1 0.31 0.71 2.09
10 INT142073 Binding of Helt and Nrm 2 1 0.00 0 1.74
11 INT167765 Prkca Positive_regulation of Sigmar1 1 1 0.41 0.63 1.74
12 INT149680 Binding of Parp1 and Oprm1 1 1 0.53 0 1.66
13 INT54601 Binding of Mtor and Ache 1 1 0.20 0.8 1.58
14 INT118157 Binding of Prkca and Prkcz Positive_regulation of Binding of Prkca Prkcz 1 1 0.02 0.58 1.55
15 INT118159 Binding of Prkca and Prkcz Positive_regulation of Prkcz 1 1 0.02 0.58 1.54
16 INT118160 Binding of Prkca and Prkcz Positive_regulation of Prkca 1 1 0.11 0.58 1.54
17 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 1 0.08 1.68 1.49
18 INT222335 Binding of Bdnf and Ngfr 1 3 0.05 2.66 1.48
19 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 1 0.06 1.26 1.45
20 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 1 0.06 1.26 1.45
21 INT28992 Tmpo Positive_regulation of Pomc 2 1 0.36 3.18 1.41
22 INT229496 Binding of Ndel1 and Gopc 1 1 0.08 2.05 1.36
23 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 1 0.01 0.81 1.31
24 INT136200 Binding of Penk and NUP37 1 1 0.04 0 1.28
25 INT280480 Binding of Bdnf and Ngfr 1 5 0.25 3.14 1.27
26 INT105295 WAS Regulation of PTGS1 1 1 0.02 0.13 1.27
27 INT110542 SIGMAR1 Regulation of OPRM1 1 1 0.04 0.33 1.25
28 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 1 0.04 0.33 1.25
29 INT121000 Binding of PAG1 and Nrm 2 1 0.13 0.67 1.25
30 INT13603 Binding of NCF4 and Nrm 2 2 0.40 0.21 1.22
31 INT103031 Calca Positive_regulation of Ptgs1 1 2 0.46 0.98 1.22
32 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 1 0.03 2.4 1.18
33 INT189017 Binding of Pax3 and Lmna 2 1 0.14 0.42 1.16
34 INT76256 Binding of Slc6a3 and Sigmar1 2 1 0.20 0 1.16
35 INT35399 Binding of Alox5 and Mthfs 1 1 0.01 0 1.14
36 INT256041 Binding of Ngfr and Ntrk1 1 3 0.14 0.9 1.13
37 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 3 1 0.03 0.64 1.13
38 INT110671 Binding of Cnr1 and Alox5 3 1 0.07 0.2 1.13
39 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 3 1 0.00 0.64 1.13
40 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 3 1 0.00 0.64 1.13
41 INT110669 Binding of Alox5 and Trpv1 3 1 0.07 0.2 1.13
42 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 3 1 0.01 0.64 1.13
43 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 3 1 0.03 0.64 1.13
44 INT68165 Alox5 Positive_regulation of Pdpk1 3 1 0.01 0.63 1.12
45 INT82024 Binding of Ngfr and Ngf 1 2 0.33 1.48 1.05
46 INT312097 ELANE Regulation of ALOX5 1 1 0.08 1.75 1.05
47 INT76001 Ngf Positive_regulation of Ngfr 1 1 0.16 0.93 1.05
48 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 1 0.00 1.05 1.04
49 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 1 0.00 0.26 1.03
50 INT242642 Binding of BDNF and Ngfr 1 2 0.21 1.38 1.01
51 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 1 0.32 0.63 0.98
52 INT60213 Binding of Ptgs1 and Ptgs2 1 2 0.37 0.5 0.97
53 INT253836 Cck Regulation of DST 1 1 0.03 0.42 0.95
54 INT61037 Och Positive_regulation of Ptgs1 1 1 0.00 0 0.95
55 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 1 0.04 1.47 0.94
56 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 2 1 0.02 0 0.93
57 INT185417 Binding of ALOX5 and PLA2G2A 1 4 0.16 3.13 0.9
58 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 1 0.03 0.56 0.9
59 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 2 1 0.04 0.23 0.9
60 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 2 1 0.04 0.23 0.9
61 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 1 0.38 0.23 0.89
62 INT57746 Il1 Regulation of Gene_expression of Ltc4s 1 1 0.36 0.33 0.88
63 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 1 0.15 0 0.87
64 INT251704 Ache Regulation of Gene_expression of Acot1 1 1 0.08 1.68 0.87
65 INT161048 Nrm Positive_regulation of Prdm4 2 1 0.56 1.47 0.86
66 INT323698 Gene_expression of MIR146A Regulation of FAF1 1 1 0.16 1.82 0.86
67 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 1 0.01 1.52 0.86
68 INT73538 Ngf Positive_regulation of Ngfr 1 2 0.41 1.05 0.85
69 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 1 0.47 0.74 0.85
70 INT340294 Ea1 Positive_regulation of Sirt1 1 1 0.06 0.53 0.83
71 INT113250 Olr1259 Negative_regulation of Ache 1 1 0.01 0.38 0.83
72 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 1 0.02 0.89 0.81
73 INT62176 Binding of PTGS2 and Ptgs1 1 2 0.00 0.69 0.79
74 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 1 0.01 2.87 0.78
75 INT203164 PTGER2 Regulation of ALOX5 1 1 0.00 0.9 0.78
76 INT203171 PTGER2 Negative_regulation of ALOX5 1 1 0.01 0.89 0.77
77 INT167770 Sigmar1 Positive_regulation of Prkcz 2 1 0.04 0.34 0.77
78 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 2 1 0.02 0.34 0.77
79 INT46246 Tpsg1 Regulation of Ache 1 1 0.15 0.06 0.76
80 INT46247 Tpsg1 Regulation of Binding of Ache and 1 1 0.15 0.06 0.76
81 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 1 0.19 0.36 0.75
82 INT106691 Ngf Positive_regulation of SIGMAR1 1 1 0.04 0 0.74
83 INT18447 Binding of Ache and Chat 1 2 0.33 0.33 0.73
84 INT312101 ELANE Regulation of ALOX5AP 1 1 0.21 1.11 0.73
85 INT119314 Ptgs1 Regulation of Gene_expression of Ptger2 1 1 0.01 0.6 0.73
86 INT213726 Binding of Ngfr and Ntrk1 1 1 0.14 0.96 0.72
87 INT43663 Binding of Chrna7 and Rac2 2 1 0.01 0 0.72
88 INT289333 Binding of Ngfr and Rtn4r 1 1 0.03 2.35 0.72
89 INT289332 Binding of Ngfr and Lingo1 1 1 0.04 2.36 0.72
90 INT37874 Positive_regulation of Pag1 Regulation of Nrm 2 1 0.04 0.59 0.71
91 INT159569 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Fos 3 1 0.37 0.4 0.7
92 INT65426 Sigmar1 Regulation of Gpi1 1 1 0.21 0 0.7
93 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 1 0.29 0.32 0.69
94 INT114735 Mtx1 Regulation of Ptgs1 1 1 0.01 0.31 0.69
95 INT289357 Ngfr Positive_regulation of Akt1 1 1 0.03 3.1 0.66
96 INT149684 Negative_regulation of Parp1 Positive_regulation of Oprm1 1 1 0.51 0 0.65
97 INT46892 Positive_regulation of Binding of Pag1 and Nrm 2 1 0.01 0.61 0.63
98 INT46891 Binding of Pag1 and Nrm 2 1 0.01 0.61 0.63
99 INT149681 Parp1 Regulation of Transcription of Oprm1 1 1 0.67 0 0.63
100 INT38905 Ptgfr Regulation of Ptgds 1 1 0.20 0 0.63
101 INT96765 LBR Positive_regulation of Gene_expression of TP53INP2 1 1 0.11 0.5 0.62
102 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 2 1 0.03 0.2 0.62
103 INT55672 Ptgs1 Positive_regulation of Gene_expression of Ik 1 1 0.03 0.75 0.61
104 INT164286 Alox5ap Positive_regulation of Cysltr2 3 1 0.19 1.11 0.61
105 INT164285 Ltc4s Positive_regulation of Cysltr2 1 1 0.20 1.11 0.61
106 INT149682 Parp1 Negative_regulation of Oprm1 1 1 0.47 0 0.6
107 INT164283 Ltb4r Positive_regulation of Ltc4s 1 1 0.37 1.1 0.6
108 INT55919 Binding of Sigmar1 and Ap2s1 1 1 0.02 0.84 0.6
109 INT164284 Ltb4r Positive_regulation of Alox5ap 3 1 0.34 1.1 0.6
110 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 1 0.01 0.51 0.59
111 INT89012 DST Positive_regulation of Insr 1 1 0.01 0.86 0.59
112 INT137247 Slc6a14 Negative_regulation of Ptgs2 1 2 0.19 1.38 0.58
113 INT35398 Fnd3c2 Negative_regulation of Binding of Alox5 and 1 1 0.00 0 0.58
114 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 1 0.19 1.32 0.58
115 INT149683 Parp1 Negative_regulation of Transcription of Oprm1 1 1 0.47 0 0.58
116 INT335432 Ltc4s Regulation of Cysltr2 1 1 0.11 0.38 0.58
117 INT35400 Fnd3c2 Negative_regulation of Binding of Alox5 and Mthfs 1 1 0.00 0 0.58
118 INT335436 Ltc4s Regulation of Gene_expression of Cysltr2 1 1 0.18 0.38 0.58
119 INT2685 S100A6 Positive_regulation of Regulation of Thra 2 1 0.47 0.09 0.58
120 INT2684 S100A6 Regulation of Regulation of Thra 2 1 0.45 0.09 0.58
121 INT73707 Ngf Regulation of Scgb1a1 1 1 0.25 0.61 0.58
122 INT134532 Grin2a Regulation of Ngfr 1 1 0.02 0 0.57
123 INT134528 Grin1 Regulation of Ngfr 1 1 0.03 0 0.57
124 INT134531 Gria1 Regulation of Ngfr 1 1 0.01 0 0.57
125 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 1 0.01 0.49 0.57
126 INT133913 Faf1 Negative_regulation of Regulation of TRPV1 2 1 0.18 0.16 0.56
127 INT95895 Sigmar1 Regulation of Positive_regulation of Npy 2 1 0.18 0 0.55
128 INT97635 ABCF1 Positive_regulation of Localization of CCR1 2 1 0.05 0.51 0.55
129 INT176371 LBR Positive_regulation of IL12A 1 1 0.04 1.22 0.55
130 INT253835 Binding of DST and Fos 1 1 0.02 0 0.55
131 INT133914 Binding of TRPV1 and Faf1 2 1 0.20 0.17 0.55
132 INT176367 LBR Positive_regulation of IFNA1 1 1 0.02 1.22 0.55
133 INT18116 NPC1 Negative_regulation of Binding of NPC1 and Oprd1 1 1 0.13 0 0.54
134 INT155254 Col4a4 Regulation of Rtn4 2 1 0.00 0 0.54
135 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 1 0.05 0.16 0.54
136 INT125086 LPA Positive_regulation of Rtn4 2 1 0.00 0.36 0.54
137 INT161251 Ptgs2 Regulation of Mapk14 1 1 0.16 0.82 0.54
138 INT18115 Binding of NPC1 and Oprd1 1 1 0.11 0 0.54
139 INT76002 Ngf Positive_regulation of Ngfr 1 1 0.05 0.48 0.53
140 INT245558 Runx3 Regulation of Ngfr 1 1 0.06 1 0.53
141 INT21372 Binding of pcp and Sigmar1 2 1 0.01 0 0.53
142 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 1 0.19 0.6 0.52
143 INT54599 Positive_regulation of Ascla2 Positive_regulation of Nrm 2 1 0.00 0.14 0.52
144 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 1 0.00 0.13 0.51
145 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 1 0.00 0.13 0.51
146 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 1 0.00 0.13 0.51
147 INT97636 ABCF1 Positive_regulation of Localization of CXCR1 2 1 0.35 0.45 0.51
148 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 1 0.07 0.38 0.51
149 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 1 0.00 0.13 0.51
150 INT97634 ABCF1 Positive_regulation of Localization of CCL16 2 1 0.11 0.44 0.51
151 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 1 0.00 0.13 0.51
152 INT78590 Nos2 Positive_regulation of PTGS1 1 2 0.00 0.85 0.5
153 INT161227 Binding of Ngfr and Tnf 1 1 0.06 0.41 0.49
154 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 1 0.49 0.44 0.48
155 INT153330 Binding of PTGER3 and Cm9 1 1 0.36 0.15 0.48
156 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 1 0.01 0.62 0.48
157 INT131809 Nfkb1 Positive_regulation of Gene_expression of Ptgs1 1 1 0.12 0.73 0.48
158 INT129551 Sag Negative_regulation of Gene_expression of Ptgs1 1 1 0.08 0.88 0.48
159 INT48102 Positive_regulation of LBR Positive_regulation of Positive_regulation of OR7A5 1 1 0.21 0 0.48
160 INT251163 Gene_expression of Alox5 Positive_regulation of Trpv1 3 1 0.02 0.11 0.48
161 INT312112 ELANE Regulation of Transcription of ALOX5 1 1 0.09 0.82 0.47
162 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 1 0.08 0.15 0.46
163 INT176366 LBR Regulation of IFNA1 1 1 0.04 0.91 0.46
164 INT103026 Ptgis Positive_regulation of Ptgs1 1 1 0.02 0.42 0.46
165 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 1 0.25 0.07 0.46
166 INT103029 Calca Positive_regulation of Positive_regulation of Ptgs1 1 1 0.12 0.41 0.46
167 INT17774 Alb Negative_regulation of Dnase1 1 1 0.02 0 0.46
168 INT99160 Binding of Mpo and Nrm 2 1 0.38 0.92 0.45
169 INT193219 Binding of LTC4S and CYSLTR2 2 2 0.28 2.2 0.44
170 INT69163 Tlr4 Positive_regulation of Ptgs1 1 1 0.02 0.08 0.44
171 INT193217 Binding of PTGER2 and PTGER3 1 2 0.10 1.31 0.43
172 INT12453 Sigmar1 Regulation of Gene_expression of Penk 2 2 0.35 0 0.43
173 INT120295 Ngf Positive_regulation of Positive_regulation of Ngfr 1 1 0.47 0.22 0.43
174 INT158267 Olr1745 Negative_regulation of Alox5 3 1 0.05 0.94 0.43
175 INT229507 Binding of Nefl and Ndel1 1 1 0.09 2.01 0.43
176 INT53470 Acsm3 Regulation of Ptgs1 1 1 0.15 0 0.42
177 INT121378 Fancl Positive_regulation of MIF 1 1 0.01 0.92 0.42
178 INT53469 Negative_regulation of Acsm3 Regulation of Ptgs1 1 1 0.24 0 0.42
179 INT244421 Binding of DST and Ctss 1 1 0.02 0.42 0.41
180 INT209231 Tg(Ngf)47Kma Regulation of Tyro3 1 1 0.03 0 0.41
181 INT53471 Binding of Ptgs1 and Acsm3 1 1 0.17 0 0.41
182 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 1 0.00 0.84 0.41
183 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 1 0.00 0.56 0.41
184 INT203163 LTB4R Regulation of Gene_expression of ALOX5 1 1 0.00 0.98 0.41
185 INT67633 Binding of DST and Gabrd 1 1 0.03 0 0.41
186 INT159571 Trpv1 Positive_regulation of Gene_expression of Alox5 3 1 0.37 0.58 0.4
187 INT312123 ELANE Positive_regulation of ALOX5 1 1 0.09 0.74 0.4
188 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 1 0.00 1.45 0.39
189 INT176361 Positive_regulation of LBR Positive_regulation of Gene_expression of IL18 1 1 0.10 0.84 0.39
190 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 1 0.03 0.67 0.38
191 INT50553 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Tbxa2r 1 1 0.02 1.37 0.38
192 INT73537 Ntf3 Positive_regulation of Ngfr 1 1 0.21 0.1 0.38
193 INT175016 Binding of REN and S100A6 2 2 0.11 1.13 0.37
194 INT28991 Tmpo Positive_regulation of Gene_expression of Pomc 2 1 0.34 0.82 0.37
195 INT158355 Cacna1a Regulation of Alox5 3 1 0.01 0.7 0.37
196 INT73536 Ngf Regulation of Ngfr 1 1 0.22 0.08 0.37
197 INT74244 Ptgs1 Regulation of Positive_regulation of Penk 1 1 0.09 0.19 0.37
198 INT224584 Binding of IL1RN and SIGMAR1 1 1 0.00 0.73 0.36
199 INT6121 Gmcl1 Regulation of Gene_expression of Penk 2 1 0.03 0 0.36
200 INT93694 Binding of Hspa8 and Ptgs1 1 1 0.30 0.79 0.36

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear envelope. They are ordered first by their pain relevance and then by number of times they were reported in nuclear envelope. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
2 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
3 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
4 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
5 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
6 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
7 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
8 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
9 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
10 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53
11 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
12 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17
13 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
14 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
15 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94
16 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
17 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
18 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
19 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
20 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
21 INT276 Regulation of Ache 83 0.62 16.75 25.99
22 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31
23 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
24 INT41230 Gene_expression of Nrm 16 0.67 6.37 21.67
25 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
26 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
27 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
28 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
29 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29
30 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86
31 INT19071 Localization of Ache 66 0.81 5.1 16.27
32 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
33 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
34 INT12837 Binding of SIGMAR1 57 0.48 5.31 15.49
35 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
36 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37
37 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82
38 INT7997 Gene_expression of Ltc4s 51 0.76 34.28 13.8
39 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77
40 INT10499 Positive_regulation of Cenpf 11 0.46 1.27 13.42
41 INT20715 Binding of Sigmar1 45 0.48 4.03 13.17
42 INT3770 Negative_regulation of Nrm 13 0.43 3.55 12.83
43 INT1663 Regulation of Nrm 12 0.55 2.73 12.73
44 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83
45 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77
46 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
47 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56
48 INT787 Localization of Ptgs1 31 0.80 12.36 11.55
49 INT13338 Regulation of Sigmar1 22 0.57 2.91 11.35
50 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85
51 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
52 INT1252 Binding of Ache 46 0.48 9.94 10.25
53 INT17421 Negative_regulation of Alox5 41 0.57 15.23 10.05
54 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
55 INT4808 Gene_expression of LTC4S 37 0.73 18.36 9.62
56 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
57 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
58 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
59 INT23264 Negative_regulation of Positive_regulation of Ptgs1 16 0.39 8.47 8.9
60 INT9889 Gene_expression of Alox5 34 0.63 20.83 8.85
61 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84
62 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78
63 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77
64 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71
65 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56
66 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
67 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
68 INT17221 Localization of TYRO3 2 0.68 0 7.94
69 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78
70 INT60148 Regulation of Sigmar1 20 0.43 7.23 7.76
71 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72
72 INT4807 Localization of LTC4S 23 0.58 6.89 7.59
73 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
74 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
75 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
76 INT39242 Negative_regulation of TMPO 29 0.58 5.15 7.04
77 INT12838 Gene_expression of SIGMAR1 30 0.78 3.52 6.81
78 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
79 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
80 INT16124 Gene_expression of Cenpf 7 0.54 0.69 6.48
81 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
82 INT25130 Positive_regulation of Negative_regulation of Ptgs1 14 0.50 5.07 6.29
83 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14
84 INT17370 Negative_regulation of Negative_regulation of Ptgs1 16 0.22 6.5 6.12
85 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
86 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87
87 INT25242 Positive_regulation of Sigmar1 17 0.66 3.93 5.65
88 INT107619 Gene_expression of PTGER3 42 0.75 15 5.61
89 INT55917 Binding of Sigmar1 26 0.45 12.65 5.58
90 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
91 INT7996 Gene_expression of Ptgds 18 0.64 6.47 5.51
92 INT28164 Regulation of ALOX5 25 0.60 12.76 5.47
93 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4
94 INT28165 Positive_regulation of ALOX5 38 0.47 10.8 5.37
95 INT5978 Positive_regulation of SIGMAR1 13 0.42 0.72 5.35
96 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
97 INT140142 Positive_regulation of Sigmar1 17 0.63 3.78 5.26
98 INT10500 Regulation of Cenpf 3 0.39 0.27 5.26
99 INT39256 Localization of PTGS1 17 0.74 6.62 5.1
100 INT83728 Localization of TMPO 42 0.46 0.46 5.06
101 INT6577 Regulation of Alox5 18 0.47 9.19 5.06
102 INT10606 Localization of Ltc4s 16 0.75 10.14 5.05
103 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03
104 INT16122 Localization of Cenpf 4 0.57 0.61 4.93
105 INT44745 Localization of Nrm 5 0.65 2.04 4.92
106 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
107 INT3476 Phosphorylation of Npc1 7 0.48 0 4.84
108 INT10605 Positive_regulation of Ltc4s 21 0.68 17.22 4.8
109 INT30355 Positive_regulation of Gene_expression of Alox5 10 0.67 14.61 4.69
110 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
111 INT27483 Negative_regulation of Cenpf 3 0.34 0.07 4.68
112 INT15995 Positive_regulation of Alox5 18 0.49 3.94 4.63
113 INT57763 Gene_expression of Lmna 25 0.78 7.11 4.6
114 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
115 INT62500 Transcription of Ptgs1 10 0.56 4.54 4.52
116 INT178751 Positive_regulation of TMPO 51 0.44 1.47 4.41
117 INT64711 Regulation of Ngfr 10 0.45 3.12 4.33
118 INT11946 Transcription of Ache 18 0.69 2.62 4.13
119 INT76227 Binding of NPC1 30 0.41 32.31 4.05
120 INT74365 Positive_regulation of Alox5 19 0.47 11.03 4.04
121 INT121170 Positive_regulation of Gene_expression of Ngfr 10 0.64 9.32 3.94
122 INT64668 Regulation of SIGMAR1 13 0.60 0.54 3.91
123 INT26368 Positive_regulation of S100A6 30 0.45 9.72 3.89
124 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89
125 INT20743 Positive_regulation of Gene_expression of Ltc4s 13 0.60 12.3 3.86
126 INT55907 Binding of Ngfr 13 0.47 5.79 3.75
127 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74
128 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
129 INT44254 Regulation of Gene_expression of ALOX5 12 0.43 7.06 3.65
130 INT21296 Positive_regulation of Cenpf 3 0.03 2.21 3.59
131 INT8778 Regulation of Ache 17 0.62 3.7 3.57
132 INT72290 Localization of Sigmar1 21 0.74 4.35 3.54
133 INT102076 Regulation of DST 15 0.22 10 3.5
134 INT61540 Negative_regulation of Gene_expression of Ngfr 11 0.59 6.36 3.43
135 INT20067 Gene_expression of Cenpf 2 0.32 1.39 3.41
136 INT114571 Gene_expression of Sigmar1 39 0.77 36.78 3.4
137 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36
138 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26
139 INT16159 Regulation of Ltc4s 11 0.38 2.52 3.21
140 INT10476 Binding of ALOX5 26 0.36 7.69 3.2
141 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18
142 INT156676 Gene_expression of Rtn4 14 0.65 5.78 3.16
143 INT155091 Localization of PARP1 15 0.63 13.34 3.15
144 INT195415 Regulation of Gene_expression of ALOX5AP 10 0.45 6.43 3.13
145 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
146 INT77615 Positive_regulation of Negative_regulation of Ptgs1 6 0.50 1.55 3.11
147 INT35448 Negative_regulation of Gene_expression of ALOX5 11 0.57 5.28 3.03
148 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02
149 INT107677 Positive_regulation of Parp1 7 0.45 9.77 3
150 INT35987 Positive_regulation of Tpr 3 0.41 1.47 2.93
151 INT4811 Positive_regulation of Gene_expression of LTC4S 5 0.65 3.29 2.92
152 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9
153 INT200833 Gene_expression of Ndel1 2 0.73 5.56 2.9
154 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
155 INT90402 Positive_regulation of Gene_expression of Ptgs1 13 0.31 4.83 2.88
156 INT107674 Negative_regulation of Parp1 7 0.27 8.91 2.88
157 INT76342 Positive_regulation of Gene_expression of Alox5 9 0.56 5.29 2.87
158 INT48106 Positive_regulation of LBR 11 0.49 5.14 2.86
159 INT17769 Positive_regulation of Dnase1 5 0.69 4.21 2.86
160 INT195421 Positive_regulation of Gene_expression of ALOX5AP 12 0.49 5.17 2.82
161 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79
162 INT13600 Binding of Nrm 4 0.36 2.32 2.79
163 INT11139 Gene_expression of LBR 20 0.75 5.13 2.78
164 INT61541 Positive_regulation of Gene_expression of Ngfr 7 0.53 2.87 2.75
165 INT39243 Regulation of TMPO 20 0.61 5.66 2.67
166 INT29064 Gene_expression of Sigmar1 9 0.77 2.48 2.65
167 INT100743 Regulation of KCNH2 6 0.54 2.37 2.61
168 INT27607 Localization of Ptgs1 7 0.59 3.22 2.6
169 INT86602 Binding of KCNH2 14 0.36 4.65 2.58
170 INT153492 Gene_expression of Gmcl1 44 0.65 15.77 2.56
171 INT34969 Negative_regulation of Binding of Ptgs1 4 0.37 1.55 2.55
172 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
173 INT34905 Positive_regulation of Gene_expression of ALOX5 18 0.50 7.46 2.46
174 INT3475 Regulation of Phosphorylation of Npc1 3 0.36 0 2.45
175 INT70197 Negative_regulation of Positive_regulation of Ptgs1 6 0.24 2.61 2.44
176 INT75225 Transcription of Ngfr 4 0.60 1.95 2.44
177 INT3578 Negative_regulation of TPR 7 0.42 4.18 2.41
178 INT269402 Phosphorylation of TMPO 17 0.32 0.17 2.36
179 INT53476 Positive_regulation of Localization of Ptgs1 6 0.49 2.88 2.35
180 INT35986 Negative_regulation of Tpr 2 0.38 1.67 2.34
181 INT6117 Gene_expression of Gmcl1 4 0.49 2.39 2.33
182 INT129742 Regulation of Positive_regulation of Rtn4 2 0.05 2.51 2.33
183 INT9887 Negative_regulation of Gene_expression of Ptgs1 7 0.42 2.94 2.3
184 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
185 INT16089 Gene_expression of Ltc4s 11 0.77 3.37 2.29
186 INT88241 Positive_regulation of Positive_regulation of Ptgs1 3 0.45 1.71 2.25
187 INT17223 Negative_regulation of Localization of TYRO3 2 0.42 0 2.25
188 INT269372 Positive_regulation of Localization of TMPO 19 0.23 0.25 2.23
189 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18
190 INT163833 Positive_regulation of Localization of PARP1 7 0.28 7.54 2.14
191 INT54823 Phosphorylation of PTGS1 4 0.51 1.61 2.14
192 INT248801 Gene_expression of Mns1 1 0.14 0.32 2.14
193 INT155928 Positive_regulation of Gene_expression of PARP1 13 0.68 6.54 2.1
194 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
195 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1
196 INT26736 Localization of Alox5 7 0.49 3.72 2.09
197 INT108982 Regulation of Gene_expression of Ptgds 6 0.51 1.64 2.07
198 INT44773 Negative_regulation of LBR 6 0.57 2.32 2.03
199 INT156064 Gene_expression of LMNA 50 0.65 13.38 2.01
200 INT229467 Binding of Ndel1 1 0.45 2.71 2
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