GOS:nucleus

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This page displays the top molecular interactions and top single events that were mentioned in the literature for nucleus. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nucleus. They are ordered first by their pain relevance and then by number of times they were reported for nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to nucleus Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 2 1 0.01 28.19 40.6
2 INT259233 Binding of Oprm1 and Flna 1 1 0.03 0.25 25.89
3 INT16531 Ghrh Positive_regulation of Localization of Gh1 2 31 0.64 2.12 14.2
4 INT69886 Ngf Positive_regulation of Calca 1 8 0.76 2.98 12.77
5 INT221180 Binding of OPRM1 and Flna 1 1 0.09 0.22 12.65
6 INT106676 Binding of Trpv1 and Phax 2 18 0.34 4.19 12.36
7 INT166591 Binding of CALCA and DCLK3 2 4 0.30 0.69 12.18
8 INT206768 TP53 Positive_regulation of Ltp 1 2 0.01 5.83 10.21
9 INT26468 Ghrh Positive_regulation of Localization of Gh 2 21 0.37 3.26 9.21
10 INT180785 Gdnf Positive_regulation of Calca 1 1 0.23 1.96 8.04
11 INT11250 Cck Positive_regulation of Gene_expression of Fos 3 14 0.78 0.08 7.29
12 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 2 1 0.10 3.92 7.2
13 INT254001 Binding of Cxcr4 and Mif 1 1 0.52 14.17 7.18
14 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 1 0.10 2.91 6.54
15 INT251170 Clu Positive_regulation of Trpv1 1 1 0.28 2.61 6.49
16 INT169218 Binding of EGFR and Coc 1 1 0.06 2.8 5.85
17 INT338167 Binding of CDKN2A and MC1R 1 1 0.42 6.14 5.76
18 INT142177 Calca Positive_regulation of Gene_expression of Igf1 1 8 0.78 3.57 5.71
19 INT296275 Binding of Dlg4 and Kcnip3 1 1 0.39 3.58 5.6
20 INT20133 Trh Positive_regulation of Localization of Prl 1 23 0.78 2.04 5.44
21 INT170447 Binding of Pax3 and Spr 2 1 0.01 0.1 5.37
22 INT126335 Binding of Pax3 and Tac1 1 6 0.07 6.22 5.27
23 INT9546 Binding of Adarb1 and Penk 2 5 0.03 0 5.1
24 INT69888 Ngf Positive_regulation of Localization of Calca 1 4 0.52 0.51 4.95
25 INT102122 Binding of Calca and RT1-M4 1 7 0.29 5.83 4.94
26 INT11599 Calca Positive_regulation of Npr1 1 5 0.19 0.3 4.8
27 INT166590 Binding of RAMP1 and DCLK3 1 2 0.37 0.39 4.8
28 INT10844 Ghrh Regulation of Gh 2 13 0.13 4.77 4.71
29 INT24742 Binding of Calca and Vip 1 1 0.37 0.18 4.68
30 INT164362 Binding of NLRP1 and VTA1 1 1 0.15 2.37 4.67
31 INT182124 Binding of IRF6 and TLR4 1 14 0.10 16.11 4.65
32 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 1 0.10 1.36 4.52
33 INT128295 IL1B Positive_regulation of Insr 1 1 0.11 1.36 4.5
34 INT186566 Hpcl1 Positive_regulation of Fos 3 1 0.17 0.38 4.49
35 INT1390 Trh Positive_regulation of Prl 1 14 0.67 4.42 4.39
36 INT7022 Drd1a Positive_regulation of Npr1 2 6 0.05 0.26 4.32
37 INT1392 Trh Regulation of Prl 1 15 0.29 2.47 4.29
38 INT259209 Binding of Glul and Flna 1 1 0.03 0 4.2
39 INT143270 Binding of Cnr1 and Gprasp1 1 4 0.54 0.64 4.18
40 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 3 0.30 0.91 4.18
41 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 1 0.66 2.96 4.15
42 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 1 0.02 0 4.15
43 INT64756 oh Negative_regulation of Gpi1 1 1 0.03 0 4.09
44 INT16221 Ghrh Positive_regulation of Gh 2 8 0.21 1.89 4.08
45 INT29240 Binding of POMC and YY1 1 5 0.40 0.17 4.06
46 INT11248 Gh Positive_regulation of Ghrh 2 2 0.26 0.09 4.04
47 INT13969 Binding of Calca and Sst 1 3 0.32 0.6 4.02
48 INT73539 Binding of Ngf and Ngfr 1 5 0.45 3.99 4
49 INT138961 Dbi Positive_regulation of Chkb 1 1 0.00 3.05 3.99
50 INT138959 Dbi Positive_regulation of Penk 1 1 0.01 3.05 3.99
51 INT200322 Binding of Rest and Sp3 3 1 0.39 2.93 3.98
52 INT32911 Binding of Insrr and Rbm39 2 2 0.00 0 3.95
53 INT13966 Calca Positive_regulation of Localization of Sst 1 5 0.49 0.75 3.91
54 INT136514 Binding of Grm1 and Grm5 2 4 0.12 1.8 3.9
55 INT61359 TNF Positive_regulation of NFKB1 1 11 0.63 6.66 3.89
56 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 6 2 0.27 0.43 3.88
57 INT130625 Prkcg Regulation of Prkaca 4 1 0.23 1.32 3.87
58 INT317511 Ppp1r9b Regulation of Oprm1 1 3 0.27 0.33 3.85
59 INT317517 Binding of Nos1 and Oprm1 1 1 0.17 0.22 3.85
60 INT143946 Binding of Pebp1 and Mastl 1 1 0.00 2.04 3.82
61 INT220623 Binding of Stat1 and Bace1 2 11 0.25 10.33 3.81
62 INT11252 Cck Positive_regulation of Fos 3 6 0.78 0 3.79
63 INT180813 Ngf Positive_regulation of Sorbs1 1 1 0.04 2.09 3.79
64 INT134284 Binding of OPRM1 and PLD2 1 1 0.52 0 3.72
65 INT85541 Ngf Positive_regulation of Gene_expression of Calca 1 2 0.55 1.84 3.71
66 INT104977 MITF Regulation of Gene_expression of MC1R 1 1 0.69 0.91 3.71
67 INT107331 Binding of PPBP and Adarb1 2 1 0.01 0 3.67
68 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 1 0.00 1.25 3.63
69 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 5 1 0.47 0.72 3.63
70 INT140011 Avp Positive_regulation of Dbi 1 2 0.07 0.93 3.61
71 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 2 1 0.34 1.96 3.6
72 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 1 0.72 0.92 3.52
73 INT17317 Binding of Jun and Fos 5 7 0.42 1.03 3.5
74 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 1 0.27 0.17 3.48
75 INT24710 Binding of Calca and SUB1P1 1 1 0.01 2.09 3.48
76 INT180984 IRF6 Positive_regulation of Localization of IL8 1 7 0.11 2.13 3.47
77 INT302118 Binding of Oprm1 and Ppp1r9b 1 2 0.24 0.26 3.45
78 INT334928 Binding of pr and Aes 3 1 0.00 1.49 3.38
79 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 1 0.00 0.99 3.34
80 INT128292 Nts Positive_regulation of Insr 1 1 0.03 0.99 3.34
81 INT128291 Vom1r68 Positive_regulation of Insr 1 1 0.00 0.99 3.33
82 INT215943 Binding of Mmp14 and Timp2 1 1 0.21 1.59 3.33
83 INT128294 Aldh1a1 Positive_regulation of Insr 1 1 0.00 0.99 3.33
84 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 1 0.41 0 3.31
85 INT276678 Nkx1-1 Regulation of Nav1 1 1 0.15 0.88 3.31
86 INT276676 Prkcg Regulation of Nav1 2 1 0.30 0.82 3.29
87 INT182704 Binding of NPFF and TP53INP2 1 1 0.01 0.73 3.28
88 INT48162 RIMS3 Regulation of Localization of LTC4S 1 1 0.10 2.14 3.25
89 INT108471 Binding of CALCA and PNOC 1 1 0.29 0.64 3.25
90 INT69823 Binding of GHR and RYBP 2 1 0.01 0 3.23
91 INT74159 Ngf Regulation of Gene_expression of Calca 1 2 0.60 1.66 3.22
92 INT108810 Esr1 Positive_regulation of Binding of Oprm1 and 2 1 0.51 1.79 3.22
93 INT29657 Binding of Calca and Calcb 1 1 0.26 0 3.16
94 INT275850 Binding of NDUFAB1 and SNCA 1 1 0.00 3.78 3.16
95 INT128513 Pnoc Regulation of Adarb1 2 1 0.01 0.92 3.14
96 INT202959 Binding of BAG3 and MCRS1 1 1 0.11 7.46 3.14
97 INT289979 Binding of Helt and Negative_regulation of Maoa 1 1 0.00 0.17 3.14
98 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 3 1 0.43 0.4 3.13
99 INT85042 Binding of CCT6A and MAX 1 1 0.00 0 3.13
100 INT94204 NCOR2 Regulation of Gene_expression of SP5 3 1 0.02 2.15 3.12
101 INT161164 Prkcg Regulation of Phosphorylation of Creb1 6 3 0.41 0.62 3.11
102 INT101407 Binding of Grin1 and Spr 1 1 0.14 0.86 3.09
103 INT309150 Edc4 Positive_regulation of Creb1 6 1 0.03 3.46 3.09
104 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 3 1 0.07 0.94 3.08
105 INT26677 Penk Regulation of Localization of Trh 1 5 0.50 0 3.05
106 INT317563 Binding of Hint1 and Oprm1 2 1 0.20 0.25 3.03
107 INT106837 Binding of Oprm1 and Arrb2 1 3 0.32 0.83 3.01
108 INT37162 Binding of Calca and Cckar 1 1 0.04 0.55 3.01
109 INT123451 Binding of YY1 and Adra2a 1 1 0.37 0 2.98
110 INT118158 Binding of Prkca and Prkcz 2 1 0.07 1.14 2.98
111 INT113234 Binding of Pax3 and Tacr1 1 3 0.12 1.54 2.93
112 INT100835 Binding of Calca and Akap12 1 1 0.07 0.41 2.92
113 INT166592 Binding of CALCA and RAMP1 1 2 0.35 0.33 2.91
114 INT73821 CALCA Positive_regulation of Localization of IL8 1 1 0.25 2.37 2.91
115 INT130721 Binding of IL1B and IL1RN 1 6 0.05 5.29 2.85
116 INT114126 Binding of APLNR and OPRL1 1 1 0.01 0.47 2.85
117 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 4 1 0.00 1.86 2.85
118 INT194409 Binding of CALCA and IGKV1D-8 1 1 0.15 0 2.84
119 INT32656 Pomc Positive_regulation of Rbm39 2 1 0.08 0.42 2.84
120 INT351349 Prkcg Positive_regulation of Binding of Lpar1 and 2 1 0.15 2 2.82
121 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 3 2 0.02 0.44 2.79
122 INT169134 Binding of Calca and Trpa1 1 1 0.37 3.37 2.79
123 INT91649 Binding of Lbp and SPECC1 1 1 0.12 2.88 2.78
124 INT190167 Binding of JUN and MMP12 1 1 0.26 0.82 2.76
125 INT137230 Trh Regulation of Gene_expression of Oprd1 1 1 0.01 1.62 2.75
126 INT317551 Binding of Akt1 and Oprm1 2 1 0.19 0.21 2.74
127 INT127621 Bst1 Regulation of Positive_regulation of Fos 3 1 0.26 0 2.73
128 INT140347 Binding of ATP1A2 and Cacna1a 1 1 0.11 2.88 2.73
129 INT226118 Ghrl Regulation of Prkag1 1 1 0.08 0.72 2.72
130 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 2 1 0.76 3.07 2.71
131 INT180779 Bdnf Regulation of Calca 1 1 0.09 0.23 2.71
132 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 1 0.49 0.67 2.69
133 INT259231 Binding of Oprm1 and Ppp1r9b 1 1 0.01 0 2.67
134 INT91350 Binding of Pla2g4a and RYBP 2 1 0.00 1.15 2.65
135 INT70946 Penk Positive_regulation of Hpse 2 1 0.34 0 2.65
136 INT150457 Binding of Sort1 and Prss12 1 3 0.21 1.36 2.64
137 INT124547 Trib3 Regulation of Regulation of Th 4 1 0.02 0.79 2.64
138 INT259198 Oprm1 Negative_regulation of Binding of Oprm1 and Flna 1 1 0.00 0 2.64
139 INT259214 Oprm1 Negative_regulation of Binding of Flna and Flna 1 1 0.01 0 2.64
140 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 2 1 0.38 0.86 2.63
141 INT251150 Binding of Nos1 and Dlg2 1 1 0.30 1.98 2.62
142 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 2 0.46 0.75 2.61
143 INT53648 Acot1 Positive_regulation of Localization of Calca 1 2 0.23 0 2.61
144 INT121742 Prkcg Positive_regulation of Ephb1 2 3 0.49 0.99 2.6
145 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 2 1 0.06 0.5 2.6
146 INT152501 Binding of Tnf and Tnfrsf1a 1 4 0.31 3 2.58
147 INT67905 Binding of Spn and Fosl1 1 1 0.24 2.1 2.54
148 INT57624 Calca Regulation of Positive_regulation of Trh 2 1 0.50 0 2.53
149 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 1 0.78 0.16 2.53
150 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 3 1 0.12 0 2.53
151 INT253988 Binding of Cd74 and Mif 1 1 0.36 6.57 2.52
152 INT356289 Binding of Egfr and Egf 2 1 0.13 3.02 2.52
153 INT107812 Nppa Positive_regulation of Localization of Sst 1 1 0.48 0.54 2.51
154 INT48526 Binding of Calca and Penk 1 1 0.24 1.03 2.51
155 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 1 0.09 5.43 2.51
156 INT317528 Ppp1r9b Regulation of Grin1 1 1 0.18 0.2 2.48
157 INT314141 Binding of Tacr3 and SFTPA1 1 1 0.00 3.02 2.48
158 INT20411 Ghrh Positive_regulation of Gh1 2 6 0.56 0.62 2.47
159 INT92182 Mir702 Negative_regulation of Adk 1 1 0.07 1.29 2.47
160 INT113715 Msh3 Positive_regulation of tf 1 1 0.11 0 2.47
161 INT170038 Gtf3a Regulation of Gene_expression of DRGX 3 1 0.00 1.36 2.46
162 INT14687 Binding of Penk and Ppt1 2 1 0.41 0 2.46
163 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 2 1 0.07 1.72 2.46
164 INT170037 Ngf Regulation of Gene_expression of DRGX 1 1 0.01 1.37 2.46
165 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 1 0.54 0.85 2.44
166 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 1 0.01 0 2.44
167 INT147659 Prkce Positive_regulation of TRPV1 1 1 0.04 1.42 2.43
168 INT143272 Binding of CNR1 and Gprasp1 1 1 0.01 0.17 2.42
169 INT37873 Pag1 Regulation of Nrm 1 2 0.04 1.1 2.41
170 INT136129 Calca Positive_regulation of ATP8A2 1 1 0.38 0.89 2.4
171 INT317526 Binding of Hint1 and Gipc1 2 1 0.00 0.25 2.38
172 INT81657 Binding of CPOX and PTGS1 1 5 0.15 1.9 2.37
173 INT74840 Binding of Cacna1a and Cacna1a 2 5 0.00 4.24 2.36
174 INT153728 RYBP Positive_regulation of Gpt 1 3 0.03 2.01 2.36
175 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 3 0.23 0 2.35
176 INT121746 Prkaca Positive_regulation of Ephb1 2 2 0.23 0.92 2.35
177 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 1 0.19 3.22 2.35
178 INT284860 Binding of Pdzd2 and Nav1 1 9 0.29 2.33 2.34
179 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 2 1 0.37 1.4 2.34
180 INT139723 PROC Positive_regulation of MAPK8 1 1 0.01 2.98 2.33
181 INT249013 Gabrg1 Negative_regulation of Per2 2 1 0.34 0.07 2.31
182 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 1 0.00 0.08 2.31
183 INT54489 Binding of Jun and Rabep2 2 4 0.16 1.48 2.3
184 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 2 1 0.43 1.24 2.3
185 INT13967 Calca Positive_regulation of Sst 1 1 0.45 0 2.3
186 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 2 1 0.23 1.41 2.3
187 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 1 0.69 0.73 2.29
188 INT152901 TRPV1 Regulation of Localization of CALCA 1 1 0.44 0.73 2.29
189 INT321474 Binding of Slc6a2 and Ubqln1 1 1 0.00 0.8 2.27
190 INT156622 Umod Regulation of Phosphorylation of Creb1 4 1 0.05 0.33 2.27
191 INT321477 Binding of Ubqln1 and Flvcr2 1 1 0.00 0.81 2.26
192 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 1 0.01 0 2.26
193 INT7367 Ghrh Regulation of Localization of Gh1 2 5 0.49 1.55 2.25
194 INT85251 Chi3l1 Positive_regulation of Casp3 1 1 0.01 0 2.25
195 INT275398 Binding of ITIH4 and Htatsf1 2 1 0.02 5.05 2.24
196 INT251164 Binding of Clu and Trpv1 1 1 0.19 0.44 2.23
197 INT114432 Oprl1 Positive_regulation of Akt1 2 1 0.18 0.08 2.2
198 INT279361 Binding of TNF and KLF1 1 4 0.00 3.72 2.19
199 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 3 2 0.12 0 2.19
200 INT69887 Ngf Regulation of Calca 1 2 0.49 0.1 2.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for nucleus. They are ordered first by their pain relevance and then by number of times they were reported in nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
3 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
4 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
5 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
6 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
7 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
8 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
9 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
10 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
11 INT876 Localization of Gh1 843 0.80 67.75 340.82
12 INT2649 Regulation of Calca 433 0.62 146.05 330.95
13 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
14 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
15 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
16 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
17 INT1893 Localization of Gh 1041 0.79 340.23 256.58
18 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
19 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
20 INT626 Localization of CALCA 289 0.81 125.39 221.15
21 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
22 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
23 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
24 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
25 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
26 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
27 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
28 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
29 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
30 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
31 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
32 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
33 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
34 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
35 INT2541 Binding of Calca 200 0.48 67.14 134.62
36 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
37 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
38 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
39 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
40 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
41 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
42 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73
43 INT5008 Localization of Calca 204 0.81 80.35 125.16
44 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
45 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
46 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92
47 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
48 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
49 INT1530 Regulation of Gh 382 0.61 115.96 112.47
50 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
51 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
52 INT7327 Regulation of Th 164 0.62 29.67 110.14
53 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
54 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
55 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
56 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
57 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
58 INT5587 Regulation of Fos 191 0.62 40.81 99.7
59 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
60 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
61 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
62 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
63 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
64 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
65 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
66 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
67 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
68 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
69 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
70 INT6437 Binding of YY1 154 0.47 26.3 90.46
71 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28
72 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
73 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57
74 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
75 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
76 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
77 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
78 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
79 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
80 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
81 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92
82 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
83 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
84 INT5617 Localization of Nppa 266 0.81 83.51 83.89
85 INT339 Regulation of Trh 156 0.62 39.27 83.55
86 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
87 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
88 INT8534 Localization of Pax3 85 0.59 28.71 82.82
89 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
90 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
91 INT403 Localization of Trh 241 0.81 28.55 81.45
92 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
93 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
94 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
95 INT24958 Gene_expression of Nkx1-1 106 0.74 51.29 76.88
96 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
97 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
98 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
99 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
100 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
101 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
102 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
103 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
104 INT1376 Binding of Trh 121 0.48 20 69.86
105 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83
106 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
107 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
108 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
109 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
110 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
111 INT4637 Binding of Adarb1 132 0.41 14.48 67.76
112 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63
113 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
114 INT1603 Negative_regulation of Rtcd1 131 0.51 29.99 66.66
115 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44
116 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
117 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
118 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
119 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
120 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
121 INT6761 Binding of CALCA 100 0.48 26.71 62.05
122 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
123 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89
124 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
125 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
126 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
127 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
128 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
129 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
130 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
131 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
132 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
133 INT13938 Positive_regulation of Nkx1-1 64 0.68 30.83 58.75
134 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62
135 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
136 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
137 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52
138 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
139 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
140 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
141 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
142 INT1782 Regulation of Gh1 125 0.62 22 55.74
143 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
144 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
145 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
146 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
147 INT5770 Binding of Rbm39 88 0.41 13.23 55.5
148 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
149 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
150 INT12717 Binding of Pck1 85 0.47 12.49 54.81
151 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
152 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
153 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
154 INT4891 Transcription of Calca 81 0.72 35.27 53.75
155 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
156 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64
157 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
158 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
159 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
160 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
161 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
162 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
163 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
164 INT52264 Gene_expression of IK 180 0.77 90.87 51.87
165 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
166 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
167 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
168 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
169 INT221172 Binding of Flna 32 0.42 1.37 51.59
170 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
171 INT122041 Binding of Ppara 308 0.48 189.17 51.48
172 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
173 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
174 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
175 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03
176 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
177 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
178 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
179 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5
180 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
181 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
182 INT55671 Gene_expression of Ik 151 0.27 80.1 48.49
183 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47
184 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
185 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53
186 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06
187 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
188 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
189 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
190 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
191 INT4656 Localization of RYBP 49 0.77 5.28 46.21
192 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2
193 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
194 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
195 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
196 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
197 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
198 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
199 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
200 INT989 Negative_regulation of Trh 90 0.59 15.45 43.63
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