GOS:plasma membrane

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This page displays the top molecular interactions and top single events that were mentioned in the literature for plasma membrane. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported for plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to plasma membrane Documents TM Confidence Disease Relevance Pain Relevance
1 INT66535 Binding of Pnoc and Oprl1 1 43 0.54 5.93 32.4
2 INT259233 Binding of Oprm1 and Flna 2 1 0.03 0.25 25.89
3 INT69872 Binding of MC1R and POMC 2 52 0.54 8.87 18.3
4 INT16531 Ghrh Positive_regulation of Localization of Gh1 2 31 0.64 2.12 14.2
5 INT221180 Binding of OPRM1 and Flna 2 1 0.09 0.22 12.65
6 INT106676 Binding of Trpv1 and Phax 1 18 0.34 4.19 12.36
7 INT145775 Ngf Positive_regulation of Trpv1 1 11 0.72 7.71 11.25
8 INT10268 Binding of PDYN and POMC 1 11 0.39 0.08 10.36
9 INT68514 Pnoc Positive_regulation of Oprl1 1 10 0.59 3.56 9.57
10 INT77646 Binding of Ngf and Ntrk1 1 23 0.40 7.85 9.26
11 INT26468 Ghrh Positive_regulation of Localization of Gh 1 21 0.37 3.26 9.21
12 INT65724 Binding of Pnoc and Oprl1 1 8 0.33 2.94 8.82
13 INT21276 Binding of Oprd1 and Penk 1 9 0.54 1.14 8.28
14 INT51205 Binding of OPRK1 and PDYN 2 7 0.00 2.01 7.8
15 INT149117 Binding of CD80 and CTLA4 2 31 0.52 12.7 7.73
16 INT106559 Binding of Bdnf and Ntrk2 2 23 0.43 11.09 7.33
17 INT259228 Binding of Oprm1 and Glul 1 1 0.00 0.08 7.22
18 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 2 1 0.10 3.92 7.2
19 INT254001 Binding of Cxcr4 and Mif 1 1 0.52 14.17 7.18
20 INT188692 Binding of Cd40 and Cd40lg 2 32 0.34 22.95 6.62
21 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 1 0.10 2.91 6.54
22 INT251170 Clu Positive_regulation of Trpv1 1 1 0.28 2.61 6.49
23 INT131249 Binding of Bdnf and Ntrk2 3 11 0.41 4 6.25
24 INT84921 Binding of NGF and NTRK1 1 13 0.50 6.39 6.1
25 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 1 8 0.74 4.31 6.1
26 INT155484 Binding of CD86 and CTLA4 2 15 0.52 8.85 6.09
27 INT176477 Binding of CXCR3 and CXCL10 1 14 0.25 10.61 5.87
28 INT169218 Binding of EGFR and Coc 2 1 0.06 2.8 5.85
29 INT269444 Binding of RAB5A and HHIP 2 1 0.04 0 5.79
30 INT338167 Binding of CDKN2A and MC1R 2 1 0.42 6.14 5.76
31 INT179502 Binding of Cd14 and Tlr4 3 29 0.39 13.77 5.73
32 INT140935 Binding of Cd40lg and Cd40 3 1 0.30 6.34 5.61
33 INT95068 Tlr4 Positive_regulation of IL1B 1 1 0.03 4.54 5.6
34 INT296275 Binding of Dlg4 and Kcnip3 2 1 0.39 3.58 5.6
35 INT20133 Trh Positive_regulation of Localization of Prl 1 23 0.78 2.04 5.44
36 INT126335 Binding of Pax3 and Tac1 1 6 0.07 6.22 5.27
37 INT88279 Ngf Positive_regulation of Ntrk1 1 5 0.76 3.06 5.23
38 INT11599 Calca Positive_regulation of Npr1 1 5 0.19 0.3 4.8
39 INT166590 Binding of RAMP1 and DCLK3 3 2 0.37 0.39 4.8
40 INT211710 Binding of Mc1r and a 1 7 0.44 0.37 4.78
41 INT44716 Binding of ABL2 and PDYN 1 2 0.40 0.66 4.77
42 INT10844 Ghrh Regulation of Gh 1 13 0.13 4.77 4.71
43 INT125407 Binding of OPRL1 and PTPRM 1 1 0.03 0.72 4.67
44 INT182124 Binding of IRF6 and TLR4 2 14 0.10 16.11 4.65
45 INT139706 Tnf Positive_regulation of Ltp 2 1 0.03 2.61 4.63
46 INT351352 Binding of Trpv1 and Lpar1 2 1 0.21 5.86 4.62
47 INT296484 Binding of Gria2 and GRIP1 2 1 0.04 4.52 4.59
48 INT34444 Binding of Oprl1 and Ptprg 1 4 0.03 0.18 4.58
49 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 2 1 0.10 1.36 4.52
50 INT128295 IL1B Positive_regulation of Insr 2 1 0.11 1.36 4.5
51 INT1390 Trh Positive_regulation of Prl 1 14 0.67 4.42 4.39
52 INT64480 Binding of OPRL1 and PNOC 1 2 0.33 0.23 4.38
53 INT180774 Gdnf Positive_regulation of Trpv1 1 1 0.33 2.43 4.37
54 INT111758 Binding of Drd2 and Insrr 2 1 0.01 0.94 4.33
55 INT7022 Drd1a Positive_regulation of Npr1 3 6 0.05 0.26 4.32
56 INT1392 Trh Regulation of Prl 1 15 0.29 2.47 4.29
57 INT40114 Binding of OPRD1 and Oprm1 2 2 0.00 0 4.29
58 INT113223 POMC Regulation of MC1R 2 6 0.68 0.39 4.24
59 INT259209 Binding of Glul and Flna 1 1 0.03 0 4.2
60 INT143270 Binding of Cnr1 and Gprasp1 1 4 0.54 0.64 4.18
61 INT103724 Oprd1 Positive_regulation of Gtpbp4 1 3 0.30 0.91 4.18
62 INT182194 Binding of IL8 and CXCR2 1 10 0.56 7.14 4.16
63 INT259230 Negative_regulation of Binding of Oprm1 and Flna 2 1 0.02 0 4.15
64 INT64756 oh Negative_regulation of Gpi1 1 1 0.03 0 4.09
65 INT16221 Ghrh Positive_regulation of Gh 1 8 0.21 1.89 4.08
66 INT29240 Binding of POMC and YY1 1 5 0.40 0.17 4.06
67 INT34220 Binding of POMC and Oprl1 1 4 0.01 0.25 4.05
68 INT11248 Gh Positive_regulation of Ghrh 1 2 0.26 0.09 4.04
69 INT101942 Binding of CD40 and CD40LG 3 16 0.23 15.24 4.01
70 INT73539 Binding of Ngf and Ngfr 2 5 0.45 3.99 4
71 INT138961 Dbi Positive_regulation of Chkb 1 1 0.00 3.05 3.99
72 INT138959 Dbi Positive_regulation of Penk 1 1 0.01 3.05 3.99
73 INT127128 Binding of CNR1 and CNR2 2 8 0.39 3.98 3.97
74 INT82023 Binding of Ntrk1 and Ngf 1 5 0.53 3.48 3.92
75 INT136514 Binding of Grm1 and Grm5 3 4 0.12 1.8 3.9
76 INT61359 TNF Positive_regulation of NFKB1 1 11 0.63 6.66 3.89
77 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 2 0.27 0.43 3.88
78 INT130625 Prkcg Regulation of Prkaca 4 1 0.23 1.32 3.87
79 INT317511 Ppp1r9b Regulation of Oprm1 2 3 0.27 0.33 3.85
80 INT317517 Binding of Nos1 and Oprm1 3 1 0.17 0.22 3.85
81 INT249566 Binding of Oprd1 and Psmd1 1 1 0.01 0.82 3.8
82 INT122349 Ngf Regulation of Trpv1 1 3 0.64 1.55 3.79
83 INT180813 Ngf Positive_regulation of Sorbs1 1 1 0.04 2.09 3.79
84 INT136525 Binding of Prokr1 and Trpv1 3 1 0.39 2.9 3.76
85 INT141254 Ngf Regulation of Transcription of Trpv1 1 1 0.53 1.37 3.74
86 INT134284 Binding of OPRM1 and PLD2 2 1 0.52 0 3.72
87 INT104977 MITF Regulation of Gene_expression of MC1R 2 1 0.69 0.91 3.71
88 INT181455 Binding of Ccr5 and Ccl5 1 11 0.39 12.13 3.66
89 INT34534 Binding of Penk and Oprl1 1 4 0.37 0 3.64
90 INT71069 Oprl1 Regulation of Gene_expression of Tac4 1 1 0.03 0.13 3.64
91 INT64883 Ptger2 Positive_regulation of Ina 1 1 0.03 1.26 3.64
92 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 1 0.00 1.25 3.63
93 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 2 1 0.47 0.72 3.63
94 INT140011 Avp Positive_regulation of Dbi 1 2 0.07 0.93 3.61
95 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 2 1 0.34 1.96 3.6
96 INT18026 Binding of Oprd1 and Oprm1 1 4 0.40 0.83 3.53
97 INT121651 Binding of CXCL12 and CXCR4 1 13 0.48 17.61 3.52
98 INT85743 Pdyn Positive_regulation of Oprk1 2 3 0.32 2.12 3.52
99 INT158770 Binding of Trpv1 and Trpa1 1 5 0.34 2.07 3.5
100 INT302118 Binding of Oprm1 and Ppp1r9b 2 2 0.24 0.26 3.45
101 INT195931 Binding of OPRM1 and Trpv1 3 1 0.07 0.87 3.43
102 INT152035 Binding of HLA-A and MRAP 2 2 0.31 6.95 3.4
103 INT212658 KCNA1 Positive_regulation of Cort 1 1 0.00 2.58 3.36
104 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 2 1 0.00 0.99 3.34
105 INT128292 Nts Positive_regulation of Insr 2 1 0.03 0.99 3.34
106 INT128291 Vom1r68 Positive_regulation of Insr 2 1 0.00 0.99 3.33
107 INT128294 Aldh1a1 Positive_regulation of Insr 2 1 0.00 0.99 3.33
108 INT137918 Oprm1 Positive_regulation of Pdgfrb 3 1 0.41 0 3.31
109 INT276676 Prkcg Regulation of Nav1 2 1 0.30 0.82 3.29
110 INT189488 Binding of Ccr1 and Ccl5 1 8 0.40 9.26 3.27
111 INT354207 Igfbp7 Positive_regulation of Accn3 1 1 0.52 6.55 3.24
112 INT69823 Binding of GHR and RYBP 1 1 0.01 0 3.23
113 INT194647 Binding of CD28 and CD80 3 15 0.40 4.9 3.22
114 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 3 2 0.66 5.22 3.22
115 INT108810 Esr1 Positive_regulation of Binding of Oprm1 and 2 1 0.51 1.79 3.22
116 INT270949 Binding of Slc6a3 and Cpe 2 1 0.28 0.25 3.19
117 INT166134 Binding of Cxcl12 and Cxcr4 2 3 0.49 5.69 3.17
118 INT275850 Binding of NDUFAB1 and SNCA 1 1 0.00 3.78 3.16
119 INT251146 Binding of Grin1 and Dlg2 2 1 0.36 1.95 3.16
120 INT202959 Binding of BAG3 and MCRS1 1 1 0.11 7.46 3.14
121 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 4 1 0.43 0.4 3.13
122 INT186126 Binding of CD28 and CTLA4 3 9 0.52 4.13 3.12
123 INT171974 Binding of Tnfrsf11a and Tnfsf11 1 14 0.35 13.11 3.11
124 INT122780 Ngf Regulation of Gene_expression of Trpv1 1 4 0.65 3.74 3.11
125 INT161164 Prkcg Regulation of Phosphorylation of Creb1 2 3 0.41 0.62 3.11
126 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 2 3 0.00 0.63 3.1
127 INT81708 POMC Regulation of Gene_expression of ITGAM 1 1 0.53 0.72 3.1
128 INT158752 Binding of TRPV1 and Rvm 1 1 0.05 1.6 3.1
129 INT101408 Binding of Grin1 and Olr1469 2 1 0.03 0.86 3.1
130 INT101407 Binding of Grin1 and Spr 1 1 0.14 0.86 3.09
131 INT208572 Binding of IL8 and CXCR1 1 6 0.33 5.2 3.08
132 INT158751 Binding of TRPV1 and Pag1 3 1 0.03 1.59 3.08
133 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 2 1 0.07 0.94 3.08
134 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 1 2 0.67 2.13 3.06
135 INT26677 Penk Regulation of Localization of Trh 1 5 0.50 0 3.05
136 INT317563 Binding of Hint1 and Oprm1 2 1 0.20 0.25 3.03
137 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 2 5 0.34 0 3.01
138 INT102284 Binding of Grin1 and Grin2a 2 5 0.27 1.79 3.01
139 INT106837 Binding of Oprm1 and Arrb2 2 3 0.32 0.83 3.01
140 INT40660 Pdyn Positive_regulation of Localization of Prl 2 1 0.27 0 3.01
141 INT37162 Binding of Calca and Cckar 1 1 0.04 0.55 3.01
142 INT182635 Binding of CCR5 and CCL5 1 2 0.09 4.19 3
143 INT123451 Binding of YY1 and Adra2a 3 1 0.37 0 2.98
144 INT118158 Binding of Prkca and Prkcz 4 1 0.07 1.14 2.98
145 INT202965 Binding of STC2 and BAG3 1 1 0.02 7.86 2.96
146 INT324927 Syt17 Positive_regulation of Bdkrb1 1 1 0.04 4.29 2.96
147 INT113234 Binding of Pax3 and Tacr1 1 3 0.12 1.54 2.93
148 INT100835 Binding of Calca and Akap12 2 1 0.07 0.41 2.92
149 INT41152 Binding of Penk and Slc3a1 1 3 0.12 0.11 2.91
150 INT166592 Binding of CALCA and RAMP1 3 2 0.35 0.33 2.91
151 INT42728 Binding of PRLR and Cpe 1 1 0.00 0 2.91
152 INT318996 Binding of CCR3 and CCL5 2 1 0.07 3.39 2.9
153 INT156381 Binding of Grin1 and Dlg4 2 1 0.39 0.86 2.9
154 INT111757 Positive_regulation of Binding of Drd2 and Insrr 2 1 0.02 0.64 2.89
155 INT319003 Binding of CCR1 and CCL5 3 1 0.08 3.38 2.89
156 INT264929 Binding of Cnr1 and Gnaz 2 1 0.18 1.71 2.89
157 INT221746 Ngf Positive_regulation of Ntrk1 1 1 0.02 0.92 2.88
158 INT130721 Binding of IL1B and IL1RN 1 6 0.05 5.29 2.85
159 INT114126 Binding of APLNR and OPRL1 2 1 0.01 0.47 2.85
160 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 2 1 0.00 1.86 2.85
161 INT206764 Binding of AQP4 and Nqo1 2 8 0.05 13.45 2.84
162 INT106560 Binding of Ntf3 and Ntrk2 2 3 0.14 2.47 2.84
163 INT107723 POMC Positive_regulation of MC1R 2 7 0.68 0.71 2.82
164 INT351349 Prkcg Positive_regulation of Binding of Lpar1 and 3 1 0.15 2 2.82
165 INT175329 Binding of ICAM1 and ITGAL 2 14 0.18 10.06 2.81
166 INT220062 Binding of NGF and TNFRSF1B 1 1 0.10 2.21 2.81
167 INT170367 Binding of Grin1 and Grin2a 2 5 0.23 1.72 2.79
168 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 2 0.02 0.44 2.79
169 INT186128 Binding of CD2 and CD58 2 8 0.10 7.59 2.76
170 INT137230 Trh Regulation of Gene_expression of Oprd1 2 1 0.01 1.62 2.75
171 INT317551 Binding of Akt1 and Oprm1 3 1 0.19 0.21 2.74
172 INT202974 Binding of BAG3 and CPP 1 1 0.25 6.22 2.73
173 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 1 0.26 0 2.73
174 INT140347 Binding of ATP1A2 and Cacna1a 3 1 0.11 2.88 2.73
175 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 1 0.17 0.55 2.7
176 INT134294 Binding of Pdyn and Penk 2 1 0.23 0 2.69
177 INT220061 Binding of TRPV1 and TRPA1 1 1 0.15 1.7 2.69
178 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 1 0.09 4.04 2.69
179 INT114134 Penk Positive_regulation of Oprm1 1 2 0.24 1.48 2.68
180 INT182564 Binding of Ptger2 and Trpv1 3 1 0.18 1.77 2.67
181 INT259231 Binding of Oprm1 and Ppp1r9b 3 1 0.01 0 2.67
182 INT92738 Binding of Ephb1 and Tcas1 1 1 0.00 0.43 2.67
183 INT150457 Binding of Sort1 and Prss12 3 3 0.21 1.36 2.64
184 INT326585 Binding of GYPA and SLC6A3 3 1 0.13 0.86 2.64
185 INT259198 Oprm1 Negative_regulation of Binding of Oprm1 and Flna 2 1 0.00 0 2.64
186 INT259214 Oprm1 Negative_regulation of Binding of Flna and Flna 2 1 0.01 0 2.64
187 INT351444 Grin1 Positive_regulation of Gria2 2 1 0.22 1.5 2.64
188 INT7888 Oprl1 Regulation of Localization of Avp 1 4 0.49 0.25 2.63
189 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 3 1 0.38 0.86 2.63
190 INT25708 Oprl1 Positive_regulation of Adra2a 3 1 0.25 0.15 2.63
191 INT152113 Binding of NTSR1 and Ngf 1 3 0.33 2.09 2.62
192 INT251150 Binding of Nos1 and Dlg2 3 1 0.30 1.98 2.62
193 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 1 2 0.49 2.75 2.61
194 INT121742 Prkcg Positive_regulation of Ephb1 3 3 0.49 0.99 2.6
195 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 2 1 0.06 0.5 2.6
196 INT189490 Binding of Ccr3 and Ccl5 2 1 0.33 8.54 2.6
197 INT150596 Binding of Oprd1 and Oprk1 3 1 0.08 0.14 2.59
198 INT67663 Ins1 Positive_regulation of Ntrk2 3 1 0.00 0.19 2.59
199 INT152501 Binding of Tnf and Tnfrsf1a 2 4 0.31 3 2.58
200 INT210696 Trpv1 Regulation of Slc12a2 3 1 0.25 1.97 2.58

Single Events

The table below shows the top 100 pain related interactions that have been reported for plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported in plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
3 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
4 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
5 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
6 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81
7 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
8 INT5660 Binding of Oprd1 477 0.48 71.86 342.06
9 INT876 Localization of Gh1 843 0.80 67.75 340.82
10 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
11 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
12 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32
13 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
14 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41
15 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
16 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14
17 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
18 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
19 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05
20 INT6852 Localization of TNF 883 0.81 705.95 270.84
21 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
22 INT1893 Localization of Gh 1041 0.79 340.23 256.58
23 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9
24 INT5597 Gene_expression of Pdyn 433 0.78 62.97 235.47
25 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87
26 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
27 INT1212 Binding of Oprl1 312 0.48 28.6 225.15
28 INT6481 Binding of TNF 624 0.48 510.2 214.82
29 INT767 Localization of Gnrhr 565 0.80 106.68 214.57
30 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
31 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
32 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
33 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
34 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
35 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66
36 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74
37 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
38 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65
39 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
40 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11
41 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
42 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
43 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93
44 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78
45 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55
46 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
47 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
48 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
49 INT9660 Regulation of TNF 363 0.62 312.94 139.99
50 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99
51 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
52 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16
53 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9
54 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
55 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
56 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14
57 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
58 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74
59 INT1878 Binding of HLA-B 440 0.48 321.16 127.36
60 INT6822 Gene_expression of Pdyn 215 0.78 35.99 125.76
61 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34
62 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
63 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11
64 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
65 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
66 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
67 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
68 INT1530 Regulation of Gh 382 0.61 115.96 112.47
69 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9
70 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
71 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
72 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
73 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
74 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
75 INT12569 Localization of Oprd1 94 0.81 23.81 104.56
76 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83
77 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6
78 INT114 Binding of Oprl1 139 0.48 23 103.35
79 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
80 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
81 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
82 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
83 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76
84 INT65500 Gene_expression of App 605 0.78 429.94 98.31
85 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
86 INT56130 Gene_expression of MC1R 259 0.78 62.7 97.55
87 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4
88 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
89 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
90 INT29971 Gene_expression of Oprk1 126 0.78 35.32 93.97
91 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
92 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
93 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79
94 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
95 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02
96 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
97 INT6437 Binding of YY1 154 0.47 26.3 90.46
98 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
99 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
100 INT18032 Positive_regulation of Oprk1 108 0.70 30.78 89.7
101 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
102 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
103 INT10166 Localization of Tnf 237 0.81 153.95 88.64
104 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
105 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
106 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63
107 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
108 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
109 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
110 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
111 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02
112 INT339 Regulation of Trh 156 0.62 39.27 83.55
113 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
114 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56
115 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5
116 INT403 Localization of Trh 241 0.81 28.55 81.45
117 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
118 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
119 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
120 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35
121 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64
122 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98
123 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46
124 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37
125 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
126 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13
127 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88
128 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
129 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
130 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
131 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
132 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
133 INT5593 Positive_regulation of Gene_expression of Pdyn 114 0.70 29.1 74.46
134 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
135 INT7028 Localization of Pdyn 90 0.81 8.89 73.54
136 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
137 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16
138 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
139 INT442 Localization of PDYN 99 0.81 11.87 72.75
140 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68
141 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
142 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
143 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
144 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06
145 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
146 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
147 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
148 INT1376 Binding of Trh 121 0.48 20 69.86
149 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83
150 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
151 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
152 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
153 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
154 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
155 INT7134 Localization of KNG1 127 0.79 65.73 67.97
156 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
157 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
158 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
159 INT6824 Regulation of Gene_expression of Pdyn 114 0.62 9.48 66.73
160 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17
161 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
162 INT6926 Regulation of Pag1 72 0.39 55.79 65.09
163 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
164 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
165 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23
166 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
167 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
168 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1
169 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
170 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
171 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42
172 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
173 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04
174 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52
175 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
176 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
177 INT1430 Regulation of PDYN 88 0.60 16.99 60.32
178 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98
179 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
180 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
181 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
182 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
183 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
184 INT7032 Positive_regulation of Pdyn 94 0.66 26.51 58.83
185 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
186 INT7491 Localization of Pdyn 80 0.81 3.94 58.77
187 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
188 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67
189 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62
190 INT770 Regulation of Localization of Gnrhr 127 0.61 17.91 58.23
191 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18
192 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
193 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
194 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
195 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59
196 INT21737 Binding of MC1R 129 0.48 45.45 56.54
197 INT1510 Binding of PDYN 94 0.48 4.68 56.44
198 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35
199 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
200 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82
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