GOS:protein complex assembly

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This page displays the top molecular interactions and top single events that were mentioned in the literature for protein complex assembly. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein complex assembly. They are ordered first by their pain relevance and then by number of times they were reported for protein complex assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to protein complex assembly Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 1 0.01 28.19 40.6
2 INT206768 TP53 Positive_regulation of Ltp 1 2 0.01 5.83 10.21
3 INT296275 Binding of Dlg4 and Kcnip3 1 1 0.39 3.58 5.6
4 INT101942 Binding of CD40 and CD40LG 1 16 0.23 15.24 4.01
5 INT104977 MITF Regulation of Gene_expression of MC1R 1 1 0.69 0.91 3.71
6 INT85042 Binding of CCT6A and MAX 1 1 0.00 0 3.13
7 INT156381 Binding of Grin1 and Dlg4 2 1 0.39 0.86 2.9
8 INT253988 Binding of Cd74 and Mif 2 1 0.36 6.57 2.52
9 INT85041 Binding of IGHG3 and MAX 1 1 0.00 0 2.09
10 INT296280 Binding of Car2 and Dlg4 1 1 0.19 0.45 1.71
11 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 1 0.01 0.95 1.67
12 INT236491 GCH1 Regulation of Pain1 1 1 0.01 0.89 1.65
13 INT284785 Gch1 Regulation of Bh4p 1 1 0.00 1.48 1.54
14 INT104975 MITF Regulation of Transcription of PRSS1 1 1 0.68 0.35 1.46
15 INT104972 MITF Regulation of Transcription of TYR 1 1 0.20 0.35 1.45
16 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 1 0.12 0.16 1.34
17 INT135830 Gch1 Regulation of Nos2 1 1 0.65 0 1.29
18 INT105295 WAS Regulation of PTGS1 1 1 0.02 0.13 1.27
19 INT84886 APC Regulation of PPARD 1 1 0.51 1.57 1.26
20 INT251142 Binding of Dlg4 and Grin2a 1 3 0.30 0.5 1.24
21 INT105918 Binding of FUT1 and SLC9A3R2 1 1 0.00 0.14 1.2
22 INT139736 Htr1a Positive_regulation of Mapk3 1 1 0.54 0.13 1.19
23 INT340439 Binding of HLA-DMA and SUGT1 1 1 0.00 4.1 1.16
24 INT212815 WAS Positive_regulation of CNR1 1 1 0.01 0.62 1.16
25 INT212824 WAS Positive_regulation of Cnr1 1 1 0.21 0.62 1.16
26 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 1 0.50 0.2 1.09
27 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 1 0.75 0.2 1.08
28 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 1 0.54 0.2 1.08
29 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 1 0.00 0 1.06
30 INT329959 Binding of TRAF1 and HEPACAM 1 1 0.03 2.25 1.06
31 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 1 0.09 1.54 1.05
32 INT85039 Binding of GPM6A and MAX 1 1 0.00 0 1.05
33 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 1 0.46 1.03 1.02
34 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 1 0.02 0.36 1.01
35 INT91813 Binding of FAS and FASLG 1 4 0.23 9.89 0.99
36 INT156380 Regulation of Binding of Grin1 and Dlg4 2 1 0.29 0.32 0.97
37 INT296179 Pla2g2a Positive_regulation of Apcs 1 1 0.17 7.13 0.96
38 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 1 0.06 0.99 0.96
39 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 1 0.30 1.76 0.94
40 INT34271 Positive_regulation of WAS Positive_regulation of Oprd1 1 1 0.01 0 0.91
41 INT34273 WAS Regulation of Oprd1 1 1 0.00 0 0.91
42 INT34272 WAS Positive_regulation of Oprd1 1 1 0.01 0 0.91
43 INT135446 Map2k1 Positive_regulation of Mapk3 1 1 0.54 0.25 0.91
44 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 1 0.22 0 0.9
45 INT48342 Pde8a Regulation of Ahsg 1 1 0.24 0 0.9
46 INT97738 Mdk Positive_regulation of Mapk3 1 1 0.08 0.66 0.87
47 INT97735 Trib3 Positive_regulation of Mapk3 1 1 0.05 0.66 0.87
48 INT130769 FASLG Negative_regulation of Binding of FAS and 1 1 0.10 0.66 0.86
49 INT330630 Binding of TP53 and Car1 1 1 0.23 1.56 0.86
50 INT120820 Binding of ASIC3 and Dlg4 1 3 0.02 0.11 0.84
51 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 1 0.36 0.51 0.83
52 INT97058 Cpz Regulation of Gene_expression of Trp53 1 1 0.27 0.57 0.83
53 INT155760 Binding of Nos1 and Dlg4 2 1 0.13 1.01 0.82
54 INT152947 Dlg4 Regulation of Sgk1 1 1 0.09 0.18 0.76
55 INT152945 Dlg4 Regulation of Cap1 1 1 0.11 0.18 0.76
56 INT155096 Stat3 Regulation of Mapk3 1 1 0.36 0.45 0.76
57 INT152944 Dlg4 Regulation of Gpr88 1 1 0.12 0.18 0.75
58 INT104974 MITF Positive_regulation of MC1R 1 1 0.52 0.16 0.74
59 INT195778 Binding of APC and PROCR 1 7 0.19 3.78 0.73
60 INT228499 Binding of FAS and Fasl 1 1 0.15 2.75 0.73
61 INT106992 F2 Positive_regulation of PARD3 1 3 0.05 1.83 0.72
62 INT168911 Grm5 Regulation of Mapk3 1 1 0.17 0.78 0.71
63 INT16048 MAX Positive_regulation of SLC25A4 1 1 0.50 0 0.71
64 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 1 0.52 2.45 0.67
65 INT211915 Fig4 Positive_regulation of Mapk3 1 1 0.12 0.25 0.66
66 INT168205 Binding of Dlg4 and Pik3cd 1 1 0.11 0.37 0.65
67 INT169296 PTPLA Positive_regulation of MAPK3 1 1 0.10 0.15 0.63
68 INT121713 WAS Positive_regulation of Gene_expression of SELP 1 1 0.30 0.49 0.63
69 INT115592 IRF6 Positive_regulation of Gene_expression of FAS 1 1 0.34 0.34 0.62
70 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 1 0.27 0.83 0.61
71 INT92998 Positive_regulation of SFTPA1 Positive_regulation of Localization of CD40 1 1 0.15 0.34 0.61
72 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 1 0.48 1.33 0.59
73 INT92999 Binding of CD40 and VCAM1 1 1 0.39 0.33 0.57
74 INT80030 Binding of FAS and TNF 1 3 0.27 2.54 0.56
75 INT96089 Binding of F2 and Pf4 1 1 0.00 1.31 0.56
76 INT195773 Binding of Cd74 and Mif 1 2 0.25 2.78 0.55
77 INT99486 OPRM1 Positive_regulation of MAPK3 1 1 0.22 0 0.55
78 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 1 0.00 1.4 0.55
79 INT251141 Binding of Dlg4 and Grin2b 1 1 0.14 0.32 0.55
80 INT160780 Cps1 Positive_regulation of Positive_regulation of FAS 1 1 0.01 1 0.55
81 INT106394 MAPK3 Positive_regulation of ADRBK1 1 1 0.48 0.06 0.53
82 INT164264 TGM7 Negative_regulation of CCNB1 1 1 0.07 1.08 0.53
83 INT168256 Binding of MLL and TNFRSF1B 1 1 0.00 1.2 0.53
84 INT254200 Mif Regulation of Trp53 1 1 0.02 0.96 0.52
85 INT346205 Binding of CD74 and TPPP 1 1 0.02 0.87 0.51
86 INT131371 MAPK3 Positive_regulation of Il4 1 1 0.02 0.37 0.51
87 INT131367 MAPK3 Positive_regulation of Bcar3 1 1 0.00 0.37 0.51
88 INT131370 MAPK3 Positive_regulation of Gene_expression of Il4 1 1 0.02 0.37 0.51
89 INT321598 Binding of MLL and TNF 1 1 0.05 1.07 0.49
90 INT114676 Mdm2 Negative_regulation of p53-ps 1 1 0.10 0.26 0.48
91 INT182150 Binding of APC and DCPS 1 1 0.02 1.14 0.48
92 INT263746 Binding of Dlg4 and Neto1 1 1 0.27 0 0.48
93 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 1 0.03 0.96 0.48
94 INT90262 Binding of TAT and Pf4 1 1 0.03 5.64 0.48
95 INT102552 HGF Positive_regulation of MAPK3 1 1 0.38 0.47 0.47
96 INT109780 WAS Regulation of Localization of Acot1 1 1 0.01 0.26 0.46
97 INT60935 Negative_regulation of Maoa Negative_regulation of Apcs 1 1 0.33 0.17 0.46
98 INT195774 Binding of MIF and Cd74 1 1 0.02 1.15 0.46
99 INT198931 Binding of Dlg4 and Lrp8 1 1 0.06 0.23 0.46
100 INT96095 Binding of Selp and Pf4 1 1 0.01 1.2 0.45
101 INT96097 Binding of SELP and Pf4 1 1 0.13 1.2 0.45
102 INT159755 HP Regulation of OXA1L 1 1 0.01 0 0.44
103 INT340438 Binding of HLA-DMA and MRAP 1 1 0.02 1.69 0.43
104 INT302829 Mapkapk5 Positive_regulation of Trp53 1 1 0.07 0.81 0.43
105 INT142171 Positive_regulation of Adarb1 Positive_regulation of Apcs 1 1 0.01 0.19 0.43
106 INT296477 Binding of Cacng2 and Dlg4 1 1 0.04 0.22 0.42
107 INT135426 Binding of APBB1 and Dlg4 1 1 0.00 0.17 0.42
108 INT106396 DYT10 Positive_regulation of MAPK3 1 1 0.50 0 0.42
109 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 1 0.11 0.39 0.42
110 INT225738 Binding of RANBP9 and Entpd1 1 1 0.13 0.3 0.42
111 INT329960 Binding of C5 and TRAF1 1 1 0.32 1.04 0.42
112 INT84885 APC Regulation of APC Regulation of PPARD 1 1 0.18 0.55 0.41
113 INT329955 Binding of STAT4 and TRAF1 1 1 0.38 0.93 0.4
114 INT96833 Binding of WAS and Positive_regulation of Cnr1 1 1 0.02 0.69 0.39
115 INT96834 Binding of WAS and Positive_regulation of Cnr2 1 1 0.03 0.69 0.39
116 INT96836 WAS Positive_regulation of Cnr1 1 1 0.02 0.69 0.39
117 INT96835 WAS Positive_regulation of Cnr2 1 1 0.03 0.69 0.39
118 INT339511 Binding of Tlr4 and Traf6 1 1 0.05 0.12 0.38
119 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 1 0.05 0.17 0.38
120 INT339506 Binding of Irak1 and Traf6 1 1 0.03 0.12 0.37
121 INT355018 Binding of FAS and Faslg 1 1 0.12 1.34 0.37
122 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 1 0.36 0.55 0.37
123 INT120821 Dlg4 Positive_regulation of ASIC3 1 1 0.02 0 0.36
124 INT164890 Binding of IL1RAP and IL33 1 1 0.09 0.2 0.36
125 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 1 0.00 0.61 0.35
126 INT272602 Binding of Dlg4 and Gria2 1 3 0.09 0.19 0.34
127 INT120817 Binding of Dlg4 and Lin7b 1 1 0.00 0 0.34
128 INT296465 Binding of Dlg4 and Rbm39 1 1 0.00 0.05 0.34
129 INT324690 Binding of Traf6 and Ticam1 1 2 0.07 0.23 0.33
130 INT324224 Binding of OTX2 and H9 1 1 0.11 0.17 0.33
131 INT165764 Tnfsf11 Positive_regulation of Mapk3 1 1 0.17 1.08 0.33
132 INT283841 Dlg4 Negative_regulation of Insrr 1 1 0.01 0.95 0.33
133 INT165763 Tnfsf11 Positive_regulation of Phosphorylation of Mapk3 1 1 0.40 1.08 0.33
134 INT214987 Binding of FANCC and Sigmar1 1 1 0.06 0.34 0.32
135 INT100028 TNF Positive_regulation of Mapk3 1 1 0.22 0.79 0.32
136 INT203089 Binding of Il1a and Traf6 1 1 0.04 0.66 0.32
137 INT91814 Binding of TNF and TP53 1 1 0.14 2.2 0.32
138 INT195665 APC Negative_regulation of F8 1 1 0.04 1.53 0.32
139 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 1 0.13 1.53 0.32
140 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 1 0.06 0.67 0.32
141 INT198779 Binding of Dlg4 and Psd 1 10 0.25 0.09 0.31
142 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 1 0.28 0.41 0.31
143 INT90263 Binding of PPBP and Pf4 1 1 0.03 3.71 0.31
144 INT166396 IFI27 Regulation of Gene_expression of TP53 1 1 0.19 0.41 0.31
145 INT195664 APC Negative_regulation of F5 1 1 0.08 1.51 0.31
146 INT80029 Binding of FAS and Positive_regulation of NFKB1 1 1 0.34 0.92 0.3
147 INT63122 Binding of APC and Man2a2 1 1 0.01 0.15 0.3
148 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 2 1 0.01 1.23 0.3
149 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 1 0.27 0.86 0.3
150 INT333918 HDAC1 Regulation of Trp53 1 1 0.03 1.24 0.3
151 INT255292 Regulation of Binding of Napb and Vamp2 1 1 0.07 0 0.3
152 INT80031 FAS Positive_regulation of Positive_regulation of NFKB1 1 1 0.50 0.93 0.3
153 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 1 0.30 0.99 0.3
154 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 2 1 0.40 0.86 0.3
155 INT255286 Binding of Napb and Vamp2 1 1 0.09 0 0.29
156 INT326438 Binding of HFE and TAPVR1 1 1 0.01 0.48 0.29
157 INT255284 Binding of Vamp2 and Vti1b 1 1 0.16 0 0.29
158 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 1 0.05 0.75 0.28
159 INT228500 Fadd Positive_regulation of FAS 1 1 0.14 1.12 0.28
160 INT135425 Binding of Dlg4 and Dlg3 1 1 0.29 0.07 0.28
161 INT289954 Binding of APC and CD28 1 1 0.03 0.38 0.28
162 INT286042 Binding of Tp53 and Wwox 1 1 0.04 2.05 0.28
163 INT216127 EGR1 Regulation of Transcription of TP53 1 1 0.06 0.21 0.28
164 INT179423 Fig4 Regulation of Mapk3 1 1 0.02 0.32 0.28
165 INT166156 Ccr9 Positive_regulation of Mapk3 1 1 0.49 1.47 0.28
166 INT302837 Binding of TNFRSF10D and Trp53 1 1 0.01 0.98 0.28
167 INT274944 Binding of Dlg4 and Pick1 1 1 0.04 0 0.28
168 INT238632 Binding of EPB41 and Cask 1 1 0.44 0.78 0.27
169 INT306267 Binding of INCENP and TP53 1 1 0.02 0.83 0.27
170 INT350813 Binding of Apc and Crp 1 1 0.18 1.12 0.27
171 INT32147 LLGL1 Positive_regulation of Gene_expression of IFNA1 1 1 0.13 0 0.27
172 INT216128 EGR1 Regulation of TP53 1 1 0.11 0.21 0.27
173 INT134645 Binding of ORM1 and OXA1L 1 1 0.17 0.1 0.27
174 INT237928 BCL2 Positive_regulation of FAS 1 1 0.02 1.41 0.26
175 INT352931 Prkaca Regulation of TP53 1 1 0.13 1.01 0.26
176 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 1 0.13 1.02 0.26
177 INT32149 Binding of ENG and LLGL1 1 1 0.11 0 0.26
178 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 1 0.01 1.34 0.26
179 INT124117 Apcs Negative_regulation of Ednra 1 1 0.09 0 0.26
180 INT172975 Trp53 Positive_regulation of Cdkn1a 1 1 0.03 1.35 0.26
181 INT352893 PTGDS Regulation of TP53 1 1 0.16 1.02 0.26
182 INT125516 TP53 Regulation of GDF15 1 1 0.10 0.47 0.26
183 INT274939 Binding of Dlg4 and Ephb6 1 1 0.12 0 0.25
184 INT337086 Mif Negative_regulation of Localization of Trp53 1 1 0.16 1.64 0.25
185 INT191876 Pbsn Positive_regulation of Mapk3 1 1 0.01 0.33 0.25
186 INT191894 Prkca Positive_regulation of Mapk3 1 1 0.05 0.33 0.25
187 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 1 0.16 1.64 0.25
188 INT314045 THL Negative_regulation of Phosphorylation of Mapk3 1 1 0.13 0.7 0.25
189 INT235976 Binding of APC and Trav6-3 1 2 0.01 2.62 0.24
190 INT213804 Binding of Mitf and Tfeb 1 1 0.24 0.81 0.24
191 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 1 0.00 1.15 0.24
192 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 1 0.45 0.9 0.24
193 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 1 0.03 0.94 0.24
194 INT235972 Negative_regulation of Binding of APC and Bcr 1 1 0.01 1.15 0.24
195 INT235973 Binding of APC and Bcr 1 1 0.01 1.14 0.24
196 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 1 0.49 0.89 0.24
197 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 1 0.04 1.41 0.24
198 INT263787 Binding of GRIN1 and Dlg4 1 3 0.18 0.05 0.23
199 INT191887 Pbsn Regulation of Phosphorylation of Mapk3 1 1 0.00 0.24 0.23
200 INT191879 Positive_regulation of Pbsn Negative_regulation of Positive_regulation of Mapk3 1 1 0.01 0.25 0.23

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein complex assembly. They are ordered first by their pain relevance and then by number of times they were reported in protein complex assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
2 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
3 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
4 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
5 INT162102 Gene_expression of Gch1 3 0.72 23.65 27.96
6 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
7 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
8 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
9 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
10 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
11 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
12 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
13 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
14 INT1850 Binding of OXA1L 77 0.48 7.61 15.22
15 INT97100 Negative_regulation of Dlg4 16 0.58 6.18 14.36
16 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96
17 INT111529 Phosphorylation of Mapk3 41 0.80 21.14 13.72
18 INT48927 Regulation of Mapk3 25 0.60 14.06 12.82
19 INT88789 Gene_expression of Dlg4 26 0.78 4.41 12.74
20 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
21 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83
22 INT14962 Gene_expression of Pf4 27 0.76 22.48 10.88
23 INT238920 Positive_regulation of SLC9A3R2 44 0.50 27.86 10.51
24 INT288515 Negative_regulation of Gene_expression of Gch1 1 0.47 9.26 10.41
25 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38
26 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
27 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
28 INT288526 Negative_regulation of Gch1 1 0.54 8.59 9.6
29 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4
30 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9
31 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
32 INT34268 Binding of WAS 14 0.47 4.41 8.67
33 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
34 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51
35 INT45914 Gene_expression of Apcs 22 0.65 24.25 8.48
36 INT24141 Negative_regulation of Apcs 24 0.59 16.82 8.29
37 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
38 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03
39 INT82762 Positive_regulation of Positive_regulation of Mapk3 23 0.67 7.72 7.91
40 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
41 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69
42 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
43 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
44 INT152347 Binding of GCH1 8 0.37 6.13 7.36
45 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
46 INT33105 Regulation of WAS 11 0.60 3.61 7.18
47 INT93003 Binding of CD40 28 0.47 20.25 7.13
48 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
49 INT97099 Positive_regulation of Dlg4 13 0.60 3.04 6.98
50 INT104979 Gene_expression of MITF 51 0.62 54.83 6.91
51 INT88786 Binding of Dlg4 11 0.46 2.73 6.58
52 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
53 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
54 INT163776 Regulation of GCH1 7 0.27 4.58 6.16
55 INT48926 Positive_regulation of Gene_expression of Mapk3 12 0.46 6.02 6.13
56 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
57 INT288524 Positive_regulation of Gene_expression of Gch1 1 0.56 5.03 6.02
58 INT19941 Negative_regulation of Pf4 13 0.42 10.35 5.97
59 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
60 INT80033 Binding of FAS 37 0.48 41.19 5.67
61 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
62 INT111470 Positive_regulation of EPRS 18 0.44 11.42 5.29
63 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
64 INT60585 Regulation of TP53 59 0.59 54.55 5.21
65 INT61452 Gene_expression of IL1RAP 15 0.58 7.21 5.09
66 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
67 INT94103 Gene_expression of EPRS 13 0.54 11.47 4.99
68 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
69 INT88790 Negative_regulation of Gene_expression of Dlg4 6 0.59 1.53 4.66
70 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
71 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
72 INT145532 Localization of Dlg4 25 0.79 1.97 4.36
73 INT111535 Negative_regulation of Phosphorylation of Mapk3 9 0.57 6.39 4.31
74 INT88787 Transcription of Dlg4 4 0.69 0.83 4.09
75 INT253970 Positive_regulation of Cd74 3 0.48 8.16 4.09
76 INT120810 Binding of Dlg4 38 0.41 3.55 4.03
77 INT112782 Localization of Mapk3 8 0.78 1.87 3.98
78 INT48456 Localization of WAS 6 0.56 1.63 3.95
79 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
80 INT123827 Positive_regulation of Phosphorylation of Mapk3 10 0.67 5.22 3.82
81 INT63121 Binding of APC 29 0.41 23.02 3.8
82 INT94291 Regulation of Gene_expression of Mapk3 4 0.40 3.05 3.8
83 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
84 INT60933 Positive_regulation of Apcs 16 0.67 11.69 3.68
85 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47
86 INT187168 Binding of Cd74 13 0.27 11.2 3.44
87 INT93915 Positive_regulation of Gene_expression of CD40 14 0.44 12.45 3.35
88 INT129751 Regulation of Phosphorylation of Mapk3 11 0.55 3.91 3.35
89 INT135815 Transcription of Gch1 1 0.60 0 3.32
90 INT97737 Negative_regulation of Phosphorylation of Mapk3 9 0.57 5.64 3.3
91 INT288517 Regulation of Gch1 1 0.50 2.96 3.19
92 INT66347 Gene_expression of MLL 29 0.65 14.82 3.18
93 INT93913 Positive_regulation of CD40 21 0.58 23.47 3.1
94 INT105297 Negative_regulation of Regulation of WAS 3 0.28 0.98 3.07
95 INT71783 Positive_regulation of Gene_expression of MAPK3 9 0.59 4.59 3.05
96 INT87288 Positive_regulation of Positive_regulation of MAPK3 5 0.67 1.62 3.04
97 INT8103 Binding of TP53 46 0.44 40.2 2.96
98 INT41358 Localization of Pf4 11 0.79 6.06 2.89
99 INT32394 Regulation of Pf4 12 0.23 6.07 2.85
100 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
101 INT36489 Regulation of Apcs 12 0.58 10.6 2.78
102 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77
103 INT79476 Gene_expression of HLA-DMA 23 0.38 9.5 2.76
104 INT243350 Binding of CD74 2 0.11 4.86 2.72
105 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
106 INT63869 Positive_regulation of IL1RAP 8 0.45 3.84 2.63
107 INT288516 Negative_regulation of Negative_regulation of Gch1 1 0.40 2.35 2.59
108 INT150932 Positive_regulation of Gene_expression of GCH1 3 0.70 2.07 2.57
109 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
110 INT346375 Protein_catabolism of Vamp2 1 0.33 1.56 2.46
111 INT249378 Negative_regulation of Vamp2 3 0.20 0.27 2.4
112 INT87284 Negative_regulation of Positive_regulation of MAPK3 7 0.41 2.65 2.38
113 INT55952 Transcription of TP53 16 0.61 12.14 2.36
114 INT288514 Positive_regulation of Gch1 1 0.43 1.91 2.35
115 INT95898 Gene_expression of CAPG 14 0.39 10.51 2.33
116 INT283973 Transcription of GCH1 1 0.61 1.99 2.33
117 INT283975 Negative_regulation of Localization of GCH1 1 0.38 1.99 2.27
118 INT93753 Positive_regulation of Tap2 1 0.57 1.31 2.21
119 INT135827 Positive_regulation of Transcription of Gch1 1 0.58 0 2.2
120 INT63058 Positive_regulation of MATN1 1 0.61 0.88 2.15
121 INT134874 Regulation of Dlg4 3 0.58 0.28 2.12
122 INT92415 Positive_regulation of Max 4 0.67 1.13 2.1
123 INT98132 Regulation of FAS 16 0.42 20.57 2.06
124 INT102176 Transcription of FAS 3 0.60 3.22 2.05
125 INT258637 Regulation of Gene_expression of GCH1 1 0.62 1.77 2.02
126 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
127 INT121781 Regulation of Mapk3 5 0.44 1.96 1.98
128 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
129 INT248374 Binding of IKBKAP 10 0.42 10.45 1.9
130 INT238608 Gene_expression of Cask 1 0.73 2.74 1.9
131 INT65855 Localization of TP53 18 0.76 17.08 1.89
132 INT253975 Binding of Cd74 4 0.27 4.57 1.88
133 INT135820 Regulation of Gch1 1 0.59 0 1.88
134 INT198748 Regulation of Gene_expression of Dlg4 10 0.44 2.16 1.85
135 INT47885 Gene_expression of Max 5 0.65 0.54 1.84
136 INT118683 Regulation of Phosphorylation of MAPK3 3 0.44 2.92 1.82
137 INT8787 Negative_regulation of WAS 4 0.42 2.42 1.81
138 INT293158 Gene_expression of TRAF1 2 0.63 3.62 1.81
139 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
140 INT97750 Positive_regulation of Positive_regulation of FAS 4 0.49 4.9 1.8
141 INT139459 Negative_regulation of MAX 6 0.57 0.32 1.79
142 INT82760 Negative_regulation of Positive_regulation of Mapk3 7 0.57 3.18 1.78
143 INT105920 Binding of SLC9A3R2 5 0.36 1.99 1.75
144 INT157762 Localization of EPRS 6 0.60 5.29 1.73
145 INT14961 Positive_regulation of Gene_expression of Pf4 4 0.30 3.42 1.7
146 INT75352 Negative_regulation of Mgp 1 0.58 0 1.7
147 INT3818 Regulation of Apc 13 0.39 12.52 1.68
148 INT97062 Binding of PML 10 0.41 11.63 1.65
149 INT58456 Gene_expression of HFE 10 0.58 7.68 1.65
150 INT87282 Regulation of MAPK3 9 0.60 7.61 1.65
151 INT337100 Gene_expression of Mgp 3 0.71 45.04 1.64
152 INT107012 Binding of EPRS 5 0.30 2.92 1.63
153 INT149994 Gene_expression of Mapk3 16 0.65 3.45 1.62
154 INT129053 Regulation of EPRS 3 0.17 2.79 1.6
155 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55
156 INT86035 Positive_regulation of Max 2 0.49 0.49 1.54
157 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
158 INT48412 Gene_expression of Apcs 26 0.54 7.16 1.53
159 INT103799 Positive_regulation of CAPG 8 0.34 5.16 1.52
160 INT82761 Regulation of Positive_regulation of Mapk3 3 0.40 1.34 1.52
161 INT119219 Localization of Dlg4 3 0.64 0.16 1.5
162 INT152939 Regulation of Dlg4 9 0.60 1.09 1.49
163 INT132886 Negative_regulation of Positive_regulation of Mapk3 2 0.30 1.27 1.49
164 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
165 INT217825 Regulation of Gene_expression of MITF 3 0.00 5.2 1.47
166 INT58032 Positive_regulation of Localization of Pf4 3 0.67 1.72 1.46
167 INT93001 Localization of CD40 4 0.78 1.97 1.45
168 INT1851 Regulation of OXA1L 7 0.40 0.59 1.42
169 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
170 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
171 INT134873 Phosphorylation of Dlg4 3 0.80 0.5 1.42
172 INT288522 Positive_regulation of Transcription of Gch1 1 0.64 1.06 1.42
173 INT172953 Binding of Trp53 33 0.37 20.76 1.41
174 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
175 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
176 INT288525 Transcription of Gch1 1 0.66 1.06 1.41
177 INT271443 Regulation of Cd74 1 0.33 2.73 1.4
178 INT123346 Gene_expression of LAMC1 1 0.36 2.73 1.39
179 INT114671 Positive_regulation of Mdm2 1 0.61 0.5 1.38
180 INT220177 Binding of Apc 21 0.37 15.34 1.37
181 INT145221 Binding of Tp53 10 0.37 8.59 1.37
182 INT54020 Regulation of Binding of OXA1L 4 0.51 0.27 1.37
183 INT329968 Binding of TRAF1 1 0.45 3.42 1.37
184 INT35271 Negative_regulation of Apcs 12 0.59 8.05 1.36
185 INT135822 Gene_expression of Gch1 2 0.50 0.77 1.35
186 INT130773 Regulation of Gene_expression of FAS 5 0.37 6.87 1.32
187 INT107010 Protein_catabolism of EPRS 5 0.79 2.32 1.31
188 INT91298 Negative_regulation of EPRS 4 0.40 0.79 1.31
189 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
190 INT181526 Positive_regulation of Apcs 13 0.49 4.09 1.3
191 INT97098 Regulation of Negative_regulation of Dlg4 3 0.45 0.97 1.3
192 INT288521 Protein_catabolism of Gch1 1 0.61 1.17 1.3
193 INT214983 Positive_regulation of FANCC 11 0.15 1.81 1.29
194 INT74287 Regulation of IL1RAP 1 0.05 0.8 1.29
195 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
196 INT190067 Binding of Traf2 5 0.20 3.28 1.27
197 INT288523 Regulation of Binding of Gch1 1 0.36 0.91 1.27
198 INT70138 Positive_regulation of Ccnb1 7 0.41 4.31 1.26
199 INT288519 Binding of Gch1 1 0.30 0.9 1.26
200 INT123343 Negative_regulation of LAMC1 1 0.27 2.62 1.26
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