GOS:protein modification process

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This page displays the top molecular interactions and top single events that were mentioned in the literature for protein modification process. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein modification process. They are ordered first by their pain relevance and then by number of times they were reported for protein modification process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to protein modification process Documents TM Confidence Disease Relevance Pain Relevance
1 INT44716 Binding of ABL2 and PDYN 1 2 0.40 0.66 4.77
2 INT202959 Binding of BAG3 and MCRS1 1 1 0.11 7.46 3.14
3 INT14687 Binding of Penk and Ppt1 1 1 0.41 0 2.46
4 INT60867 Binding of G2e3 and Gpm6a 1 2 0.01 0.1 1.93
5 INT68272 Binding of Oprd1 and G2e3 1 1 0.00 0.11 1.93
6 INT68273 G2e3 Negative_regulation of Binding of Oprd1 and G2e3 1 1 0.00 0.11 1.93
7 INT167320 Binding of CPE and OPRM1 1 1 0.14 0.63 1.77
8 INT24689 Binding of PLAT and Serpine1 1 1 0.00 3.77 1.64
9 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 1 1 0.00 2.84 1.58
10 INT202958 Binding of STC2 and MCRS1 1 1 0.01 3.48 1.44
11 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 1 0.06 0.49 1.39
12 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 1 0.26 0.49 1.38
13 INT305408 Binding of KCNMA1 and ST8SIA2 1 1 0.01 0.09 1.24
14 INT7202 Uba3 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 1 0.00 0 1.2
15 INT25026 PLOD1 Regulation of FSHR 1 4 0.19 0.38 1.15
16 INT202960 Binding of MCRS1 and CPP 1 1 0.14 2.49 1.13
17 INT101715 PLAT Positive_regulation of NFKB1 1 2 0.11 0.99 1.09
18 INT108547 AKT1 Regulation of MAPKAPK5 1 1 0.04 1.2 1.08
19 INT202968 Binding of MCRS1 and CAP1 1 1 0.03 2.46 1.08
20 INT153039 Binding of G2e3 and LOC100360318 1 1 0.00 0 1.01
21 INT4916 Binding of Pax3 and Wdyhv1 1 1 0.00 0 0.98
22 INT70802 Ngf Regulation of Ppt1 1 1 0.21 0.39 0.93
23 INT61698 G2e3 Regulation of Localization of Abat 1 1 0.05 0 0.88
24 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 1 3 0.50 0.78 0.86
25 INT305406 Binding of CAV3 and ST8SIA2 1 1 0.16 0 0.86
26 INT34740 BID Regulation of Gene_expression of PLOD1 1 1 0.01 0 0.83
27 INT116106 VEGFA Positive_regulation of AKT1 1 1 0.12 0.3 0.83
28 INT104749 Ugt1a1 Regulation of Positive_regulation of G2e3 1 1 0.00 0.07 0.77
29 INT125523 PLAT Positive_regulation of GDF15 1 1 0.13 1.33 0.75
30 INT202967 MCRS1 Negative_regulation of CPP 1 2 0.14 2.2 0.73
31 INT128684 Binding of TGM1 and RETNLB 1 1 0.00 2.46 0.72
32 INT169293 PTPLA Positive_regulation of AKT1 1 1 0.10 0.15 0.64
33 INT45780 GNRH1 Positive_regulation of PLOD1 1 3 0.07 1.02 0.63
34 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 1 0.04 0.81 0.62
35 INT73402 Binding of Oprl1 and Wdyhv1 3 1 0.00 0 0.61
36 INT85489 IRF6 Negative_regulation of PLOD1 1 1 0.01 0.16 0.61
37 INT85488 Negative_regulation of IRF6 Negative_regulation of PLOD1 1 1 0.01 0.16 0.61
38 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 1 0.22 0.06 0.61
39 INT45781 Regulation of GNRH1 Positive_regulation of PLOD1 1 1 0.06 0.16 0.61
40 INT35154 PLOD1 Regulation of PRL 1 2 0.17 0 0.6
41 INT101719 PLAT Positive_regulation of NFYC 1 1 0.13 0.1 0.6
42 INT101717 PLAT Positive_regulation of JUND 1 1 0.17 0.1 0.59
43 INT37034 PLAT Positive_regulation of PLDN 1 1 0.08 0.15 0.58
44 INT345303 MMP15 Positive_regulation of MMP13 1 1 0.00 1.18 0.58
45 INT37035 PLAT Negative_regulation of ODC1 1 1 0.45 0.15 0.58
46 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 1 0.16 1.64 0.57
47 INT202961 MCRS1 Negative_regulation of STC2 1 1 0.00 1.63 0.57
48 INT345302 MMP15 Positive_regulation of MMP2 1 1 0.06 1.17 0.57
49 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 1 0.09 0.79 0.55
50 INT23485 HBE1 Positive_regulation of Localization of PLOD1 1 1 0.04 0 0.54
51 INT69177 UBA7 Negative_regulation of Igk 1 1 0.00 0.15 0.54
52 INT23482 HBE1 Positive_regulation of PLOD1 1 1 0.04 0 0.53
53 INT70244 POMC Positive_regulation of Localization of PLOD1 1 1 0.21 0 0.53
54 INT23484 Positive_regulation of HBE1 Positive_regulation of PLOD1 1 1 0.04 0 0.53
55 INT69179 Binding of UBA7 and Adarb1 1 1 0.00 0.16 0.53
56 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 1 0.03 0.72 0.51
57 INT202957 CPP Negative_regulation of MCRS1 1 1 0.14 1.53 0.51
58 INT97951 ST3GAL3 Positive_regulation of AKT1 1 1 0.04 0.7 0.5
59 INT39248 NPL Regulation of PLOD1 1 1 0.14 0.16 0.49
60 INT114593 Il1b Positive_regulation of Gene_expression of Ppt1 1 1 0.05 0.06 0.48
61 INT180958 Binding of F13A1 and PLAT 1 2 0.03 2.16 0.47
62 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 1 0.02 1.22 0.47
63 INT202964 SGSM3 Positive_regulation of MCRS1 1 1 0.03 1.21 0.47
64 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 1 0.14 1.01 0.47
65 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 1 0.41 1 0.46
66 INT168699 Binding of Nedd4 and Tyr 1 1 0.02 0.45 0.46
67 INT22674 Binding of SERPINE1 and PLAT 1 7 0.04 0.65 0.45
68 INT63152 Ppt1 Regulation of Gene_expression of Pd 1 1 0.01 0 0.43
69 INT23481 POMC Regulation of Localization of PLOD1 1 1 0.20 0 0.42
70 INT160047 PTEN Regulation of Gene_expression of AKT1 1 1 0.33 0.6 0.42
71 INT125520 PLAT Positive_regulation of Gene_expression of GDF15 1 1 0.13 0.74 0.42
72 INT76154 Binding of NCOR2 and Negative_regulation of Localization of PLOD1 1 1 0.02 0 0.42
73 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 1 0.28 0.6 0.42
74 INT121851 AKT1 Regulation of ROS1 1 1 0.16 0.52 0.41
75 INT114601 Il1b Positive_regulation of Transcription of Ppt1 1 1 0.35 0.1 0.41
76 INT121848 AKT1 Regulation of CASP8 1 1 0.18 0.52 0.41
77 INT121854 AKT1 Regulation of BID 1 1 0.17 0.52 0.41
78 INT108197 AKT1 Regulation of JUN 1 1 0.29 0.25 0.4
79 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 1 0.25 0.49 0.4
80 INT305407 Binding of ST8SIA2 and ANTXR1 1 1 0.00 0.09 0.38
81 INT89386 INS Positive_regulation of Phosphorylation of AKT1 1 3 0.43 1.48 0.36
82 INT299288 AKT1 Positive_regulation of RPTOR 1 1 0.34 0.05 0.36
83 INT97043 Binding of G2e3 and Hist1h3g 1 1 0.01 0.5 0.36
84 INT176135 AKT1 Regulation of Localization of CYCS 1 1 0.43 2.16 0.35
85 INT70935 Nts Regulation of SEPHS1 1 1 0.00 0.38 0.34
86 INT43388 OPRM1 Positive_regulation of Localization of PLOD1 1 1 0.27 0 0.34
87 INT344238 MCRS1 Regulation of TREX1 1 1 0.08 1.02 0.34
88 INT89381 INS Positive_regulation of AKT1 1 6 0.43 3.06 0.33
89 INT214854 SERPINE1 Positive_regulation of PLAT 1 1 0.24 0.42 0.33
90 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 1 0.09 0.5 0.32
91 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 1 0.09 0.5 0.32
92 INT31042 Ghrh Positive_regulation of Localization of PLOD1 1 1 0.08 0 0.32
93 INT31039 Gnrh1 Negative_regulation of Localization of PLOD1 1 1 0.05 0 0.32
94 INT337410 AKT3 Negative_regulation of AKT1 1 1 0.09 0.49 0.32
95 INT337414 AKT2 Negative_regulation of AKT1 2 1 0.10 0.5 0.32
96 INT15685 Binding of PLAT and Serpine1 1 3 0.36 1.01 0.31
97 INT31043 Ghrh Positive_regulation of PLOD1 1 1 0.03 0 0.31
98 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 1 0.10 0 0.3
99 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 1 0.17 0 0.3
100 INT191240 SAE1 Regulation of Localization of INS 1 1 0.08 1.15 0.3
101 INT291249 Map3k8 Positive_regulation of INS Positive_regulation of AKT1 1 1 0.01 0.76 0.29
102 INT247083 Binding of F5 and PLAT 1 1 0.03 0.88 0.29
103 INT35079 CRH Negative_regulation of Localization of PLOD1 1 1 0.06 0 0.29
104 INT89911 PLOD1 Positive_regulation of Localization of PRL 1 1 0.12 0 0.29
105 INT89912 PLOD1 Positive_regulation of Localization of GH1 1 1 0.04 0 0.29
106 INT89897 PLOD1 Positive_regulation of Localization of POMC 1 1 0.13 0 0.29
107 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 1 0.01 0.76 0.29
108 INT109098 Binding of ABL2 and PON1 1 1 0.36 1.32 0.28
109 INT67768 NPL Positive_regulation of PLOD1 1 1 0.30 0 0.28
110 INT309298 Binding of NA and ST8SIA2 1 1 0.00 0 0.28
111 INT67769 Regulation of NPL Positive_regulation of PLOD1 1 1 0.17 0 0.28
112 INT44759 Negative_regulation of PLAT Positive_regulation of ODC1 1 1 0.27 0 0.27
113 INT44760 PLAT Positive_regulation of ODC1 1 1 0.29 0 0.27
114 INT125522 PLAT Regulation of Gene_expression of GDF15 1 1 0.08 0.46 0.26
115 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 1 0.07 0.44 0.26
116 INT125513 PLAT Positive_regulation of Transcription of GDF15 1 1 0.12 0.44 0.26
117 INT125517 Negative_regulation of PLAT Positive_regulation of GDF15 1 1 0.12 0.46 0.25
118 INT55641 Binding of CHRM1 and Adra2a 1 1 0.00 0 0.24
119 INT125519 Regulation of PLAT Positive_regulation of NFKB1 1 1 0.07 0.44 0.24
120 INT140376 TGM1 Positive_regulation of Rhoa 1 1 0.01 0 0.24
121 INT49697 ST8SIA4 Regulation of Prl 1 1 0.01 0.26 0.23
122 INT49693 ST8SIA4 Positive_regulation of ST8SIA4 Regulation of Prl 1 1 0.00 0.26 0.23
123 INT49686 Sms Negative_regulation of ST8SIA4 Regulation of Prl 1 1 0.00 0.27 0.23
124 INT37033 PLAT Negative_regulation of PLDN 1 1 0.08 0.07 0.23
125 INT49685 ST8SIA4 Regulation of Trh Positive_regulation of Prl 1 1 0.00 0.26 0.23
126 INT49694 ST8SIA4 Positive_regulation of Prl 1 1 0.01 0.26 0.23
127 INT37031 PLAT Positive_regulation of PLAT Negative_regulation of ODC1 1 1 0.53 0.07 0.23
128 INT265886 IGF1 Positive_regulation of AKT1 1 1 0.11 3.06 0.23
129 INT49684 Trh Positive_regulation of ST8SIA4 Regulation of Prl 1 1 0.01 0.26 0.23
130 INT316111 APC Negative_regulation of SAE1 1 1 0.04 1.21 0.22
131 INT224431 TNF Positive_regulation of Gene_expression of FBXO2 1 1 0.47 0.35 0.22
132 INT226902 Padi3 Regulation of Trp53 1 1 0.06 0.69 0.22
133 INT70082 Binding of APP and TGM1 1 1 0.00 1.22 0.22
134 INT224452 Il1 Positive_regulation of Gene_expression of FBXO2 1 1 0.37 0.35 0.22
135 INT193033 Binding of CHRM1 and EGF 1 1 0.01 1.96 0.22
136 INT295430 BRD2 Positive_regulation of PLOD1 1 1 0.02 0.33 0.22
137 INT35151 PLOD1 Regulation of PGR 1 1 0.09 0 0.21
138 INT35149 PLOD1 Regulation of GHRH 1 1 0.02 0 0.21
139 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 1 0.04 0.5 0.21
140 INT274578 Binding of ABL1 and PSTPIP1 1 1 0.07 1.55 0.21
141 INT120716 Binding of AKT1 and TEP1 1 1 0.05 0.46 0.21
142 INT35150 PLOD1 Regulation of LHB 1 1 0.09 0 0.21
143 INT316110 Binding of APC and SAE1 1 1 0.03 1.16 0.2
144 INT157083 Ghrl Regulation of Gene_expression of Ppt1 1 1 0.40 0 0.2
145 INT25053 Crh Regulation of PLOD1 1 1 0.11 0 0.19
146 INT32360 DBI Positive_regulation of Localization of PLOD1 1 1 0.05 0 0.19
147 INT121632 PTGER1 Positive_regulation of TGM1 1 1 0.00 0.67 0.19
148 INT197618 Binding of Esr1 and Ppt1 1 1 0.01 0 0.18
149 INT247082 Binding of PLAT and PTBP1 1 1 0.14 0.59 0.18
150 INT191241 SST Regulation of SAE1 1 1 0.05 0.89 0.18
151 INT121631 PDGFD Positive_regulation of TGM1 1 1 0.01 0.68 0.18
152 INT298192 EGFR Positive_regulation of AKT1 1 1 0.10 0.65 0.18
153 INT121582 AKT1 Regulation of Gene_expression of GDF15 1 1 0.21 0.4 0.18
154 INT318324 Binding of AKT1 and PRKCA 1 1 0.03 0.63 0.18
155 INT176133 AKT1 Regulation of BCL2 1 2 0.12 1.84 0.17
156 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 1 0.25 0.41 0.17
157 INT105334 PTGER1 Positive_regulation of Positive_regulation of AKT1 1 1 0.05 0.66 0.17
158 INT176134 AKT1 Regulation of Gene_expression of BIRC3 1 1 0.08 1.09 0.17
159 INT12521 Binding of PLOD1 and POMC 1 1 0.26 1.96 0.17
160 INT277013 PLAT Positive_regulation of Gene_expression of F13A1 1 1 0.02 0.31 0.17
161 INT25050 Crh Negative_regulation of PLOD1 1 1 0.11 0 0.17
162 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 1 0.03 0.19 0.17
163 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 1 0.05 0.91 0.16
164 INT295433 Binding of PLOD1 and SCN5A 1 1 0.07 0.25 0.16
165 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 1 0.00 0.48 0.15
166 INT248147 PLAT Positive_regulation of Gene_expression of CPOX 1 1 0.00 0.51 0.15
167 INT241844 Positive_regulation of GNRH1 Positive_regulation of Localization of PLOD1 1 1 0.13 0.08 0.15
168 INT70090 TGM1 Positive_regulation of Binding of Ache and 1 1 0.03 0.59 0.15
169 INT49681 ST8SIA4 Positive_regulation of Localization of GH1 1 1 0.01 0 0.15
170 INT188249 PLAT Positive_regulation of PLG 1 2 0.10 0.86 0.14
171 INT249829 CHI3L1 Positive_regulation of AKT1 1 1 0.47 0.69 0.14
172 INT298639 GDE1 Negative_regulation of AKT1 1 1 0.00 1.14 0.14
173 INT82802 Binding of ABL2 and POMC 1 1 0.00 0 0.14
174 INT211860 PLOD1 Regulation of AGRP 1 1 0.07 0.15 0.14
175 INT350204 Binding of CAP1 and QPCT 1 1 0.06 0 0.13
176 INT254133 PLEC Regulation of MCRS1 1 1 0.03 0.33 0.13
177 INT278583 Ppt1 Negative_regulation of Gene_expression of Atp6v1e1 1 1 0.05 0 0.13
178 INT302156 AKT1 Positive_regulation of E2F2 1 1 0.02 0.88 0.13
179 INT299310 RPTOR Positive_regulation of AKT1 1 1 0.30 0 0.12
180 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 1 2 0.03 1.32 0.11
181 INT27814 CD2AP Positive_regulation of PADI1 1 1 0.19 0.06 0.11
182 INT50903 Ppt1 Regulation of Tac4 1 1 0.18 0 0.11
183 INT105338 Prkaca Positive_regulation of AKT1 1 1 0.04 0.93 0.11
184 INT70084 Negative_regulation of Binding of APP and TGM1 1 1 0.00 0.61 0.11
185 INT350736 PRKDC Negative_regulation of CA2 1 1 0.02 0.16 0.11
186 INT70083 TGM1 Positive_regulation of Binding of APP and 1 1 0.00 0.61 0.11
187 INT133362 FABP6 Negative_regulation of LOX 1 1 0.01 0.08 0.11
188 INT294778 PAM Positive_regulation of Gene_expression of TLR2 1 1 0.01 0.41 0.11
189 INT350735 PRKDC Negative_regulation of ITPR3 1 1 0.01 0.16 0.11
190 INT302161 AKT1 Negative_regulation of CASP9 1 1 0.03 0.87 0.11
191 INT176130 AKT1 Regulation of Gene_expression of COX18 1 1 0.13 0.82 0.11
192 INT274583 Binding of ABL1 and PSTPIP2 1 1 0.06 0.79 0.11
193 INT27815 Regulation of CD2AP Positive_regulation of PADI1 1 1 0.11 0.06 0.11
194 INT50901 Ppt1 Regulation of Transcription of Tac4 1 1 0.18 0 0.11
195 INT65676 Binding of CGA and PLOD1 1 3 0.23 1.68 0.1
196 INT324702 PLOD1 Positive_regulation of CGA 1 1 0.03 1.1 0.1
197 INT226750 Hgs Positive_regulation of Tsg101 1 1 0.04 0.25 0.1
198 INT116449 POMC Negative_regulation of Localization of PLOD1 1 1 0.11 0 0.1
199 INT226708 Oprd1 Positive_regulation of Tsg101 1 1 0.00 0.3 0.1
200 INT226725 Gpbar1 Positive_regulation of Tsg101 1 1 0.03 0.3 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein modification process. They are ordered first by their pain relevance and then by number of times they were reported in protein modification process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT920 Localization of PLOD1 223 0.81 42.25 78.7
2 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03
3 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72
4 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51
5 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36
6 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4
7 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61
8 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87
9 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83
10 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06
11 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
12 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
13 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44
14 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95
15 INT4729 Positive_regulation of PPT1 19 0.67 7.11 17.83
16 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
17 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54
18 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52
19 INT4726 Negative_regulation of PPT1 15 0.57 10.09 14.17
20 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78
21 INT24684 Localization of PLAT 30 0.78 26.21 13.56
22 INT60865 Gene_expression of G2e3 20 0.73 2.1 12.76
23 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
24 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18
25 INT58775 Binding of G2e3 10 0.33 0.19 11.52
26 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29
27 INT175554 Binding of MCRS1 21 0.23 25.2 8.59
28 INT90674 Negative_regulation of LOX 56 0.57 38.01 8.58
29 INT24651 Positive_regulation of Transcription of Ppt1 12 0.47 2.88 8.42
30 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88
31 INT58774 Negative_regulation of G2e3 8 0.38 0.22 7.75
32 INT87623 Gene_expression of PPT1 9 0.75 5.32 7.65
33 INT5774 Regulation of Ppt1 22 0.60 4.97 7.1
34 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49
35 INT113961 Regulation of PPT1 6 0.26 3.87 6.09
36 INT4888 Positive_regulation of Gene_expression of Ppt1 9 0.54 2.78 5.83
37 INT55353 Negative_regulation of Positive_regulation of Ppt1 9 0.57 0.31 5.37
38 INT89304 Binding of ST8SIA2 12 0.35 0.93 5.23
39 INT51839 Positive_regulation of Localization of PLAT 5 0.49 7.09 4.92
40 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
41 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
42 INT50022 Positive_regulation of G2e3 10 0.42 0.47 3.72
43 INT55352 Regulation of Gene_expression of Ppt1 9 0.44 0.4 3.51
44 INT184894 Localization of MCRS1 9 0.47 10.04 3.31
45 INT14857 Negative_regulation of Gene_expression of Ppt1 7 0.42 1.16 3.3
46 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
47 INT1924 Regulation of PLAT 11 0.60 6.3 3.16
48 INT137961 Localization of Ppt1 1 0.64 2.89 3.09
49 INT4728 Negative_regulation of Positive_regulation of PPT1 2 0.42 0.29 3.07
50 INT69727 Gene_expression of QPCT 18 0.65 5.45 3.05
51 INT10136 Negative_regulation of PLAT 23 0.42 11.18 3.02
52 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
53 INT200670 Gene_expression of AKT2 25 0.75 16.25 3
54 INT305617 Positive_regulation of Gene_expression of MCRS1 1 0.05 7.16 2.91
55 INT25031 Negative_regulation of Gene_expression of PLOD1 14 0.54 3.86 2.89
56 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
57 INT10101 Binding of PLAT 24 0.36 12.62 2.78
58 INT68444 Gene_expression of CPE 9 0.76 4.6 2.59
59 INT60864 Regulation of G2e3 4 0.21 0.64 2.54
60 INT4725 Transcription of PPT1 2 0.69 0.59 2.42
61 INT15201 Positive_regulation of CHRM1 8 0.54 2.14 2.35
62 INT74237 Positive_regulation of Ppt1 3 0.49 2.92 2.32
63 INT12033 Binding of PLOD1 15 0.48 8.04 2.3
64 INT52785 Localization of G2e3 5 0.66 0.33 2.26
65 INT118791 Binding of AKT1 32 0.48 15.51 2.25
66 INT17617 Gene_expression of ABL2 8 0.75 2.73 2.25
67 INT45392 Regulation of CHRM1 3 0.26 0.52 2.25
68 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
69 INT36534 Negative_regulation of Positive_regulation of PLOD1 5 0.56 1.39 2.14
70 INT7974 Regulation of Gene_expression of PLOD1 6 0.42 0.41 1.99
71 INT7973 Positive_regulation of Regulation of PLOD1 5 0.42 0.42 1.99
72 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96
73 INT140822 Localization of PPT1 2 0.57 1.1 1.94
74 INT55640 Gene_expression of CHRM1 7 0.44 2.24 1.89
75 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
76 INT44723 Positive_regulation of ABL2 7 0.49 2.23 1.82
77 INT14862 Negative_regulation of Transcription of Ppt1 3 0.42 0 1.8
78 INT100563 Regulation of Binding of G2e3 1 0.24 0 1.79
79 INT104745 Positive_regulation of Binding of G2e3 1 0.05 0.07 1.77
80 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74
81 INT23932 Negative_regulation of ST8SIA2 4 0.22 1.26 1.73
82 INT73400 Negative_regulation of Wdyhv1 1 0.00 0 1.73
83 INT144292 Binding of Ppt1 9 0.37 2.02 1.71
84 INT147527 Regulation of Gene_expression of PPT1 1 0.44 1.17 1.69
85 INT85955 Negative_regulation of Localization of G2e3 2 0.48 0.05 1.63
86 INT25033 Negative_regulation of Negative_regulation of PLOD1 4 0.55 0.36 1.6
87 INT165347 Localization of CPE 2 0.55 0.59 1.56
88 INT2620 Regulation of TGM1 1 0.01 3.27 1.5
89 INT110749 Gene_expression of Ppt1 9 0.34 0.51 1.49
90 INT36698 Binding of CHRM3 5 0.48 1.97 1.49
91 INT106831 Negative_regulation of Regulation of CHRM1 1 0.15 0.16 1.49
92 INT340324 Regulation of Ppt1 1 0.13 1.17 1.47
93 INT83165 Binding of PPT1 1 0.36 0.75 1.45
94 INT37886 Positive_regulation of Positive_regulation of PLOD1 1 0.69 0 1.43
95 INT2619 Positive_regulation of TGM1 7 0.49 5.97 1.41
96 INT13730 Negative_regulation of CHRM1 5 0.35 1.78 1.41
97 INT112655 Negative_regulation of PAM 3 0.57 0.97 1.39
98 INT262876 Localization of ST8SIA2 2 0.16 1.41 1.39
99 INT79126 Gene_expression of Wdyhv1 1 0.07 0.8 1.36
100 INT4889 Regulation of Transcription of Ppt1 3 0.35 0.89 1.34
101 INT1651 Positive_regulation of Negative_regulation of PLOD1 4 0.46 0.49 1.33
102 INT53316 Localization of Ppt1 5 0.65 1.59 1.32
103 INT32039 Positive_regulation of CPE 3 0.37 1.92 1.32
104 INT224447 Gene_expression of FBXO2 7 0.75 7.33 1.31
105 INT63532 Positive_regulation of Positive_regulation of Ppt1 2 0.67 0 1.29
106 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
107 INT305616 Negative_regulation of Gene_expression of MCRS1 1 0.04 3.56 1.23
108 INT70088 Binding of TGM1 9 0.41 5.3 1.22
109 INT112498 Gene_expression of TGM1 18 0.55 10.76 1.21
110 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21
111 INT55351 Positive_regulation of Negative_regulation of Ppt1 3 0.45 0 1.19
112 INT76673 Regulation of G2E3 1 0.02 0 1.19
113 INT160054 Localization of AKT2 4 0.73 1.93 1.18
114 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17
115 INT135556 Localization of AKT1 38 0.69 12.78 1.17
116 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
117 INT105618 Binding of SEPHS1 4 0.27 5.62 1.14
118 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
119 INT205735 Regulation of Localization of PPT1 1 0.23 0 1.12
120 INT75698 Negative_regulation of Negative_regulation of Ppt1 1 0.42 1.01 1.11
121 INT75699 Negative_regulation of Ppt1 2 0.58 1.07 1.08
122 INT268379 Gene_expression of ARAF 22 0.16 9.34 1.07
123 INT87624 Positive_regulation of Gene_expression of PPT1 2 0.49 0.75 1.07
124 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06
125 INT71003 Regulation of CHRM3 4 0.07 2.03 1.06
126 INT98174 Positive_regulation of Gene_expression of ABL2 1 0.49 1.1 1.05
127 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02
128 INT262878 Gene_expression of ST8SIA2 7 0.39 4.7 1.01
129 INT68217 Positive_regulation of CHRM3 9 0.39 1.36 0.99
130 INT252562 Positive_regulation of Sae1 1 0.03 3.4 0.99
131 INT305620 Regulation of Positive_regulation of MCRS1 1 0.17 2.48 0.99
132 INT146786 Positive_regulation of Positive_regulation of PPT1 2 0.45 0.13 0.98
133 INT4914 Binding of Wdyhv1 1 0.01 0 0.98
134 INT58755 Binding of PAM 6 0.34 3.09 0.97
135 INT44446 Regulation of Regulation of PLOD1 3 0.38 1.85 0.97
136 INT70248 Positive_regulation of Positive_regulation of G2e3 1 0.13 0.17 0.94
137 INT171636 Negative_regulation of Gene_expression of PLAT 6 0.35 2.92 0.93
138 INT230779 Negative_regulation of Positive_regulation of MCRS1 2 0.04 3.78 0.92
139 INT309303 Positive_regulation of ST8SIA2 2 0.11 0.65 0.91
140 INT60458 Localization of G2E3 1 0.06 0 0.91
141 INT102733 Gene_expression of Ubr5 1 0.31 0.31 0.91
142 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88
143 INT113121 Negative_regulation of Binding of G2e3 1 0.07 0 0.88
144 INT73399 Negative_regulation of Negative_regulation of Wdyhv1 1 0.00 0 0.88
145 INT255622 Positive_regulation of PAM 7 0.18 4.89 0.87
146 INT29636 Localization of PAM 5 0.73 2.1 0.87
147 INT40639 Binding of CHRM1 2 0.26 0.43 0.87
148 INT271605 Regulation of Gene_expression of AKT2 1 0.44 0.81 0.87
149 INT55350 Regulation of Negative_regulation of Ppt1 2 0.60 0 0.86
150 INT263817 Regulation of Negative_regulation of LOX 1 0.33 2.36 0.86
151 INT58759 Positive_regulation of Binding of PAM 1 0.24 0.57 0.85
152 INT128143 Negative_regulation of Gene_expression of G2e3 4 0.09 0 0.82
153 INT33097 Negative_regulation of PHEX 3 0.14 0.41 0.82
154 INT157876 Gene_expression of Padi4 1 0.78 3.78 0.82
155 INT70933 Regulation of SEPHS1 3 0.37 2.56 0.81
156 INT354257 Regulation of Localization of PLAT 1 0.18 0.91 0.79
157 INT87734 Regulation of ARAF 4 0.23 2.44 0.76
158 INT159397 Regulation of Regulation of PPT1 1 0.26 0.54 0.76
159 INT125526 Gene_expression of PRKDC 5 0.58 4 0.74
160 INT157776 Localization of TGM1 2 0.39 2.52 0.74
161 INT134754 Positive_regulation of Gene_expression of PLAT 9 0.49 4.75 0.72
162 INT246524 Binding of QPCT 4 0.05 3.65 0.72
163 INT200669 Negative_regulation of AKT2 2 0.42 0.94 0.72
164 INT69452 Positive_regulation of SEPHS1 3 0.41 1.41 0.71
165 INT212265 Positive_regulation of Gene_expression of CPE 1 0.44 1.26 0.7
166 INT305419 Negative_regulation of Binding of ST8SIA2 1 0.22 0.1 0.69
167 INT299338 Negative_regulation of Regulation of AKT1 2 0.31 2.32 0.68
168 INT27818 Regulation of PADI1 7 0.34 3.77 0.66
169 INT19563 Gene_expression of CHRM3 6 0.58 2.68 0.66
170 INT39865 Regulation of Positive_regulation of PLOD1 2 0.27 0.71 0.66
171 INT192321 Regulation of LOX 2 0.33 2.72 0.65
172 INT59182 Gene_expression of G2E3 1 0.04 0 0.65
173 INT69283 Gene_expression of PHEX 25 0.75 7.81 0.64
174 INT276227 Gene_expression of UBL4A 9 0.20 7.12 0.64
175 INT4785 Gene_expression of PAM 6 0.58 3.47 0.64
176 INT166024 Protein_catabolism of AKT1 5 0.46 2.6 0.64
177 INT299324 Positive_regulation of QPCT 3 0.09 0.12 0.64
178 INT37862 Negative_regulation of Hma 2 0.38 0 0.64
179 INT122497 Gene_expression of UBE2S 2 0.58 0.8 0.64
180 INT289197 Localization of QPCT 3 0.15 0.53 0.62
181 INT73401 Binding of Wdyhv1 1 0.00 0 0.61
182 INT320096 Negative_regulation of SAE1 10 0.12 3.85 0.59
183 INT245648 Gene_expression of SEPHS1 5 0.49 4.53 0.59
184 INT171767 Positive_regulation of Gene_expression of MMP15 4 0.38 4.48 0.59
185 INT63533 Negative_regulation of Negative_regulation of Ppt1 1 0.29 0 0.59
186 INT123131 Negative_regulation of Negative_regulation of AKT1 6 0.42 3.23 0.58
187 INT90984 Transcription of PPT2 1 0.08 0.07 0.58
188 INT184345 Gene_expression of Tsg101 10 0.58 3.56 0.57
189 INT263823 Negative_regulation of Gene_expression of LOX 1 0.31 2.49 0.57
190 INT27816 Positive_regulation of PADI1 5 0.41 0.26 0.56
191 INT79894 Gene_expression of Sae1 2 0.11 1.65 0.54
192 INT299323 Negative_regulation of Gene_expression of QPCT 1 0.03 0.65 0.53
193 INT69176 Binding of UBA7 1 0.01 0.14 0.53
194 INT187721 Transcription of PLOD1 4 0.49 4.69 0.51
195 INT187714 Regulation of Negative_regulation of PLOD1 1 0.09 0 0.51
196 INT100099 Regulation of Positive_regulation of Ppt1 1 0.26 0 0.5
197 INT63249 Positive_regulation of Regulation of Ppt1 1 0.49 0 0.5
198 INT271604 Positive_regulation of Gene_expression of AKT2 2 0.49 0.22 0.47
199 INT11363 Regulation of Gene_expression of PLAT 1 0.27 0.87 0.46
200 INT102735 Positive_regulation of Ubr5 1 0.24 0.16 0.45
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