GOS:translation factor activity, nucleic acid binding

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This page displays the top molecular interactions and top single events that were mentioned in the literature for translation factor activity, nucleic acid binding. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for translation factor activity, nucleic acid binding. They are ordered first by their pain relevance and then by number of times they were reported for translation factor activity, nucleic acid binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to translation factor activity, nucleic acid binding Documents TM Confidence Disease Relevance Pain Relevance
1 INT97635 ABCF1 Positive_regulation of Localization of CCR1 1 1 0.05 0.51 0.55
2 INT182813 EEF1A2 Negative_regulation of ITGAL 1 1 0.10 1.53 0.51
3 INT97636 ABCF1 Positive_regulation of Localization of CXCR1 1 1 0.35 0.45 0.51
4 INT97634 ABCF1 Positive_regulation of Localization of CCL16 1 1 0.11 0.44 0.51
5 INT38549 Binding of VIP and EIF1 1 1 0.06 0 0.36
6 INT75643 NCOR2 Positive_regulation of Positive_regulation of EIF2B3 1 1 0.00 0 0.33
7 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 1 0.02 0 0.33
8 INT182817 EEF1A2 Positive_regulation of BMP2 1 1 0.26 1.62 0.28
9 INT246576 EEF1A2 Negative_regulation of Negative_regulation of NOSTRIN 1 1 0.04 0.63 0.24
10 INT144588 Binding of EEF1A2 and pad 1 1 0.36 1.34 0.24
11 INT182816 EEF1A2 Negative_regulation of CRP 1 1 0.28 1.84 0.21
12 INT76196 Binding of HTR1A and EIF2B3 1 1 0.06 0 0.17
13 INT173499 EEF1A2 Negative_regulation of Cpox 1 1 0.07 0.39 0.14
14 INT173498 EEF1A2 Regulation of Cpox 1 1 0.04 0.39 0.14
15 INT308225 Alb Positive_regulation of Binding of EIF4G2 and 1 1 0.02 0.33 0.09
16 INT244452 CS Positive_regulation of Phosphorylation of EIF2S2 1 1 0.21 2.07 0.09
17 INT203419 Binding of EIF4A1 and Gtf3a 1 1 0.00 0.5 0.07
18 INT244464 EIF2AK3 Positive_regulation of Positive_regulation of EIF2S2 1 1 0.17 0.37 0.04
19 INT244463 EIF2AK3 Regulation of Phosphorylation of EIF2S2 1 1 0.09 0.37 0.04
20 INT211779 Binding of EIF4G1 and NTSR1 1 1 0.02 0 0
21 INT186905 EIF1 Regulation of Gene_expression of IL8 1 1 0.07 0 0
22 INT186904 EIF1 Positive_regulation of Localization of IL8 1 1 0.06 0 0
23 INT244475 Binding of CS and Positive_regulation of EIF2S2 1 1 0.11 0.07 0
24 INT338179 EEF1D Regulation of CDCP1 1 1 0.00 1.43 0
25 INT244460 Binding of CS and Positive_regulation of Positive_regulation of EIF2S2 1 1 0.13 0.06 0
26 INT334491 Binding of GCN1L1 and Mgst1 1 1 0.08 0 0
27 INT182818 EEF1A2 Negative_regulation of STAR 1 1 0.01 1.48 0
28 INT186906 EIF1 Positive_regulation of Localization of LDHA 1 1 0.03 0 0
29 INT186902 EIF1 Positive_regulation of Gene_expression of IL8 1 1 0.08 0 0
30 INT244468 CS Positive_regulation of EIF2S2 1 1 0.16 0.43 0
31 INT186907 EIF1 Regulation of DEFB1 1 1 0.00 0 0
32 INT244467 Negative_regulation of CS Positive_regulation of EIF2S2 1 1 0.11 0.14 0
33 INT186908 EIF1 Positive_regulation of Transcription of IL8 1 1 0.06 0 0
34 INT283711 Sox11 Regulation of 4930579C15Rik 1 1 0.28 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for translation factor activity, nucleic acid binding. They are ordered first by their pain relevance and then by number of times they were reported in translation factor activity, nucleic acid binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75645 Binding of EIF2B3 10 0.07 0.21 4.9
2 INT75647 Positive_regulation of Binding of EIF2B3 3 0.07 0.11 1.42
3 INT97639 Localization of ABCF1 1 0.51 0.78 1
4 INT186924 Gene_expression of EIF1 25 0.08 2.64 0.97
5 INT157293 Gene_expression of EEF1A2 4 0.78 4.07 0.77
6 INT55885 Positive_regulation of EIF1 3 0.43 1.17 0.71
7 INT62301 Regulation of EIF4E2 2 0.19 3.2 0.71
8 INT75646 Positive_regulation of EIF2B3 2 0.06 0.11 0.68
9 INT123741 Negative_regulation of EIF4G3 1 0.17 0.15 0.6
10 INT97641 Negative_regulation of Localization of ABCF1 1 0.27 0.44 0.51
11 INT186912 Protein_catabolism of EIF1 1 0.10 1.88 0.39
12 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
13 INT86395 Negative_regulation of Binding of EIF2B3 1 0.05 0.06 0.3
14 INT176895 Negative_regulation of EEF1A2 3 0.41 0.85 0.29
15 INT176898 Binding of EEF1A2 2 0.36 0.98 0.21
16 INT244524 Phosphorylation of EIF2S2 1 0.49 11.33 0.2
17 INT157295 Positive_regulation of Gene_expression of EEF1A2 1 0.70 1.57 0.19
18 INT164567 Negative_regulation of EIF1 2 0.01 0.19 0.18
19 INT186911 Regulation of EIF1 1 0.03 0 0.16
20 INT304894 Gene_expression of EIF4E2 1 0.07 0.81 0.16
21 INT37694 Protein_catabolism of EIF4G3 1 0.02 0 0.15
22 INT353246 Gene_expression of EIF4G1 1 0.06 1.23 0.14
23 INT260700 Regulation of Gene_expression of EIF1 1 0.01 0 0.14
24 INT244563 Positive_regulation of EIF2S2 1 0.41 7.67 0.13
25 INT186917 Localization of EIF1 1 0.08 0.41 0.12
26 INT244559 Negative_regulation of Phosphorylation of EIF2S2 1 0.35 1.56 0.12
27 INT244566 Positive_regulation of Phosphorylation of EIF2S2 1 0.41 2.69 0.09
28 INT157292 Positive_regulation of EEF1A2 1 0.70 0.8 0.09
29 INT308214 Binding of EIF4G2 1 0.35 0.32 0.08
30 INT283695 Binding of Sox11 1 0.32 0.18 0.08
31 INT157294 Regulation of EEF1A2 1 0.45 0.76 0.08
32 INT244544 Positive_regulation of Positive_regulation of EIF2S2 1 0.28 0.67 0.07
33 INT283696 Localization of Sox11 1 0.65 0.37 0.05
34 INT244535 Negative_regulation of Positive_regulation of EIF2S2 1 0.35 0.54 0.03
35 INT244556 Regulation of Positive_regulation of EIF2S2 1 0.27 0.59 0.03
36 INT336403 Transcription of SOX11 1 0.24 0.84 0.03
37 INT300037 Localization of EEF1A2 2 0.73 2.02 0
38 INT186929 Positive_regulation of Gene_expression of EIF1 1 0.05 0.21 0
39 INT211840 Protein_catabolism of EIF4G1 1 0.35 0.13 0
40 INT211836 Binding of EIF4G1 1 0.12 0.07 0
41 INT244568 Positive_regulation of Gene_expression of EIF2S2 1 0.41 12.82 0
42 INT186927 Transcription of EIF1 1 0.07 0 0
43 INT283699 Positive_regulation of Sox11 1 0.35 0.62 0
44 INT351113 Negative_regulation of Negative_regulation of EIF1AX 1 0.41 1.09 0
45 INT301996 Binding of Eif4g2 1 0.10 0.29 0
46 INT244541 Negative_regulation of EIF2S2 1 0.25 0 0
47 INT244509 Regulation of Gene_expression of EIF2S2 1 0.27 1.14 0
48 INT244562 Gene_expression of EIF2S2 1 0.46 23.74 0
49 INT244511 Regulation of EIF2S2 1 0.37 4.46 0
50 INT334488 Binding of GCN1L1 1 0.24 0 0
51 INT351124 Gene_expression of EIF1AX 1 0.75 0.99 0
52 INT172489 Positive_regulation of Transcription of EIF5 1 0.35 0.11 0
53 INT351120 Regulation of Negative_regulation of EIF1AX 1 0.44 1.09 0
54 INT252752 Phosphorylation of MTIF2 1 0.06 1.38 0
55 INT244499 Binding of EIF2S2 1 0.22 0.33 0
56 INT351125 Negative_regulation of EIF1AX 1 0.57 1.08 0
57 INT302018 Positive_regulation of GCN1L1 1 0.04 0 0
58 INT172482 Positive_regulation of EIF5 1 0.35 0.11 0
59 INT244503 Regulation of Regulation of EIF2S2 1 0.27 0.16 0
60 INT172485 Transcription of EIF5 1 0.48 0.11 0
61 INT298915 Binding of EEF1D 1 0.47 0.06 0
62 INT179189 Gene_expression of EIF4G3 1 0.40 0.26 0
63 INT186928 Binding of EIF1 1 0.04 0.22 0
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