GOS:unfolded protein binding

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This page displays the top molecular interactions and top single events that were mentioned in the literature for unfolded protein binding. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for unfolded protein binding. They are ordered first by their pain relevance and then by number of times they were reported for unfolded protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Genes linked to unfolded protein binding Documents TM Confidence Disease Relevance Pain Relevance
1 INT85042 Binding of CCT6A and MAX 1 1 0.00 0 3.13
2 INT187175 Binding of BSG and PPIA 1 1 0.14 2.23 1.64
3 INT116628 St13 Regulation of Positive_regulation of P9Ehs1 1 1 0.00 0 1.25
4 INT42806 Binding of CCT6A and PENK 1 1 0.02 0 1.23
5 INT94091 Binding of Pnoc and Tbce 1 1 0.03 0.19 1.19
6 INT161011 Binding of Cpe and St13 1 2 0.03 0.61 1.07
7 INT85040 Positive_regulation of Binding of CCT6A and MAX 1 1 0.00 0 1.06
8 INT227545 Hspa9 Positive_regulation of Prep 1 1 0.18 0.59 0.96
9 INT129881 Binding of Calr and Cbll1 1 1 0.00 0.58 0.84
10 INT56459 ADRA2C Positive_regulation of Localization of AHSP 1 1 0.23 0 0.78
11 INT258798 Binding of NR3C1 and HSP90AA1 1 1 0.01 1.09 0.78
12 INT316673 Binding of CALR and LRP1 1 1 0.39 1.89 0.74
13 INT267888 St13 Positive_regulation of Insrr 1 1 0.00 0.07 0.64
14 INT318981 Binding of CALR and GOPC 1 1 0.03 0.77 0.64
15 INT118083 Aip Negative_regulation of Phosphorylation of APP 2 1 0.00 0.75 0.62
16 INT227544 Hspa9 Regulation of Gene_expression of Prep 1 1 0.15 0.57 0.61
17 INT165844 Binding of ATF4 and HSP90AB1 1 1 0.15 0.34 0.61
18 INT267887 St13 Positive_regulation of Localization of Insrr 1 1 0.00 0 0.58
19 INT314208 Trap1 Positive_regulation of Mapk14 1 1 0.10 0.66 0.57
20 INT27871 Binding of FCGR1B and HSPD1 2 1 0.01 1.93 0.56
21 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 2 1 0.01 1.93 0.56
22 INT271888 Binding of DRD2 and DNAJC7 1 1 0.14 0.36 0.55
23 INT77508 ST13 Negative_regulation of Gene_expression of CD9 1 1 0.09 0.5 0.54
24 INT267889 St13 Regulation of Insrr 1 1 0.00 0.43 0.54
25 INT299766 APCS Positive_regulation of Gene_expression of Cd80 1 1 0.04 0.86 0.5
26 INT299767 APCS Positive_regulation of Gene_expression of Cd86 1 1 0.07 0.86 0.5
27 INT299764 APCS Positive_regulation of Cd86 1 1 0.02 0.86 0.5
28 INT299765 APCS Positive_regulation of Cd80 1 1 0.04 0.85 0.49
29 INT75728 PCDHB17 Positive_regulation of CCT6A 1 1 0.00 0.06 0.44
30 INT314263 Binding of CPOX and PTGES3 1 1 0.01 1.7 0.44
31 INT254120 Aliq1 Positive_regulation of Tbce 1 1 0.00 0.68 0.43
32 INT85037 Binding of Cct2 and Chrna3 1 1 0.00 0.15 0.38
33 INT161005 Binding of Gfap and St13 1 1 0.15 0.52 0.37
34 INT161010 Gfap Regulation of St13 1 1 0.05 0.52 0.37
35 INT316675 Binding of CALR and SFTPD 1 1 0.35 0.96 0.37
36 INT161002 Binding of Itgam and St13 1 1 0.11 0.52 0.37
37 INT161008 Itgam Regulation of St13 1 1 0.08 0.52 0.37
38 INT106511 Binding of Cpox and Ptges3 2 2 0.01 0.7 0.36
39 INT93694 Binding of Hspa8 and Ptgs1 2 1 0.30 0.79 0.36
40 INT67000 Dnajc3 Negative_regulation of Negative_regulation of Penk 1 1 0.00 0.54 0.34
41 INT188521 Binding of Hsp90aa1 and Ptges3 3 1 0.02 0.61 0.33
42 INT39594 TPO Positive_regulation of CALR 1 1 0.30 0.91 0.32
43 INT318323 Binding of GRB2 and HSPA5 1 1 0.34 0.28 0.31
44 INT99154 Binding of DBP and SIL1 1 1 0.02 0.16 0.31
45 INT180246 Binding of Tbca and Uchl1 1 1 0.00 0.47 0.27
46 INT293708 Binding of TNF and Trap1 1 1 0.00 0.94 0.27
47 INT111909 Binding of HSPD1 and CCT4 3 1 0.29 0.48 0.25
48 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 1 0.03 0.73 0.25
49 INT111908 Binding of HSPD1 and AP4B1 2 1 0.03 0.48 0.25
50 INT287794 Binding of IGHG3 and AIP 1 1 0.05 2.8 0.24
51 INT100279 TXN Negative_regulation of Gene_expression of HSP90B2P 1 1 0.13 0.3 0.24
52 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 1 0.04 0.32 0.24
53 INT333927 GLUL Positive_regulation of HSPA5 1 1 0.17 0.78 0.24
54 INT175324 Hsp90b1 Positive_regulation of TLR2 1 1 0.00 0.65 0.23
55 INT100281 POMC Negative_regulation of Gene_expression of HSP90B2P 1 1 0.24 0.29 0.23
56 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 1 0.02 0.66 0.23
57 INT267885 Binding of Insrr and St13 1 1 0.00 0.09 0.23
58 INT289955 Binding of APCS and KLF1 1 1 0.00 0.21 0.23
59 INT269066 Binding of Hspa8 and Il6 2 1 0.00 0.74 0.23
60 INT192864 Binding of Hspa5 and Mela 1 1 0.25 1.06 0.22
61 INT180247 Binding of Gad1 and Tbca 1 1 0.02 0.22 0.22
62 INT129594 St13 Positive_regulation of Positive_regulation of Tnf 1 1 0.26 0.85 0.21
63 INT254121 Binding of Tbce and Aliq1 1 1 0.00 0.69 0.2
64 INT256706 Binding of Hsp90b1 and Wfs1 1 1 0.43 5.02 0.2
65 INT79521 Ptger1 Negative_regulation of Positive_regulation of Tbce 1 1 0.00 0.57 0.2
66 INT224086 Binding of Agtr1a and Hspa8 2 1 0.00 0.1 0.19
67 INT324822 Binding of Cd24a and Hsp90aa1 1 1 0.10 0.71 0.19
68 INT231763 Binding of HSPD1 and TLR2 2 1 0.12 2 0.19
69 INT251492 Binding of HSPD1 and SOD1 2 1 0.02 1.45 0.18
70 INT132265 Binding of SGCG and Canx 1 1 0.04 0.24 0.18
71 INT314269 Binding of PTGES and PTGES3 1 1 0.12 0.68 0.18
72 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 1 0.00 0.65 0.18
73 INT263361 Gars Regulation of St13 1 1 0.03 0.2 0.17
74 INT224101 Binding of Hspa8 and Agtr1a Negative_regulation of Agtr1a 2 1 0.00 0.09 0.17
75 INT339252 Positive_regulation of GNRH1 Positive_regulation of Localization of SCG5 1 1 0.51 0 0.17
76 INT93693 Positive_regulation of Binding of Hspa8 and Ptgs1 2 1 0.31 0.38 0.17
77 INT324820 Hsp90b1 Positive_regulation of Tlr2 1 1 0.16 0.42 0.17
78 INT130690 Gene_expression of HSPA5 Negative_regulation of Positive_regulation of DDIT3 1 1 0.21 0.58 0.17
79 INT165751 Hspa8 Positive_regulation of Protein_catabolism of Rgs9 2 1 0.50 0.17 0.17
80 INT224126 Binding of Hspa8 and Agtr1a 2 1 0.00 0.09 0.17
81 INT129592 St13 Positive_regulation of Protein_catabolism of Stat3 1 1 0.26 0.84 0.16
82 INT129593 St13 Positive_regulation of Positive_regulation of Stat3 1 1 0.28 0.84 0.16
83 INT231765 Binding of HSPD1 and TLR4 2 1 0.13 1.94 0.16
84 INT354114 Binding of CALR and SST 1 1 0.01 0.1 0.16
85 INT316769 Binding of H2-K1 and Hspa9 1 1 0.08 1.02 0.15
86 INT228757 Hspa9 Regulation of Ccl24 1 1 0.06 0.31 0.15
87 INT17014 AHSP Positive_regulation of Positive_regulation of RTCA 1 1 0.07 1.11 0.14
88 INT342518 HSP90B1 Positive_regulation of Gene_expression of TLR4 1 1 0.04 0.4 0.13
89 INT324837 Hspd1 Positive_regulation of Binding of Tlr4 and Hsp90b1 1 1 0.05 0.36 0.13
90 INT324807 Binding of Tlr4 and Hsp90b1 1 1 0.10 0.36 0.13
91 INT342520 HSP90B1 Positive_regulation of Gene_expression of TLR2 1 1 0.06 0.4 0.13
92 INT228746 Hspa9 Negative_regulation of Positive_regulation of Hand2 1 1 0.11 0.31 0.11
93 INT259636 Binding of Tbce and COPD 1 1 0.04 1 0.11
94 INT192358 CRP Regulation of Positive_regulation of HSPD1 2 1 0.15 2.46 0.1
95 INT167040 Binding of Aip and Drb1 1 1 0.10 0.54 0.1
96 INT167041 Binding of HLA-A and Aip 1 1 0.02 0.54 0.1
97 INT192352 CRP Regulation of HSPD1 2 1 0.15 2.46 0.1
98 INT160159 Gene_expression of CYP2C9 Positive_regulation of HSP90B2P 1 1 0.13 0.53 0.09
99 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 1 0.05 1.18 0.09
100 INT294608 Binding of Serpinh1 and Col5a1 1 1 0.03 0.45 0.09
101 INT230856 Binding of HSP90AA1 and NOS1 1 1 0.04 1.17 0.09
102 INT230065 Binding of TOR1A and HLA-DOA 1 1 0.00 1.65 0.09
103 INT145987 Binding of CTLA4 and Aip 2 1 0.08 0.61 0.09
104 INT192860 Binding of Calr and Esr1 1 1 0.06 0.67 0.08
105 INT289957 Binding of APCS and CD58 1 1 0.04 0.35 0.08
106 INT326574 Binding of Akt1 and Hsp90ab1 1 1 0.13 0.17 0.08
107 INT135732 Binding of CD79A and HSP90B2P 1 1 0.42 1.38 0.08
108 INT192862 Binding of Esr1 and Hspa5 1 1 0.08 0.68 0.08
109 INT227547 Hspa9 Regulation of Gene_expression of Rnpep 1 1 0.02 0.31 0.08
110 INT215880 Car2 Regulation of Hspa5 1 1 0.09 0.66 0.08
111 INT227546 Hspa9 Regulation of Rnpep 1 1 0.01 0.31 0.08
112 INT352217 Tlr4 Positive_regulation of Binding of Tbce and 1 1 0.03 0.8 0.07
113 INT312645 Binding of DNAJA3 and Musk 1 1 0.08 0.96 0.07
114 INT267214 Hspb8 Negative_regulation of Cryab 1 1 0.32 1.56 0.06
115 INT166732 BATF Negative_regulation of PPIA 1 1 0.05 1.45 0.06
116 INT324865 Tbce Positive_regulation of Gene_expression of ecs 1 1 0.06 0.35 0.05
117 INT228736 Hspa9 Negative_regulation of Gene_expression of Ccr3 1 1 0.20 0.31 0.05
118 INT336991 Binding of PDCL and DNAJC14 1 1 0.04 0 0.05
119 INT336992 Binding of PDC and DNAJC14 1 1 0.06 0 0.05
120 INT284448 Il11 Positive_regulation of Hspa8 2 1 0.04 0.42 0.05
121 INT228745 Hspa9 Negative_regulation of Gene_expression of Cd8a 1 1 0.03 0.31 0.05
122 INT293494 Sfpi1 Regulation of Negative_regulation of Hsp90aa1 1 1 0.04 0.23 0.05
123 INT308432 Binding of PDE4A and Aip 2 1 0.05 3.1 0.05
124 INT228754 Hspa9 Negative_regulation of Gene_expression of Cd4 1 1 0.19 0.31 0.05
125 INT335702 Esr1 Regulation of Calr 1 1 0.03 0 0.04
126 INT329015 Binding of APCS and SRGN 1 1 0.08 1.14 0.04
127 INT334107 Binding of APC and APCS 1 1 0.16 1.52 0.04
128 INT215876 Atf4 Regulation of Hspa5 1 1 0.22 0.43 0.04
129 INT181168 Binding of CD79A and TAPBP 1 1 0.10 0.7 0.04
130 INT352216 Binding of Tlr4 and Tbce 1 1 0.01 0.3 0.04
131 INT328301 GHRH Positive_regulation of SCG5 1 1 0.24 0.13 0.04
132 INT350434 Negative_regulation of HSP90AA1 Positive_regulation of Gene_expression of ATF3 1 1 0.32 2.44 0.04
133 INT335703 Esr1 Regulation of Localization of Calr 1 1 0.03 0 0.04
134 INT199406 Binding of CYP3A4 and PPIB 1 1 0.40 0 0.04
135 INT225027 Binding of TAPBP and TRERF1 1 1 0.33 0 0.04
136 INT326571 Binding of Hsf1 and Hsp90ab1 1 1 0.16 1.19 0.03
137 INT234196 ERBB2 Positive_regulation of Negative_regulation of HSP90AA1 1 1 0.19 0.79 0.03
138 INT269838 Binding of Hsp90b1 and Tlr2 1 1 0.26 1.75 0.03
139 INT342512 Hsp90b1 Positive_regulation of Gene_expression of HSP90B1 2 1 0.24 0.62 0.03
140 INT326570 Hsp90ab1 Regulation of Csprs 1 1 0.08 1.17 0.03
141 INT234195 HSP90AA1 Regulation of AKT1 1 1 0.14 0.65 0.03
142 INT221243 Binding of Hspa9 and Ppif 1 1 0.01 0.67 0.03
143 INT317318 Binding of Gfm1 and Trap1 1 1 0.01 0.83 0
144 INT270116 DMD Regulation of St13 1 1 0.01 0.09 0
145 INT233273 Binding of Emx2 and Tbca 1 1 0.01 0.34 0
146 INT192354 Binding of CRP and HSPD1 2 1 0.12 1.28 0
147 INT247576 Binding of Hif1a and Vbp1 1 1 0.01 0.6 0
148 INT342730 Pink1 Positive_regulation of Phosphorylation of Trap1 1 1 0.17 0.98 0
149 INT350432 HSP90AA1 Positive_regulation of Gene_expression of ATF3 1 1 0.32 1.27 0
150 INT292679 GOPC Positive_regulation of HSP90AA1 1 1 0.01 0.1 0
151 INT308425 Binding of Pde2a and Aip 2 1 0.04 1.37 0
152 INT256703 Negative_regulation of Hsp90b1 Positive_regulation of Wfs1 1 1 0.42 0.24 0
153 INT181169 TAPBP Negative_regulation of MALT1 1 1 0.00 0.48 0
154 INT342737 Pink1 Positive_regulation of HTRA2 1 1 0.29 0.58 0
155 INT244462 XBP1 Regulation of Gene_expression of DNAJB11 1 1 0.11 0 0
156 INT172118 Binding of HSPA1B and C4b 1 1 0.39 0.92 0
157 INT316774 Hsp90b1 Positive_regulation of Localization of Ddit3 1 1 0.12 0.17 0
158 INT181167 TAPBP Negative_regulation of CD79A 1 1 0.11 0.48 0
159 INT256700 Negative_regulation of Binding of Hsp90b1 and Wfs1 1 1 0.52 0 0
160 INT303088 Akt1 Negative_regulation of Gene_expression of CANX 1 1 0.10 0.28 0
161 INT244454 Binding of EIF2AK3 and SIL1 1 1 0.05 0.41 0
162 INT312642 DNAJA3 Positive_regulation of Musk 1 1 0.08 0.37 0
163 INT336994 CALR Negative_regulation of ESR1 1 1 0.04 0 0
164 INT342728 Pink1 Positive_regulation of Trap1 1 1 0.17 0.98 0
165 INT335705 Binding of ITGA4 and Calr 1 1 0.01 0.43 0
166 INT316770 Hsp90b1 Positive_regulation of Ddit3 1 1 0.12 0.17 0
167 INT293492 Hsp90aa1 Regulation of Gene_expression of Sfpi1 1 1 0.04 0.1 0
168 INT351732 SSD Regulation of CALR 1 1 0.01 2.95 0
169 INT340914 Binding of Hsp90aa1 and Fkbp6 1 1 0.12 0.26 0
170 INT307306 Gene_expression of COMP Positive_regulation of CALR 1 1 0.27 0.99 0
171 INT221249 Hspa9 Negative_regulation of Gene_expression of Ros1 1 1 0.01 0.91 0
172 INT303089 Akt1 Negative_regulation of CANX 1 1 0.10 0.28 0
173 INT244473 ATF6 Regulation of Gene_expression of DNAJB11 1 1 0.10 0 0
174 INT350430 Negative_regulation of HSP90AA1 Positive_regulation of ATF3 1 1 0.32 3.11 0
175 INT307305 Gene_expression of COMP Positive_regulation of Positive_regulation of CALR 1 1 0.27 0.41 0
176 INT206943 Hspa5 Positive_regulation of Atf4 1 1 0.47 0.62 0
177 INT333928 Binding of CALR and ESR1 1 1 0.09 0.09 0
178 INT293493 Hsp90aa1 Regulation of Gene_expression of Erbb2 1 1 0.38 0.1 0
179 INT351733 CALR Positive_regulation of ROS1 1 1 0.03 0.3 0
180 INT342736 Pink1 Positive_regulation of Phosphorylation of HTRA2 1 1 0.29 0.58 0
181 INT161823 Positive_regulation of Binding of Igha and Aip 2 1 0.01 0.16 0
182 INT346755 Atf6 Positive_regulation of Hsp90b1 1 1 0.00 0 0
183 INT234214 Binding of HSP90AA1 and Tpt1 1 1 0.04 0.42 0
184 INT351730 CALR Positive_regulation of Positive_regulation of ROS1 1 1 0.02 0.72 0
185 INT234215 Binding of HSP90AA1 and Tpt1 Positive_regulation of HSP90AA1 1 1 0.03 0.17 0
186 INT161822 Binding of Igha and Aip 2 1 0.00 0.16 0
187 INT256701 Binding of Hsp90aa1 and Hsp90b1 2 1 0.12 0.34 0
188 INT282743 Hsp90aa1 Positive_regulation of Kit 1 1 0.22 0.54 0
189 INT253630 Binding of HNRNPA1 and Npm1 1 1 0.00 0.19 0
190 INT340913 Fkbp6 Negative_regulation of Binding of Hsp90aa1 and 1 1 0.14 0.26 0
191 INT186401 Binding of MKKS and MKS1 1 1 0.09 0.07 0
192 INT317307 Binding of Hsp90aa1 and Pink1 1 1 0.12 0.56 0
193 INT350503 Binding of HSP90AA1 and JAK2 1 1 0.06 1.39 0
194 INT181165 TAPBP Regulation of Gene_expression of CD79A 1 1 0.07 0.35 0
195 INT267215 Binding of Cryab and Hspb1 1 1 0.25 7.19 0
196 INT100265 Hsp90aa1 Regulation of Positive_regulation of Esrrb 1 1 0.10 0.1 0
197 INT262215 Binding of Nr1i2 and Dnajc7 1 1 0.08 0.26 0
198 INT263584 Hspa5 Positive_regulation of Myo1b 1 1 0.00 1.02 0
199 INT340917 Binding of Ptges3 and Ptplad1 1 1 0.14 0.17 0
200 INT340915 Binding of Hsp90aa1 and Ptplad1 1 1 0.12 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for unfolded protein binding. They are ordered first by their pain relevance and then by number of times they were reported in unfolded protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36262 Positive_regulation of Tbce 35 0.49 28.79 14.33
2 INT105754 Regulation of St13 8 0.28 0.75 11.41
3 INT60500 Negative_regulation of Tbce 21 0.41 13.3 11.1
4 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
5 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37
6 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59
7 INT129585 Gene_expression of St13 17 0.59 4.46 9.3
8 INT42707 Gene_expression of Tbce 24 0.65 12.92 7.93
9 INT22205 Gene_expression of CCT6A 7 0.29 0.86 6.63
10 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
11 INT57721 Localization of CCT6A 2 0.16 3.12 5.88
12 INT3306 Localization of Tbce 16 0.12 8.24 5.71
13 INT232663 Positive_regulation of CCT6A 1 0.13 3.08 5.27
14 INT121801 Binding of Aip 18 0.36 24.1 5.26
15 INT135436 Gene_expression of Hspa9 31 0.62 14.75 5.2
16 INT10474 Regulation of Tbce 6 0.22 4.18 5.11
17 INT55434 Positive_regulation of Gene_expression of HSP90B2P 14 0.38 10.91 4.83
18 INT37168 Positive_regulation of APCS 22 0.67 9.61 4.59
19 INT17020 Localization of AHSP 11 0.80 3.82 4.34
20 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23
21 INT84700 Positive_regulation of HSP90B2P 34 0.67 30.22 4.07
22 INT95877 Gene_expression of St13 24 0.49 11.18 3.95
23 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91
24 INT120062 Binding of AIP 4 0.42 28.86 3.91
25 INT227519 Positive_regulation of Hspa9 22 0.55 16.38 3.83
26 INT160994 Negative_regulation of St13 9 0.20 4.83 3.71
27 INT3564 Positive_regulation of Aip 11 0.58 15.38 3.62
28 INT32517 Positive_regulation of LRPAP1 13 0.49 7.4 3.44
29 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31
30 INT227523 Localization of Hspa9 9 0.60 5.26 3.18
31 INT244512 Positive_regulation of Gene_expression of HSP90B1 2 0.30 12.08 3.12
32 INT68675 Regulation of APCS 10 0.62 7.61 3.01
33 INT143763 Binding of St13 2 0.36 0.72 3.01
34 INT117121 Gene_expression of Hspa8 7 0.65 4.92 2.94
35 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88
36 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
37 INT42811 Binding of CCT6A 4 0.07 0 2.78
38 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
39 INT129589 Positive_regulation of St13 6 0.38 3 2.61
40 INT102729 Gene_expression of APCS 20 0.65 8.86 2.52
41 INT228047 Negative_regulation of Gene_expression of Tbce 4 0.06 2.33 2.48
42 INT106513 Gene_expression of Ptges3 7 0.73 3.57 2.42
43 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
44 INT228048 Positive_regulation of Positive_regulation of Tbce 3 0.05 2.47 2.35
45 INT99157 Binding of SIL1 8 0.35 2.66 2.33
46 INT18853 Negative_regulation of APCS 13 0.57 4.51 2.3
47 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
48 INT222088 Gene_expression of Dnajb1 11 0.65 3.37 2.18
49 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
50 INT84702 Positive_regulation of Positive_regulation of HSP90B2P 6 0.49 1.34 2.03
51 INT195968 Positive_regulation of Gene_expression of Hsp90b1 10 0.49 5.21 2.02
52 INT70526 Binding of CALR 11 0.35 7.09 1.97
53 INT21941 Regulation of CALR 7 0.53 3.88 1.96
54 INT164254 Gene_expression of Dnaja3 1 0.57 1.1 1.83
55 INT61939 Negative_regulation of Positive_regulation of Tbce 5 0.06 4.82 1.82
56 INT228052 Positive_regulation of Negative_regulation of Tbce 1 0.05 1.56 1.82
57 INT81924 Positive_regulation of HSPA1B 1 0.03 1.47 1.82
58 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81
59 INT20394 Binding of Tbce 12 0.06 5.47 1.78
60 INT27881 Binding of HSPD1 10 0.31 9.2 1.78
61 INT64762 Gene_expression of Uggt1 2 0.71 0 1.78
62 INT261509 Localization of ST13 3 0.01 1.36 1.77
63 INT19265 Negative_regulation of Localization of AHSP 3 0.59 0.62 1.69
64 INT150215 Localization of LRPAP1 1 0.73 1.52 1.62
65 INT92311 Regulation of SIL1 7 0.44 6.2 1.61
66 INT43425 Positive_regulation of Hspa9 2 0.13 1 1.61
67 INT98687 Gene_expression of Calr 38 0.61 7.03 1.59
68 INT267875 Phosphorylation of St13 6 0.12 1.69 1.55
69 INT139546 Gene_expression of URI1 3 0.75 3 1.49
70 INT144620 Gene_expression of Hsp90ab1 1 0.75 0.87 1.47
71 INT144621 Positive_regulation of Hsp90ab1 1 0.67 0.92 1.47
72 INT308527 Regulation of Gene_expression of HSP90B1 2 0.26 5.31 1.46
73 INT118559 Positive_regulation of Hspa5 20 0.61 15.66 1.45
74 INT125320 Negative_regulation of HSP90AA1 20 0.45 23.93 1.42
75 INT117122 Positive_regulation of Gene_expression of Hspa8 1 0.40 0.45 1.4
76 INT215366 Gene_expression of HSPE1 12 0.74 6.39 1.39
77 INT121480 Positive_regulation of St13 10 0.50 4.51 1.39
78 INT73180 Positive_regulation of Hspa8 7 0.37 3.41 1.37
79 INT81922 Regulation of Gene_expression of HSP90B2P 5 0.44 4.25 1.34
80 INT88855 Negative_regulation of Hsp90aa1 4 0.54 2.16 1.34
81 INT79053 Regulation of Tcp1 2 0.00 1.54 1.34
82 INT287798 Localization of AIP 1 0.63 5.96 1.31
83 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3
84 INT121481 Localization of St13 4 0.54 1.7 1.3
85 INT84701 Binding of HSP90B2P 8 0.47 7.37 1.29
86 INT139886 Gene_expression of PTGES3 11 0.72 1.5 1.27
87 INT195977 Transcription of Hsp90b1 5 0.56 1.74 1.27
88 INT66118 Binding of Calr 4 0.46 1.46 1.26
89 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
90 INT81575 Gene_expression of SIL1 29 0.25 19.76 1.24
91 INT339003 Gene_expression of ST13 3 0.75 0.37 1.24
92 INT314186 Gene_expression of Npm1 1 0.01 1.78 1.22
93 INT148946 Negative_regulation of CCT6A 2 0.02 0 1.21
94 INT54897 Negative_regulation of HSPA9 3 0.41 5.08 1.19
95 INT287799 Positive_regulation of Gene_expression of AIP 1 0.42 7.39 1.19
96 INT221213 Negative_regulation of Hspa9 7 0.34 2.79 1.18
97 INT102880 Regulation of CCT6A 1 0.06 0.05 1.18
98 INT112891 Regulation of Gene_expression of HSPD1 2 0.43 3.98 1.17
99 INT164704 Positive_regulation of Calr 1 0.23 0.41 1.15
100 INT209299 Positive_regulation of Gene_expression of St13 8 0.36 1.72 1.13
101 INT247615 Binding of URI1 2 0.20 1.17 1.13
102 INT133898 Binding of HSP90AA1 17 0.30 8.83 1.12
103 INT314193 Positive_regulation of Trap1 1 0.11 1.19 1.11
104 INT132531 Positive_regulation of TAPBP 8 0.49 2.84 1.09
105 INT154689 Regulation of HSPA9 1 0.26 0 1.09
106 INT129590 Localization of St13 4 0.61 0.67 1.03
107 INT117622 Positive_regulation of HSP90B1 3 0.43 4.84 1.02
108 INT143764 Positive_regulation of Binding of St13 1 0.49 0 1.02
109 INT71314 Regulation of Ptges3 1 0.13 0.84 1.02
110 INT228050 Negative_regulation of Negative_regulation of Tbce 1 0.04 0.96 1.02
111 INT100612 Positive_regulation of Hsp90aa1 4 0.64 5.3 1.01
112 INT187188 Binding of PPIA 3 0.47 1.1 1.01
113 INT228038 Positive_regulation of Gene_expression of Tbce 3 0.07 2.02 1.01
114 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99
115 INT227513 Positive_regulation of Phosphorylation of Hspa9 1 0.18 1.53 0.99
116 INT37170 Binding of APCS 6 0.36 4.79 0.97
117 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97
118 INT164066 Negative_regulation of SIL1 3 0.21 2.75 0.96
119 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
120 INT215371 Positive_regulation of HSPE1 1 0.66 3.4 0.95
121 INT130876 Gene_expression of Cct4 3 0.65 1.55 0.93
122 INT117581 Positive_regulation of Gene_expression of Ptges3 1 0.39 0.93 0.93
123 INT117584 Regulation of Gene_expression of Ptges3 1 0.21 0.93 0.93
124 INT227521 Regulation of Gene_expression of Hspa9 2 0.36 2.25 0.92
125 INT215360 Binding of HSPE1 1 0.36 3.63 0.92
126 INT81925 Positive_regulation of Positive_regulation of HSPA1B 1 0.02 0.74 0.91
127 INT88861 Positive_regulation of Gene_expression of Hsp90aa1 4 0.64 7.43 0.9
128 INT227527 Phosphorylation of Hspa9 1 0.29 1.4 0.89
129 INT137857 Positive_regulation of SCG5 3 0.49 1.01 0.88
130 INT159015 Positive_regulation of Localization of HSPA5 1 0.36 0.33 0.88
131 INT159013 Localization of HSPA5 2 0.42 0.32 0.87
132 INT67808 Positive_regulation of Uggt1 2 0.64 0 0.86
133 INT99156 Binding of HSPA5 3 0.38 0.57 0.84
134 INT135412 Positive_regulation of Trap1 2 0.18 1.49 0.84
135 INT227520 Positive_regulation of Gene_expression of Hspa9 4 0.40 4.16 0.83
136 INT337008 Binding of HSP90B1 2 0.20 4.91 0.81
137 INT239370 Gene_expression of DNAJA1 29 0.65 32.09 0.74
138 INT17021 Negative_regulation of AHSP 5 0.43 3.45 0.72
139 INT184157 Gene_expression of Ptges3 6 0.45 2.93 0.71
140 INT215362 Positive_regulation of Gene_expression of HSPE1 1 0.44 1.82 0.71
141 INT303885 Negative_regulation of Serpinh1 5 0.05 1.68 0.7
142 INT132528 Gene_expression of TAPBP 17 0.65 5.93 0.69
143 INT73977 Gene_expression of Serpinh1 14 0.54 8.14 0.69
144 INT238293 Gene_expression of DNAJB6 7 0.25 2.01 0.69
145 INT256673 Positive_regulation of Hsp90b1 12 0.49 8.49 0.68
146 INT230087 Binding of TOR1A 6 0.35 2.84 0.68
147 INT278334 Negative_regulation of Hsp90ab1 3 0.30 4.34 0.68
148 INT342507 Regulation of HSP90B1 1 0.26 2.29 0.67
149 INT339006 Binding of ST13 1 0.04 0 0.67
150 INT227522 Regulation of Hspa9 4 0.39 1.85 0.66
151 INT17018 Positive_regulation of Localization of AHSP 3 0.70 0.6 0.66
152 INT52910 Localization of SIL1 2 0.19 1.03 0.66
153 INT296769 Negative_regulation of ST13 2 0.01 0.12 0.66
154 INT67807 Positive_regulation of Gene_expression of Uggt1 1 0.64 0 0.66
155 INT90203 Negative_regulation of Cct2 2 0.35 0.34 0.65
156 INT350004 Positive_regulation of Binding of Tbce 1 0.07 1.86 0.65
157 INT77914 Binding of LRPAP1 5 0.47 1.1 0.64
158 INT298031 Localization of Clgn 1 0.26 3.91 0.64
159 INT177557 Positive_regulation of Calr 12 0.48 5.47 0.61
160 INT244935 Binding of St13 6 0.35 4.77 0.61
161 INT184691 Positive_regulation of Dnajb6 1 0.01 5.04 0.61
162 INT162801 Localization of CALR 7 0.73 8.69 0.6
163 INT192235 Binding of Hsp90aa1 6 0.19 1.46 0.6
164 INT88859 Transcription of Hsp90aa1 1 0.58 1.51 0.6
165 INT166086 Binding of Hsp90aa1 1 0.28 0.08 0.6
166 INT165847 Positive_regulation of HSP90AB1 1 0.60 0.31 0.6
167 INT136813 Positive_regulation of Cct4 1 0.01 1.45 0.6
168 INT88857 Negative_regulation of Transcription of Hsp90aa1 1 0.36 1.52 0.6
169 INT39730 Gene_expression of PFDN4 4 0.75 2.4 0.59
170 INT102664 Regulation of DNAJC5 3 0.14 0.94 0.59
171 INT227116 Regulation of Dnajc10 2 0.43 0.53 0.59
172 INT165846 Regulation of HSP90AA1 4 0.27 2.19 0.58
173 INT159968 Positive_regulation of Tbca 2 0.04 0.61 0.58
174 INT28931 Negative_regulation of LRPAP1 6 0.57 1.42 0.57
175 INT95879 Regulation of Gene_expression of St13 2 0.33 1.02 0.57
176 INT37169 Positive_regulation of Binding of APCS 2 0.45 2.4 0.57
177 INT136812 Negative_regulation of Cct4 1 0.01 1.44 0.57
178 INT136814 Negative_regulation of Gene_expression of Cct4 1 0.01 1.44 0.57
179 INT117583 Positive_regulation of Ptges3 1 0.36 0.59 0.57
180 INT127480 Negative_regulation of Hsp90aa1 20 0.57 10.67 0.56
181 INT128056 Gene_expression of CHAF1A 1 0.58 0 0.56
182 INT165849 Protein_catabolism of HSP90AB1 1 0.56 0.28 0.56
183 INT128055 Positive_regulation of CHAF1A 1 0.45 0 0.56
184 INT256690 Binding of Hsp90b1 11 0.30 5.94 0.55
185 INT154613 Regulation of Aip 5 0.21 3.86 0.55
186 INT130711 Positive_regulation of DNAJB11 2 0.16 0.79 0.55
187 INT144622 Regulation of Gene_expression of Hsp90ab1 1 0.60 0.31 0.55
188 INT130710 Positive_regulation of DNAJB9 1 0.44 0.79 0.55
189 INT232453 Negative_regulation of DNAJA3 1 0.41 0 0.54
190 INT277994 Binding of Trap1 7 0.26 6.21 0.53
191 INT177456 Positive_regulation of D630042P16Rik 1 0.01 1.22 0.53
192 INT130507 Negative_regulation of Ptges3 1 0.35 0.81 0.53
193 INT209310 Regulation of St13 3 0.16 0.17 0.52
194 INT154449 Positive_regulation of Gene_expression of Aip 2 0.43 2.88 0.52
195 INT56370 Gene_expression of HSPA2 1 0.03 0.13 0.52
196 INT271898 Binding of DNAJC7 1 0.16 0.36 0.52
197 INT164518 Gene_expression of PPIA 7 0.75 3.92 0.5
198 INT43576 Protein_catabolism of St13 1 0.11 0 0.5
199 INT17019 Positive_regulation of AHSP 3 0.70 1.85 0.49
200 INT172076 Binding of DNAJB6 1 0.35 1.08 0.49
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