INT100043

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Context Info
Confidence 0.08
First Reported 2001
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.08
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (COX18) mitochondrion (COX18)
Anatomy Link Frequency
PC-3 1
COX18 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 13 85.08 High High
COX-2 inhibitor 9 76.32 Quite High
Inflammation 46 75.00 Quite High
Inflammatory marker 2 37.68 Quite Low
Inflammatory response 3 25.80 Quite Low
COX2 1 25.00 Low Low
cytokine 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 5 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 4 97.56 Very High Very High Very High
INFLAMMATION 56 84.84 Quite High
Frailty 2 75.00 Quite High
Prostate Cancer 1 75.00 Quite High
Prostatic Intraepithelial Neoplasia 1 71.60 Quite High
Adhesions 7 68.04 Quite High
Stress 5 67.48 Quite High
Cancer 17 59.44 Quite High
Necrosis 1 48.44 Quite Low
Inflammatory Bowel Disease 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was no detectable change in the level of COX-1 protein after VEGF stimulation (fig 1B).
Neg (no) Regulation (change) of COX-1 protein
1) Confidence 0.08 Published 2008 Journal Gut Section Body Doc Link PMC2582343 Disease Relevance 0.20 Pain Relevance 0
In the cell lines, LNCaP, DU145, PC-3, and TSU, COX-2 protein expression was undetectable under basal conditions but could be induced transiently by phorbol ester treatment in PC-3 and TSU cells, but not in DU145 and LNCaP cells.
Regulation (undetectable) of COX-2 protein in PC-3
2) Confidence 0.04 Published 2001 Journal Cancer Res. Section Abstract Doc Link 11751373 Disease Relevance 0.80 Pain Relevance 0.15
treatment induced the expression of COX-2 and iNOS proteins without affecting the level of COX-1 protein (Fig. 6A).
Neg (without) Regulation (affecting) of COX-1 protein
3) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2879362 Disease Relevance 0.08 Pain Relevance 0.20

General Comments

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