INT100045

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Context Info
Confidence 0.09
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.80
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (COX18) mitochondrion (COX18)
Anatomy Link Frequency
PC-3 2
COX18 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 4 85.08 High High
Inflammation 3 75.00 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 4 97.56 Very High Very High Very High
INFLAMMATION 6 84.84 Quite High
Frailty 2 75.00 Quite High
Prostate Cancer 1 75.00 Quite High
Prostatic Intraepithelial Neoplasia 1 71.60 Quite High
Cancer 1 59.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the cell lines, LNCaP, DU145, PC-3, and TSU, COX-2 protein expression was undetectable under basal conditions but could be induced transiently by phorbol ester treatment in PC-3 and TSU cells, but not in DU145 and LNCaP cells.
Regulation (undetectable) of Gene_expression (expression) of COX-2 protein in PC-3
1) Confidence 0.09 Published 2001 Journal Cancer Res. Section Abstract Doc Link 11751373 Disease Relevance 0.80 Pain Relevance 0.15
RESULTS: Drug administration did not significantly affect endoscopic mucosal scores, histologic scores, or COX-1 or -2 protein expression.
Neg (not) Regulation (affect) of Gene_expression (expression) of COX-1 or -2 protein
2) Confidence 0.01 Published 2009 Journal Am. J. Vet. Res. Section Body Doc Link 19795939 Disease Relevance 0 Pain Relevance 0

General Comments

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