INT100057

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Context Info
Confidence 0.50
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.08
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MUC4) cell adhesion (MUC4) proteinaceous extracellular matrix (MUC4)
plasma membrane (MUC4) biological_process (MUC4)
MUC4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 7 99.72 Very High Very High Very High
metalloproteinase 4 31.76 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 69 99.76 Very High Very High Very High
Pancreatitis 7 99.72 Very High Very High Very High
Adenocarcinoma 23 99.22 Very High Very High Very High
Adhesions 7 94.64 High High
Solid Tumor 1 91.88 High High
Pancreatic Cancer 31 87.20 High High
Disease 4 71.92 Quite High
Disease Progression 1 68.76 Quite High
Metastasis 18 61.04 Quite High
Apoptosis 6 57.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance.
Positive_regulation (role) of MUC4 associated with adenocarcinoma, cancer and chronic pancreatitis
1) Confidence 0.50 Published 2001 Journal Clin. Cancer Res. Section Title Doc Link 11751498 Disease Relevance 0.30 Pain Relevance 0.19
CONCLUSIONS: Overall, this work demonstrates that pancreatic mucin MUC4 is a tumor-associated mucin.
Positive_regulation (tumor-associated) of MUC4
2) Confidence 0.50 Published 2001 Journal Clin. Cancer Res. Section Body Doc Link 11751498 Disease Relevance 0.23 Pain Relevance 0
CONCLUSIONS: Overall, this work demonstrates that pancreatic mucin MUC4 is a tumor-associated mucin.
Positive_regulation (pancreatic) of MUC4
3) Confidence 0.50 Published 2001 Journal Clin. Cancer Res. Section Body Doc Link 11751498 Disease Relevance 0.24 Pain Relevance 0
Therefore, the elevated CEACAM 1, -5 and -6 and MUC4 levels in PaCa 5061 cells may well contribute to the high metastatic potential of these cells as well.
Positive_regulation (elevated) of MUC4
4) Confidence 0.29 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2927995 Disease Relevance 1.31 Pain Relevance 0.05

General Comments

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