INT100064

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Context Info
Confidence 0.45
First Reported 2002
Last Reported 2010
Negated 7
Speculated 1
Reported most in Body
Documents 17
Total Number 20
Disease Relevance 6.06
Pain Relevance 1.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (DBP)
Anatomy Link Frequency
blood 2
liver 1
CSF 1
EPI 1
heart 1
DBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 177 98.76 Very High Very High Very High
Analgesic 5 95.68 Very High Very High Very High
headache 11 92.88 High High
Pain score 4 87.00 High High
Inflammatory response 3 86.44 High High
analgesia 3 86.32 High High
intrathecal 3 79.92 Quite High
cytokine 3 70.52 Quite High
lidocaine 6 61.36 Quite High
Sciatic nerve 1 57.20 Quite High
Disease Link Frequency Relevance Heat
Stress 85 99.32 Very High Very High Very High
Demyelinating Disease 180 98.76 Very High Very High Very High
Weight Loss 23 93.52 High High
Headache 11 92.88 High High
Blister 1 91.16 High High
Paralysis 3 90.76 High High
Body Weight 23 89.04 High High
Hypoxia 4 88.24 High High
INFLAMMATION 25 86.08 High High
Hypertension 64 85.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Edrophonium had no effect on SBP and DBP.
Neg (no) Regulation (effect) of DBP
1) Confidence 0.45 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11752105 Disease Relevance 0 Pain Relevance 0
The supplement had no statistically significant effect on blood EPI or NE concentration, or on HR, SBP, or DBP.
Neg (no) Regulation (effect) of DBP in EPI
2) Confidence 0.38 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2912905 Disease Relevance 0.22 Pain Relevance 0
Correlation between change in vascular leakage and change in diastolic blood pressure or fluid variables As expected from the vascular hypothesis, changes in DBP in patients receiving rosiglitazone were strongly inversely correlated to changes in vascular leakage in participants with high Ewing scores (r?
Regulation (changes) of DBP in blood
3) Confidence 0.27 Published 2010 Journal Diabetologia Section Body Doc Link PMC2910895 Disease Relevance 0.17 Pain Relevance 0
Regarding heart rates, SpO2, SBP and DBP values, no significant differences were found between the groups.
Neg (no) Regulation (values) of DBP in heart
4) Confidence 0.26 Published 2005 Journal Int. J. Clin. Pract. Section Abstract Doc Link 15963202 Disease Relevance 0.07 Pain Relevance 0.74
Allosteric modulation of the TCA binding site may occur in the setting of phenytoin use.
Regulation (modulation) of binding site
5) Confidence 0.24 Published 2010 Journal Clin Toxicol (Phila) Section Body Doc Link 20507243 Disease Relevance 0 Pain Relevance 0
We measured GSN and DBP concentrations in blood and CSF obtained from patients diagnosed with MS (n = 56) in comparison to a control group (n = 20) that includes patients diagnosed with conditions such as idiopathic cephalgia (n = 11), idiopathic (Bell's) facial nerve palsy (n = 7) and ischialgia due to discopathy (n = 2).
Regulation (concentrations) of DBP in blood associated with multiple sclerosis, headache and paralysis
6) Confidence 0.20 Published 2010 Journal BMC Neurol Section Abstract Doc Link PMC2989318 Disease Relevance 0.71 Pain Relevance 0.36
At the same time, higher demand for vitamin D binding protein will be filled more effectively by increased liver production of this acute phase reactant, which would explain the lack of significant changes in the DBP blood concentration.
Regulation (changes) of DBP in liver
7) Confidence 0.20 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2989318 Disease Relevance 0.51 Pain Relevance 0.30
MAIN RESULTS: All postintubation values of SBP, DBP, MAP, and HR were significantly lower in the lidocaine group than the control group (P < 0.01).
Regulation (values) of DBP
8) Confidence 0.20 Published 2009 Journal J Clin Anesth Section Body Doc Link 19329013 Disease Relevance 0 Pain Relevance 0
RESULTS: General Linear Model procedures tested Emotion-Induction x Emotion SuppressionxAnger-Out or Anger-In (continuous)xPeriod (baseline, cold pressor, recovery) effects on pain intensity, SBP, DBP, and HR.
Regulation (effects) of DBP
9) Confidence 0.12 Published 2007 Journal Ann Behav Med Section Body Doc Link 17927554 Disease Relevance 0.05 Pain Relevance 0
No differences were observed between the novelty stress and stress periods on day 1 and between the control 1 and 2 on day 2 for SBP, DBP, MAP and HR.
Regulation (control) of DBP associated with stress
10) Confidence 0.12 Published 2005 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1185546 Disease Relevance 1.60 Pain Relevance 0
In Raff and colleagues’ (2006) investigation, a diet rich in CLAs didn’t alter SBP, DBP and pulse pressure, but this may be due to the short time for the study (five weeks).
Regulation (alter) of DBP
11) Confidence 0.10 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2663461 Disease Relevance 0.57 Pain Relevance 0
Changes in SBP, DBP, and HR caused by sevoflurane suggest that hemodynamic alterations may underlie its effects on IOP.


Regulation (Changes) of DBP
12) Confidence 0.08 Published 2007 Journal Am. J. Ophthalmol. Section Body Doc Link 17317393 Disease Relevance 0 Pain Relevance 0
We analyzed the alteration of SBP, DBP, SpO2, sedation level, the degree of pharyngeal malaise, recovery time, dose of propofol,the lethe degree of upset, and procedure of gastroscopy to evaluate the safety and the efficacy of the two methods in the analgesia gastroscopy for hypoxia predisposed patients.
Spec (analyzed) Regulation (alteration) of DBP
13) Confidence 0.08 Published 2005 Journal Zhong Nan Da Xue Xue Bao Yi Xue Ban Section Body Doc Link 16045027 Disease Relevance 0.09 Pain Relevance 0
These data suggest that the consumption of both F and JF have no affect on resting HR and DBP for 3-hours following ingestion.


Neg (no) Regulation (affect) of DBP
14) Confidence 0.08 Published 2007 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2098780 Disease Relevance 0.05 Pain Relevance 0
The significant difference in REE between the two trials occurred with a slight difference in SBP, while resting HR and DBP were not affected by the addition of 200 mg of caffeine over regular, caffeinated coffee, as well as the additional herbal ingredients that are present in the experimental coffee (JF).
Neg (not) Regulation (affected) of DBP
15) Confidence 0.08 Published 2007 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2098780 Disease Relevance 0.32 Pain Relevance 0.06
Resting HR and DBP were not affected with ingestion of either of the two coffees and both coffees were well tolerated with no significant reported side effects following ingestion.
Neg (not) Regulation (affected) of DBP
16) Confidence 0.08 Published 2007 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2098780 Disease Relevance 0.47 Pain Relevance 0
We measured GSN and DBP concentrations in blood and CSF obtained from patients diagnosed with MS (n = 56) in comparison to a control group (n = 20) that includes patients diagnosed with conditions such as idiopathic cephalgia (n = 11), idiopathic (Bell's) facial nerve palsy (n = 7) and ischialgia due to discopathy (n = 2).
Regulation (concentrations) of DBP in CSF associated with multiple sclerosis, headache and paralysis
17) Confidence 0.07 Published 2010 Journal BMC Neurol Section Abstract Doc Link PMC2989318 Disease Relevance 0.71 Pain Relevance 0.36
Caffeine supplementation at 6 mg/kg had no statistically significant effect on muscular endurance, HR, or DBP.
Neg (no) Regulation (effect) of DBP
18) Confidence 0.06 Published 2010 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2876999 Disease Relevance 0 Pain Relevance 0
In the present review, the RCTs of Jin et al., Deng et al., and Kim et al. [21,23,24] administered direct moxibustion therapy, and only the Deng et al. trial [23] employed suppurative moxibustion and showed significant efficacy in both the SBP and DBP at 30 min and 50 days after the moxibustion therapy.
Regulation (efficacy) of DBP
19) Confidence 0.04 Published 2010 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2912786 Disease Relevance 0.51 Pain Relevance 0.04
While the lethe degree of gastroscopy upset and alteration of SBP, DBP were rated similarly in both groups (P > 0.05), and the lethe degree of gastroscopy procedure in two-stage administration method group was significantly lower than that of routine continuum adminis- tration method group (P <0.01).
Regulation (alteration) of DBP
20) Confidence 0.04 Published 2005 Journal Zhong Nan Da Xue Xue Bao Yi Xue Ban Section Body Doc Link 16045027 Disease Relevance 0 Pain Relevance 0

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