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Context Info
Confidence 0.54
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 1.91
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (Hspd1) cytosol (Hspd1) mitochondrion (Hspd1)
extracellular space (Hspd1) Golgi apparatus (Hspd1) cytoplasm (Hspd1)
Anatomy Link Frequency
muscles 1
Hspd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 7 92.96 High High
addiction 2 50.00 Quite Low
agonist 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunization 4 97.60 Very High Very High Very High
Shock 152 96.24 Very High Very High Very High
Apoptosis 4 91.36 High High
Stress 23 89.92 High High
Toxicity 4 75.00 Quite High
Hepatotoxicity 2 74.92 Quite High
Fatigue 1 69.20 Quite High
Alzheimer's Dementia 1 63.84 Quite High
Necrosis 1 63.60 Quite High
Overdose 1 60.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These genes included a number of chaperones Hsp90aa1, Hspe1, Hspa4l, Hspd1 and Hsph1.
Negative_regulation (number) of Hspd1
1) Confidence 0.54 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823686 Disease Relevance 1.23 Pain Relevance 0
Chaperone proteins Hsp10 and Hsp60 were readily decreased by half in mitochondria at both doses, most likely by leaking into cytoplasm.
Negative_regulation (decreased) of Hsp60
2) Confidence 0.39 Published 2002 Journal Toxicol. Sci. Section Abstract Doc Link 11752693 Disease Relevance 0.58 Pain Relevance 0.42
Quantitative real-time PCR study on persistence of pDNA vaccine pVax-Hsp60 TM814 in beef muscles


Negative_regulation (persistence) of pVax-Hsp60 TM814 in muscles
3) Confidence 0.01 Published 2008 Journal Genet Vaccines Ther Section Title Doc Link PMC2542361 Disease Relevance 0.10 Pain Relevance 0

General Comments

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