INT100185

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Context Info
Confidence 0.25
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.83
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (LMNB1) nuclear envelope (LMNB1) structural molecule activity (LMNB1)
nucleus (LMNB1)
Anatomy Link Frequency
muscle 1
UMNs 1
blood cells 1
LMNB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 12 93.68 High High
antagonist 4 81.36 Quite High
GABA receptor 1 78.88 Quite High
agonist 1 77.76 Quite High
Angina 2 76.64 Quite High
Inflammation 11 62.12 Quite High
tetrodotoxin 1 61.12 Quite High
Hippocampus 9 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Motor Neuron Diseases 107 99.52 Very High Very High Very High
Myocardial Infarction 57 83.72 Quite High
Cv Unclassified Under Development 35 83.36 Quite High
Disease 36 79.48 Quite High
Angina 2 76.64 Quite High
Apoptosis 5 62.72 Quite High
INFLAMMATION 20 62.12 Quite High
Congenital Anomalies 3 60.48 Quite High
Parkinson's Disease 6 58.52 Quite High
Stress 24 56.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
0.01, Pearson correlation) and we observed more LMNB1 mRNA in blood cells from VD+ than in those from VD?
Positive_regulation (more) of LMNB1 in blood cells
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2836383 Disease Relevance 0.68 Pain Relevance 0.08
The corticospinal tract volume is reduced [8] and UMNs are depleted [9,10] in ALS patients, and UMNs are required for LMN function and muscle control [11].
Positive_regulation (required) of LMN in UMNs associated with motor neuron diseases
2) Confidence 0.07 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1796866 Disease Relevance 1.15 Pain Relevance 0.15
Conversely, chronic in ovo administration of d-tubocurarine, which causes an increase in motoneuron branching on the surface of the muscle target tissue, evoked a 1.8-fold increase in average LMN K(Ca) density measured at E11.
Positive_regulation (increase) of LMN in muscle
3) Confidence 0.03 Published 2002 Journal J. Neurosci. Section Abstract Doc Link 11756490 Disease Relevance 0 Pain Relevance 0.18

General Comments

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