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Context Info
Confidence 0.48
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.70
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

SPANXB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
B1 receptor 8 100.00 Very High Very High Very High
bradykinin 2 100.00 Very High Very High Very High
Pain 4 93.88 High High
Inflammation 5 93.20 High High
Taxol 2 83.16 Quite High
alcohol 18 80.60 Quite High
Lasting pain 1 61.48 Quite High
Kinase C 1 61.12 Quite High
antagonist 2 57.84 Quite High
Action potential 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thiamine Deficiency 1 99.36 Very High Very High Very High
Breast Cancer 68 97.68 Very High Very High Very High
Apoptosis 48 97.00 Very High Very High Very High
Eating Disorder 1 96.08 Very High Very High Very High
Lactic Acidosis 1 95.84 Very High Very High Very High
Heart Rate Under Development 2 94.88 High High
Pain 3 93.88 High High
INFLAMMATION 5 93.20 High High
Hepatocellular Cancer 2 91.56 High High
Fibrosarcoma 3 90.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Precautions had to be taken to prevent B1 peptide loss to container surfaces and contamination of the HPLC-MS/MS.
Negative_regulation (loss) of B1 associated with b1 receptor
1) Confidence 0.48 Published 2010 Journal J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. Section Abstract Doc Link 20167545 Disease Relevance 0.06 Pain Relevance 0.36
Bariatric surgery patients represent another group at risk of micronutrient deficiency, including B1 deficiency [8,9].
Negative_regulation (deficiency) of B1
2) Confidence 0.13 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC3016303 Disease Relevance 1.43 Pain Relevance 0.11
This was associated with downregulation of the levels of cyclins D1 and B1, and with inhibition of CDK1, CDK2 and CDK4.
Negative_regulation (downregulation) of B1
3) Confidence 0.13 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2575526 Disease Relevance 0.63 Pain Relevance 0.07
Their effects are mediated by at least two types of bradykinin receptors--B1 and B2.
Negative_regulation (types) of B1 associated with b1 receptor and bradykinin
4) Confidence 0.10 Published 2001 Journal Ginekol. Pol. Section Abstract Doc Link 11757483 Disease Relevance 0.19 Pain Relevance 0.28
This is similar to the effect of A1, B1 (not shown) and C1 extract observed herein.
Negative_regulation (effect) of B1
5) Confidence 0.03 Published 2006 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1513146 Disease Relevance 0.40 Pain Relevance 0

General Comments

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