INT10026

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Context Info
Confidence 0.05
First Reported 1987
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.27
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
blood 1
vesicle 1
Gtpc (Mus musculus)
Pain Link Frequency Relevance Heat
halothane 15 100.00 Very High Very High Very High
Glutamate 1 99.76 Very High Very High Very High
nMDA receptor 4 98.46 Very High Very High Very High
anesthesia 4 96.96 Very High Very High Very High
Disease Link Frequency Relevance Heat
Heart Rate Under Development 2 99.56 Very High Very High Very High
Sleep Disorders 1 95.28 Very High Very High Very High
Stroke 1 77.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NMDA receptor-mediated responses were determined by measurement of L-glutamate-stimulated increases in free intracellular calcium concentration (Cai) using the fluorescent indicator for Cai, Indo 1, in microsacs (a cell-free brain membrane vesicle preparation) isolated from hippocampi or cerebral cortices of the two mouse lines.
Positive_regulation (increases) of concentration in vesicle associated with glutamate and nmda receptor
1) Confidence 0.05 Published 1994 Journal Alcohol. Clin. Exp. Res. Section Abstract Doc Link 7695048 Disease Relevance 0 Pain Relevance 0.27
Heart rate increased significantly as the concentration of halothane was increased, but arterial blood pressure did not change.
Positive_regulation (increased) of concentration in blood associated with heart rate under development and halothane
2) Confidence 0.01 Published 1992 Journal Vet Surg Section Abstract Doc Link 1455642 Disease Relevance 0.19 Pain Relevance 0.30
One hour after anesthetic induction, end-tidal concentration was set at 1.04% HAL or 0.28% MOF [each representing 1.2 minimum alveolar concentration (MAC) for dogs] and maintained for 7 h.
Positive_regulation (induction) of concentration associated with halothane
3) Confidence 0.00 Published 1987 Journal J. Appl. Physiol. Section Abstract Doc Link 3693168 Disease Relevance 0.08 Pain Relevance 0.43

General Comments

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