INT100275

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Context Info
Confidence 0.25
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 19
Total Number 24
Disease Relevance 6.99
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TBL1XR1) small molecule metabolic process (TBL1XR1) histone binding (TBL1XR1)
nucleolus (TBL1XR1) nucleus (TBL1XR1) DNA binding (TBL1XR1)
Anatomy Link Frequency
Skin 3
bulb 2
chondrocytes 1
band 1
PGE2 1
TBL1XR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 6 99.96 Very High Very High Very High
Perioperative pain 10 85.00 Quite High
Pain 588 81.12 Quite High
Analgesic 78 78.64 Quite High
nociceptor 10 75.12 Quite High
psoriasis 6 64.04 Quite High
imagery 62 54.08 Quite High
antagonist 4 50.00 Quite Low
Inflammation 116 39.68 Quite Low
visual analogue scale 70 10.60 Low Low
Disease Link Frequency Relevance Heat
Sleep Disorders 6 99.96 Very High Very High Very High
Contusions 6 99.68 Very High Very High Very High
Wound Healing 538 99.52 Very High Very High Very High
Injury 784 98.88 Very High Very High Very High
Venous Stasis Ulcers 236 97.68 Very High Very High Very High
Disease 6 95.60 Very High Very High Very High
Low Back Pain 8 95.20 Very High Very High Very High
Ulcers 1080 89.60 High High
Infection 98 88.12 High High
Wound Infection 48 85.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Technically water-filtered infrared-A (wIRA) is produced in special radiators, whose whole incoherent broad-band radiation of a 3000 Kelvin halogen bulb is passed through a cuvette, containing water, which absorbs or decreases the described undesired wavelengths within infrared [1], [2], [4], see Figure 2 (Fig. 2): an example of the resulting spectrum with visible light (VIS) and water-filtered infrared-A (wIRA) is shown in Figure 3 (Fig. 3).
Gene_expression (produced) of wIRA in band
1) Confidence 0.25 Published 2007 Journal GMS Krankenhaushygiene Interdisziplinar Section Body Doc Link PMC2831244 Disease Relevance 0.06 Pain Relevance 0
Working mechanisms of wIRA
Gene_expression (mechanisms) of wIRA
2) Confidence 0.25 Published 2007 Journal GMS Krankenhaushygiene Interdisziplinar Section Body Doc Link PMC2831244 Disease Relevance 0.07 Pain Relevance 0
Bechterew [77], arthroses, arthritises, contusions; fibromyalgia (preferably wIRA in combination with motion, i.e. wIRA with a small amount of ergometer work) [93], regeneration after sports [78] (wIRA alone or wIRA in combination with motion), postoperative rehabilitation [89], [94], improvement of lipolysis (wIRA in combination with motion) [61].
Gene_expression (preferably) of wIRA associated with contusions and fibrositis
3) Confidence 0.22 Published 2007 Journal GMS Krankenhaushygiene Interdisziplinar Section Body Doc Link PMC2831244 Disease Relevance 1.19 Pain Relevance 0.08
Why wIRA?
Gene_expression (Why) of wIRA
4) Confidence 0.22 Published 2007 Journal GMS Krankenhaushygiene Interdisziplinar Section Body Doc Link PMC2831244 Disease Relevance 0.10 Pain Relevance 0
Water-filtered infrared-A as a special form of heat radiation with a high tissue penetration and with a low thermal load to the skin surface acts both by thermal (related to heat energy transfer) and thermic (temperature depending, with a relevant change of temperature) as well as by non-thermal (without a relevant transfer of heat energy) and non-thermic (not depending on temperature, without a relevant change of temperature) effects. wIRA produces a therapeutically usable field of heat in the tissue and increases tissue temperature, tissue oxygen partial pressure, and tissue perfusion.
Gene_expression (produces) of wIRA in skin
5) Confidence 0.22 Published 2007 Journal GMS Krankenhaushygiene Interdisziplinar Section Abstract Doc Link PMC2831244 Disease Relevance 0.36 Pain Relevance 0
Technically water-filtered infrared-A (wIRA) is produced in special radiators, whose full spectrum of radiation of a halogen bulb is passed through a cuvette, containing water, which absorbs or decreases the described undesired wavelengths of the infrared radiation.
Gene_expression (produced) of wIRA in bulb
6) Confidence 0.19 Published 2007 Journal GMS Krankenhaushygiene Interdisziplinar Section Abstract Doc Link PMC2831244 Disease Relevance 0.08 Pain Relevance 0
A typical image of the stratum corneum after application of the fluorescein sodium containing formulation, without wIRA irradiation, is presented in Figure 6a (Fig. 6).
Gene_expression (irradiation) of wIRA
7) Confidence 0.17 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703260 Disease Relevance 0 Pain Relevance 0
Skin hydration (in relative (arbitrary) units) rose from 67 before wIRA to 87 after wIRA irradiation (medians) (Figure 9 (Fig. 9)).
Gene_expression (irradiation) of wIRA in Skin
8) Confidence 0.17 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703260 Disease Relevance 0 Pain Relevance 0
Thermal effects of wIRA and production of a therapeutically usable field of heat
Gene_expression (production) of wIRA
9) Confidence 0.06 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.41 Pain Relevance 0
Technically water-filtered infrared-A (wIRA) is produced in special radiators, in which the complete incoherent radiation of a 3000-Kelvin halogen bulb passes a water containing cuvette, so that the undesired portions of radiation are absorbed or decreased [17], [18], [19], [20].
Gene_expression (produced) of wIRA in bulb
10) Confidence 0.06 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.18 Pain Relevance 0
Clinical use and advantages of wIRA
Gene_expression (advantages) of wIRA
11) Confidence 0.06 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.66 Pain Relevance 0.05
Working mechanisms of wIRA
Gene_expression (mechanisms) of wIRA
12) Confidence 0.06 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.64 Pain Relevance 0.16
To assess the irradiation characteristics of the wIRA radiators, emitting wIRA(+VIS), a porous rubber mat was heated at a distance of 25 cm for a period of 10 minutes.
Gene_expression (radiators) of wIRA
13) Confidence 0.05 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.41 Pain Relevance 0
How can the beneficial effects of wIRA be explained?
Gene_expression (effects) of wIRA
14) Confidence 0.05 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.66 Pain Relevance 0.17
Skin heating patterns during treatment with a wIRA radiator
Gene_expression (radiator) of wIRA in Skin
15) Confidence 0.05 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.15 Pain Relevance 0
Previous clinical studies with wIRA concerning wound healing
Gene_expression (studies) of wIRA associated with wound healing
16) Confidence 0.05 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 1.30 Pain Relevance 0.86
To assess the irradiation characteristics of the wIRA radiators, emitting wIRA(+VIS), a porous rubber mat was heated at a distance of 25 cm for a period of 10 minutes.
Gene_expression (radiators) of wIRA
17) Confidence 0.05 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.41 Pain Relevance 0
Non-thermal effects of wIRA
Gene_expression (effects) of wIRA
18) Confidence 0.05 Published 2008 Journal GMS German Medical Science Section Body Doc Link PMC2703263 Disease Relevance 0.06 Pain Relevance 0
Aceclofenac may modulate PGE2 production by increasing IL-IRa production and decreasing NO synthesis.
Gene_expression (production) of IL-IRa in PGE2
19) Confidence 0.04 Published 2001 Journal J. Rheumatol. Section Body Doc Link 11764219 Disease Relevance 0 Pain Relevance 0
CONCLUSION: Proinflammatory stimuli induce IL-IRa synthesis in human articular chondrocytes.
Gene_expression (synthesis) of IL-IRa in chondrocytes
20) Confidence 0.04 Published 2001 Journal J. Rheumatol. Section Body Doc Link 11764219 Disease Relevance 0 Pain Relevance 0

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