INT100284

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Context Info
Confidence 0.65
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (TXN, POMC) cell-cell signaling (TXN, POMC) cytoplasm (TXN, POMC)
signal transduction (TXN, POMC) extracellular region (TXN, POMC) nucleoplasm (TXN)
Anatomy Link Frequency
melanocytes 2
TXN (Homo sapiens)
POMC (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 98.60 Very High Very High Very High
melanocortin 1 receptor 2 75.00 Quite High
Neuropeptide 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Death 1 46.16 Quite Low
Shock 1 37.12 Quite Low
Stress 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously reported that TRX released from UVB-irradiated keratinocytes stimulates melanogenesis by upregulating MSH receptor expression and its binding activity in melanocytes.
TRX Positive_regulation (upregulating) of Gene_expression (expression) of MSH in melanocytes
1) Confidence 0.65 Published 2001 Journal J. Investig. Dermatol. Symp. Proc. Section Abstract Doc Link 11764282 Disease Relevance 0 Pain Relevance 0.19

General Comments

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