INT100324

Context Info Confidence 0.27 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.19 Pain Relevance 0.38

aging (AQP2) plasma membrane (AQP2) protein complex (AQP2) transmembrane transport (AQP2) lysosome (AQP2) cytoplasm (AQP2)

Anatomy Link Frequency plasma 2 AQP2 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 4 98.64

Disease Link Frequency Relevance Heat INFLAMMATION 2 98.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Effect of an acute oral ibuprofen intake on urinary aquaporin-2 excretion in healthy humans.

Regulation (Effect) of Localization (excretion) of aquaporin-2

1) Confidence 0.27 Published 2001 Journal Scand. J. Clin. Lab. Invest. Section Title Doc Link 11768323 Disease Relevance 0.10 Pain Relevance 0.20

The purpose was to measure the effect of ibuprofen on urinary excretion of aquaporin-2 (u-AQP2), urinary output, urinary osmolality (u-osm) and plasma concentration of vasopressin (AVP) in a dose-response study using placebo and ibuprofen 600mg and 1200mg.

Regulation (effect) of Localization (excretion) of AQP2 in plasma

2) Confidence 0.27 Published 2001 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 11768323 Disease Relevance 0.09 Pain Relevance 0.18

General Comments

This test has worked.