INT100326

Context Info Confidence 0.69 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

aging (AQP2) plasma membrane (AQP2) protein complex (AQP2) transmembrane transport (AQP2) lysosome (AQP2) cytoplasm (AQP2)

Anatomy Link Frequency urine 2 AQP2 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 2 40.68

Disease Link Frequency Relevance Heat INFLAMMATION 1 40.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We suggest that the increased excretion of AQP2 can be explained by an increase in the ratio of AQP2 that is shed into the urine because the endocytic retrieval of AQP2 from the apical membrane is impaired.

Positive_regulation (increased) of Localization (excretion) of AQP2 in urine

1) Confidence 0.69 Published 2001 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 11768323 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.