INT100369

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Context Info
Confidence 0.29
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HIF1A, VEGFA) cell differentiation (HIF1A) signal transducer activity (HIF1A)
extracellular space (VEGFA) signal transduction (HIF1A) growth (VEGFA)
HIF1A (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 8 98.36 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hypoxia 7 100.00 Very High Very High Very High
Cancer 3 89.44 High High
Ulcers 1 73.12 Quite High
INFLAMMATION 1 69.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because HIF-1alpha is the major trigger for hypoxia-induced activation of the VEGF and Flt-1 genes, this could explain how NSAIDs inhibit hypoxia-induced angiogenesis.
HIF-1alpha Positive_regulation (trigger) of Positive_regulation (activation) of VEGF associated with hypoxia and cinod
1) Confidence 0.29 Published 2002 Journal FASEB J. Section Abstract Doc Link 11772947 Disease Relevance 0.99 Pain Relevance 0.62

General Comments

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