INT100383

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Context Info
Confidence 0.01
First Reported 2002
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.20
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (FRA10AC1)
FRA10AC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 4 96.08 Very High Very High Very High
sodium channel 3 75.00 Quite High
local anesthetic 1 43.76 Quite Low
Pain 1 40.48 Quite Low
Disease Link Frequency Relevance Heat
Syndrome 5 100.00 Very High Very High Very High
Intellectual Impairment 2 96.28 Very High Very High Very High
Spermatic Cord Torsion 5 96.08 Very High Very High Very High
Emergencies 1 92.00 High High
Fragile X Syndrome 1 75.00 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although macroorchidism has been recognized as a cardinal feature of FraX, descriptions of testicular pathology are rare.
FraX Binding (recognized) of associated with syndrome
1) Confidence 0.01 Published 2002 Journal Pediatrics Section Abstract Doc Link 11773584 Disease Relevance 1.20 Pain Relevance 0
The data suggest that use-dependent binding at the F1760 site results in enhanced slow inactivation rather than alteration of drug association and dissociation from that site and may be a general mechanism of action of sodium-channel blocking agents.
F1760 site Binding (binding) of
2) Confidence 0.00 Published 2005 Journal J. Membr. Biol. Section Abstract Doc Link 16477531 Disease Relevance 0 Pain Relevance 0.42

General Comments

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