INT100514

Context Info Confidence 0.02 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.22

signal transduction (Oprl1) nucleus (Tbpl1) plasma membrane (Oprl1) DNA binding (Tbpl1) cytoplasm (Tbpl1) signal transducer activity (Oprl1)

Oprl1 (Mus musculus) Tbpl1 (Mus musculus)

Pain Link Frequency Relevance Heat opiate 2 100.00 Central nervous system 1 88.64 Limbic system 2 75.00 Nucleus accumbens 1 48.32

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Recently, endomorphin-1 (Tyr-Pro-Trp-Phe-NH2; EM1), an endogenous peptide that has high affinity and selectivity for the mu-opiate receptor, has been shown to modulate emotional behavior in mice and social behavior in Syrian hamsters.

mu-opiate receptor Binding (affinity) of Trp associated with opiate

1) Confidence 0.02 Published 2001 Journal Brain Res. Bull. Section Abstract Doc Link 11786242 Disease Relevance 0 Pain Relevance 0.22

General Comments

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