INT100593

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Context Info
Confidence 0.65
First Reported 2002
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 8
Total Number 9
Disease Relevance 13.81
Pain Relevance 5.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (UBAP1)
Anatomy Link Frequency
plaque 1
UBAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 85 100.00 Very High Very High Very High
Inflammation 6 91.20 High High
cytokine 3 86.24 High High
Inflammatory mediators 1 84.04 Quite High
metalloproteinase 14 79.32 Quite High
depression 3 73.84 Quite High
Inflammatory response 1 62.32 Quite High
Pain 4 5.00 Very Low Very Low Very Low
pain labor 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 74 100.00 Very High Very High Very High
Stable Angina Pectoris 11 100.00 Very High Very High Very High
Coronary Artery Disease 27 99.92 Very High Very High Very High
Myocardial Infarction 56 99.72 Very High Very High Very High
Hyperlipidemia 3 99.24 Very High Very High Very High
Diabetes Mellitus 3 98.86 Very High Very High Very High
Hypertension 3 98.48 Very High Very High Very High
Acute-phase Reaction 2 96.04 Very High Very High Very High
Nasopharynx Cancer 290 95.04 Very High Very High Very High
Disease 27 94.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, IL-10 concentrations were significantly lower in the SAP and UAP groups.
Gene_expression (lower) of UAP associated with angina
1) Confidence 0.65 Published 2003 Journal Am. J. Cardiol. Section Abstract Doc Link 12521622 Disease Relevance 1.40 Pain Relevance 1.43
The UAP's practice during the third stage of labor seems to be beneficial.
Gene_expression (practice) of UAP
2) Confidence 0.56 Published 2010 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC2940791 Disease Relevance 0.09 Pain Relevance 0
This was done so that variables denoting the presence or absence of UAP, IHD, HF or other cardiac conditions in any secondary diagnosis field could be added to patient records as a crude marker of disease severity.
Neg (absence) Gene_expression (absence) of UAP associated with angina, coronary artery disease, disease and myocardial infarction
3) Confidence 0.52 Published 2010 Journal Int J Equity Health Section Body Doc Link PMC2823593 Disease Relevance 1.68 Pain Relevance 0.23
Using bioinformatics to analyze the expression and location of UBAP1 protein, it was found that EGFP/UBAP1 was expressed and existed mainly in the nuclear, especially accumulated on the nuclear envelope.
Gene_expression (expressed) of UBAP1
4) Confidence 0.43 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1774581 Disease Relevance 1.58 Pain Relevance 0
Using bioinformatics to analyze the expression and location of UBAP1 protein, it was found that EGFP/UBAP1 was expressed and existed mainly in the nuclear, especially accumulated on the nuclear envelope.
Spec (analyze) Gene_expression (expression) of UBAP1
5) Confidence 0.43 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1774581 Disease Relevance 1.59 Pain Relevance 0
In multivariate analysis, MMP-8 level was an independent factor for UAP.
Gene_expression (level) of UAP associated with angina
6) Confidence 0.32 Published 2010 Journal Atherosclerosis Section Abstract Doc Link 19674746 Disease Relevance 1.54 Pain Relevance 1.12
Thus, plasma MMP-8 levels were found to be high in patients with UAP, suggesting that MMP-8 levels in UAP may reflect coronary plaque instability and that MMP-8 is a promising biomarker for UAP.
Gene_expression (levels) of UAP in plaque associated with angina
7) Confidence 0.32 Published 2010 Journal Atherosclerosis Section Abstract Doc Link 19674746 Disease Relevance 1.56 Pain Relevance 1.07
A study by Inoue et al.26) compared 52 patients with stable angina pectoris (SAP) to 16 patients with UAP and reported that PTX3 was not associated with coronary risk factors including hypertension, diabetes mellitus and hyperlipidemia; the value of PTX3 was significantly higher in the UAP than in the SAP group.
Gene_expression (higher) of UAP associated with stable angina pectoris, angina, diabetes mellitus, hypertension and hyperlipidemia
8) Confidence 0.06 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2933461 Disease Relevance 1.80 Pain Relevance 0.74
However, whereas CRP is strongly predictive of long-term D/AMI for patients presenting with SAP or UAP, it is not predictive shortly after AMI, suggesting that measurements should be delayed until the acute phase reaction is over and levels have returned to baseline.
Gene_expression (presenting) of UAP associated with angina, acute-phase reaction and myocardial infarction
9) Confidence 0.05 Published 2002 Journal Am. J. Cardiol. Section Abstract Doc Link 11792332 Disease Relevance 2.56 Pain Relevance 1.16

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