INT10060

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Context Info
Confidence 0.42
First Reported 1992
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 2.51
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (MB)
Anatomy Link Frequency
plasma 2
skeletal muscle tissue 1
thigh 1
MB (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 29 88.60 High High
dysesthesia 1 77.16 Quite High
Pain 14 71.76 Quite High
cytokine 4 59.56 Quite High
Angina 35 45.04 Quite Low
Inflammation 19 5.00 Very Low Very Low Very Low
cocaine 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Renal Failure 25 98.20 Very High Very High Very High
Rhabdomyolysis 101 97.72 Very High Very High Very High
Myalgia 11 95.52 Very High Very High Very High
Acute Coronary Syndrome 70 94.84 High High
Renal Failure 19 94.56 High High
Myocardial Infarction 46 91.84 High High
Hyperkalemia 6 91.24 High High
Hypercalcemia 1 88.96 High High
Coronary Artery Disease 26 88.60 High High
Pressure And Volume Under Development 3 88.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Twelve hours after admission, diagnostic performance was further improved for all CK and CK-MB methods but began to decline for myoglobin.
Negative_regulation (decline) of myoglobin
1) Confidence 0.42 Published 1992 Journal Clin. Chem. Section Abstract Doc Link 1458571 Disease Relevance 0.22 Pain Relevance 0.07
From starting Seiza, oxygenated hemoglobin/myoglobin decreased markedly and reached a plateau within about 6 min.
Negative_regulation (decreased) of myoglobin
2) Confidence 0.42 Published 2005 Journal J Hum Ergol (Tokyo) Section Abstract Doc Link 17393761 Disease Relevance 0.08 Pain Relevance 0.08
CONCLUSION: The data indicate that double layers of Farabloc fabric wrapped around the thigh reduces pain and strength loss and serum levels of malondialdehyde, creatine phosphokinase, myoglobin, leukocytes, and neutrophils when untrained human subjects are exposed to eccentric exercise to produce DOMS in the quadriceps.
Negative_regulation (reduces) of myoglobin in thigh
3) Confidence 0.39 Published 2000 Journal Clin J Sport Med Section Body Doc Link 10695845 Disease Relevance 0 Pain Relevance 0
These responses as well as plasma levels of creatine kinase and myoglobin were all attenuated after the repeated eccentric exercise bout (P < 0.05).
Negative_regulation (attenuated) of myoglobin in plasma
4) Confidence 0.34 Published 2008 Journal Eur. J. Appl. Physiol. Section Abstract Doc Link 18340456 Disease Relevance 0.10 Pain Relevance 0
The removal of myoglobin by plasma exchange has not demonstrated any benefit [145].
Negative_regulation (removal) of myoglobin in plasma
5) Confidence 0.21 Published 2005 Journal Crit Care Section Body Doc Link PMC1175909 Disease Relevance 1.55 Pain Relevance 0.03
Values of sodium, myoglobin and LDH decreased.
Negative_regulation (decreased) of myoglobin
6) Confidence 0.15 Published 2003 Journal Dtsch. Med. Wochenschr. Section Body Doc Link 12894392 Disease Relevance 0 Pain Relevance 0
Because of different amounts of H-FABP and myoglobin in myocardial and skeletal muscle tissue a low mioglobin/H-FABP ratio might have myocardial specificity.
Negative_regulation (amounts) of myoglobin in skeletal muscle tissue
7) Confidence 0.07 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.57 Pain Relevance 0.04

General Comments

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