INT100748

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Context Info
Confidence 0.60
First Reported 2002
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 3.58
Pain Relevance 2.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (FOLH1) plasma membrane (FOLH1) nucleus (FOLH1)
cytoplasm (FOLH1)
Anatomy Link Frequency
myocardium 1
coronary artery 1
dorsal horn 1
FOLH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
neuralgia 3 100.00 Very High Very High Very High
nociceptor 1 100.00 Very High Very High Very High
ischemia 12 99.16 Very High Very High Very High
Dorsal horn 3 98.88 Very High Very High Very High
Neuropathic pain 5 98.32 Very High Very High Very High
Inflammation 4 97.80 Very High Very High Very High
allodynia 3 97.44 Very High Very High Very High
Analgesic 1 97.24 Very High Very High Very High
Glutamate 5 95.52 Very High Very High Very High
Neurotransmitter 1 93.12 High High
Disease Link Frequency Relevance Heat
Prostate Cancer 5 99.84 Very High Very High Very High
Coronary Artery Disease 12 99.40 Very High Very High Very High
Cv Unclassified Under Development 14 99.16 Very High Very High Very High
Neuropathic Pain 11 98.32 Very High Very High Very High
INFLAMMATION 4 97.80 Very High Very High Very High
Cancer 3 97.00 Very High Very High Very High
Disease 5 91.92 High High
Hypersensitivity 1 88.84 High High
Coronary Heart Disease 2 83.36 Quite High
Nervous System Injury 2 82.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prostate-specific membrane antigen (PSMA) has been identified as an ideal antigenic target in prostate cancer.
Regulation (target) of PSMA associated with prostate cancer
1) Confidence 0.60 Published 2003 Journal Semin. Oncol. Section Abstract Doc Link 14571414 Disease Relevance 0.72 Pain Relevance 0.09
However, several authors suggest the efficacy of PSM during DSE in coronary artery disease.
Regulation (efficacy) of PSM in coronary artery associated with coronary artery disease
2) Confidence 0.06 Published 2009 Journal Korean Circulation Journal Section Body Doc Link PMC2790124 Disease Relevance 0.86 Pain Relevance 0.12
Although different methods have revealed PSM of the ischemic myocardial segments as regional asynchrony of myocardial wall motion during acute ischemia,9)10) there are a few reports concerning PSM and its diagnostic value for the improvement of dysfunctional myocardium during DSE after successful revascularization.
Regulation (value) of PSM in myocardium associated with ischemia
3) Confidence 0.06 Published 2009 Journal Korean Circulation Journal Section Body Doc Link PMC2790124 Disease Relevance 0.65 Pain Relevance 0.22
In the present study, we determined the effect of a GCP II inhibitor, 2-(phosphono-methyl)-pentanedioic acid (2-PMPA), on allodynia and ectopic afferent discharges in an animal model of neuropathic pain.
Spec (determined) Regulation (effect) of GCP II associated with allodynia and neuropathic pain
4) Confidence 0.05 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11805230 Disease Relevance 1.01 Pain Relevance 1.32
Effects of GCP-II inhibition on responses of dorsal horn neurones after inflammation and neuropathy: an electrophysiological study in the rat.
Regulation (Effects) of GCP-II in dorsal horn associated with neuralgia, inflammation, neuropathic pain and dorsal horn
5) Confidence 0.01 Published 2003 Journal Neuropeptides Section Title Doc Link 14607107 Disease Relevance 0.33 Pain Relevance 1.01

General Comments

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