INT101026

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.35
First Reported 2002
Last Reported 2005
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.01
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs2) oxidoreductase activity (Ptgs2) endoplasmic reticulum (Ptgs2)
nucleus (Ptgs2) enzyme binding (Ptgs2) protein complex (Ptgs2)
Anatomy Link Frequency
brain 2
platelet 2
Ptgs2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 100.00 Very High Very High Very High
COX2 4 100.00 Very High Very High Very High
acular 3 100.00 Very High Very High Very High
cOX1 1 100.00 Very High Very High Very High
Inflammatory response 1 99.80 Very High Very High Very High
cva 7 98.68 Very High Very High Very High
cINOD 11 96.56 Very High Very High Very High
diclofenac 2 75.00 Quite High
Arthritis 1 74.64 Quite High
aspirin 8 48.24 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 9 99.80 Very High Very High Very High
Cv General 3 Under Development 7 98.68 Very High Very High Very High
Disease 2 89.84 High High
Neurodegenerative Disease 1 89.04 High High
Arthritis 1 74.64 Quite High
Urticaria 2 50.00 Quite Low
Myocardial Infarction 3 30.88 Quite Low
Stroke 1 29.04 Quite Low
Hypertension 1 25.00 Low Low
Pressure And Volume Under Development 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been hypothesized that cyclooxygenase 2 specific inhibitors may increase the risk of cardiovascular (CV) thromboembolic events because of their inhibition of vascular prostacyclin synthesis and lack of an effect on platelet thromboxane A(2) production and aggregation.
Spec (may) Positive_regulation (increase) of Negative_regulation (inhibitors) of cyclooxygenase 2 in platelet associated with cva and cox2
1) Confidence 0.35 Published 2002 Journal Am. J. Cardiol. Section Abstract Doc Link 11835924 Disease Relevance 0.40 Pain Relevance 0.43
Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli.
Positive_regulation (increases) of Negative_regulation (inhibition) of Cyclooxygenase 2 in brain associated with inflammatory response and cox2
2) Confidence 0.23 Published 2005 Journal J. Neurochem. Section Title Doc Link 16277613 Disease Relevance 0.62 Pain Relevance 0.80
CONCLUSIONS: Cyclooxygenase 2 inhibitors do not induce urticaria in patients with CIU sensitive to NSAIDs.
Neg (not) Positive_regulation (induce) of Negative_regulation (inhibitors) of Cyclooxygenase 2
3) Confidence 0.07 Published 2003 Journal Arch Dermatol Section Body Doc Link 14676074 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox