INT101049

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Context Info
Confidence 0.67
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 5.71
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CD5) plasma membrane (CD5)
Anatomy Link Frequency
T-cell 1
CD5 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 2 82.72 Quite High
Pain refractory 1 79.52 Quite High
nud 1 79.08 Quite High
Crohn's disease 2 76.76 Quite High
backache 1 75.44 Quite High
transdermal 4 75.20 Quite High
Nicotine 20 74.24 Quite High
abdominal pain 1 71.20 Quite High
vincristine 2 54.56 Quite High
Inflammation 63 48.44 Quite Low
Disease Link Frequency Relevance Heat
Spontaneous Abortion 7 99.88 Very High Very High Very High
Lymphatic System Cancer 18 99.76 Very High Very High Very High
Epstein-barr Virus 1 98.24 Very High Very High Very High
Nicotine Addiction 366 97.48 Very High Very High Very High
Inflammatory Bowel Disease 4 88.44 High High
Cancer 24 87.32 High High
Mantle-cell Lymphoma 7 86.16 High High
Infection 1 84.32 Quite High
Congenital Anomalies 1 81.76 Quite High
Intractable Pain 1 79.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Spontaneous abortions with increased CD5 positive cells in the placental tissue during the first trimester of gestation.
Positive_regulation (increased) of CD5 associated with spontaneous abortion
1) Confidence 0.67 Published 2001 Journal Clin Exp Obstet Gynecol Section Title Doc Link 11838755 Disease Relevance 0.69 Pain Relevance 0
Immunohistochemichally, the cells were positive for CD20, CD79a, CD43 and cyclin D1, but negative for CD3, CD5 and bcl-6.
Positive_regulation (negative) of CD5
2) Confidence 0.46 Published 2004 Journal Leuk. Lymphoma Section Abstract Doc Link 15359648 Disease Relevance 1.40 Pain Relevance 0.19
On immunohistochemistry they were found to be positive for Bcl2, CD20, CD45RB and CD79a, but negative for CD3, CD5, CD10 and cyclin D1.
Positive_regulation (negative) of CD5
3) Confidence 0.40 Published 2008 Journal Pathol. Int. Section Abstract Doc Link 18324920 Disease Relevance 0.58 Pain Relevance 0.23
The lymphoma cells were positive for CD2, CD3, CD5, CD8, and T-cell receptor (TCR) beta F1, but negative for CD4, CD19, CD20, CD103, and CD56.
Positive_regulation (positive) of CD5 in T-cell associated with lymphatic system cancer
4) Confidence 0.15 Published 2003 Journal J. Gastroenterol. Section Abstract Doc Link 12743779 Disease Relevance 0.79 Pain Relevance 0.10
Like sICAM-1, the elevations in CD44v5 and v6, but not total CD44, are dose-dependent and reversible [141].
Positive_regulation (elevations) of CD44v5
5) Confidence 0.01 Published 2003 Journal Tob Induc Dis Section Body Doc Link PMC2669563 Disease Relevance 1.12 Pain Relevance 0.07
Like sICAM-1, the elevations in CD44v5 and v6, but not total CD44, are dose-dependent and reversible [141].
Positive_regulation (elevations) of CD44v5
6) Confidence 0.01 Published 2003 Journal Tob Induc Dis Section Body Doc Link PMC2671531 Disease Relevance 1.12 Pain Relevance 0.07

General Comments

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