INT101067

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Context Info
Confidence 0.21
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK1) mitochondrion (MAPK1) Golgi apparatus (MAPK1)
DNA binding (MAPK1) protein complex (MAPK1) response to stress (MAPK1)
MAP3K15 (Homo sapiens)
MAPK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 13 98.64 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 2 100.00 Very High Very High Very High
Stress 2 79.68 Quite High
Colon Cancer 1 69.28 Quite High
INFLAMMATION 1 52.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mobility on SDS-PAGE of the apoptosis signal-regulating kinase, which activates C-Jun N-terminal kinases and p38 MAPK cascades, was reduced by H(2)O(2) and NSAIDs, suggesting, that H(2)O(2) and NSAIDs activated apoptosis signal-regulating kinase by increasing its state of phosphorylation.
apoptosis signal-regulating kinase Positive_regulation (activates) of p38 associated with cinod and apoptosis
1) Confidence 0.21 Published 2002 Journal Biochem. Pharmacol. Section Abstract Doc Link 11841790 Disease Relevance 0.47 Pain Relevance 1.03

General Comments

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