INT101317

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Context Info
Confidence 0.02
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 3.72
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Selp) nucleolus (Selp) cell adhesion (Selplg)
nucleus (Selp) plasma membrane (Selplg) cytoplasm (Selp)
Anatomy Link Frequency
monocytes 1
platelets 1
endothelium 1
neutrophils 1
Selplg (Mus musculus)
Selp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 16 90.72 High High
Angina 4 82.88 Quite High
Inflammatory response 4 79.00 Quite High
Inflammatory mediators 4 75.00 Quite High
Inflammation 4 70.36 Quite High
Disease Link Frequency Relevance Heat
Adhesions 4 95.40 Very High Very High Very High
Necrosis 4 91.72 High High
Cancer 4 91.36 High High
Acute Coronary Syndrome 4 85.68 High High
Cv General 3 Under Development 4 82.88 Quite High
Myocardial Infarction 4 80.40 Quite High
INFLAMMATION 12 78.64 Quite High
Rupture 4 77.04 Quite High
Disease 8 76.08 Quite High
Cardiovascular Disease 4 71.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to mediating transient interactions between endothelial cells and leukocytes, P-selectin has been reported to mediate adherence of platelets to monocytes and neutrophils via specific interaction with PSGL-1.
PSGL-1 Binding (interaction) of P-selectin in neutrophils
1) Confidence 0.02 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11861775 Disease Relevance 0.95 Pain Relevance 0.26
P-selectin is expressed on activated platelets and endothelium and serves as the receptor for the endogenous ligand, P-selectin glycoprotein-1 (PSGL-1), expressed on various leukocytic cell types.
PSGL-1 Binding (receptor) of P-selectin in endothelium
2) Confidence 0.02 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11861775 Disease Relevance 0.91 Pain Relevance 0.25
In addition to mediating transient interactions between endothelial cells and leukocytes, P-selectin has been reported to mediate adherence of platelets to monocytes and neutrophils via specific interaction with PSGL-1.
PSGL-1 Binding (interaction) of P-selectin in monocytes
3) Confidence 0.01 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11861775 Disease Relevance 0.95 Pain Relevance 0.26
P-selectin is expressed on activated platelets and endothelium and serves as the receptor for the endogenous ligand, P-selectin glycoprotein-1 (PSGL-1), expressed on various leukocytic cell types.
PSGL-1 Binding (receptor) of P-selectin in platelets
4) Confidence 0.01 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11861775 Disease Relevance 0.91 Pain Relevance 0.25

General Comments

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