INT101345

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Context Info
Confidence 0.64
First Reported 2002
Last Reported 2002
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Nsfl1c) cytosol (Nsfl1c) Golgi apparatus (Nsfl1c)
chromosome (Nsfl1c) nucleus (Nsfl1c)
Anatomy Link Frequency
phagocyte 1
Nsfl1c (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 97.40 Very High Very High Very High
Inflammatory response 2 91.72 High High
dexamethasone 2 77.52 Quite High
acular 2 76.16 Quite High
Disease Link Frequency Relevance Heat
Peritonitis 4 99.82 Very High Very High Very High
Neutrophil Disorders 2 98.86 Very High Very High Very High
Leukocytosis 8 97.40 Very High Very High Very High
INFLAMMATION 4 97.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thioglycollate peritonitis in mice lacking C5, 5-lipoxygenase, or p47(phox): complement, leukotrienes, and reactive oxidants in acute inflammation.
Neg (lacking) Gene_expression (lacking) of p47 associated with inflammation and peritonitis
1) Confidence 0.64 Published 2002 Journal J. Leukoc. Biol. Section Title Doc Link 11867678 Disease Relevance 0.63 Pain Relevance 0.09
In the current study, we examined the fate of LTB(4) in the p47(phox-/-) mouse model of chronic granulomatous disease (CGD) in which the phagocyte NADPH oxidase is unable to produce superoxide. p47(phox-/-) mice generated more thioglycollate-elicited peritoneal leukocytosis than wild-type mice.
Gene_expression (produce) of p47 in phagocyte associated with leukocytosis and neutrophil disorders
2) Confidence 0.57 Published 2002 Journal J. Leukoc. Biol. Section Abstract Doc Link 11867678 Disease Relevance 0.67 Pain Relevance 0.19

General Comments

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