INT101364

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Context Info
Confidence 0.06
First Reported 2002
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 1.84
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Inadl) protein complex (Inadl) cytoplasm (Inadl)
Anatomy Link Frequency
neurite 1
Inadl (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 32 90.72 High High
Pain 6 88.32 High High
cytokine 62 88.16 High High
dorsal root ganglion 98 82.88 Quite High
Root ganglion neuron 2 81.48 Quite High
tissue acidosis 2 77.64 Quite High
ASIC 2 66.12 Quite High
Nerve growth factor 20 56.88 Quite High
Spinal cord 24 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 103 99.80 Very High Very High Very High
Targeted Disruption 18 89.04 High High
Pain 6 88.32 High High
Ganglion Cysts 100 81.92 Quite High
Acidosis 2 77.64 Quite High
Nociception 38 74.48 Quite High
Disease 13 72.28 Quite High
Sepsis 52 50.00 Quite Low
Viral Meningitis 6 36.60 Quite Low
INFLAMMATION 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Co-expression of CIPP and ASIC3 in COS cells increases the maximal ASIC3 peak current density by a factor of 5 and slightly shifts the pH(0.5) for activation from pH 6.2 to pH 6.4.
Gene_expression (expression) of CIPP
1) Confidence 0.06 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11872753 Disease Relevance 0.48 Pain Relevance 0.32
Co-expression of CIPP and ASIC3 in COS cells increases the maximal ASIC3 peak current density by a factor of 5 and slightly shifts the pH(0.5) for activation from pH 6.2 to pH 6.4.
Gene_expression (-) of CIPP
2) Confidence 0.06 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11872753 Disease Relevance 0.48 Pain Relevance 0.32
We examined splenocytes isolated from tiger mice for expression of GFP and various cell-surface markers on selected days after WNV infection.
Gene_expression (expression) of after associated with infection
3) Confidence 0.02 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2749443 Disease Relevance 0.60 Pain Relevance 0
In contrast to previously transplanted neurospheres derived from mouse [7] and human [8] forebrain, which did not express any specific neuronal markers after transplantation, in the experiments described here, we achieved differentiation of transplanted cells into neurons with extensive neurite outgrowth into the host dorsal roots and the expression of neuronal markers specific for the nociceptor neuron phenotype.
Neg (not) Gene_expression (express) of after in neurite associated with nociceptor
4) Confidence 0.01 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0.12 Pain Relevance 0.28
The cells were divided in two groups and DOX was added to the medium of one of these groups 24 hours after transfection.
Gene_expression (transfection) of after
5) Confidence 0.01 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0.07 Pain Relevance 0
As seen by RT-PCR Sox10 was initially highly expressed, but this expression declined after 4 to 5 weeks in culture.
Gene_expression (expressed) of after
6) Confidence 0.01 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0.09 Pain Relevance 0
Neurospheres were plated on D-polylysine-laminin coated coverslips 2 days after transfection in a medium without mitogens to allow for differentiation.
Gene_expression (transfection) of after
7) Confidence 0.01 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2733376 Disease Relevance 0 Pain Relevance 0
After exposing to X-ray film, the relative signal intensity was determined using the NIH image 1.59 software, and expressed as % of positive controls on the same membrane.


Gene_expression (expressed) of After
8) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2048740 Disease Relevance 0 Pain Relevance 0.17

General Comments

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