INT101441

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Context Info
Confidence 0.54
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 15
Total Number 17
Disease Relevance 7.03
Pain Relevance 3.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FTH1) mitochondrion (FTH1) oxidoreductase activity (FTH1)
transmembrane transport (FTH1)
Anatomy Link Frequency
anterior 2
spine 2
spinal 1
Poly 1
FHC 1
FTH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
spondylitis 16 99.46 Very High Very High Very High
backache 92 99.02 Very High Very High Very High
Pain 112 94.64 High High
iatrogenic 8 84.64 Quite High
imagery 14 84.16 Quite High
Angina 1 52.76 Quite High
Sciatica 5 48.32 Quite Low
Perioperative pain 5 48.00 Quite Low
anesthesia 2 7.68 Low Low
Facet joint 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Hypertrophic Cardiomyopathy 6 100.00 Very High Very High Very High
Osteoporosis 2 99.96 Very High Very High Very High
Pathologic Constriction 48 99.76 Very High Very High Very High
Nerve Root Compression 11 99.62 Very High Very High Very High
Rheumatoid Arthritis 10 99.46 Very High Very High Very High
Low Back Pain 107 99.02 Very High Very High Very High
Ankylosing Spondylitis 6 98.38 Very High Very High Very High
Disease 28 96.52 Very High Very High Very High
Pain 112 94.64 High High
Syndrome 5 94.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Twenty-seven patients underwent a PLIF using one single fusion cage (BAK, Sulzer Spine-Tech, Minneapolis, MN, USA) inserted posterolaterally and oriented anteromedially on the symptomatic side with unilateral facetectomy and at the same level supplemental fixation with a transpedicular screw/rod system.
Positive_regulation (underwent) of PLIF in Spine
1) Confidence 0.54 Published 2003 Journal Eur Spine J Section Abstract Doc Link 12709855 Disease Relevance 0.24 Pain Relevance 0.05
MATERIAL: The authors performed a retrospective analysis on a group of 91 patients (49 females, 42 males) with isthmic, degenerative or dysplastic spondylolisthesis at the L4-L5 level who had undergone the PLIF technique on L4/L5 or L5/S1 with transpedicular fixation surgery and PLF in the period from 1990 to 2001.
Positive_regulation (undergone) of PLIF
2) Confidence 0.49 Published 2010 Journal Acta Chir Orthop Traumatol Cech Section Body Doc Link 20447355 Disease Relevance 0.09 Pain Relevance 0
Eighty-nine (55 male, 34 female) patients underwent PLIF with a presized, machined allograft spacer and posterior pedicle fixation between January 2000 and April 2003.
Positive_regulation (underwent) of PLIF in posterior
3) Confidence 0.40 Published 2009 Journal Am J. Orthop. Section Abstract Doc Link 19714280 Disease Relevance 0.50 Pain Relevance 0.26
The graft-related complication rate among all patients who underwent PLIF was 1.61%.
Positive_regulation (underwent) of PLIF
4) Confidence 0.40 Published 2009 Journal Am J. Orthop. Section Abstract Doc Link 19714280 Disease Relevance 0.63 Pain Relevance 0.65
Between July 1997 and December 2003, 75 patients underwent PLIF with cages and IPLF with transpedicular instrumentation, for either degenerative disc disease, stenosis, spondylolisthesis or post-discectomy syndrome.
Positive_regulation (underwent) of PLIF associated with low back pain, pathologic constriction, syndrome and disease
5) Confidence 0.40 Published 2008 Journal Acta Orthop Belg Section Abstract Doc Link 18564483 Disease Relevance 0.38 Pain Relevance 0
CONCLUSIONS: Pseudarthrosis should be considered in the differential diagnosis if severe symptoms persist in patients who undergo PLIF with stand-alone metallic cages.
Positive_regulation (undergo) of PLIF
6) Confidence 0.40 Published 2006 Journal Spine J Section Body Doc Link 16825051 Disease Relevance 0 Pain Relevance 0
PLIF with spinal instruments is a preferred treatment for rheumatoid spondylitis of the lumbar spine, but in the mutilating type of RA with severe osteoporosis, PLIF in combination with a long fixation system and/or augmentation of the vertebral bodies might be needed.
Positive_regulation (augmentation) of PLIF in spinal associated with spondylitis, ankylosing spondylitis and osteoporosis
7) Confidence 0.37 Published 2002 Journal Arch Orthop Trauma Surg Section Abstract Doc Link 11880906 Disease Relevance 0.71 Pain Relevance 0.42
We performed posterior lumbar interbody fusion (PLIF) on 7 patients with rheumatoid spondylitis (RA) of the lumbar spine with severe low-back pain and/or cauda equina symptoms, and evaluated the effectiveness of PLIF for the lumbar spinal instability in RA secondary to destruction of the anterior elements, including vertebral endplates and the apophyseal joint.
Positive_regulation (effectiveness) of PLIF in spine associated with spondylitis, ankylosing spondylitis and backache
8) Confidence 0.37 Published 2002 Journal Arch Orthop Trauma Surg Section Abstract Doc Link 11880906 Disease Relevance 0.71 Pain Relevance 0.54
Forty-one patients underwent a single-level PLIF with a unilateral approach in our hospital between March 1999 and March 2001.
Positive_regulation (underwent) of PLIF
9) Confidence 0.35 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2688150 Disease Relevance 0.58 Pain Relevance 0.64
A total of 41 patients underwent a single-level PLIF using two PEEKĀ™ (Poly-Ether-Ether-Ketone) cages filled with iliac bone, via a unilateral approach.
Positive_regulation (underwent) of PLIF in Poly
10) Confidence 0.35 Published 2006 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2688150 Disease Relevance 0.56 Pain Relevance 0.38
The results of these studies will lead to a better understanding of FHC and eventually identify targets for therapeutic intervention.
Positive_regulation (understanding) of FHC in FHC associated with familial hypertrophic cardiomyopathy
11) Confidence 0.33 Published 2005 Journal Heart Fail Rev Section Abstract Doc Link 16416046 Disease Relevance 0.77 Pain Relevance 0.05
A direct comparison of anterior lumbar interbody fusion (ALIF) with anterior tension band plating to that of instrumented PLIF has not been previously reported.
Positive_regulation (instrumented) of PLIF in anterior
12) Confidence 0.29 Published 2009 Journal Orthopedics Section Abstract Doc Link 19634851 Disease Relevance 0.30 Pain Relevance 0.09
This retrospective uncontrolled cohort comparison included 59 patients with low back pain and 1- or 2-level lumbar degenerative disk disease from L3 to S1 who underwent PLIF with pedicle screw instrumentation or ALIF with anterior tension band plating.
Positive_regulation (underwent) of PLIF in anterior associated with nerve root compression, low back pain and backache
13) Confidence 0.23 Published 2009 Journal Orthopedics Section Abstract Doc Link 19634851 Disease Relevance 0.36 Pain Relevance 0.10
MATERIALS AND METHODS: Eighty-seven patients who underwent PLIF for L4 degenerative spondylolisthesis and could be followed for at least 2 years were included in this study.
Positive_regulation (underwent) of PLIF
14) Confidence 0.09 Published 2004 Journal Spine Section Body Doc Link 15247575 Disease Relevance 0.07 Pain Relevance 0
In the congenital stenosis groups, we performed PLIF for 3 patients and microsurgical discectomy for 4 patients.


Positive_regulation (performed) of PLIF associated with pathologic constriction
15) Confidence 0.08 Published 2005 Journal Yonsei Medical Journal Section Body Doc Link PMC2823038 Disease Relevance 0.67 Pain Relevance 0
Especially for the 22 disc extruded patients, we performed PLIF for 3 patients, microsurgical discectomy for 7 patients, and chemonucleolysis for 12 patients.
Positive_regulation (performed) of PLIF
16) Confidence 0.08 Published 2005 Journal Yonsei Medical Journal Section Body Doc Link PMC2823038 Disease Relevance 0.41 Pain Relevance 0.05
In our study, the failed chemonucleolysis patients received reoperations; 5 patients underwent microsurgical discectomy and 2 patients underwent PLIF with cages.
Positive_regulation (underwent) of PLIF
17) Confidence 0.07 Published 2005 Journal Yonsei Medical Journal Section Body Doc Link PMC2823038 Disease Relevance 0.06 Pain Relevance 0

General Comments

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