INT101476

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.24
First Reported 2002
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.04
Pain Relevance 1.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (P2rx6)
Anatomy Link Frequency
sensory neurons 1
brain 1
microglia 1
P2rx6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 11 100.00 Very High Very High Very High
medulla 6 100.00 Very High Very High Very High
cerebral cortex 3 100.00 Very High Very High Very High
Thalamus 1 100.00 Very High Very High Very High
adenocard 22 99.80 Very High Very High Very High
Hyperalgesia 2 99.76 Very High Very High Very High
Neurotransmitter 25 99.58 Very High Very High Very High
c fibre 3 99.48 Very High Very High Very High
agonist 7 99.04 Very High Very High Very High
Neuropeptide 18 90.08 High High
Disease Link Frequency Relevance Heat
Hyperalgesia 2 99.76 Very High Very High Very High
Nociception 2 97.48 Very High Very High Very High
Ganglion Cysts 37 86.80 High High
Nervous System Injury 8 85.44 High High
Targeted Disruption 5 41.44 Quite Low
Injury 4 20.40 Low Low
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Coronary Heart Disease 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Simultaneously with glia activation, hyperalgesia was observed, but the expression of P2X4 receptor, which is considered to be closely associated with hyperalgesia, on microglia was not detected.
P2X4 receptor Binding (associated) of in microglia associated with hyperalgesia
1) Confidence 0.24 Published 2005 Journal Neuroreport Section Abstract Doc Link 16110278 Disease Relevance 0.20 Pain Relevance 0.32
The P2X4 receptor shows substantial expression in several brain areas such as the cerebral cortex, hippocampus, thalamus, and brainstem [70] and is associated with postsynaptic specialization of synaptic contacts [62].
P2X4 receptor Binding (associated) of in brain associated with medulla, thalamus, hippocampus and cerebral cortex
2) Confidence 0.12 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072919 Disease Relevance 0 Pain Relevance 0.29
The latter responded to both P2X receptor and adenosine receptor agonists.
P2X receptor Binding (responded) of associated with adenocard and agonist
3) Confidence 0.07 Published 2002 Journal Neuroscience Section Abstract Doc Link 11882377 Disease Relevance 0 Pain Relevance 0.62
Cross-excitation occurs via non-synaptic neurotransmitters, such as ATP, which binds the P2X3 receptor, an ATP-gated cation channel receptor associated with primary nociceptive sensory neurons.
P2X3 receptor Binding (binds) of in sensory neurons associated with nociception and neurotransmitter
4) Confidence 0.01 Published 2006 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC1790972 Disease Relevance 0.84 Pain Relevance 0.56

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox