INT101495

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Context Info
Confidence 0.26
First Reported 2002
Last Reported 2006
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.88
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (F2rl1) signal transducer activity (F2rl1)
Anatomy Link Frequency
hearts 2
F2rl1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 8 96.72 Very High Very High Very High
ischemia 2 94.92 High High
agonist 4 87.68 High High
qutenza 4 85.20 High High
nociceptor 8 81.76 Quite High
c fibre 3 75.00 Quite High
trigeminal ganglion 6 73.60 Quite High
neuropeptide release 2 56.80 Quite High
Potency 1 51.12 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 1 99.40 Very High Very High Very High
Injury 3 95.92 Very High Very High Very High
Coronary Artery Disease 1 94.92 High High
Increased Venous Pressure Under Development 3 80.08 Quite High
Cv Unclassified Under Development 1 75.00 Quite High
Reperfusion Injury 1 75.00 Quite High
Ganglion Cysts 6 72.72 Quite High
Facial Pain 1 25.00 Low Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we investigated the effects of PAR2 activation on coronary tone in isolated perfused rat hearts and elucidated the mechanisms of any observed effects.
Spec (investigated) Regulation (effects) of Spec (investigated) Positive_regulation (activation) of PAR2 in hearts
1) Confidence 0.26 Published 2002 Journal Circ. Res. Section Abstract Doc Link 11884377 Disease Relevance 0.57 Pain Relevance 0.19
The role of protease activated receptor-2 (PAR-2) activation in trigeminal nociception and in induction of functional competence in the delta opioid receptor (DOR) is not known.
Regulation (role) of Positive_regulation (activation) of PAR-2 associated with nociception and opioid receptor
2) Confidence 0.24 Published 2006 Journal Pain Section Abstract Doc Link 16781076 Disease Relevance 0.31 Pain Relevance 0.72

General Comments

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