INT101551

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Context Info
Confidence 0.07
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.51
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (CACNA1A, CACNA1F) small molecule metabolic process (CACNA1A) cell death (CACNA1A)
plasma membrane (CACNA1A) nucleus (CACNA1A) cytoplasm (CACNA1A)
CACNA1A (Homo sapiens)
CACNA1F (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 1 100.00 Very High Very High Very High
Calcium channel 4 98.24 Very High Very High Very High
Central nervous system 2 93.96 High High
Disease Link Frequency Relevance Heat
Ataxia 4 100.00 Very High Very High Very High
Neurological Disease 3 100.00 Very High Very High Very High
Spinocerebellar Ataxia Type 2 1 100.00 Very High Very High Very High
Migraine With Aura 1 100.00 Very High Very High Very High
Night Blindness 1 99.30 Very High Very High Very High
Disease 3 97.50 Very High Very High Very High
Channelopathies 3 92.76 High High
Absence Epilepsy 2 80.96 Quite High
Convulsion 1 75.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The human diseases comprise: 1) a recessive retinal disorder, X-linked congenital stationary night blindness, associated with mutations in the CACNA1F gene, encoding alpha(1)1.4 subunits of L-type channels; and 2) a group of rare allelic autosomal dominant human neurological disorders including familial hemiplegic migraine, episodic ataxia type 2, and spinocerebellar ataxia type 6, all associated with mutations in the CACNA1A gene, encoding alpha(1)2.1 subunits of P/Q-type calcium channels.
CACNA1A gene Binding (associated) of CACNA1F gene associated with ataxia, neurological disease, calcium channel, migraine, spinocerebellar ataxia type 2, night blindness, disease and migraine with aura
1) Confidence 0.07 Published 2002 Journal Mol. Neurobiol. Section Abstract Doc Link 11890456 Disease Relevance 1.51 Pain Relevance 0.33

General Comments

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