INT101555

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Context Info
Confidence 0.45
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.91
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Nt5e) cytoplasm (Nt5e)
Anatomy Link Frequency
endothelial cells 1
spinal cord 1
brain 1
Nt5e (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 8 99.32 Very High Very High Very High
Hippocampus 3 95.36 Very High Very High Very High
Inflammation 42 89.80 High High
cva 73 88.76 High High
ischemia 1 83.16 Quite High
Multiple sclerosis 2 82.04 Quite High
Central nervous system 2 77.12 Quite High
chemokine 15 76.80 Quite High
Inflammatory mediators 11 72.40 Quite High
Pain 2 72.36 Quite High
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 10 99.90 Very High Very High Very High
Stress 20 99.44 Very High Very High Very High
Pneumonia 15 89.80 High High
Subarachnoid Hemorrhage 70 88.76 High High
Brain Hemorrhage 1 83.16 Quite High
Demyelinating Disease 2 82.04 Quite High
Disease 6 80.88 Quite High
INFLAMMATION 45 78.56 Quite High
Adhesions 18 73.56 Quite High
Pain 2 72.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gallic acid treatment significantly attenuated some alterations (i.e. increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, 5'-nucleotidase, bilirubin, alpha-fetoprotein, carcinoembryonic antigen) and decreased the levels of argyophillic nucleolar organizing regions (AgNORs) and proliferating cell nuclear antigen (PCNA) [90].
Positive_regulation (increased) of 5'-nucleotidase
1) Confidence 0.45 Published 2010 Journal J Transl Med Section Body Doc Link PMC2991329 Disease Relevance 0.06 Pain Relevance 0
There was an increase in the 5'-nucleotidase activity in the same group.
Positive_regulation (increase) of nucleotidase
2) Confidence 0.34 Published 2002 Journal Physiol. Behav. Section Abstract Doc Link 11890946 Disease Relevance 0.78 Pain Relevance 0.34
NTPDase and 5'-nucleotidase activities from brain and serum were significantly increased in the homocysteine-treated group.
Positive_regulation (increased) of nucleotidase in brain
3) Confidence 0.32 Published 2004 Journal Neurochem. Res. Section Abstract Doc Link 15202768 Disease Relevance 0.20 Pain Relevance 0.30
Chronic stress reduced ADP hydrolysis and increased 5'-nucleotidase activity in the spinal cord in male rats.
Positive_regulation (increased) of nucleotidase in spinal cord associated with stress and spinal cord
4) Confidence 0.25 Published 2002 Journal Physiol. Behav. Section Abstract Doc Link 11890946 Disease Relevance 0.74 Pain Relevance 0.31
treatment ameliorated vascular leakage in ALI via upregulation of 5'-nucleotidase (CD73) on pulmonary endothelial cells [25].
Positive_regulation (upregulation) of nucleotidase in endothelial cells associated with adult respiratory distress syndrome
5) Confidence 0.03 Published 2010 Journal Crit Care Section Body Doc Link PMC2945141 Disease Relevance 1.12 Pain Relevance 0.45

General Comments

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