INT101566

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Context Info
Confidence 0.35
First Reported 2002
Last Reported 2006
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.28
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ctnnb1) enzyme binding (Ctnnb1) DNA binding (Ctnnb1)
protein complex (Ctnnb1) cytoplasm (Ctnnb1) cell proliferation (Ctnnb1)
Ctnnb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 9 99.16 Very High Very High Very High
Inflammation 3 97.96 Very High Very High Very High
antagonist 1 96.76 Very High Very High Very High
aspirin 8 87.00 High High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 97.96 Very High Very High Very High
Rheumatoid Arthritis 3 97.08 Very High Very High Very High
Aberrant Crypt Foci 14 96.68 Very High Very High Very High
Cancer 7 96.36 Very High Very High Very High
Colon Cancer 5 89.16 High High
Colitis 1 83.32 Quite High
Malignant Neoplastic Disease 2 75.00 Quite High
Body Weight 1 54.96 Quite High
Carcinoma 1 41.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, we examined the expression and the localization of beta-catenin protein, and the proliferating cell nuclear antigen (PCNA)-labeling index (LI) in ACF and cancer.
Spec (examined) Negative_regulation (examined) of Spec (examined) Gene_expression (expression) of beta-catenin associated with aberrant crypt foci and cancer
1) Confidence 0.35 Published 2002 Journal Int. J. Mol. Med. Section Abstract Doc Link 11891526 Disease Relevance 1.75 Pain Relevance 0.42
Nitric oxide synthase 2 (NOS-2) activity and beta-catenin expression were suppressed in animals given NO-NSAID.
Negative_regulation (suppressed) of Gene_expression (expression) of beta-catenin associated with cinod
2) Confidence 0.29 Published 2006 Journal Mol. Cancer Ther. Section Abstract Doc Link 16818512 Disease Relevance 0.53 Pain Relevance 0.46

General Comments

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