INT101632

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Context Info
Confidence 0.40
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 0
Pain Relevance 1.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SST) extracellular region (SST) cell-cell signaling (SST)
SST (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 5 100.00 Very High Very High Very High
opioid receptor 10 81.96 Quite High
Somatostatin 15 80.52 Quite High
agonist 5 62.92 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, exposure of the sst(2A)-MOR1 heterodimer to the mu-selective ligand [d-Ala(2),Me-Phe(4),Gly(5)-ol]enkephalin induced phosphorylation and desensitization of both MOR1 and sst(2A) but not internalization of sst(2A).
Positive_regulation (induced) of Phosphorylation (osphorylation a) of sst associated with enkephalin
1) Confidence 0.40 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11896051 Disease Relevance 0 Pain Relevance 0.30
Similarly, exposure of the sst(2A)-MOR1 heterodimer to the mu-selective ligand [d-Ala(2),Me-Phe(4),Gly(5)-ol]enkephalin induced phosphorylation and desensitization of both MOR1 and sst(2A) but not internalization of sst(2A).
Positive_regulation (induced) of Phosphorylation (phosphorylation) of sst associated with enkephalin
2) Confidence 0.40 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11896051 Disease Relevance 0 Pain Relevance 0.31
However, exposure of the sst(2A)-MOR1 heterodimer to the sst(2A)-selective ligand L-779,976 induced phosphorylation, internalization, and desensitization of sst(2A) as well as MOR1.
Positive_regulation (induced) of Phosphorylation (osphorylation, ) of sst
3) Confidence 0.40 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11896051 Disease Relevance 0 Pain Relevance 0.31
However, exposure of the sst(2A)-MOR1 heterodimer to the sst(2A)-selective ligand L-779,976 induced phosphorylation, internalization, and desensitization of sst(2A) as well as MOR1.
Positive_regulation (induced) of Phosphorylation (phosphorylation) of sst
4) Confidence 0.40 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11896051 Disease Relevance 0 Pain Relevance 0.31
Similarly, exposure of the sst(2A)-MOR1 heterodimer to the mu-selective ligand [d-Ala(2),Me-Phe(4),Gly(5)-ol]enkephalin induced phosphorylation and desensitization of both MOR1 and sst(2A) but not internalization of sst(2A).
Positive_regulation (duced p) of Phosphorylation (osphorylation a) of sst associated with enkephalin
5) Confidence 0.37 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 11896051 Disease Relevance 0 Pain Relevance 0.30

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