INT101923

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Context Info
Confidence 0.48
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 5.44
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (MICA) plasma membrane (MICA) cytoplasm (MICA)
Anatomy Link Frequency
skin 3
epithelial cells 1
MICA (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 51 98.92 Very High Very High Very High
Arthritis 89 95.08 Very High Very High Very High
melanocortin 1 receptor 3 93.68 High High
rheumatoid arthritis 11 88.24 High High
Inflammation 18 81.76 Quite High
Crohn's disease 1 44.24 Quite Low
fibrosis 1 5.76 Low Low
agonist 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 48 99.12 Very High Very High Very High
Psoriasis 51 98.92 Very High Very High Very High
Mrsa Infection 4 97.20 Very High Very High Very High
Seronegative Spondarthritis 73 95.08 Very High Very High Very High
Genetic Predisposition To Disease 5 91.64 High High
Rheumatoid Arthritis 11 88.24 High High
Papillomavirus Infection 9 87.52 High High
Stress 9 87.44 High High
Staphylococcus Infection 1 86.88 High High
Pulmonary Disease 87 86.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To evaluate the possible association of MICA gene polymorphism with the risk for nonmelanoma skin cancer we evaluated 153 cases with squamous cell carcinoma, 261 cases with basal cell carcinoma, 111 controls with malignant melanoma, and 247 controls without a history of skin cancer.
MICA gene Binding (association) of in skin associated with skin cancer
1) Confidence 0.48 Published 2002 Journal J. Invest. Dermatol. Section Abstract Doc Link 11918717 Disease Relevance 0.73 Pain Relevance 0
We therefore specifically addressed the possible association between MICA 5.1 homozygosity and skin cancer, as these individuals are expected to be at the highest risk for skin cancer if the MICA gene plays a role in skin carcinogenesis.
MICA Binding (association) of in skin associated with skin cancer
2) Confidence 0.37 Published 2002 Journal J. Invest. Dermatol. Section Abstract Doc Link 11918717 Disease Relevance 1.14 Pain Relevance 0
Therefore, we conclude that an association between MICA gene polymorphism and nonmelanoma skin cancer is not likely.
MICA gene Binding (association) of in skin associated with skin cancer
3) Confidence 0.33 Published 2002 Journal J. Invest. Dermatol. Section Abstract Doc Link 11918717 Disease Relevance 1.00 Pain Relevance 0.09
Association with 2 genes, MICA and the TNF-?
MICA Binding (Association) of
4) Confidence 0.28 Published 2002 Journal Arthritis Res Section Body Doc Link PMC128931 Disease Relevance 1.63 Pain Relevance 0.62
The activating function of NKG2 D is triggered by binding to MHC class 1 chain-related (MIC) molecules A and B, expressed on surface of stressed epithelial cells.
MHC class 1 chain-related Binding (binding) of in epithelial cells
5) Confidence 0.13 Published 2010 Journal Respir Res Section Abstract Doc Link PMC2955660 Disease Relevance 0.68 Pain Relevance 0
In each instance, besifloxacin had the highest AUC0–24 h:MIC90 ratio for all Staphylococcus organisms.
MIC90 Binding (ratio) of
6) Confidence 0.05 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2861941 Disease Relevance 0.26 Pain Relevance 0

General Comments

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