INT101926

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.28
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.39
Pain Relevance 1.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Drd2) signal transduction (Drd2) oxidoreductase activity (Dio1)
endoplasmic reticulum (Dio1) plasma membrane (Drd2) signal transducer activity (Drd2)
Dio1 (Mus musculus)
Drd2 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 99 100.00 Very High Very High Very High
antagonist 31 100.00 Very High Very High Very High
mu opioid receptor 3 96.68 Very High Very High Very High
cocaine 5 94.32 High High
Hippocampus 10 92.20 High High
Enkephalin 2 87.84 High High
dopamine receptor 8 85.04 High High
agonist 28 83.60 Quite High
Eae 1 71.76 Quite High
Catechol-O-methyltransferase 27 52.88 Quite High
Disease Link Frequency Relevance Heat
Sprains And Strains 57 83.00 Quite High
Catalepsy 1 66.32 Quite High
Targeted Disruption 4 63.20 Quite High
Aggression 2 55.92 Quite High
Cognitive Disorder 6 54.08 Quite High
Ganglion Cysts 26 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Dislocations 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, dopamine D1 and D2 receptor binding was measured.
D1 Binding (binding) of D2 receptor associated with dopamine
1) Confidence 0.28 Published 2002 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 11919654 Disease Relevance 0 Pain Relevance 0.57
We have evaluated the functional interaction between the D1 and D2 DA receptor subtypes at the cellular and behavioral levels.
D1 Binding (interaction) of D2 DA receptor associated with dopamine
2) Confidence 0.10 Published 2002 Journal J. Chem. Neuroanat. Section Abstract Doc Link 12048106 Disease Relevance 0.13 Pain Relevance 0.50
The Comt variant causes downstream differences in the expression of genes involved in synaptic function, and also modulates phenotypes such as dopamine D1 and D2 receptor binding and pharmacological responses to haloperidol.


D1 Binding (binding) of D2 associated with dopamine
3) Confidence 0.04 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2923157 Disease Relevance 0.26 Pain Relevance 0.15
Pretreating retinal explants with the D1 antagonist SCH-23390 and the D2 receptor antagonist sulpiride (50 ?
D1 Binding (explants) of D2 receptor associated with antagonist
4) Confidence 0.02 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2567003 Disease Relevance 0 Pain Relevance 0.44

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox