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Context Info
Confidence 0.14
First Reported 2002
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 5.18
Pain Relevance 3.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Rorb) cellular_component (Rorb)
Anatomy Link Frequency
poly 1
brainstem 1
ovary 1
Rorb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cocaine 14 99.60 Very High Very High Very High
Inflammation 103 98.56 Very High Very High Very High
medulla 2 98.56 Very High Very High Very High
antagonist 18 95.96 Very High Very High Very High
Lasting pain 3 95.84 Very High Very High Very High
mu opioid receptor 80 95.24 Very High Very High Very High
agonist 16 93.60 High High
Cannabinoid receptor 3 92.52 High High
withdrawal 15 91.64 High High
Inflammatory mediators 3 90.96 High High
Disease Link Frequency Relevance Heat
Injury 102 99.84 Very High Very High Very High
INFLAMMATION 146 98.56 Very High Very High Very High
Polycystic Ovary Syndrome 6 98.20 Very High Very High Very High
Stress 8 97.44 Very High Very High Very High
Recurrence 5 97.20 Very High Very High Very High
Adhesions 16 96.56 Very High Very High Very High
Pain 8 95.84 Very High Very High Very High
Aging 2 92.08 High High
Apoptosis 47 89.68 High High
Nephrotoxicity 1 88.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Western blot analysis showed no change either on poly-ADP ribose polymerase (PARP) or p53 transcription factor in CCI and sham rats.
Neg (no) Regulation (change) of p53 transcription factor in poly associated with injury
1) Confidence 0.14 Published 2002 Journal Neuroreport Section Abstract Doc Link 11924868 Disease Relevance 1.10 Pain Relevance 0.44
Analysis of transcription factor regulation was performed on each cluster to identify potential mechanisms of regulation for the identified genes and ontologies.

Regulation (regulation) of transcription factor
2) Confidence 0.10 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2900267 Disease Relevance 0 Pain Relevance 0
Transcription factor modulation and expression in the rat auditory brainstem following electrical intracochlear stimulation.
Regulation (modulation) of Transcription factor in brainstem associated with medulla
3) Confidence 0.07 Published 2002 Journal Exp. Neurol. Section Title Doc Link 12009775 Disease Relevance 0 Pain Relevance 0.16
Both the cytoprotective and anti-inflammatory activity of CO appear to result, at least in part, from its ability to modulate the transcription factor NF-?
Regulation (modulate) of transcription factor associated with inflammation
4) Confidence 0.04 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2873601 Disease Relevance 1.01 Pain Relevance 0.17
have been shown to restore ovulation in some women with PCOS [14] and can improve oocyte quality in mice [48], it is important to understand how this transcription factor is regulated in the ovary.

Regulation (regulated) of transcription factor in ovary associated with polycystic ovary syndrome
5) Confidence 0.01 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2795759 Disease Relevance 0.10 Pain Relevance 0.12
In this manner, repeated elements or sequences not predicted to be substrates for transcription factor binding/regulation could be eliminated from testing and analysis, if desired.
Regulation (regulation) of transcription factor
6) Confidence 0.01 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2765473 Disease Relevance 0.06 Pain Relevance 0
Effect on transcription factor FosB
Regulation (Effect) of transcription factor
7) Confidence 0.00 Published 2007 Journal Indian Journal of Psychiatry Section Body Doc Link PMC2917090 Disease Relevance 0.74 Pain Relevance 1.57
There is also evidence that BC supplementation can result in a changed regulation of the transcription factor retinoic acid receptor (RAR) [15].
Regulation (regulation) of transcription
8) Confidence 0.00 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2877315 Disease Relevance 0.91 Pain Relevance 0
B-regulated transcription of iNOS, COX-2, IL-1?
Regulation (regulated) of transcription
9) Confidence 0.00 Published 2007 Journal PPAR Research Section Body Doc Link PMC1950239 Disease Relevance 1.18 Pain Relevance 0.36
A recent study reported that the transcription levels of the several NRSF target genes containing GC-rich regions were decreased with mithramycin A in a dose-dependent manner in both ?
Regulation (target) of transcription
10) Confidence 0.00 Published 2006 Journal Nucleic Acids Research Section Body Doc Link PMC1702488 Disease Relevance 0.08 Pain Relevance 0.35

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