INT102018

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Context Info
Confidence 0.34
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.88
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Atf6b) nucleus (Atf6b) intracellular (Atf6b)
DNA binding (Atf6b)
Atf6b (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 2 100.00 Very High Very High Very High
antidepressant 16 99.34 Very High Very High Very High
depression 2 96.96 Very High Very High Very High
Desipramine 2 77.44 Quite High
fluoxetine 2 76.16 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 6 99.12 Very High Very High Very High
Depression 4 96.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent studies have demonstrated that long-term antidepressant treatment resulted in sustained activation of the cyclic adenosine 3',5'-monophosphate system and in increased expression of the transcription factor cAMP response element binding protein (CREB).
Positive_regulation (increased) of Gene_expression (expression) of cAMP response element binding protein associated with adenocard and antidepressant
1) Confidence 0.34 Published 2002 Journal Neuropsychopharmacology Section Abstract Doc Link 11927185 Disease Relevance 0.44 Pain Relevance 0.50
Recent studies have demonstrated that long-term antidepressant treatment resulted in sustained activation of the cyclic adenosine 3',5'-monophosphate system and in increased expression of the transcription factor cAMP response element binding protein (CREB).
Positive_regulation (activation) of Gene_expression (expression) of cAMP response element binding protein associated with adenocard and antidepressant
2) Confidence 0.34 Published 2002 Journal Neuropsychopharmacology Section Abstract Doc Link 11927185 Disease Relevance 0.44 Pain Relevance 0.50

General Comments

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