INT102070

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Context Info
Confidence 0.60
First Reported 2002
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.68
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Myc) DNA binding (Myc) protein complex (Myc)
cytoplasm (Myc) pigmentation (Myc) chromosome organization (Myc)
Anatomy Link Frequency
colon 4
epidermis 2
Myc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 8 100.00 Very High Very High Very High
endometriosis 46 94.80 High High
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
pain pelvic 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 6 100.00 Very High Very High Very High
Disease 23 97.52 Very High Very High Very High
INFLAMMATION 3 97.12 Very High Very High Very High
Endometriosis 48 94.80 High High
Colon Cancer 2 94.60 High High
Bullous Skin Disease 304 93.68 High High
Adhesions 51 90.68 High High
Apoptosis 57 89.60 High High
Death 9 89.08 High High
Shock 2 74.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The altered expression of c-myc, TGF-?
Regulation (altered) of Gene_expression (expression) of c-myc
1) Confidence 0.60 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1262771 Disease Relevance 1.46 Pain Relevance 0.21
The aim of this study was to examine the effects of NSAIDs on the expression of the tumor suppressor APC gene and the c-myc oncogene in the colons of rats treated with a colon-specific carcinogen, azoxymethane (AOM).
Regulation (effects) of Gene_expression (expression) of c-myc in colon associated with cancer and cinod
2) Confidence 0.44 Published 2002 Journal J. Gastroenterol. Section Abstract Doc Link 11931531 Disease Relevance 0.29 Pain Relevance 0.38
Effects of cyclooxygenase-2 inhibitor NS-398 on APC and c-myc expression in rat colon carcinogenesis induced by azoxymethane.
Regulation (Effects) of Gene_expression (expression) of c-myc in colon
3) Confidence 0.44 Published 2002 Journal J. Gastroenterol. Section Title Doc Link 11931531 Disease Relevance 0.28 Pain Relevance 0.37
In the epidermis, Rac 1 was found not to be crucial for maintaining epithelial integrity but for stem cell differentiation, presumably via negative regulation of c-Myc expression (Benitah et al. 2005; Chrostek et al. 2006).
Regulation (regulation) of Gene_expression (expression) of c-Myc in epidermis
4) Confidence 0.26 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.65 Pain Relevance 0

General Comments

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