INT1021

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Context Info
Confidence 0.69
First Reported 1976
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.59
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pxk) nucleus (Pxk) molecular_function (Pxk)
cellular_component (Pxk) biological_process (Pxk) cytoplasm (Pxk)
Anatomy Link Frequency
trigeminal ganglion 3
ascending limbs 1
Pxk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 3 84.12 Quite High
Morphine 1 80.20 Quite High
Migraine 8 50.00 Quite Low
antagonist 3 11.52 Low Low
isoflurane 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
bradykinin 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Renal Failure 124 92.16 High High
Headache 8 78.60 Quite High
Hypertrophy 11 55.80 Quite High
Natriuresis 2 40.96 Quite Low
Uremia 4 5.00 Very Low Very Low Very Low
Fibrosis 1 5.00 Very Low Very Low Very Low
Disorders Of Creatine Metabolism 1 5.00 Very Low Very Low Very Low
Bartter Syndrome 1 5.00 Very Low Very Low Very Low
Hypercalcemia 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: The mRNA and protein expression levels and activity of P-type Na+ -K+ -ATPase in the trigeminal ganglion and trigeminocervical complex of the model group were 0.72 +/- 0.05, 0.59 +/- 0.05, and 5.21 +/- 0.51 respectively, and the mRNA and protein expression levels and activity of P-type Na+ -K+ -ATPase in the cortex of frontal lobe of the model group were 0.70 +/- 0.05, 0.60 +/- 0.05, and 3.61 +/- 0.49 respectively, all significantly lower than those of the control group (0.83 +/- 0.10, 0.67 +/- 0.06, 6.53 +/- 0.73, 0.81 +/- 0.08, 0.71 +/- 0.09, and 6.61 +/- 0.73 respectively, all P < 0.05).
Transcription (levels) of P-type Na+ -K+ -ATPase in trigeminal ganglion
1) Confidence 0.69 Published 2008 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 18956709 Disease Relevance 0.07 Pain Relevance 0
RT-PCR and Western-blotting were used to detect the mRNA and protein expression of P-type Na+ -K+ -ATPase.
Transcription (expression) of P-type Na+ -K+ -ATPase
2) Confidence 0.69 Published 2008 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 18956709 Disease Relevance 0.08 Pain Relevance 0
RESULTS: The mRNA and protein expression levels and activity of P-type Na+ -K+ -ATPase in the trigeminal ganglion and trigeminocervical complex of the model group were 0.72 +/- 0.05, 0.59 +/- 0.05, and 5.21 +/- 0.51 respectively, and the mRNA and protein expression levels and activity of P-type Na+ -K+ -ATPase in the cortex of frontal lobe of the model group were 0.70 +/- 0.05, 0.60 +/- 0.05, and 3.61 +/- 0.49 respectively, all significantly lower than those of the control group (0.83 +/- 0.10, 0.67 +/- 0.06, 6.53 +/- 0.73, 0.81 +/- 0.08, 0.71 +/- 0.09, and 6.61 +/- 0.73 respectively, all P < 0.05).
Transcription (levels) of P-type Na+ -K+ -ATPase in trigeminal ganglion
3) Confidence 0.69 Published 2008 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 18956709 Disease Relevance 0.06 Pain Relevance 0
RESULTS: The mRNA and protein expression levels and activity of P-type Na+ -K+ -ATPase in the trigeminal ganglion and trigeminocervical complex of the model group were 0.72 +/- 0.05, 0.59 +/- 0.05, and 5.21 +/- 0.51 respectively, and the mRNA and protein expression levels and activity of P-type Na+ -K+ -ATPase in the cortex of frontal lobe of the model group were 0.70 +/- 0.05, 0.60 +/- 0.05, and 3.61 +/- 0.49 respectively, all significantly lower than those of the control group (0.83 +/- 0.10, 0.67 +/- 0.06, 6.53 +/- 0.73, 0.81 +/- 0.08, 0.71 +/- 0.09, and 6.61 +/- 0.73 respectively, all P < 0.05).
Transcription (expression) of P-type Na+ -K+ -ATPase in trigeminal ganglion
4) Confidence 0.69 Published 2008 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 18956709 Disease Relevance 0.07 Pain Relevance 0
[The effect of psychotropic substances on synaptosomal uptake of gamma-aminobutyric H3-acid and the activity of Na,K-ATPase].
Transcription (activity) of Na,K-ATPase
5) Confidence 0.69 Published 1976 Journal Biull Eksp Biol Med Section Title Doc Link 129178 Disease Relevance 0 Pain Relevance 0.20
We have previously demonstrated that chronic infusion of supraphysiological doses of AngII in normal rats was associated with significantly increased abundance and apical expression level of the Na-H exchanger NHE3 and Na-K-2Cl cotransporter BSC-1 in medullary thick ascending limbs (mTAL), whereas Na,K-ATPase and electroneutral Na-HCO3 cotransporter (NBCn1) levels remained unchanged (10).
Transcription (abundance) of Na,K-ATPase in ascending limbs
6) Confidence 0.17 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2808601 Disease Relevance 0.32 Pain Relevance 0

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