INT102105

Context Info Confidence 0.55 First Reported 2002 Last Reported 2008 Negated 0 Speculated 1 Reported most in Body Documents 3 Total Number 4 Disease Relevance 0.85 Pain Relevance 0.38

signal transduction (Olfr544) signal transducer activity (Olfr544)

Anatomy Link Frequency central nervous system 1 Olfr544 (Mus musculus)

Pain Link Frequency Relevance Heat opioid receptor 8 100.00 Central nervous system 1 100.00 Endogenous opioid 1 100.00 alcohol 1 93.44 anesthesia 2 50.00 Paracetamol 3 5.00 pruritus 1 5.00 painful pain 1 5.00

Disease Link Frequency Relevance Heat Diarrhoea 116 92.88 Keloid Scars 3 85.24 Malaria 17 85.08 Acquired Immune Deficiency Syndrome Or Hiv Infection 3 83.16 Fever 27 73.64 Lower Respiratory Tract Infection 6 5.00 Blister 4 5.00 Vomiting 2 5.00 Disease 2 5.00 Bacterial Respiratory Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

RESULTS: It was possible to analyze the usage and the utilization of ORs at the hospital for each day of the year since 1997.

Spec (analyze) Localization (utilization) of ORs

1) Confidence 0.55 Published 2002 Journal Methods Inf Med Section Body Doc Link 11933770 Disease Relevance 0 Pain Relevance 0

Localization of ORs was examined by immunofluorescence staining and quantitation of ORs was performed by real-time polymerase chain reaction (PCR).

Localization (Localization) of ORs

2) Confidence 0.12 Published 2008 Journal Br. J. Dermatol. Section Body Doc Link 18284397 Disease Relevance 0.09 Pain Relevance 0

Families could borrow from a neighbour or sell some of their belongings to purchase ORS and zinc recommended for their sick children, and intensive marketing of zinc might convince them to do this on a regular basis.

Localization (purchase) of ORS

3) Confidence 0.04 Published 2008 Journal Journal of Health, Population, and Nutrition Section Body Doc Link PMC2740667 Disease Relevance 0.76 Pain Relevance 0

BACKGROUND: Ethanol consumption is thought to enhance the release of endogenous opioids acting at opioid receptors (ORs) in the central nervous system.

Localization (release) of ORs in central nervous system associated with endogenous opioid, central nervous system and opioid receptor

4) Confidence 0.02 Published 2004 Journal Alcohol. Clin. Exp. Res. Section Abstract Doc Link 14745307 Disease Relevance 0 Pain Relevance 0.38

General Comments

This test has worked.